Problem statement: Answer the MCQ question.
Question: What is the human ether-à-go-go related gene (hERG) inhibition at 1uM of a drug with the SMILES Cn1c(=O)[nH]c(=O)c2c1nc(CN1CCN(c3cccc(Cl)c3)CC1)n2CCN1CCOCC1?
Constraint: You must return none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] 7.706
[b] -10.793
[c] 5.474
[d] -1.097
[e] 8.044
Answer: b. -10.793\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
Cn1c(=O)[nH]c(=O)c2c1nc(CN1CCN(c3cccc(Cl)c3)CC1)n2CCN1CCOCC1
Cn1c(=O)[nH]c(=O)c2c1nc(CN1CCN(c3cccc(Cl)c3)CC1)n2CCN1CCOCC1
[C][N][C][=Branch1][C][=O][NH1][C][=Branch1][C][=O][C][=C][Ring1][Branch2][N][=C][Branch2][Ring1][#Branch1][C][N][C][C][N][Branch1][N][C][=C][C][=C][C][Branch1][C][Cl][=C][Ring1][#Branch1][C][C][Ring1][=N][N][Ring2][Ring1][Ring1][C][C][N][C][C][O][C][C][Ring1][=Branch1]
8-[[4-(3-chlorophenyl)piperazin-1-yl]methyl]-3-methyl-7-(2-morpholin-4-ylethyl)purine-2,6-dione