instance_of tequila and tonic
Tonic ___MASK28___ ( or Indian tonic ___MASK28___ ) is a carbonated soft drink in which quinine is dissolved . Originally used as a prophylactic against malaria , tonic ___MASK28___ usually now has a significantly lower quinine content and is consumed for its distinctive bitter flavour . It is often used in mixed drinks , particularly in gin and tonic . A ___MASK82___ , spirit , liquor , hard liquor or hard alcohol is an ___MASK52___ produced by distillation of a mixture produced from alcoholic ___MASK83___ . This process purifies it and removes diluting components like ___MASK28___ , for the purpose of increasing its proportion of alcohol content ( commonly expressed as alcohol by volume , ABV ). As distilled beverages contain more alcohol , they are considered " harder "  in North America , the term " hard liquor " is used to distinguish distilled beverages from undistilled ones . Tequila and Tonic is a non - standard ___MASK95___ beverage also known as a TnT , Teqtonic . The ___MASK45___ is made with a 2 : ___MASK66___ ratio of Tonic ___MASK28___ to Tequila and is served with lemon or lime wedges on ice . Agave ( US : , UK : , Anglo - Hispanic : ) is a ___MASK39___ of monocots native to the hot and arid regions of Mexico and the Southwestern United States . Some agave species are also native to tropical areas of South America . The plants are perennial , but each rosette flowers once and then dies ( see semelparity ). Some species are known by the name " century plant ". A ___MASK43___ is a beverage in which two or more ingredients are mixed . Some mixed drinks contain liquor ; others are non - alcoholic . Jalisco , officially the Free and ___MASK46___ of Jalisco , is one of the 31 states which , with the Federal District , comprise the 32 Federal Entities of Mexico . It is located in Western Mexico and divided into 125 municipalities , and its ___MASK55___ city is Guadalajara . Jalisco is one of the most important states in Mexico because of its natural resources as well as its ___MASK56___ . Many of the characteristic traits of Mexican culture , particularly outside Mexico City , are originally from Jalisco , such as mariachi , ranchera music , birria , tequila , jaripeo , etc . Hence , the state ' s motto : " Jalisco es México ." Economically , it is ranked third in the country , with industries centered in the Guadalajara metropolitan area , the second largest metropolitan area in Mexico . The state is home to two significant indigenous populations , the Huichols and the Nahuas . There is also a significant foreign population , mostly retirees from the United States and Canada , living in the Lake Chapala and Puerto Vallarta areas . Mezcal ( or mescal ) is a distilled ___MASK52___ made from any type of agave plant native to Mexico . The word " mezcal " comes from Nahuatl " mexcalli " " metl " and " ixcalli " which means " oven - cooked agave ". In chemistry , esters are ___MASK23___ compounds derived from an ___MASK53___ ( organic or inorganic ) in which at least one  OH ( hydroxyl ) group is replaced by an  O  alkyl ( alkoxy ) group . Usually , esters are derived from a ___MASK25___ and an alcohol . Glycerides , which are fatty ___MASK53___ esters of glycerol , are important esters in biology , being one of the main classes of lipids , and making up the bulk of animal fats and vegetable oils . Esters with low molecular weight are commonly used as fragrances and found in essential oils and pheromones . Phosphoesters form the backbone of DNA molecules . Nitrate esters , such as nitroglycerin , are known for their explosive properties , while polyesters are important plastics , with monomers linked by ___MASK27___ moieties . Tequila is a regionally specific ___MASK85___ for a ___MASK82___ made from the blue agave plant , primarily in the area surrounding the city of Tequila , northwest of Guadalajara , and in the highlands (" Los Altos ") of the central western Mexican state of Jalisco . Although tequila is similar to mezcal , modern tequila differs somewhat in the method of its production , in the use of only blue agave plants , as well as in its regional specificity . Tequila is commonly served neat in Mexico and as a shot with salt and lime across the rest of the world . ___MASK95___ is the name for a ___MASK29___ of mixed alcoholic drinks that are composed of an alcoholic ___MASK19___ spirit and a larger proportion of a non - alcoholic mixer . ___MASK9___ is a spirit which derives its predominant flavour from juniper berries (" Juniperus communis "). From its earliest origins in the Middle Ages , ___MASK9___ has evolved from a herbal ___MASK58___ to an object of commerce in the spirits industry . ___MASK9___ was developed on the basis of the older jenever , and became popular in Great Britain ( particularly in London ) when William of Orange , leader of the Dutch Republic , occupied the English , Scottish , and Irish thrones with his wife Mary . ___MASK9___ is one of the broadest categories of spirits , represented by products of various origins , styles , and flavour profiles that all revolve around juniper as a common ingredient . Malaria is a mosquito - borne ___MASK73___ affecting humans and other animals caused by parasitic protozoans ( a group of ___MASK81___ - celled microorganisms ) belonging to the " Plasmodium " type . Malaria causes symptoms that typically include fever , fatigue , ___MASK3___ , and headaches . In severe cases it can cause yellow skin , seizures , coma , or death . Symptoms usually begin ten to fifteen days after being bitten . If not properly treated , people may have recurrences of the disease months later . In those who have recently survived an infection , reinfection usually causes milder symptoms . This partial resistance disappears over months to years if the person has no continuing exposure to malaria . The disease is most commonly transmitted by an infected female " Anopheles " mosquito . The mosquito bite introduces the parasites from the mosquito ' s saliva into a person ' s blood . The parasites travel to the liver where they mature and reproduce . Five species of " Plasmodium " can infect and be spread by humans . Most deaths are caused by " P . falciparum " because " P . vivax ", " P . ovale ", and " P . malariae " generally cause a milder form of malaria . The species " P . knowlesi " rarely causes disease in humans . Malaria is typically diagnosed by the microscopic examination of blood using blood films , or with antigen - based rapid diagnostic tests . Methods that use the polymerase chain reaction to detect the parasite ' s DNA have been developed , but are not widely used in areas where malaria is common due to their cost and complexity . The risk of disease can be reduced by preventing mosquito bites through the use of mosquito nets and insect repellents , or with mosquito control measures such as spraying insecticides and draining standing water . Several medications are available to prevent malaria in travellers to areas where the disease is common . Occasional doses of the combination medication sulfadoxine / pyrimethamine are recommended in infants and after the first trimester of pregnancy in areas with high rates of malaria . Despite a need , no effective vaccine exists , although efforts to develop one are ongoing . The recommended treatment for malaria is a combination of antimalarial medications that includes an artemisinin . The second medication may be either mefloquine , lumefantrine , or sulfadoxine / pyrimethamine . Quinine along with doxycycline may be used if an artemisinin is not available . It is recommended that in areas where the disease is common , malaria is confirmed if possible before treatment is started due to concerns of increasing drug resistance . Resistance among the parasites has developed to several antimalarial medications ; for example , chloroquine - resistant " P . falciparum " has spread to most malarial areas , and resistance to artemisinin has become a problem in some parts of Southeast Asia . The disease is widespread in the tropical and subtropical regions that exist in a broad band around the equator . This includes much of Sub - Saharan Africa , Asia , and Latin America . In 2015 , there were 214 million cases of malaria worldwide resulting in an estimated 438 , 000 deaths , 90 % of which occurred in Africa . Rates of disease have decreased from 2000 to 2015 by 37 %, but increased from 2014 during which there were 198 million cases . Malaria is commonly associated with poverty and has a major negative effect on economic development . In Africa , it is estimated to result in losses of US $ 12 billion a year due to increased healthcare costs , lost ability to work , and negative effects on tourism . A ___MASK9___ and tonic is a ___MASK95___ ___MASK50___ made with ___MASK9___ and tonic water poured over ice . It is usually garnished with a slice or wedge of lime . The amount of ___MASK9___ varies according to taste . Suggested ratios of ___MASK9___ to tonic are between ___MASK66___ : ___MASK66___ and ___MASK66___ : 3 .