Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 0.397\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1ccc(-c2oc(=O)n(C)c2-c2ccc(OC)cc2)cc1
b CC(=O)OCCc1[nH]c2ccccc2c1C
c O=c1n(-c2ccccc2)c(=O)n2n1CCCC2
d COC(=O)C1=C(CS(=O)(=O)c2cc(OC)ccc2OC)NC(=O)NC1c1ccc(O)c(OC)c1
e CCOc1ncccc1C(=O)OCC(=O)Nc1c(C)cc(C)cc1C
Answer: d. COC(=O)C1=C(CS(=O)(=O)c2cc(OC)ccc2OC)NC(=O)NC1c1ccc(O)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(CS(=O)(=O)c2cc(OC)ccc2OC)NC(=O)NC1c1ccc(O)c(OC)c1
COC(=O)C1=C(CS(=O)(=O)c2cc(OC)ccc2OC)NC(=O)NC1c1ccc(O)c(OC)c1
methyl 6-[(2,5-dimethoxyphenyl)sulfonylmethyl]-4-(4-hydroxy-3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate