Problem statement: Answer the multiple-choice question.
Query: Which drug has a 2.522\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCO[C@@H]1OC(C(=O)NCc2ccccc2)=C[C@H](C2CC2)[C@H]1CCCO
b) CCOC(=O)c1c(C)nc2sc3c(=O)n(-c4ccc(C(C)=O)cc4)nnc3c2c1-c1ccc(Cl)cc1
c) Cc1cc2c(cc1S(=O)(=O)Nc1ccc(OC(F)(F)F)cc1)OCC(=O)N2
d) O=C(COC(=O)CCc1ccccc1)Nc1cc([N+](=O)[O-])ccc1F
e) Cc1ccc(C(=O)C2CCN(CC(=O)Nc3ccccc3C)CC2)cc1
Answer: a. CCO[C@@H]1OC(C(=O)NCc2ccccc2)=C[C@H](C2CC2)[C@H]1CCCO
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCO[C@@H]1OC(C(=O)NCc2ccccc2)=C[C@H](C2CC2)[C@H]1CCCO
CCO[C@@H]1OC(C(=O)NCc2ccccc2)=C[C@H](C2CC2)[C@H]1CCCO
(2R,3R,4S)-N-benzyl-4-cyclopropyl-2-ethoxy-3-(3-hydroxypropyl)-3,4-dihydro-2H-pyran-6-carboxamide