Photos: Boxing legend Muhammad Ali  Since winning a gold medal in the 1960 Olympics, Muhammad Ali has never been far from the public eye. Take a look at the life and career of Ali, the three-time heavyweight boxing champion who called himself "The Greatest."  Photos: Boxing legend Muhammad Ali  Ali, then known as Cassius Clay, poses in his hometown of Louisville, Kentucky, prior to his amateur boxing debut in 1954. He was 12 years old and 85 pounds. As an amateur, he won 100 out of 108 fights.  Photos: Boxing legend Muhammad Ali  Ali rose to prominence at the 1960 Olympic Games in Rome, where he claimed a gold medal in the light-heavyweight division.  Photos: Boxing legend Muhammad Ali  Ali boldly predicted it would take him five rounds to knock out British boxer Henry Cooper ahead of their bout in London in 1963. The fight was stopped in the fifth round as Cooper was bleeding heavily from a cut around his eye.  Photos: Boxing legend Muhammad Ali  Patrick Power, 6, takes on Ali in the ring in 1963. Patrick was taking boxing lessons after getting bullied.  Photos: Boxing legend Muhammad Ali  Ali poses for a picture with The Beatles in Miami, during the run-up to his heavyweight title fight against Sonny Liston in 1964.  Photos: Boxing legend Muhammad Ali  Ali celebrates after defeating Liston in Miami on February 25, 1964. Upon becoming world heavyweight champion for the first time, Ali proclaimed, "I am the greatest!"  Photos: Boxing legend Muhammad Ali  Ali relaxes after his win over Liston in 1964. At 22, he became the youngest boxer to take the heavyweight title from a reigning champion.  Photos: Boxing legend Muhammad Ali  Civil rights activist Malcolm X, left, takes a picture of a tuxedo-clad Ali surrounded by jubilant fans in March 1964. Shortly after the Liston fight, Ali announced that he had joined the Nation of Islam and changed his name from Cassius Clay.  Photos: Boxing legend Muhammad Ali  Known for being as quick with his mouth as he was with his hands, Ali often taunted his opponents. He famously said he could "float like a butterfly, sting like a bee."  Photos: Boxing legend Muhammad Ali  Ali prepares to defend his heavyweight title in 1965.  Photos: Boxing legend Muhammad Ali  Ali stands over Liston during their rematch in Lewiston, Maine, on May 25, 1965.  Photos: Boxing legend Muhammad Ali  Ali eats at a restaurant in 1965.  Photos: Boxing legend Muhammad Ali  The referee pushes Ali to a neutral corner as Floyd Patterson slumps to the canvas in November 1965. The fight was stopped at the end of the 12th round and Ali was declared the winner.  Photos: Boxing legend Muhammad Ali  Ali signs an autograph for a fan in 1966.  Photos: Boxing legend Muhammad Ali  Ali visits a children's home in London in May 1966.  Photos: Boxing legend Muhammad Ali  Ali trains for his second fight against British champion Henry Cooper in May 1966.  Photos: Boxing legend Muhammad Ali  British talk-show host Eamonn Andrews shares a laugh with Ali in May 1966.  Photos: Boxing legend Muhammad Ali  Ali lands a right to the head of Brian London during their bout in London on August 6, 1966. Ali won by a knockout in the third round.  Photos: Boxing legend Muhammad Ali  Ali looks in his hotel-room mirror in February 1967.  Photos: Boxing legend Muhammad Ali  The referee counts as Ali looks down at Zora Folley during a championship fight in New York on March 23, 1967. Ali won by a knockout in the seventh round.  Photos: Boxing legend Muhammad Ali  As a conscientious objector to the Vietnam War, Ali refused induction into the U.S. Army in April 1967. Here, top athletes from various sports gather to support Ali as he gives his reasons for rejecting the draft. Seated in the front row, from left to right, are Bill Russell, Ali, Jim Brown and Kareem Abdul-Jabbar.  Photos: Boxing legend Muhammad Ali  Photos: Boxing legend Muhammad Ali  On November 2, 1970, Ali returned to the ring for his first professional fight in three years. He defeated Jerry Quarry in the third round.  Photos: Boxing legend Muhammad Ali  Known as the "Fight of the Century," Ali and Joe Frazier split a $5 million purse to fight for Frazier's title on March 8, 1971, in New York. Frazier won by unanimous decision, handing Ali his first professional loss.  Photos: Boxing legend Muhammad Ali  Ali toys with the finely combed hair of television sports commentator Howard Cosell before the start of the Olympic boxing trials in August 1972.  Photos: Boxing legend Muhammad Ali  Ali and Frazier appear on "The Dick Cavett Show" in January 1974. The two got into a brawl in ABC's New York studio and were fined $5,000 each.  Photos: Boxing legend Muhammad Ali  Ali passes a cheering crowd in Kinshasa, Zaire (now the Democratic Republic of Congo), on September 28, 1974. Ali was in the country to fight George Foreman, who had recently defeated Frazier to win the title.  