Problem statement: Answer the MCQ question.
Question: Which drug has a -3.675\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CCCCNc1c([N+](=O)[O-])cc(C(=O)O)cc1[N+](=O)[O-]
b. COC(=O)C(O)(CC(=O)Nc1ccc(OC)cc1)C(F)(F)F
c. CN(C)N1C(N)=C(C#N)C(c2cccnc2)C2=C1CC(C)(C)CC2=O
d. CCCCCCCCCc1nc2sc3c(c2c(=O)n1NC(=O)c1ccccc1[N+](=O)[O-])CC(C)(C)OC3
e. Cc1ccc(S(=O)(=O)N2Cc3ccccc3CC2C(=O)Nc2cc(C)on2)cc1
Answer: b. COC(=O)C(O)(CC(=O)Nc1ccc(OC)cc1)C(F)(F)F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C(O)(CC(=O)Nc1ccc(OC)cc1)C(F)(F)F
COC(=O)C(O)(CC(=O)Nc1ccc(OC)cc1)C(F)(F)F
methyl2-hydroxy-4-(4-methoxyanilino)-4-oxo-2-(trifluoromethyl)butanoate