Problem statement: Answer the MCQ question.
Query: Which compound has a -30.641\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) COc1ccc(C(=O)N/N=C/C23CC[C@@H](O)CC2(O)CC[C@@H]2[C@@H]3CCC3(C)C(C4=CC(=O)OC4)CCC23O)cc1
(b) Cc1cc(/C=C2/NC(=O)NC2=O)c(C)n1C
(c) CCn1ccnc1CN1CCCC(C(=O)c2cc(Cl)ccc2OC)C1
(d) CC(C)c1ccc(OCC(=O)NN2C(=O)c3ccccc3C2=O)c(Br)c1
Answer: c. CCn1ccnc1CN1CCCC(C(=O)c2cc(Cl)ccc2OC)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCn1ccnc1CN1CCCC(C(=O)c2cc(Cl)ccc2OC)C1
CCn1ccnc1CN1CCCC(C(=O)c2cc(Cl)ccc2OC)C1
(5-chloro-2-methoxyphenyl)-[1-[(1-ethylimidazol-2-yl)methyl]piperidin-3-yl]methanone