The molecule with the SMILES COC(=O)C1=C(C#N)NC(C)=C(C(=O)OC(C)C)[C@H]1c1cccc([N+](=O)[O-])c1 is not a CYP2D6 substrate.
The molecule with the {SMILES__description} {#representation of |!}{SMILES#} is {CYP2D6_Substrate#not &NULL}a {CYP2D6_Substrate__names__noun}.