 genome - wied associetion stady  (GWAS)  antey emti ?
 genomics ‌ loo ,  genome - wied associetion stady  (GWA  stady ,  ledha  GWAS),  anede edaina vaividhyam ooka lakshanamtho sambandam kaligi undhoo ledo telusukovadaniki vividha vyaktulalo genyu - vyaapta genyu vaividhyaala samithi yokka pariseelanaatmaka adhyayanam . GWA  adhyayanalu saadharanamga singel - nucleotide polymorphism ‌ lu  (SNP lu )  mariyu pradhaana human vyaadhula vento lakshanhaala Madhya anubandhaalapai drhushti pedathaayi ,  ayithe itara genyu vaividhaylu mariyu itara jeevulaku samaanamgaa vartinchavachhu .

 human detaku vartimpajesinappudu , GWA  adhyayanalu ooka nirdishta lakshanam ledha vyaadhiki sambamdhinchina vibhinna samalakshanhaalanu kaligi unna palgonevari  DNA ni saripolchutaayi .  yea paalgonaevaaru vyaadhi unna vyaktulu  ( casulu )  mariyu vyaadhi laeni vyaktulu  ( niyantranalu )  kaavachhu ledha varu ooka nirdishta lakshanam choose vibhinna samalakshanhaalu unna vyaktulu kaavachhu ,  udaharanaku raktapotu .  yea vidhanaanni phinotipe - phast ani pilustharu ,  dheenilo paalgonaevaaru janyuroopam - modatiki viruddhamgaa vaari clinically vyakteekatana ( l )  dwara modhata vargeekarinchabadataaru .  prathi vyakti  DNA  yokka namuunaanu istaadu ,  deeni nundi millionla koddi genyu vaividhaylu  SNP  shrenulanu upayoginchi chadavabadatayi .  vyaadhi unnavaarilo ooka rakamaina vaividhyam  ( ooka yugma vikalpam )  ekkuvaga vasthumdani mukhyamaina gananka sakshyam vunte ,  aa vaividhyam vyaadhitoe sambandam kaligi umtumdi .  anubandha  SNP lu vyaadhi pramaadaanni prabhaavitam chese human janyuvu yokka praantaanni gurthinchadaaniki pariganhinchabadataayi .

GWA  adhyayanalu takuva sankhyalo mundhuga paerkonna genyu praantaalanu pratyekamgaa pariikshinche paddhatulaku bhinnangaa ,  motham janyuvunu parisoedhistaayi .  anevalla , GWAS  anede genyu - nirdishta abhyardhi - aadhaaritha adhyayanalaku viruddhamgaa ,  abhyardhi - aadhaaritha vidhaanam . GWA  adhyayanalu ooka vyaadhitoe sambandam unna  DNA loni  SNP lu mariyu itara vaividhyaalanu gurtistaayi ,  ayithe avi e janyuvulaku kaaranamavutunnaayo vaati swantamgaa perkonalevu .

2002 loo prachurinchabadina modati vijayavantamaina  GWAS  myocardial inforction girinchi adhyayanam chesindi .  vayassu - sambandhitha macchala ksheenatha unna rogulanu parisoedhimchae mailuraayi  GWA 2005  adhyyanamlo yea adhyyana rupakalpana amalu cheyabadindhi mariyu aarogyakaramaina niyanthranalatho polisthe gananeeyamgaa maarchabadina yugma vikalpa pounahpunyamtho remdu  SNP lanu kanugonnaru . 2017  natiki , 3,000  kante ekuva human  GWA  adhyayanalu  1,800  Morbi mariyu lakshanaalanu pariseelinchaayi mariyu velaadi  SNP  sanghalu kanugonabaddaayi .  arudaina janyuparamaina vyaadhula vishayamlo tappa ,  yea sanghalu chaaala balaheenamgaa unnayi ,  conei avi chaaala pramaadaanni vivarinchalekapoyina ,  avi mukhyamainaviga umdae janyuvulu mariyu margalapai antardrushtini andistaayi .