Task: Answer the multiple-choice question.
Question: Which drug exhibits a -10.586\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCN1CCc2c(C#N)c(NCc3ccccc3)nc(N(CC)CC)c2C1
b. CCOC(=O)N1CCN(C(=O)C2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)CC1
c. Cc1cc(NCCO)c2ccccc2n1.Cl
d. CN(C)c1ccc(C(=O)OCC(=O)c2cccs2)cc1
e. CC(C)OC(=O)C1C2C=CC3(CN(Cc4cccs4)C(=O)C13)O2
Answer: b. CCOC(=O)N1CCN(C(=O)C2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(C(=O)C2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)CC1
CCOC(=O)N1CCN(C(=O)C2CCN(S(=O)(=O)c3cc(Cl)ccc3Cl)CC2)CC1
ethyl 4-[1-(2,5-dichlorophenyl)sulfonylpiperidine-4-carbonyl]piperazine-1-carboxylate