Problem statement: Answer the multiple-choice question.
Query: What is the hERG inhibition at 1uM of a compound with the SMILES COC(=O)C1=CN(c2ccc(F)cc2)C=C(C(=O)OC)C1c1ccc(O)cc1?
Constraint: You must return none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: 0.227
b: 1.869
c: 8.289
d: 10.536
e: -4.745
Answer: e. -4.745\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
COC(=O)C1=CN(c2ccc(F)cc2)C=C(C(=O)OC)C1c1ccc(O)cc1
COC(=O)C1=CN(c2ccc(F)cc2)C=C(C(=O)OC)C1c1ccc(O)cc1
dimethyl 1-(4-fluorophenyl)-4-(4-hydroxyphenyl)-4H-pyridine-3,5-dicarboxylate