User: Can you estimate if the molecule with the SMILES COC(=O)C1=C(C#N)NC(C)=C(C(=O)OC(C)C)[C@H]1c1cccc([N+](=O)[O-])c1 is a substrate for CYP P450 2D6?
Assistant: No, this molecule is not metabolized by CYP P450 2D6.
User: Can you {#tell me|derive|estimate!} if the molecule with the {SMILES__description} {SMILES#} is a {CYP2D6_Substrate__names__noun}?
Assistant: {CYP2D6_Substrate#No&Yes}, this molecule is {CYP2D6_Substrate#not &NULL}{CYP2D6_Substrate__names__verb}.