Task: Answer the multiple choice question.
Query: Which drug has a 16.066\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a O=C(CN1C(=O)c2ccccc2S1(=O)=O)N1CCN(c2ccccc2)CC1
b Fc1c(F)c(F)c(CSc2nc3ccccc3[nH]2)c(F)c1F
c COC(=O)C(CC(C)C)NC(=O)c1ccc([N+](=O)[O-])cc1
d CCCn1c(SCC(=O)N2CCCCC2)nnc1-c1ccco1
e COc1cc2c(cc1OC)C(CC#N)=NC(C)(C)C2
Answer: e. COc1cc2c(cc1OC)C(CC#N)=NC(C)(C)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(CC#N)=NC(C)(C)C2
COc1cc2c(cc1OC)C(CC#N)=NC(C)(C)C2
2-(6,7-dimethoxy-3,3-dimethyl-4H-isoquinolin-1-yl)acetonitrile