User: Is the molecule with the SMILES O=C(O)c1ccccc1Nc1cccc(C(F)(F)F)c1 metabolized by CYP2D6?
Assistant: No, it is not a substrate for CYP2D6.
User: Is the molecule with the {SMILES__description} {SMILES#} {CYP2D6_Substrate__names__verb}?
Assistant: {CYP2D6_Substrate#No&Yes}, it is {CYP2D6_Substrate#not &NULL}a {CYP2D6_Substrate__names__noun}.