Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -6.878\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) Cc1cccc(NC(=S)NNC(=O)c2csc(C)c2)c1
b.) COC(=O)c1ccc(NC(=O)C2CCCN(S(=O)(=O)c3cnc[nH]3)C2)cc1
c.) COc1cc2c(=O)n(CCC(=O)NCC3CCCO3)c(=O)n(CC(=O)Nc3ccc(C)cc3C)c2cc1OC
d.) Nc1nnc(SCC(=O)N2CCN(c3ccccc3)CC2)s1
e.) COc1ccccc1NC(=O)c1ccc(NC(=O)CN2CCN(C(=O)c3ccco3)CC2)cc1
Answer: e. COc1ccccc1NC(=O)c1ccc(NC(=O)CN2CCN(C(=O)c3ccco3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1NC(=O)c1ccc(NC(=O)CN2CCN(C(=O)c3ccco3)CC2)cc1
COc1ccccc1NC(=O)c1ccc(NC(=O)CN2CCN(C(=O)c3ccco3)CC2)cc1
[C][O][C][=C][C][=C][C][=C][Ring1][=Branch1][N][C][=Branch1][C][=O][C][=C][C][=C][Branch2][Ring1][N][N][C][=Branch1][C][=O][C][N][C][C][N][Branch1][N][C][=Branch1][C][=O][C][=C][C][=C][O][Ring1][Branch1][C][C][Ring1][=N][C][=C][Ring2][Ring1][#Branch1]
4-[[2-[4-(furan-2-carbonyl)piperazin-1-yl]acetyl]amino]-N-(2-methoxyphenyl)benzamide