Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a 13.428\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
(a) CCn1c(SCC(=O)NCc2ccccc2)nc2c(c1=O)SC(C)C2
(b) COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccccc1Cl
(c) COc1ccccc1C(=O)COC(=O)c1nc2nc(C)cc(C)n2n1
(d) Cc1cc(C(=O)CN2c3cccc4cccc(c34)S2(=O)=O)c(C)n1C
Answer: b. COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccccc1Cl
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccccc1Cl
COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccccc1Cl
methyl (1R,5S)-8-[2-(2-chlorophenoxy)ethylcarbamoyl]-3-(3-cyanophenyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate