Problem statement: Answer the MCQ question.
Question: Which drug has a 12.858\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1cc(C=O)ccc1OCCOCCOc1ccc(Cl)cc1
b) CSc1ccccc1-n1nnnc1SCC(=O)Nc1ccccc1C
c) COc1ccc(C(=O)NCc2nnc(SCC(=O)N3CCCCCC3)o2)cc1OC
d) CCOc1ccc(OCCC(=O)OCC(=O)Nc2cc(OCC)c(N3CCOCC3)cc2OCC)cc1
e) CCNC(=O)C(=O)Nc1ccc2c(c1)N(S(=O)(=O)c1cccs1)CCC2
Answer: d. CCOc1ccc(OCCC(=O)OCC(=O)Nc2cc(OCC)c(N3CCOCC3)cc2OCC)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(OCCC(=O)OCC(=O)Nc2cc(OCC)c(N3CCOCC3)cc2OCC)cc1
CCOc1ccc(OCCC(=O)OCC(=O)Nc2cc(OCC)c(N3CCOCC3)cc2OCC)cc1
[2-(2,5-diethoxy-4-morpholin-4-ylanilino)-2-oxoethyl] 3-(4-ethoxyphenoxy)propanoate