Task: Answer the multiple-choice question.
Query: Which drug exhibits a -4.646\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COC(=O)C1=C(C)NC2=C(C(=O)CCC2)C1c1cn(Cc2ccc(Br)cc2)nc1-c1ccccc1
b) COc1cc(C=O)ccc1Oc1nnnn1-c1ccc(C(N)=O)cc1
c) Cc1ccc(C(=O)N2CCCC(CCC(=O)N3CCN(c4ccccn4)CC3)C2)s1
d) CCN(CC)S(=O)(=O)c1ccc2c(c1)N(CC(=O)NCCCN1CC(C)CC(C)C1)C(=O)CO2
e) O=C(NCCc1cccc(C(F)(F)F)c1)C1CCC(=O)N(Cc2ccc(Cl)cc2)C1
Answer: e. O=C(NCCc1cccc(C(F)(F)F)c1)C1CCC(=O)N(Cc2ccc(Cl)cc2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCCc1cccc(C(F)(F)F)c1)C1CCC(=O)N(Cc2ccc(Cl)cc2)C1
O=C(NCCc1cccc(C(F)(F)F)c1)C1CCC(=O)N(Cc2ccc(Cl)cc2)C1
1-[(4-chlorophenyl)methyl]-6-oxo-N-[2-[3-(trifluoromethyl)phenyl]ethyl]piperidine-3-carboxamide