Problem statement: Answer the multiple-choice question.
Question: Which drug has a 3.388\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] Cc1ccc(Oc2nnc(-c3ccc(C)cc3)c3ccccc23)cc1
[b] COc1ccc(Nc2cc(C)nc(N)n2)cc1
[c] COc1ccc(CNC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1
[d] CCOc1ccc(CCNC(=O)c2ccc(CS(=O)Cc3cccc(Cl)c3)o2)cc1
[e] O=C(Nc1ccccc1SCC1CSc2nc3ccccc3c(=O)n21)c1ccccc1Cl
Answer: c. COc1ccc(CNC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1
COc1ccc(CNC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1
4-(4-fluorophenyl)-N-[(4-methoxyphenyl)methyl]piperazine-1-carboxamide