Problem statement: Answer the multiple-choice question.
Question: Which compound has a 1.505\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CC(C)Oc1ccc(C(=O)Nc2ccc(N3CCCC3)cc2)cc1
[b] COc1cccc2c1OC[C@@H](CO)[C@H]2N(C)C(=O)Nc1ccc(Cl)cc1Cl
[c] CC(C)c1ccc2oc(=O)cc(CN3CCN(c4ccccc4)CC3)c2c1
[d] C=CCc1cc(C)ccc1OCC(O)CN1CCN(c2ccccc2)CC1
[e] COc1ccc(C(NC(=O)CC(C)C)NC(=O)CC(C)C)cc1OC
Answer: d. C=CCc1cc(C)ccc1OCC(O)CN1CCN(c2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C=CCc1cc(C)ccc1OCC(O)CN1CCN(c2ccccc2)CC1
C=CCc1cc(C)ccc1OCC(O)CN1CCN(c2ccccc2)CC1
[C][=C][C][C][=C][C][Branch1][C][C][=C][C][=C][Ring1][#Branch1][O][C][C][Branch1][C][O][C][N][C][C][N][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][C][C][Ring1][N]
1-(4-methyl-2-prop-2-enylphenoxy)-3-(4-phenylpiperazin-1-yl)propan-2-ol