Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 4.674\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1cc(C(=O)OCC(=O)c2cc(C)n(C)c2C)cc(NC(=O)c2ccco2)c1OC
(b) COc1cc(S(=O)(=O)NCC2CCCO2)c(OC)cc1Cl
(c) COc1ccc(S(=O)(=O)N2CCN(c3ccc(C)cc3C)CC2)cc1OC
(d) N#CC1=C(N)C2=CCCC[C@H]2[C@H](c2ccccc2)C1(C#N)C#N
(e) O=C(Nc1nc(-c2ccc3c(c2)OCO3)cs1)c1ccncc1
Answer: c. COc1ccc(S(=O)(=O)N2CCN(c3ccc(C)cc3C)CC2)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)N2CCN(c3ccc(C)cc3C)CC2)cc1OC
COc1ccc(S(=O)(=O)N2CCN(c3ccc(C)cc3C)CC2)cc1OC
1-(3,4-dimethoxyphenyl)sulfonyl-4-(2,4-dimethylphenyl)piperazine