subclass_of trailhead
A trailhead is the ___MASK1___ at which a ___MASK34___ begins , where the ___MASK34___ is often intended for hiking , biking , horseback riding , or off - road vehicles . Modern trailheads often contain rest rooms , maps , sign posts and distribution centers for informational brochures about the ___MASK34___ and its features , and parking areas for vehicles and trailers . Historically , the cities located at the terminus of major pathways for foot traffic such as the Natchez Trace and the Chisholm ___MASK34___ were also known as trailheads . For mountain climbing and hiking , the elevation of the trailhead above sea level is given to give an idea of how high the mountain is above the average terrain . The ___MASK29___ railhead is a railway term with two distinct meanings , depending upon its context . A trading post or trading ___MASK13___ was a place or establishment where the trading of goods took place ; the term is generally used , in modern parlance , in reference to such establishments in historic Northern America , although the practice long predates that ___MASK32___ ' s colonization by Europeans . The preferred travel route to a trading post or between trading posts , was known as a trade route . Natchez is the ___MASK37___ seat and only city of Adams ___MASK37___ , Mississippi , United States . Natchez has a total ___MASK4___ of 15 , 792 ( as of the 2010 ___MASK88___ ). Located on the Mississippi River across from Vidalia in Concordia ___MASK85___ , Louisiana , Natchez was a prominent city in the antebellum years , a center of cotton planters and Mississippi River trade . Jesse Chisholm ( circa 1805 - ___MASK82___ 4 , 1868 ) was a mixed blood Cherokee ___MASK67___ trader . His name is most famous because of the namesake cattle ___MASK34___ , which he originally scouted and developed to supply his various trading posts among the Plains Indians in what is now western Oklahoma . Although Chisholm died before the heyday of the Texas - to - Kansas cattle drives , he was nevertheless a participant in several important events in Texas and Oklahoma ___MASK41___ . The Natchez Trace , also known as the " Old Natchez Trace ", is a historic ___MASK3___ ___MASK34___ within the United States which extends roughly from Natchez , Mississippi , to Nashville , Tennessee , linking the Cumberland , Tennessee , and Mississippi Rivers . The Chisholm ___MASK34___ was a ___MASK34___ used in the post - Civil War era to drive cattle overland , from ranches in Texas to Kansas railheads . The portion of the ___MASK34___ marked by Jesse Chisholm went from his southern trading post near the Red River , to his northern trading post near Kansas City , Kansas . Texas is the ___MASK16___ largest state in the United States by both area and ___MASK4___ . Geographically located in the south central part of the country , Texas shares borders with the U . S . states of Louisiana to the east , Arkansas to the northeast , Oklahoma to the north , New Mexico to the west , and the Mexican states of Chihuahua , Coahuila , Nuevo León , and Tamaulipas to the southwest , while the Gulf of Mexico is to the southeast . Proteins ( or ) are large biomolecules , or macromolecules , consisting of one or more long chains of amino ___MASK10___ residues . Proteins perform a vast array of functions within organisms , including catalysing metabolic reactions , DNA replication , responding to stimuli , and transporting molecules from one ___MASK69___ to another . Proteins differ from one another primarily in their sequence of amino acids , which is dictated by the nucleotide sequence of their genes , and which usually results in protein folding into a specific three - dimensional structure that determines its activity . Apoptosis ( from ___MASK6___  " falling off ") is a process of programmed ___MASK36___ death that occurs in multicellular organisms . Biochemical events ___MASK97___ to characteristic ___MASK36___ changes ( ___MASK47___ ) and death . These changes include blebbing , ___MASK36___ shrinkage , nuclear fragmentation , chromatin condensation , chromosomal DNA fragmentation , and global mRNA decay . Between 50 and 70 billion cells die each ___MASK100___ due to apoptosis in the average human adult . For an average child between the ages of 8 and 14 , approximately 20 billion to 30 billion cells die a ___MASK100___ . Kansas is a U . S . ___MASK84___ located in the Midwestern United States . Its ___MASK79___ is Topeka and its largest city is Wichita . Kansas is named after the Kansa Native American tribe , which inhabited the area . The tribe ' s name ( natively "") is often said to mean " people of the wind " or " people of the south wind ", although this was probably not the term ' s original meaning . For thousands of years , what is now Kansas was home to numerous and diverse Native American tribes . Tribes in the eastern part of the ___MASK84___ generally lived in villages along the river valleys . Tribes in the western part of the ___MASK84___ were semi - nomadic and hunted large herds of bison . Kansas ___MASK89___ ( often abbreviated as " KCK " to differentiate it from its adjacent namesake , Kansas ___MASK89___ , Missouri ) is the third - largest ___MASK89___ in the state of Kansas , the ___MASK37___ seat of Wyandotte ___MASK37___ , and the third - largest ___MASK89___ of the Kansas ___MASK89___ ___MASK38___ . It is part of a consolidated ___MASK89___ - ___MASK37___ ___MASK52___ known as the " Unified ___MASK52___ ". Wyandotte ___MASK37___ also includes the independent cities of Bonner Springs and Edwardsville . As of the 2010 census , the ___MASK89___ had a population of 145 , 786 residents . It is situated at Kaw Point , which is the junction of the Missouri and Kansas rivers . Nashville is the ___MASK79___ of the U . S . state of Tennessee and the county seat of Davidson County . It is located on the Cumberland River in the north central part of the state . The city is a center for the music , healthcare , publishing , banking and transportation industries , and home to numerous colleges and universities . Reflecting the city ' s position in state ___MASK52___ , Nashville is home to the Tennessee Supreme Court ' s courthouse for Middle Tennessee . It is known as a center of the country music industry , earning it the nickname " Music City U . S . A ." In the ___MASK54___ of cell biology , TNF - related apoptosis - inducing ligand ( ___MASK34___ ), is a protein functioning as a ligand that induces the process of cell death called apoptosis . Mississippi is a ___MASK84___ in the southern region of the United States , with ___MASK64___ of its southern ___MASK27___ formed by the Gulf of Mexico . Its ___MASK71___ ___MASK27___ is formed by the Mississippi River . ___MASK36___ biology ( formerly called cytology , from the Greek  , " kytos ", " vessel ") is a branch of biology that studies the different structures and functions of the ___MASK36___ and focuses mainly on the idea of the ___MASK36___ as the basic unit of life . ___MASK36___ biology explains the ___MASK93___ , organization of the organelles they contain , their physiological properties , metabolic processes , signaling pathways , life cycle , and interactions with their environment . This is done both on a microscopic and molecular level as it encompasses prokaryotic cells and eukaryotic cells . Knowing the components of cells and how cells work is fundamental to all biological sciences ; it is also essential for research in bio - medical fields such as cancer , and other diseases . Research in ___MASK36___ biology is closely related to ___MASK23___ , biochemistry , molecular biology , immunology , and developmental biology .