User: Is the molecule with the SMILES COCc1c(C(C)C)nc(C(C)C)c(/C=C\[C@@H](O)C[C@@H](O)CC(=O)O)c1-c1ccc(F)cc1 metabolized by CYP2D6?
Assistant: No, it is not a substrate for CYP2D6.
User: Is the molecule with the {SMILES__description} {SMILES#} {CYP2D6_Substrate__names__verb}?
Assistant: {CYP2D6_Substrate#No&Yes}, it is {CYP2D6_Substrate#not &NULL}a {CYP2D6_Substrate__names__noun}.