Problem statement: Answer the multiple-choice question.
Query: Which compound has a 11.487\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCC(=O)Nc1ccc(C(=O)NNC(=O)COc2cccc(C)c2)cc1
(b) COCc1[nH]nc2c1C(c1ccccc1F)C(C#N)=C(N)O2
(c) COc1ccc(CCNC(=O)Cc2cccc(C(F)(F)F)c2)cc1OC
(d) C=CCn1c(C)cc(C(=O)CSc2nc(N)cc(N)n2)c1C
(e) CCO.CCOC(=O)C1=C(C)Nc2sc(C(=O)c3ccc(OC)cc3)c(N)c2C1c1ccc(C(=O)OC)cc1
Answer: b. COCc1[nH]nc2c1C(c1ccccc1F)C(C#N)=C(N)O2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCc1[nH]nc2c1C(c1ccccc1F)C(C#N)=C(N)O2
COCc1[nH]nc2c1C(c1ccccc1F)C(C#N)=C(N)O2
6-amino-4-(2-fluorophenyl)-3-(methoxymethyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile