Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 22.530\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1cc(-c2nn3c(-c4cccnc4)nnc3s2)cc(OC)c1OC
b. Cc1noc(C)c1CSc1ccccc1C(=O)OC(C)C(N)=O
c. COc1ccc(C(CC(=O)N2CCOCC2)c2c(OC)cc(OC)c3ccc(=O)oc23)cc1
d. COc1cccc(NC(=O)CCc2nc(-c3cccs3)no2)c1
e. CN(C)CCCN(C(=O)c1ccc(C(=O)c2ccccc2)cc1)c1nc2cc3c(cc2s1)OCCO3.Cl
Answer: b. Cc1noc(C)c1CSc1ccccc1C(=O)OC(C)C(N)=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1noc(C)c1CSc1ccccc1C(=O)OC(C)C(N)=O
Cc1noc(C)c1CSc1ccccc1C(=O)OC(C)C(N)=O
(1-amino-1-oxopropan-2-yl) 2-[(3,5-dimethyl-1,2-oxazol-4-yl)methylsulfanyl]benzoate