Problem statement: Answer the MCQ question.
Question: Which compound has a 16.167\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. O=C(Nc1nccs1)NC(C(F)(F)F)C(F)(F)F
b. Cc1ccc(OCC(=O)Nc2ccccc2F)cc1
c. COc1ccc(S(=O)(=O)NCC2CCCN(CC(C)(C)C)C2)cc1
d. COc1cccc(C2/C(=C(/O)c3cnn(-c4ccccc4)c3C)C(=O)C(=O)N2CCN(C)C)c1OC
e. COc1ccc(OC)c(CCNC(=O)c2ccc3c(c2)N(Cc2ccccc2)CCS3)c1
Answer: e. COc1ccc(OC)c(CCNC(=O)c2ccc3c(c2)N(Cc2ccccc2)CCS3)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OC)c(CCNC(=O)c2ccc3c(c2)N(Cc2ccccc2)CCS3)c1
COc1ccc(OC)c(CCNC(=O)c2ccc3c(c2)N(Cc2ccccc2)CCS3)c1
4-benzyl-N-[2-(2,5-dimethoxyphenyl)ethyl]-2,3-dihydro-1,4-benzothiazine-6-carboxamide