Problem statement: Answer the MCQ question.
Question: Which drug has a -15.815\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1ccc(NC(=O)C(=O)NCCN2CCN(C(=O)c3ccc(C)cc3)CC2)cc1
b: COc1cccc(CC(=O)NNC(=O)c2c(-c3ccccc3)noc2C)c1
c: CCS(=O)(=O)Nc1cccc(C2=NN(S(C)(=O)=O)C(c3cccs3)C2)c1
d: NC(=O)c1ccc(N2CCOCC2)nc1
e: O=C(Cc1ccccc1)NCCc1cn2ccsc2n1
Answer: b. COc1cccc(CC(=O)NNC(=O)c2c(-c3ccccc3)noc2C)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CC(=O)NNC(=O)c2c(-c3ccccc3)noc2C)c1
COc1cccc(CC(=O)NNC(=O)c2c(-c3ccccc3)noc2C)c1
N'-[2-(3-methoxyphenyl)acetyl]-5-methyl-3-phenyl-1,2-oxazole-4-carbohydrazide