User: Is the molecule with the SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2ncccn2)CC1 metabolized by CYP2D6?
Assistant: Yes, it is a CYP2D6 substrate.
User: Is the molecule with the {SMILES__description} {SMILES#} {CYP2D6_Substrate__names__verb}?
Assistant: {CYP2D6_Substrate#No&Yes}, it is {CYP2D6_Substrate#not &NULL}a {CYP2D6_Substrate__names__noun}.
8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione