CRISPR  antey emti ?
CRISPR ( clustered regular inter ‌ spaced shortt polyndromic repeat ‌ laku sankshiptha roopam )  anede bacteria mariyu archia vento procaraotic jeevula janyuvulalo kanipincha  DNA  shrenula kutunbam .  yea seekvensulu gatamlo procaryot ‌ ku sokina bacteriophase ‌ l  DNA  shakalalu nundi teesukobaddaayi .  tadupari antuvyaadhula samayamlo saaroopya bacteriophase ‌ l nundi  DNA  nu gurthinchi nasanam cheyadanki ivi upayoginchabadataayi .  anevalla yea seekvensulu procaryot ‌ l yokka antiviral  ( antey anty - faze )  rakshana vyavasthaloo keelaka patra pooshistaai mariyu pondina rooganiroodhaka shakthini andistaayi . CRISPR  sumaarugaa  50%  seakwensed byakteeriyal janyuvulalo mariyu dadapu  90%  seakwensed archaealo kanugonabadindi .

Cas9 ( ledha  "CRISPR- anubandha proteins  9")  anede  CRISPR  sequence ‌ ku anubandhamgaa umdae  DNA  yokka nirdishta tantuvulanu gurthinchadaaniki mariyu vidadeeyadaaniki maargadarsakamgaa  CRISPR  sequence ‌ lanu upayoegimchae ooka enzyme . CRISPR  sequence ‌ lato kalisi  Cas9  enzyme ‌ lu  CRISPR-Cas9  ani piluvabadee saanketikataku aadharaanni yerparustayi ,  vitini jeevulalooni janyuvulanu savarinchadaaniki upayoeginchavachchu .  yea savarna procedure praadhimika jiva parisoedhana ,  biotechnolgy utpattula abhivruddhi mariyu vyaadhula chikitsatho sahaa anek takala aplication ‌ lanu kaligi Pali . CRISPR-Cas9  genome aditing technic abhvruddhini  2020 loo rasayana shaasthramlo nobel bahumati emmanuel charpentier mariyu jnnifer doudnaku andinchindi .

2022 loo ,  uunited stetes paetent mariyu trade ‌ marque offices  ( jokyam  106,115) loo jargina ooka proseeding ‌ loo ,  eucariotic kanaalalo  CRISPR-Cas9  yokka  US  paetent covering aplication yokka aavishkarta feng zhang ani paetent trail mariyu appeel bord nirnayinchindhi .  braad institut .