Problem statement: Answer the multiple choice question.
Query: Which drug has a -11.425\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: Cc1ccccc1OCCC(=O)Nc1ccccc1C(=O)NC1CC1
b: O=C(NCC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1)c1ccc2ccccc2c1
c: COc1ccc(CCNC(=O)C2CC3Cn4c(nc5cc(Cl)c(Cl)cc54)C3N2C)cc1
d: Cc1cc(/C=C2\SC(N)=NC2=O)c(C)n1-c1ccc(F)cc1
e: COC(=O)[C@@H](NC(=O)N1CCC(Cc2ccccc2)CC1)C(C)C
Answer: c. COc1ccc(CCNC(=O)C2CC3Cn4c(nc5cc(Cl)c(Cl)cc54)C3N2C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CCNC(=O)C2CC3Cn4c(nc5cc(Cl)c(Cl)cc54)C3N2C)cc1
COc1ccc(CCNC(=O)C2CC3Cn4c(nc5cc(Cl)c(Cl)cc54)C3N2C)cc1
4,5-dichloro-N-[2-(4-methoxyphenyl)ethyl]-11-methyl-1,8,11-triazatetracyclo[7.6.0.02,7.010,14]pentadeca-2,4,6,8-tetraene-12-carboxamide