Problem statement: Answer the multiple-choice question.
Question: Which compound has a -5.478\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. CN1CCN(S(=O)(=O)c2ccc(NC(=O)C(C)(C)C)cc2)CC1
b. COc1cc(CNCCO)ccc1OCC(=O)Nc1ccc(Br)cc1
c. CCOC(=O)C1CCCN(C(=O)Cn2cccc2C(=O)c2ccccc2)C1
d. Cc1ccc(-c2cc(C(=O)NCc3ccco3)no2)cc1
Answer: b. COc1cc(CNCCO)ccc1OCC(=O)Nc1ccc(Br)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(CNCCO)ccc1OCC(=O)Nc1ccc(Br)cc1
COc1cc(CNCCO)ccc1OCC(=O)Nc1ccc(Br)cc1
N-(4-bromophenyl)-2-[4-[(2-hydroxyethylamino)methyl]-2-methoxyphenoxy]acetamide