Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 8.810\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] Cc1cc(COc2ccccc2O)on1
[b] CCCCCC(=O)NNC(=O)c1ccc(F)cc1
[c] Cc1ccc(CNC(=O)c2ccc(N3CCC4(CC3)CC(c3ccccc3)=NO4)c(NC(=O)c3ccco3)c2)cc1
[d] Cn1cccc1Cc1nnc(SCC(=O)N2CCCCCC2)n1CCc1ccccc1
[e] CCn1ccnc1CNC(=O)CC1C(=O)NCCN1CC(c1ccccc1)c1ccccc1
Answer: e. CCn1ccnc1CNC(=O)CC1C(=O)NCCN1CC(c1ccccc1)c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCn1ccnc1CNC(=O)CC1C(=O)NCCN1CC(c1ccccc1)c1ccccc1
CCn1ccnc1CNC(=O)CC1C(=O)NCCN1CC(c1ccccc1)c1ccccc1
2-[1-(2,2-diphenylethyl)-3-oxopiperazin-2-yl]-N-[(1-ethylimidazol-2-yl)methyl]acetamide