Task: Answer the multiple-choice question.
Question: Which compound has a 17.268\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CS(=O)(=O)N(CC(=O)NCCSC1CCCCC1)c1cccc(F)c1
b.) CC(=O)Nc1ccc(NC(=O)CSc2ccc(-c3cccnc3)nn2)cc1
c.) CCOc1ccc(S(=O)(=O)NCCC(=O)N2CCN(c3ncccn3)CC2)cc1
d.) O=C(NCCc1ccc(C(F)(F)F)cc1)C1CCC(=O)N(CCCN2CCCC2=O)C1
e.) COc1ccc(/C=C/C(O)=C2/C(=O)N(C)C3(C)CC2c2ccccc2O3)cc1
Answer: d. O=C(NCCc1ccc(C(F)(F)F)cc1)C1CCC(=O)N(CCCN2CCCC2=O)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCCc1ccc(C(F)(F)F)cc1)C1CCC(=O)N(CCCN2CCCC2=O)C1
O=C(NCCc1ccc(C(F)(F)F)cc1)C1CCC(=O)N(CCCN2CCCC2=O)C1
6-oxo-1-[3-(2-oxopyrrolidin-1-yl)propyl]-N-[2-[4-(trifluoromethyl)phenyl]ethyl]piperidine-3-carboxamide