Problem statement: Answer the multiple-choice question.
Question: Which compound has a -14.354\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1cc(C)cc(NC(=O)N2CCN(Cc3ccc4c(c3)OCO4)CC2)c1
b) CC(C)(NO)/C(=N\O)c1ccccc1
c) CC(=O)C(C)n1c(CN2CCN(C(=O)c3ccco3)CC2)nc2c1c(=O)n(C)c(=O)n2C
d) COC(=O)c1nc(NNC(=O)c2ccccc2)sc1-c1ccccc1
e) O=C(Cc1ncc(C(F)(F)F)cc1Cl)N1CCN(c2ccc(F)cc2)CC1
Answer: e. O=C(Cc1ncc(C(F)(F)F)cc1Cl)N1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Cc1ncc(C(F)(F)F)cc1Cl)N1CCN(c2ccc(F)cc2)CC1
O=C(Cc1ncc(C(F)(F)F)cc1Cl)N1CCN(c2ccc(F)cc2)CC1
2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-1-[4-(4-fluorophenyl)piperazin-1-yl]ethanone