Problem statement: Answer the multiple-choice question.
Question: Which drug has a 7.145\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] O=C(CCCn1c(=O)[nH]c2cc(Cl)ccc2c1=O)NCCCN1CCN(c2ccc(F)cc2)CC1
[b] COC(=O)c1ccc(NC(=S)NNC(=O)CC(C)C)cc1
[c] Cc1cccc(NC(=O)NCCN2C(=O)C3C4C=CC(C4)C3C2=O)c1
[d] C#CCOc1c(Br)cc(/C=N\NC(=O)CN2CCOCC2)cc1OCC
[e] COC(=O)C1(CC2CC(c3ccccc3)=NO2)CCN(C(=O)OC(C)(C)C)CC1
Answer: b. COC(=O)c1ccc(NC(=S)NNC(=O)CC(C)C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(NC(=S)NNC(=O)CC(C)C)cc1
COC(=O)c1ccc(NC(=S)NNC(=O)CC(C)C)cc1
methyl4-[(3-methylbutanoylamino)carbamothioylamino]benzoate