Photos: Boxing legend Muhammad Ali  Photos: Boxing legend Muhammad Ali  Ali addresses a Nation of Islam meeting in London in December 1974. The following year, Ali left the Nation and embraced a more mainstream Islamic faith.  Photos: Boxing legend Muhammad Ali  Ali offers advice to future opponent Richard Dunn in March 1976. Ali defeated Dunn in the fifth round two months later. It was his last knockout win.  Photos: Boxing legend Muhammad Ali  Ali and his third wife, Veronica, second from right, visit the Kremlin in Moscow in June 1978. The two were married from 1977 to 1986. Ali was married four times.  Photos: Boxing legend Muhammad Ali  Ali takes his daily run along a Pennsylvania country road, shrouded in early morning fog, in 1978.  Photos: Boxing legend Muhammad Ali  Ali takes a hit from Leon Spinks during their title fight in New Orleans on September 15, 1978. Ali won by unanimous decision, regaining the title he lost to Spinks earlier that year.  Photos: Boxing legend Muhammad Ali  Ali sits with his daughters Laila and Hana at the Grosvenor House in London in December 1978. He briefly retired from professional boxing the following year.  Photos: Boxing legend Muhammad Ali  Ali came out of retirement on October 2, 1980, for a title fight with Larry Holmes and a guaranteed purse of $8 million. Holmes won easily, beating up Ali until the fight was stopped after the 10th round.  Photos: Boxing legend Muhammad Ali  Ali and Trevor Berbick weigh in for their fight in the Bahamas in December 1981. Berbick won by unanimous decision. It was Ali's last professional fight.  Photos: Boxing legend Muhammad Ali  Ali prays at a mosque in Cairo in October 1986. Two years prior, he revealed that he had Parkinson's syndrome, a disorder of the central nervous system.  Photos: Boxing legend Muhammad Ali  In 1990, Ali met with Iraqi President Saddam Hussein to negotiate the release of 15 American hostages in Iraq and Kuwait. Here, Ali leaves Iraq with the hostages on December 2, 1990.  Photos: Boxing legend Muhammad Ali  Ali lights the Olympic torch at the 1996 Summer Olympics in Atlanta.  Photos: Boxing legend Muhammad Ali  Juan Antonio Samaranch, president of the International Olympic Committee, gives Ali a replacement gold medal in 1996. Ali had thrown his 1960 gold medal into the Ohio River after he was criticized for not fighting in Vietnam.  Photos: Boxing legend Muhammad Ali  Ali and his fourth wife, Lonnie, unveil his special-edition Wheaties box in February 1999. The box marked the cereal's 75th anniversary, and it was the first time a boxer appeared on the cover.  Photos: Boxing legend Muhammad Ali  Actor Arnold Schwarzenegger raises Ali's hand during the Celebrity Fight Night charity event in Phoenix in March 2002. Schwarzenegger was presented with the Muhammad Ali Humanitarian Award for his work with the Muhammad Ali Parkinson Research Foundation, the Inner-City Games Foundation and the Special Olympics. The award was presented by former CNN host Larry King, left.  Photos: Boxing legend Muhammad Ali  Ali arrives in Kabul, Afghanistan, in November 2002 for a three-day goodwill mission as a special guest of the United Nations. He was appointed as a U.N. Messenger of Peace in 2000.  Photos: Boxing legend Muhammad Ali  U.S. President George W. Bush presents Ali with the Presidential Medal of Freedom, the nation's highest civilian honor, on November 9, 2005.  Photos: Boxing legend Muhammad Ali  Members of the media watch a video of Ali before the grand opening of the Muhammad Ali Center in Louisville, Kentucky, in November 2005.  Photos: Boxing legend Muhammad Ali  Ali's wife, Lonnie, watches as actress Alfre Woodard presents him with the President's Award during the 2009 NAACP Image Awards in Los Angeles.  Photos: Boxing legend Muhammad Ali  On May 24, 2011, Ali appears at the National Press Club in Washington to publicly appeal to Iranian officials for the release of captive hikers Shane Bauer and Josh Fattal. The hikers were released in September 2011, more than two years after their detention.  Photos: Boxing legend Muhammad Ali  Ali poses during a photo shoot outside his home in Paradise Valley, Arizona, in January 2012.  Photos: Boxing legend Muhammad Ali  Ali poses for a picture with, from left, Greg Fischer, Len Amato, daughter Laila Ali and Donald Lassere during the U.S. premiere of the HBO film "Muhammad Ali's Greatest Fight" in October 2013.  Photos: Boxing legend Muhammad Ali  A boxing robe worn by Ali, which belonged to the late country singer Waylon Jennings, went up for auction in 2014.  Photos: Boxing legend Muhammad Ali  Ali is seen with singer Carrie Underwood at a charity event in Phoenix in April.
Fox and his foundation's CEO Todd Sherer say we should honor Ali's fortitude in fighting Parkinson's with a renewed commitment to research