structurally genomics antey emti ?
structurally genomics ichina janyuvu dwara encode cheyabadina prathi proteins yokka  3- dimensionally nirmaanaanni vivarinchadaaniki prayatnistundi .  yea genyu - aadhaaritha vidhaanam prayoogaathmaka mariyu modaling vidhanala kalaika dwara nirmaanaanni nirnayinche adhika - nirgamaamsa addhatini anumatistundi .  structurally genomics mariyu saampradaya structurally prediction Madhya unna pradhaana vyatyaasam aemitante ,  structurally genomics ooka nirdishta proteins ‌ pai drhushti pettakunda ,  janyuvu dwara ene ‌ kood cheyabadina prathi proteins yokka nirmaanaanni nirnayinchadaniki prayatnistundi .  porthi - genyu srenulu andubatulo unnanduna ,  prayoogaathmaka mariyu modaling vidhanala kalaika dwara structure prediction marinta twaraga cheyavachu ,  pratyekinchi peddha sankhyalo seakwensed genome ‌ lu mariyu gatamlo parishkarinchabadina proteins nirmaanaala labhyata shaasthravetthalanu gatamlo parishkarinchina nirmaanaalapai proteins nirmaanaanni roopondhinchadaaniki anumatistundi . homologs.

 proteins nirmaanam proteins function ‌ thoo daggari sambandam kaligi unnanduna ,  structurally genomics proteins paniteeru girinchi gnaanaanni teliyajeyagala saamardhyaanni kaligi umtumdi .  protein function ‌ lanu visadeekarinchadamto paatu ,  kothha protein madatalu mariyu aushadha aavishkaranhaku sambhaavya lakshyalanu gurthinchadaaniki structurally genomics upayoeginchavachchu .  structurally genomics anede structurally genomics anede genomic sequence ‌ lanu upayoginchi prayoogaathmaka padhathulu ledha telisina structure yokka protein ‌ ki ledha structurally homology aadhaaramga ledha rasayana mariyu bhautika suuthraala aadhaaramga yelanti homology laeni protein ‌ ku sambamdhinchina prayoogaathmaka padhathulu ledha modaling - aadhaaritha vidhanalanu kaligi umtumdi .  edaina telisina nirmaanam .

 saampradaya nirmaana jeevasaastraaniki viruddhamgaa ,  protein paniteeru girinchi edaina teliyakamunde structurally genomics prayathnam dwara protein nirmaanaanni tarachugaa  ( conei allappuduu kadhu )  nirnayinchadam jarudutundhi .  idi structurally bioinformatics ‌ loo kothha savaallanu penchutundi ,  antey dani  3D  nirmaanam nundi proteins paniteerunu nirnayinchadam .

 structurally genomics proteins nirmaanaala yokka adhika nirgamaamsa nirnayaanni nillaki chebutundi .  idi structurally genomics yokka pratyeka kendraalalo nirvahinchabaduthundi .

 chaaala mandhi structurally bialogist ‌ lu vyaktigata proteins ledha proteins groupula nirmaanaalanu anusaristundagaa ,  structurally genomics ‌ loo nipunhulu genome wied scale ‌ loo proteinla nirmaanaalanu anusaristaaru .  idi peddha - stayi cloning ,  vyakteekatana mariyu suddheekarananu suchisthundi .  yea vidhaanam yokka ooka pradhaana prayojanam scale yokka aardika vyvasta .  maroovaipu ,  konni phalita nirmaanaala yokka shaastreeya viluva konnisarlu prashninchabadutundi .  janavari  2006  nundi ooka science kathanam nirmaanaathmaka janyusaastra ksheytraanni vislaeshistumdi .

 protein structure initiative vento structurally genomics yokka ooka prayojanam aemitante ,  shaastreeya samajam kothha nirmaanaalaku ,  alaage clones mariyu proteins vento kaarakaalaku takshana praapyatanu pondutundi .  ooka pratikulata aemitante ,  yea nirmaanaalaloo chaaala varku teliyanu function yokka protein ‌ lu mariyu sambandhitha prachuranalu leavu .  yea nirmaanaathmaka samaachaaraanni visthrutha parisoedhanaa sanghaaniki teliyajeyadaaniki kothha margalu avsaram .  jaint senter far structurally genomics  (JCSG)  yokka bioinformatics korr iteevale adhika - nirgamaamsa nirmaanaathmaka janyusaastra centres nundi udbhavistunna proteins nirmaanaalanu ullekhinchadaaniki open proteins structure ullekhana nett ‌ varey  (TOPSAN)  aney vikee - aadhaaritha vidhanaanni abhivruddhi chesindi .