Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 2D6?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23
(b) COc1cc(C(=O)NS(=O)(=O)c2ccccc2C)ccc1Cc1cn(C)c2ccc(NC(=O)OC3CCCC3)cc12
(c) COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)[C@@H]1c1cccc([N+](=O)[O-])c1
(d) Cc1cccc(Nc2ccncc2S(=O)(=O)NC(=O)NC(C)C)c1
(e) CCC(=O)N(c1ccccc1)C1(COC)CCN(CCn2nnn(CC)c2=O)CC1
Answer: a, b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP2D6_Substrate#not &NULL}a {CYP2D6_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP2D6_Substrate%}
Answer: {%multiple_choice_result}