Problem statement: Answer the MCQ question.
Question: Which drug has a 14.995\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1ccc(S(=O)(=O)N(C)c2ccc(C(=O)N3CCc4ccccc4C3)cc2)cc1
b. Cn1c(SCC(=O)NCc2cccs2)nnc1-c1ccc(S(=O)(=O)N2CCCC2)cc1
c. COC(=O)C(O)(CC(=O)Nc1ccc(Cl)cc1F)C(F)(F)F
d. CCOC(=O)C1=C(CSc2nc(-c3ccccc3)ccc2C#N)OC(N)=C(C#N)C1c1ccccc1
e. Cc1ccc(SCCNS(C)(=O)=O)cc1
Answer: c. COC(=O)C(O)(CC(=O)Nc1ccc(Cl)cc1F)C(F)(F)F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C(O)(CC(=O)Nc1ccc(Cl)cc1F)C(F)(F)F
COC(=O)C(O)(CC(=O)Nc1ccc(Cl)cc1F)C(F)(F)F
methyl4-(4-chloro-2-fluoroanilino)-2-hydroxy-2-(trifluoromethyl)-4-oxobutanoate