User: Is the molecule with the SMILES FC(F)OC(F)(F)[C@@H](F)Cl metabolized by CYP P450 2D6?
Assistant: No, it is not a CYP P450 2D6 substrate.
User: Is the molecule with the {SMILES__description} {SMILES#} {CYP2D6_Substrate__names__verb}?
Assistant: {CYP2D6_Substrate#No&Yes}, it is {CYP2D6_Substrate#not &NULL}a {CYP2D6_Substrate__names__noun}.