Problem statement: Answer the multiple-choice question.
Question: Which compound has a -7.947\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCOC(=O)C1=C(COC(=O)c2ncc(Cl)c(Cl)c2Cl)NC(=O)NC1C
(b) COc1ccc([C@H]2CC(=O)C=C(c3ccc4c(c3)sc3ccccc34)C2)cc1
(c) C=CCn1c(COc2ccccc2F)nnc1SCC(=O)Nc1cc2oc3ccccc3c2cc1OC
(d) COc1ccccc1NS(=O)(=O)c1cc(NC(=O)c2ccc(Cl)nc2)ccc1Cl
(e) O=C1C(N2CCOCC2)=C(n2nnc3ccccc32)C(=O)c2ccccc21
Answer: a. CCOC(=O)C1=C(COC(=O)c2ncc(Cl)c(Cl)c2Cl)NC(=O)NC1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1=C(COC(=O)c2ncc(Cl)c(Cl)c2Cl)NC(=O)NC1C
CCOC(=O)C1=C(COC(=O)c2ncc(Cl)c(Cl)c2Cl)NC(=O)NC1C
ethyl 4-methyl-2-oxo-6-[(3,4,5-trichloropyridine-2-carbonyl)oxymethyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate