Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -2.268\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1ccc(C(CNC(=O)C(=O)Nc2ccc3c(c2)OCO3)N2CCN(C)CC2)cc1
b. COC(=O)c1ccc(CSc2ncnc3c2oc2ccccc23)o1
c. Cc1cccc(OC(=O)N2CCOCC2)c1
d. CCN(CCCCCCN)c1ccc2c(=O)[nH][nH]c(=O)c2c1
e. Cc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)COc1ccc2c(C)cc(=O)oc2c1
Answer: b. COC(=O)c1ccc(CSc2ncnc3c2oc2ccccc23)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(CSc2ncnc3c2oc2ccccc23)o1
COC(=O)c1ccc(CSc2ncnc3c2oc2ccccc23)o1
methyl 5-([1]benzofuro[3,2-d]pyrimidin-4-ylsulfanylmethyl)furan-2-carboxylate