Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP2D6 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1cc(Br)c2oc(C3CCNCC3)cc2c1
b. Nc1nc2ccc(OC(F)(F)F)cc2s1
c. Cc1nccn1C[C@H]1CCc2c(c3ccccc3n2C)C1=O
d. FC(F)(F)[C@H](Cl)Br
e. CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(=O)O
Answer: b, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP2D6_Substrate#not &NULL}a {CYP2D6_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP2D6_Substrate%}
Answer: {%multiple_choice_result}