Problem statement: Answer the MCQ question.
Question: Which compound exhibits a -6.820\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a: COc1ccc(CCN(C)C(=O)CSc2nc3ncc(Cl)cc3[nH]2)cc1OC
b: O=S(=O)(c1ccccc1Cl)N1CCCC1c1nc(-c2cccc(Cl)c2)no1
c: CCOC(=O)c1c(C)n(C)c2ccc(OCCN(C)C)cc12
d: CCCCn1c(N)c(N(CCOC)C(=O)C2CCN(S(=O)(=O)c3ccccc3)CC2)c(=O)[nH]c1=O
Answer: d. CCCCn1c(N)c(N(CCOC)C(=O)C2CCN(S(=O)(=O)c3ccccc3)CC2)c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCn1c(N)c(N(CCOC)C(=O)C2CCN(S(=O)(=O)c3ccccc3)CC2)c(=O)[nH]c1=O
CCCCn1c(N)c(N(CCOC)C(=O)C2CCN(S(=O)(=O)c3ccccc3)CC2)c(=O)[nH]c1=O
N-(6-amino-1-butyl-2,4-dioxopyrimidin-5-yl)-1-(benzenesulfonyl)-N-(2-methoxyethyl)piperidine-4-carboxamide