Problem statement: Answer the MCQ question.
Question: Which drug has a -4.934\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1cccc(NC(=O)COC(=O)c2ccco2)c1
b. O=c1[nH][nH]c(=O)c2c(NS(=O)(=O)c3ccccc3)cccc12
c. COc1cc(/C=C/C(=O)O)cc(S(=O)(=O)N(CC(C)C)CC(C)C)c1OC
d. CCc1ccc(NC(=O)N[C@H](C(=O)O)C(C)CC)cc1
e. Cc1ccsc1C(=O)Nc1cc(C(C)(C)C)nn1-c1ccccc1
Answer: e. Cc1ccsc1C(=O)Nc1cc(C(C)(C)C)nn1-c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccsc1C(=O)Nc1cc(C(C)(C)C)nn1-c1ccccc1
Cc1ccsc1C(=O)Nc1cc(C(C)(C)C)nn1-c1ccccc1
[C][C][C][=C][S][C][=Ring1][Branch1][C][=Branch1][C][=O][N][C][=C][C][Branch1][=Branch2][C][Branch1][C][C][Branch1][C][C][C][=N][N][Ring1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1]
N-(5-tert-butyl-2-phenylpyrazol-3-yl)-3-methylthiophene-2-carboxamide