IGFBP3  modhatisaarigaa eppudi vargeekarinchabadindi ?
 insullin lanty groth factor - binding proteins  3,  dheenini  IGFBP-3  ani kudaa pilustharu ,  idi maanavulalo  IGFBP3  janyuvu dwara encode cheyabadina proteins . IGFBP-3  anede aaru  IGF  binding proteins ‌ lalo okati  (IGFBP-1  nundi  IGFBP-6  varku )  ivi athantha samrakshinchabadina nirmaanaalanu kaligi untai mariyu insullin - vento vruddhi kaarakaalaina  IGF-1  mariyu  IGF-2 lanu adhika anubandhamtho bandhistaayi . IGFBP-7,  konnisarlu yea kutumbamlo cherchabadutundi ,  samrakshinchabadina nirmaana lakshanaalanu ledha adhika  IGF  anubandhaanni panchukodu .  badhuluga , IGFBP-7 IGF1R ni bandhistundi ,  idi  IGF-1  mariyu  IGF-2  binding ‌ lanu addukuntundi ,  falithamgaa apoptosis yerpadutundi .

 function 
IGFBP-3  modhatisaarigaa  1986 loo human plasmalo verucheyabadindi ,  vargeekarinchabadindi mariyu parimaaneekarinchabadindi .  idi prasaranalo ,  kana baahya vaataavaranamlo mariyu kanaala lopala chakkaga namoodhu cheyabadina vidhulanu kaligi Pali .  idi raktapravaahamlo pradhaana  IGF  ravaanhaa protein ,  ikda idi binding proteins , IGF-1  ledha  IGF-2  mariyu yaasid - lebul subunit ledha  ALS  ani piluvabadee mudava proteins ‌ nu kaligi umdae sthiramaina complexes ‌ lalo pradhaanamgaa vruddhi kaarakaalanu kaligi umtumdi .
 insullin - vento groth factor - binding proteins  3  ledha  IGFBP-3  modhatisaarigaa  1986 loo human plasmalo verucheyabadindi ,  vargeekarinchabadindi mariyu parimaaneekarinchabadindi .