Task: Answer the multiple-choice question.
Query: Which drug exhibits a -2.453\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] Cc1ccc(/C=N/NC(=O)c2cccs2)cc1[N+](=O)[O-]
[b] CSC(=S)N/N=C(\C)c1ccccc1
[c] COc1ccc(N2CCN(C(=O)c3ccc(C)cc3Cl)CC2)cc1
[d] COCCNC(=O)c1c(NC(=O)c2ccc(Br)o2)n(Cc2ccccc2)c2nc3ccccc3nc12
[e] Cc1ccc(C(=O)c2ccccc2C(=O)O)cc1C
Answer: c. COc1ccc(N2CCN(C(=O)c3ccc(C)cc3Cl)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(C(=O)c3ccc(C)cc3Cl)CC2)cc1
COc1ccc(N2CCN(C(=O)c3ccc(C)cc3Cl)CC2)cc1
[C][O][C][=C][C][=C][Branch2][Ring1][O][N][C][C][N][Branch1][P][C][=Branch1][C][=O][C][=C][C][=C][Branch1][C][C][C][=C][Ring1][#Branch1][Cl][C][C][Ring1][S][C][=C][Ring2][Ring1][=Branch1]
(2-chloro-4-methylphenyl)-[4-(4-methoxyphenyl)piperazin-1-yl]methanone