Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -9.708\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Cn1c(CO)cnc1SCC(=O)c1ccc(Cl)cc1
b COc1ccc(NC(=O)CSc2nc3[nH]ncc3c(=O)[nH]2)cc1OC
c O=C(O)C/C(=C\c1cc(Br)cs1)c1nc2ccccc2o1
d O=C(Nc1ccc(OC(F)(F)F)cc1)Nc1cccnc1
e Cc1ccc(C(=O)N[C@H](C(=O)OCC(=O)Nc2cccc(S(N)(=O)=O)c2)C(C)C)cc1
Answer: d. O=C(Nc1ccc(OC(F)(F)F)cc1)Nc1cccnc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1ccc(OC(F)(F)F)cc1)Nc1cccnc1
O=C(Nc1ccc(OC(F)(F)F)cc1)Nc1cccnc1
1-pyridin-3-yl-3-[4-(trifluoromethoxy)phenyl]urea