User: Is the molecule with the SMILES O=C(OC1C[C@@H]2CC3C[C@H](C1)N2CC3=O)c1c[nH]c2ccccc12 metabolized by CYP2D6?
Assistant: Yes, it is a CYP P450 2D6 substrate.
User: Is the molecule with the {SMILES__description} {SMILES#} {CYP2D6_Substrate__names__verb}?
Assistant: {CYP2D6_Substrate#No&Yes}, it is {CYP2D6_Substrate#not &NULL}a {CYP2D6_Substrate__names__noun}.