Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 12.250\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C1c2ccccc2C(=O)C1c1ccccn1
b.) O=[N+]([O-])c1ccc(CSc2nnc(Cc3ccccc3)n2-c2ccc(F)cc2)cc1
c.) O=C(O)c1cccc(NC(=S)N/N=C/c2ccccc2OCc2ccc(Br)cc2)c1
d.) O=C(NCC1CCCO1)C1CCN(S(=O)(=O)c2cccc3cccnc23)CC1
e.) CCOC(=O)c1c(N)sc2c(OCC)c(Br)ccc12
Answer: d. O=C(NCC1CCCO1)C1CCN(S(=O)(=O)c2cccc3cccnc23)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCC1CCCO1)C1CCN(S(=O)(=O)c2cccc3cccnc23)CC1
O=C(NCC1CCCO1)C1CCN(S(=O)(=O)c2cccc3cccnc23)CC1
N-(oxolan-2-ylmethyl)-1-quinolin-8-ylsulfonylpiperidine-4-carboxamide