Task: Please estimate if the compound with the SMILES COc1ccc(N2CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc(F)c4)cc3)CC2)cc1 is a potentiator of the estrogen receptor-alpha-coactivator binding.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-737__names__noun}.
Result: {MUV-737#no&yes}
COc1ccc(N2CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc(F)c4)cc3)CC2)cc1
COc1ccc(N2CCN(C(=O)c3ccc(NS(=O)(=O)c4cccc(F)c4)cc3)CC2)cc1
3-fluoro-N-[4-[4-(4-methoxyphenyl)piperazine-1-carbonyl]phenyl]benzenesulfonamide