The molecule with the SMILES COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC is not a CYP P450 2D6 substrate.
The molecule with the {SMILES__description} {#representation of |!}{SMILES#} is {CYP2D6_Substrate#not &NULL}a {CYP2D6_Substrate__names__noun}.