Task: Please answer the multiple choice question.
Question: Which molecules are not a substrate for CYP P450 2D6?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1ccc(C(=O)Nc2ccccc2CC[C@H]2CCCCN2C)cc1
b C=C1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12
c CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1
d COc1cccc([C@@]2(O)CCCC[C@@H]2CN(C)C)c1
e Cc1nnc2n1-c1sc(Br)cc1C(c1ccccc1Cl)=NC2
Answer: b, c, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP2D6_Substrate#not &NULL}a {CYP2D6_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP2D6_Substrate%}
Answer: {%multiple_choice_result}
4-bromo-7-(2-chlorophenyl)-13-methyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaene