Task: Answer the multiple-choice question.
Question: Which compound has a 8.422\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Cc1cc(Cl)c(S(N)(=O)=O)cc1OCC(=O)NC1CCCCC1
b CC(=O)NCCc1nc2ccccc2n1Cc1ccccc1
c O=c1c(Cc2ccc(F)cc2)c(O)ccn1Cc1cccc(Cl)c1
d O=C1CC2(CCCC2)Oc2ccc(F)cc21
e COc1ccc(OCCSc2nc3ccccc3n2CCC(=O)O)cc1
Answer: c. O=c1c(Cc2ccc(F)cc2)c(O)ccn1Cc1cccc(Cl)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=c1c(Cc2ccc(F)cc2)c(O)ccn1Cc1cccc(Cl)c1
O=c1c(Cc2ccc(F)cc2)c(O)ccn1Cc1cccc(Cl)c1
1-[(3-chlorophenyl)methyl]-3-[(4-fluorophenyl)methyl]-4-hydroxypyridin-2-one