User: I want to come up with a SMILES.
Assistant: This sounds very interesting. Should I consider any constraints for the generation?
User: Yes, please. The molecule should not be metabolized by CYP2D6.
Assistant: Ok, this SMILES is not metabolized by CYP2D6: Cc1nnc2n1-c1sc(Br)cc1C(c1ccccc1Cl)=NC2
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {CYP2D6_Substrate#not &NULL}be {CYP2D6_Substrate__names__verb}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {CYP2D6_Substrate#not &NULL}{CYP2D6_Substrate__names__verb}: {SMILES#}
4-bromo-7-(2-chlorophenyl)-13-methyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaene