Problem statement: Answer the multiple-choice question.
Question: Which drug has a 12.676\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CC(=O)N1CCN(C(=O)CCCNC(=O)c2ccc(Cl)cc2)CC1
[b] CCN(CC)CCCNC(=S)N1CCN(c2nc3ccccc3n2CC)CC1
[c] Cc1c(C)n(CC(O)CN(CCO)CCO)c2ccccc12.Cl
[d] COc1ccc(-n2c(CCC(=O)O)ccc2-c2ccc(F)cc2)c(OC)c1
[e] O=C(N1CCN(c2ccccc2)CC1)C(F)(F)C(F)(F)F
Answer: a. CC(=O)N1CCN(C(=O)CCCNC(=O)c2ccc(Cl)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(=O)N1CCN(C(=O)CCCNC(=O)c2ccc(Cl)cc2)CC1
CC(=O)N1CCN(C(=O)CCCNC(=O)c2ccc(Cl)cc2)CC1
N-[4-(4-acetylpiperazin-1-yl)-4-oxobutyl]-4-chlorobenzamide