Problem statement: Answer the multiple-choice question.
Question: Which drug has a 5.508\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) Cc1cccc(N2CCN(C(=O)c3ccc4c(c3)NC(=O)C(CSCc3ccc(F)cc3)N4)CC2C)c1
b.) CCOC(=O)c1c(-c2ccc(C)o2)csc1NC(=O)CSc1nncs1
c.) CC(C)c1ccc(OCC(=O)NNC(=S)NC(=O)C2CC2)cc1
d.) O=C(CCc1nc2sc3c(c2c(=O)[nH]1)CCCC3)Nc1ccccc1Cl
e.) COC(=O)CSc1ccc(S(=O)(=O)N2CCOCC2)cc1[N+](=O)[O-]
Answer: a. Cc1cccc(N2CCN(C(=O)c3ccc4c(c3)NC(=O)C(CSCc3ccc(F)cc3)N4)CC2C)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cccc(N2CCN(C(=O)c3ccc4c(c3)NC(=O)C(CSCc3ccc(F)cc3)N4)CC2C)c1
Cc1cccc(N2CCN(C(=O)c3ccc4c(c3)NC(=O)C(CSCc3ccc(F)cc3)N4)CC2C)c1
3-[(4-fluorophenyl)methylsulfanylmethyl]-7-[3-methyl-4-(3-methylphenyl)piperazine-1-carbonyl]-3,4-dihydro-1H-quinoxalin-2-one