Problem statement: Answer the MCQ question.
Question: Which drug has a 18.699\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CC1CCCC(C)N1C(=O)c1cc(-c2ccc3c(c2)OCO3)on1
(b) C[C@@H]1C=C(C(=O)N2CCN(C)CC2)O[C@H](OCc2ccc(CO)cc2)C1
(c) COc1ccccc1CCNC(=O)CCC(=O)N1CC2C[C@@H](C1)Cn1c2cccc1=O
(d) Cc1noc(C)c1C(=O)N1CCC2(CC1)OCCO2
(e) C=CCN1C=C2C(=O)C(C)(OC(=O)C3CCCC3)C(=O)C(c3ccccc3)=C2C=C1CCCC(=O)OC
Answer: b. C[C@@H]1C=C(C(=O)N2CCN(C)CC2)O[C@H](OCc2ccc(CO)cc2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C[C@@H]1C=C(C(=O)N2CCN(C)CC2)O[C@H](OCc2ccc(CO)cc2)C1
C[C@@H]1C=C(C(=O)N2CCN(C)CC2)O[C@H](OCc2ccc(CO)cc2)C1
[(2S,4S)-2-[[4-(hydroxymethyl)phenyl]methoxy]-4-methyl-3,4-dihydro-2H-pyran-6-yl]-(4-methylpiperazin-1-yl)methanone