Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP2D6 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) C=C[C@H]1CN2CC[C@H]1C[C@@H]2[C@H](O)c1ccnc2ccc(OC)cc12
(b) OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1
(c) C=CCC1([C@@H](C)CCC)C(=O)NC(=O)NC1=O
(d) COC(=O)[C@H](c1ccccc1Cl)N1CCc2sccc2C1
(e) CCCOCCOC(=O)C1=C(C)NC(C)=C(C(=O)OCCOCCC)C1c1cccc([N+](=O)[O-])c1
Answer: a, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP2D6_Substrate#not &NULL}a {CYP2D6_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP2D6_Substrate%}
Answer: {%multiple_choice_result}