Task: Answer the multiple choice question.
Query: Which compound has a -22.548\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCN1C(=O)[C@@H]2[C@@H](c3ccc(-c4ccc(C(C)=O)cc4)c(OC)c3)N3CCC[C@@]3(C(=O)OC)[C@@H]2C1=O.O=C(O)C(F)(F)F
b. Cc1cc(C)n(CCN(C)Cc2cn(C)nc2-c2ccccc2F)n1
c. COc1ccc(CN2CCN(c3ccccn3)CC2)cc1OCc1ccccc1
d. COCCN1CCN(Cc2nc(C3(c4ccc(C)cc4)CCCC3)no2)CC1
e. COc1ccc(C(C)NC(=O)c2ccncc2)cc1OC
Answer: c. COc1ccc(CN2CCN(c3ccccn3)CC2)cc1OCc1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CN2CCN(c3ccccn3)CC2)cc1OCc1ccccc1
COc1ccc(CN2CCN(c3ccccn3)CC2)cc1OCc1ccccc1
1-[(4-methoxy-3-phenylmethoxyphenyl)methyl]-4-pyridin-2-ylpiperazine