Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 0.419\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CC(C)c1ccc(-c2nc(N3CCCC3)nc3n[nH]c(N)c23)cc1
b) Cc1ccc(S(=O)(=O)N2CCC(=O)N(C(COCc3cccc(C(F)(F)F)c3)C(C)C)CC2)cc1
c) Cc1cccc(N(C)S(=O)(=O)c2ccc3[nH]cc(C(=O)N4CCOCC4)c(=O)c3c2)c1
d) O=[N+]([O-])c1ncccc1OCc1ccccc1Br
e) CC(C)(C)c1ccc(-c2ncccc2O)cc1.Cl
Answer: b. Cc1ccc(S(=O)(=O)N2CCC(=O)N(C(COCc3cccc(C(F)(F)F)c3)C(C)C)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(S(=O)(=O)N2CCC(=O)N(C(COCc3cccc(C(F)(F)F)c3)C(C)C)CC2)cc1
Cc1ccc(S(=O)(=O)N2CCC(=O)N(C(COCc3cccc(C(F)(F)F)c3)C(C)C)CC2)cc1
[C][C][=C][C][=C][Branch2][Branch1][=Branch1][S][=Branch1][C][=O][=Branch1][C][=O][N][C][C][C][=Branch1][C][=O][N][Branch2][Ring1][#C][C][Branch2][Ring1][=Branch1][C][O][C][C][=C][C][=C][C][Branch1][=Branch2][C][Branch1][C][F][Branch1][C][F][F][=C][Ring1][#Branch2][C][Branch1][C][C][C][C][C][Ring2][Ring1][=Branch2][C][=C][Ring2][Ring2][C]
1-(4-methylphenyl)sulfonyl-4-[3-methyl-1-[[3-(trifluoromethyl)phenyl]methoxy]butan-2-yl]-1,4-diazepan-5-one