Problem statement: Answer the multiple-choice question.
Question: Which drug has a -45.743\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCOC(=O)c1ccc(N/C(=N\S(=O)(=O)c2ccc(F)cc2F)c2ccccc2)cc1
b. O=C(Nc1ccccc1N1CCCC1)C1CCN(S(=O)(=O)c2ccccc2)CC1
c. N#Cc1ccccc1S(=O)(=O)N1CCC(C(=O)NCc2ccccc2CN2CCCC2)CC1
d. O=C(Nc1nnc(SCC(=O)N2CCCc3ccccc32)s1)c1ccc2ccccc2c1
e. Cc1cc(S(=O)(=O)N2CCOCC2)ccc1OCC(=O)NCc1ccco1
Answer: c. N#Cc1ccccc1S(=O)(=O)N1CCC(C(=O)NCc2ccccc2CN2CCCC2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N#Cc1ccccc1S(=O)(=O)N1CCC(C(=O)NCc2ccccc2CN2CCCC2)CC1
N#Cc1ccccc1S(=O)(=O)N1CCC(C(=O)NCc2ccccc2CN2CCCC2)CC1
1-(2-cyanophenyl)sulfonyl-N-[[2-(pyrrolidin-1-ylmethyl)phenyl]methyl]piperidine-4-carboxamide