 zean ‌ bass antey emti ?
GeneBass  anede ksheerada kanaalalo janyuvula yokka high - throoput functionally visleshana choose  CRISPR-Cas9  screeniing plaat ‌ faram .  zean ‌ bass plaat ‌ faram parisodhakulu aasaktigala janyuvulanu cramapadhhatilo sakriyam cheyadanki ledha anachiveyadaaniki mariyu kanaala vistarana ,  bheedam mariyu manugada vento selular prakriyalapai vaati prabhaavaalanu adhyayanam cheyadanki anumatistundi .  sistom human ledha mause janyuvuloni prathi janyuvunu lakshyangaa cheesukuni guuide  RNA l pool cheyabadina lentiviral libraryni upayogistundi ,  idi vairal trance ‌ duction upayoginchi kanaalaloki pravesapettabadutundi .  guuide  RNA lu prathi janyuvu yokka trance ‌ cryption praarambha cyte ‌ laku prakkanae unna janyuvu yokka nirdishta praantaalanu lakshyangaa cheskovadaniki ruupomdimchabaddaayi ,  idi nirdishta mariyu samardhavanthamaina genyu kriyaaseelatanu ledha anachivetanu anumatistundi .  zean ‌ bass prayoogaalu saadharanamga peddha sankhyalo kanaala trance ‌ duction ‌ nu kaligi untai ,  aa tarwata nirdishta aasakti gala samalakshanaala aadhaaramga kanaala empika ledha kramabaddheekarana umtumdi .  empikaku mundhu mariyu tarwata guuide  RNA  liibrary yokka high - throoput sequencing nirdishta selular prakriyalaku avasaramaina ledha vyaadhi maargaallo paalgonae janyuvulanu gurthinchadaaniki upayoeginchavachchu .