Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -2.007\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=C(Nc1ccc(N2CCCC2)cc1)c1ccc(Cl)cc1Cl
(b) CCOc1ccc2nc(NCCNC(=O)Nc3cccc(C)c3)c(C#N)cc2c1
(c) O=C(OCCN1C(=O)c2ccccc2C1=O)c1ccccc1
(d) COC(=O)[C@H](C)NC(=O)Nc1ccc(Oc2ccccc2)cc1
(e) NC1=NC[C@H](c2ccccc2)N1CCc1cc(C(F)(F)F)cc(C(F)(F)F)c1
Answer: e. NC1=NC[C@H](c2ccccc2)N1CCc1cc(C(F)(F)F)cc(C(F)(F)F)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
NC1=NC[C@H](c2ccccc2)N1CCc1cc(C(F)(F)F)cc(C(F)(F)F)c1
NC1=NC[C@H](c2ccccc2)N1CCc1cc(C(F)(F)F)cc(C(F)(F)F)c1
[N][C][=N][C][C@H1][Branch1][=Branch2][C][=C][C][=C][C][=C][Ring1][=Branch1][N][Ring1][O][C][C][C][=C][C][Branch1][=Branch2][C][Branch1][C][F][Branch1][C][F][F][=C][C][Branch1][=Branch2][C][Branch1][C][F][Branch1][C][F][F][=C][Ring1][=C]
(5S)-1-[2-[3,5-bis(trifluoromethyl)phenyl]ethyl]-5-phenyl-4,5-dihydroimidazol-2-amine