Problem statement: Answer the multiple-choice question.
Query: Which drug has a -3.067\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccc(-c2cc(=O)oc3cc(OCc4nn[nH]n4)ccc23)cc1
[b] C(=N/Nc1nc(-c2ccccc2)cs1)\c1ccco1
[c] COc1ccc(N2CCN(CCNC(=O)c3c(C)cc(=O)oc3C)CC2)cc1
[d] CNc1nc(OC)nc(N(C#N)CN2C(=O)c3ccccc3S2(=O)=O)n1
[e] CC(NC(=O)c1cccc2ccccc12)c1ccc2c(c1)CCCC2
Answer: c. COc1ccc(N2CCN(CCNC(=O)c3c(C)cc(=O)oc3C)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(CCNC(=O)c3c(C)cc(=O)oc3C)CC2)cc1
COc1ccc(N2CCN(CCNC(=O)c3c(C)cc(=O)oc3C)CC2)cc1
[C][O][C][=C][C][=C][Branch2][Ring2][Ring1][N][C][C][N][Branch2][Ring1][#Branch1][C][C][N][C][=Branch1][C][=O][C][C][Branch1][C][C][=C][C][=Branch1][C][=O][O][C][=Ring1][Branch2][C][C][C][Ring2][Ring1][Ring2][C][=C][Ring2][Ring1][#Branch2]
N-[2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl]-2,4-dimethyl-6-oxopyran-3-carboxamide