Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 5.212\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCOC(=O)c1c(NC(=O)Cn2nnc3ccccc32)sc2c1CCC(C)C2
(b) Cc1cc(C(C)(C)C)ccc1NC(=O)CC(C)(C)CC(=O)O
(c) COc1ccc(CNC(=O)CCS(=O)(=O)c2ccc3c(c2)NC(=O)C(C)S3)cc1
(d) O=C(NCc1ccc(Cl)cc1)c1cc(S(=O)(=O)N2CCCCC2)c[nH]1
(e) O=C(Nc1nccs1)C1CCN(S(=O)(=O)c2cccnc2)CC1
Answer: e. O=C(Nc1nccs1)C1CCN(S(=O)(=O)c2cccnc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1nccs1)C1CCN(S(=O)(=O)c2cccnc2)CC1
O=C(Nc1nccs1)C1CCN(S(=O)(=O)c2cccnc2)CC1
1-pyridin-3-ylsulfonyl-N-(1,3-thiazol-2-yl)piperidine-4-carboxamide