Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -1.695\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) Cc1ccc(NC(=O)CCC(=O)OCCCC(F)(F)C(F)(F)F)cc1
b.) CCc1[nH]nc2c1C(c1ccncc1)C(C#N)=C(N)O2
c.) CCN(C(=O)c1cccnc1)c1ccccc1
d.) COc1ccc(N(C(=O)CCl)C(C)(C(=O)Nc2c(C)cccc2C)c2ccccn2)cc1
e.) Cc1ccc(CNC(=O)CC(C)S(=O)(=O)c2ccc3c(c2)NC(=O)C(C)S3)cc1
Answer: e. Cc1ccc(CNC(=O)CC(C)S(=O)(=O)c2ccc3c(c2)NC(=O)C(C)S3)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(CNC(=O)CC(C)S(=O)(=O)c2ccc3c(c2)NC(=O)C(C)S3)cc1
Cc1ccc(CNC(=O)CC(C)S(=O)(=O)c2ccc3c(c2)NC(=O)C(C)S3)cc1
[C][C][=C][C][=C][Branch2][Ring2][=Branch2][C][N][C][=Branch1][C][=O][C][C][Branch1][C][C][S][=Branch1][C][=O][=Branch1][C][=O][C][=C][C][=C][C][=Branch1][Ring2][=C][Ring1][=Branch1][N][C][=Branch1][C][=O][C][Branch1][C][C][S][Ring1][=Branch2][C][=C][Ring2][Ring1][N]
3-[(2-methyl-3-oxo-4H-1,4-benzothiazin-6-yl)sulfonyl]-N-[(4-methylphenyl)methyl]butanamide