Problem statement: Answer the multiple-choice question.
Query: Which compound has a 8.345\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CCCN(CCC)C1CC(=O)N(Cc2ccccc2)C1=O
b O=C(Nc1ccncc1)C1CCN(S(=O)(=O)c2ccccc2C(F)(F)F)CC1
c COC(OC)C(C)NC(=O)NC(=O)c1ccccc1Cl
d Cc1nc2ccccc2c(=O)n1NC(=O)c1ccccc1Br
e CC(=O)c1c(C)[nH]c(C(=O)OC(C)C(=O)Nc2ccc(C)c(S(=O)(=O)N3CCOCC3)c2)c1C
Answer: b. O=C(Nc1ccncc1)C1CCN(S(=O)(=O)c2ccccc2C(F)(F)F)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1ccncc1)C1CCN(S(=O)(=O)c2ccccc2C(F)(F)F)CC1
O=C(Nc1ccncc1)C1CCN(S(=O)(=O)c2ccccc2C(F)(F)F)CC1
N-pyridin-4-yl-1-[2-(trifluoromethyl)phenyl]sulfonylpiperidine-4-carboxamide