Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP P450 2D6?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccc(C(=O)N2CCN(c3ccc4c(c3)CCC(=O)N4)CC2)cc1OC
(b) O=C1NCCN1CCN1CCC(c2cn(-c3ccc(F)cc3)c3ccc(Cl)cc23)CC1
(c) Fc1ccc(C(c2ccc(F)cc2)N2CCN(C/C=C/c3ccccc3)CC2)cc1
(d) Clc1ccc([C@@H](Cn2ccnc2)OCc2c(Cl)cccc2Cl)c(Cl)c1
(e) CC(C)c1nc(CN(C)C(=O)N[C@H](C(=O)N[C@@H](Cc2ccccc2)C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)C(C)C)cs1
Answer: a, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP2D6_Substrate#not &NULL}{CYP2D6_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP2D6_Substrate%}
Answer: {%multiple_choice_result}
6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-3,4-dihydro-1H-quinolin-2-one