Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -56.478\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. O=C(NCCNC(=O)c1ccccc1Cl)c1ccco1
b. O=C(NCCc1ccccn1)c1cncc(Br)c1
c. O=C(CSc1cccc[n+]1[O-])c1ccc(-c2ccccc2)cc1
d. CCCOc1ccc(N2CC(C(=O)Nc3ccccc3C(=O)NC)CC2=O)cc1
e. CN(C)c1cc(Cl)c2nonc2c1N
Answer: d. CCCOc1ccc(N2CC(C(=O)Nc3ccccc3C(=O)NC)CC2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCOc1ccc(N2CC(C(=O)Nc3ccccc3C(=O)NC)CC2=O)cc1
CCCOc1ccc(N2CC(C(=O)Nc3ccccc3C(=O)NC)CC2=O)cc1
N-[2-(methylcarbamoyl)phenyl]-5-oxo-1-(4-propoxyphenyl)pyrrolidine-3-carboxamide