User: Is the molecule with the SMILES COCc1c(C(=O)OC(C)C)ncc2[nH]c3ccc(OCc4ccccc4)cc3c12 metabolized by CYP P450 2D6?
Assistant: No, it is not a CYP P450 2D6 substrate.
User: Is the molecule with the {SMILES__description} {SMILES#} {CYP2D6_Substrate__names__verb}?
Assistant: {CYP2D6_Substrate#No&Yes}, it is {CYP2D6_Substrate#not &NULL}a {CYP2D6_Substrate__names__noun}.