Problem statement: Answer the MCQ question.
Query: Which compound exhibits a 16.038\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. O=S(=O)(Nc1ncccn1)c1ccc(NC(=S)N2CCN(c3cccc(C(F)(F)F)c3)CC2)cc1
b. O=S(=O)(Nc1ccc(S(=O)(=O)N2CCOCC2)cc1)c1ccc(Br)cc1
c. COc1ccccc1NS(=O)(=O)c1ccc(C(N)=O)cc1
d. CCn1c(=O)cc(OCC(=O)Nc2cccc(C)n2)c2ccccc21
Answer: a. O=S(=O)(Nc1ncccn1)c1ccc(NC(=S)N2CCN(c3cccc(C(F)(F)F)c3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=S(=O)(Nc1ncccn1)c1ccc(NC(=S)N2CCN(c3cccc(C(F)(F)F)c3)CC2)cc1
O=S(=O)(Nc1ncccn1)c1ccc(NC(=S)N2CCN(c3cccc(C(F)(F)F)c3)CC2)cc1
N-[4-(pyrimidin-2-ylsulfamoyl)phenyl]-4-[3-(trifluoromethyl)phenyl]piperazine-1-carbothioamide