Task: Please estimate if the molecule with the SMILES COC(=O)c1c(-c2ccncc2)csc1NC(=O)c1ccoc1C is a potentiator of the estrogen receptor-alpha-coactivator binding.
Result: yes
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-737__names__noun}.
Result: {MUV-737#no&yes}
COC(=O)c1c(-c2ccncc2)csc1NC(=O)c1ccoc1C
COC(=O)c1c(-c2ccncc2)csc1NC(=O)c1ccoc1C
methyl 2-[(2-methylfuran-3-carbonyl)amino]-4-pyridin-4-ylthiophene-3-carboxylate