Problem statement: Answer the multiple choice question.
Question: Which drug has a -7.846\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) O=C(O)CC(C(=O)OC1CCCCC1)N1CCOCC1
b.) CCOc1ccc(NC(=O)CSc2nnc(C)n2CCCOC)cc1
c.) CCOc1ccccc1C1c2[nH]c3ccccc3c2C[C@H]2C(=O)N(C3CC3)CC(=O)N12
d.) CC(C)(C)C(=O)N1CCC(O)(CS(=O)(=O)Cc2ccc(Cl)cc2)CC1
e.) Cn1c(=O)c2cc(S(=O)(=O)NCCC(=O)N3CC=C(c4ccccc4)CC3)ccc2n(C)c1=O
Answer: e. Cn1c(=O)c2cc(S(=O)(=O)NCCC(=O)N3CC=C(c4ccccc4)CC3)ccc2n(C)c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cn1c(=O)c2cc(S(=O)(=O)NCCC(=O)N3CC=C(c4ccccc4)CC3)ccc2n(C)c1=O
Cn1c(=O)c2cc(S(=O)(=O)NCCC(=O)N3CC=C(c4ccccc4)CC3)ccc2n(C)c1=O
[C][N][C][=Branch1][C][=O][C][=C][C][Branch2][Ring1][P][S][=Branch1][C][=O][=Branch1][C][=O][N][C][C][C][=Branch1][C][=O][N][C][C][=C][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][Ring1][N][=C][C][=C][Ring2][Ring1][#Branch2][N][Branch1][C][C][C][Ring2][Ring1][S][=O]
1,3-dimethyl-2,4-dioxo-N-[3-oxo-3-(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)propyl]quinazoline-6-sulfonamide