Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 18.223\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccc(-c2nc(CS(=O)CC(=O)N3CCCC3)c(C)o2)cc1
(b) CC(C)(C)NC(=O)COC(=O)c1cc(Br)ccc1Cl
(c) Cc1cccc(-c2cc3nc(C)cc(NCCCN(C)C)n3n2)c1
(d) COc1ccc(/C=N/n2cc(-c3ccc(OC)cc3)nc2N)cc1
(e) COc1ccc(/C=C2\CN(Cc3ccccc3)C/C(=C\c3ccc(OC)cc3OC)C2=O)c(OC)c1
Answer: e. COc1ccc(/C=C2\CN(Cc3ccccc3)C/C(=C\c3ccc(OC)cc3OC)C2=O)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(/C=C2\CN(Cc3ccccc3)C/C(=C\c3ccc(OC)cc3OC)C2=O)c(OC)c1
COc1ccc(/C=C2\CN(Cc3ccccc3)C/C(=C\c3ccc(OC)cc3OC)C2=O)c(OC)c1
[C][O][C][=C][C][=C][Branch2][Ring2][Branch2][/C][=C][\C][N][Branch1][#Branch2][C][C][=C][C][=C][C][=C][Ring1][=Branch1][C][/C][=Branch1][S][=C][\C][=C][C][=C][Branch1][Ring1][O][C][C][=C][Ring1][Branch2][O][C][C][Ring2][Ring1][Branch2][=O][C][Branch1][Ring1][O][C][=C][Ring2][Ring2][C]
(3E,5E)-1-benzyl-3,5-bis[(2,4-dimethoxyphenyl)methylidene]piperidin-4-one