Task: Answer the multiple-choice question.
Question: Which drug has a -11.484\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1ccc(S(=O)(=O)NCCCN2CCOCC2)c2ccccc12
b.) COc1ccc(S(=O)(=O)Cc2ccc(C(=O)N3CCN(c4ccccc4F)CC3)o2)cc1
c.) CCOc1ccc(N2C(=O)c3cccnc3C2Nc2ccc(C)c(C)c2)cc1
d.) NC(=O)C1CCN(c2oc(-c3ccccc3F)nc2S(=O)(=O)c2ccc(Cl)cc2)CC1
e.) O=C(CN1C(=O)/C(=C\c2cccc(Br)c2)Oc2ccccc21)NCC1CCCO1
Answer: c. CCOc1ccc(N2C(=O)c3cccnc3C2Nc2ccc(C)c(C)c2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(N2C(=O)c3cccnc3C2Nc2ccc(C)c(C)c2)cc1
CCOc1ccc(N2C(=O)c3cccnc3C2Nc2ccc(C)c(C)c2)cc1
[C][C][O][C][=C][C][=C][Branch2][Ring1][S][N][C][=Branch1][C][=O][C][=C][C][=C][N][=C][Ring1][=Branch1][C][Ring1][#Branch2][N][C][=C][C][=C][Branch1][C][C][C][Branch1][C][C][=C][Ring1][Branch2][C][=C][Ring2][Ring1][=Branch2]
7-(3,4-dimethylanilino)-6-(4-ethoxyphenyl)-7H-pyrrolo[3,4-b]pyridin-5-one