Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -2.209\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a N#Cc1ccc(-c2nc3ccc(Br)cc3c(=O)n2O)cc1
b CC(=O)N1CCN(S(=O)(=O)c2cccc(C(=O)Nc3nc4ccccc4[nH]3)c2)CC1
c Cc1ccc(-c2csc(NC(=O)Cc3cccs3)n2)cc1C
d CC(=O)N1CCN(S(=O)(=O)c2ccc(C)cc2)C1C(C)C
e COC(=O)c1cc2sccc2n1Cc1nc(-c2ccc(OC)cc2)oc1C
Answer: e. COC(=O)c1cc2sccc2n1Cc1nc(-c2ccc(OC)cc2)oc1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1cc2sccc2n1Cc1nc(-c2ccc(OC)cc2)oc1C
COC(=O)c1cc2sccc2n1Cc1nc(-c2ccc(OC)cc2)oc1C
[C][O][C][=Branch1][C][=O][C][=C][C][S][C][=C][C][=Ring1][Branch1][N][Ring1][Branch2][C][C][N][=C][Branch1][=N][C][=C][C][=C][Branch1][Ring1][O][C][C][=C][Ring1][Branch2][O][C][=Ring1][=N][C]
methyl 4-[[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl]thieno[3,2-b]pyrrole-5-carboxylate