Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -18.528\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a: COc1ccccc1Nc1nc2c(s1)CCC2
b: CCOc1ccc(NC(=O)Nc2cc(C(C)C)c(O)cc2C)cc1
c: CCCOc1ccc(C(=O)NC(=S)NNC(=O)c2c(-c3ccccc3)noc2C)cc1
d: O=C(CCN1C(=O)/C(=C/c2ccc(F)cc2)SC1=S)NCCCn1ccnc1
Answer: d. O=C(CCN1C(=O)/C(=C/c2ccc(F)cc2)SC1=S)NCCCn1ccnc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCN1C(=O)/C(=C/c2ccc(F)cc2)SC1=S)NCCCn1ccnc1
O=C(CCN1C(=O)/C(=C/c2ccc(F)cc2)SC1=S)NCCCn1ccnc1
[O][=C][Branch2][Ring1][N][C][C][N][C][=Branch1][C][=O][/C][=Branch1][=N][=C][/C][=C][C][=C][Branch1][C][F][C][=C][Ring1][#Branch1][S][C][Ring1][=C][=S][N][C][C][C][N][C][=C][N][=C][Ring1][Branch1]
3-[(5Z)-5-[(4-fluorophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-N-(3-imidazol-1-ylpropyl)propanamide