Problem statement: Answer the multiple-choice question.
Query: Which drug has a -2.231\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CC(C)(C)c1ccc(OCC(=O)N/N=C/c2ccsc2)cc1
b) CCOC(=O)C1(Cc2ccccc2C)CCCN(Cc2cc(OC)c(O)c(OC)c2)C1
c) CC(=O)N1CCc2cc(S(=O)(=O)CCC(=O)NCc3cccs3)ccc21
d) CCOc1cc(C2C(C(=O)c3ccc(C)o3)=C(O)C(=O)N2CCc2ccccc2)ccc1O
e) CCCOc1cccc(C(=O)O)c1
Answer: b. CCOC(=O)C1(Cc2ccccc2C)CCCN(Cc2cc(OC)c(O)c(OC)c2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1(Cc2ccccc2C)CCCN(Cc2cc(OC)c(O)c(OC)c2)C1
CCOC(=O)C1(Cc2ccccc2C)CCCN(Cc2cc(OC)c(O)c(OC)c2)C1
ethyl 1-[(4-hydroxy-3,5-dimethoxyphenyl)methyl]-3-[(2-methylphenyl)methyl]piperidine-3-carboxylate