Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -18.602\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) Nc1nc(Cl)cc(Sc2ccc(F)cc2)n1
(b) Cc1ccc(CC(=O)N2CCOCC2)cc1
(c) COc1ccc(S(=O)(=O)CCC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1
(d) CCOC(=O)c1ccc(NC(=O)CNC(=O)c2ccco2)cc1
(e) COc1ccc(/C=N\N=C(N)N)cc1.O=[N+]([O-])O
Answer: c. COc1ccc(S(=O)(=O)CCC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)CCC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1
COc1ccc(S(=O)(=O)CCC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1
1-[4-(4-fluorophenyl)piperazin-1-yl]-3-(4-methoxyphenyl)sulfonylpropan-1-one