Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 10.286\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CC(C)/C=N/NC(=O)c1cc(Br)ccc1O
(b) C/C(=N\NC(=O)c1cc(-c2ccncc2)nc2ccccc12)c1ccc(N2CCOCC2)cc1
(c) Cc1ccc(Cn2c(SCC(C)C)nc3c2c(=O)[nH]c(=O)n3C)cc1
(d) CC1=C(C(=O)OCc2ccc3c(c2)OCO3)C(c2ccccc2)NC(=O)N1
(e) CCOc1ccc(NC(=O)CCC(=O)OC)cc1
Answer: b. C/C(=N\NC(=O)c1cc(-c2ccncc2)nc2ccccc12)c1ccc(N2CCOCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C/C(=N\NC(=O)c1cc(-c2ccncc2)nc2ccccc12)c1ccc(N2CCOCC2)cc1
C/C(=N\NC(=O)c1cc(-c2ccncc2)nc2ccccc12)c1ccc(N2CCOCC2)cc1
[C][/C][=Branch2][Ring1][#C][=N][\N][C][=Branch1][C][=O][C][=C][C][Branch1][=Branch2][C][=C][C][=N][C][=C][Ring1][=Branch1][=N][C][=C][C][=C][C][=C][Ring1][S][Ring1][=Branch1][C][=C][C][=C][Branch1][=Branch2][N][C][C][O][C][C][Ring1][=Branch1][C][=C][Ring1][N]
N-[(E)-1-(4-morpholin-4-ylphenyl)ethylideneamino]-2-pyridin-4-ylquinoline-4-carboxamide