User: I want to come up with a SMILES.
Assistant: This sounds very interesting. Should I consider any constraints for the creation?
User: Yes, please. The molecule should not be metabolized by CYP2D6.
Assistant: Ok, this SMILES is not metabolized by CYP2D6: O=C1Cc2cc(CCN3CCN(c4nsc5ccccc45)CC3)c(Cl)cc2N1
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {CYP2D6_Substrate#not &NULL}be {CYP2D6_Substrate__names__verb}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {CYP2D6_Substrate#not &NULL}{CYP2D6_Substrate__names__verb}: {SMILES#}