Problem statement: Answer the MCQ question.
Question: Which compound has a -4.116\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CCOC(=O)c1snc(C(=O)NC2CCCCC2)c1N
[b] CN(C)C(=O)Cn1c(SCC(=O)NC2CCCCC2)nc2ccccc21
[c] O=C(COC(=O)[C@@H]1CC(O)CN1S(=O)(=O)c1ccc(Cl)cc1)NC1CCCCCC1
[d] COCCNC(=O)C(c1cccs1)N(C(=O)Cn1nnc2ccccc21)c1ccc2c(c1)OCO2
[e] CCN1C(=O)c2ccccc2S(=O)(=O)c2ccc(C(=O)NCc3cccnc3)cc21
Answer: d. COCCNC(=O)C(c1cccs1)N(C(=O)Cn1nnc2ccccc21)c1ccc2c(c1)OCO2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCNC(=O)C(c1cccs1)N(C(=O)Cn1nnc2ccccc21)c1ccc2c(c1)OCO2
COCCNC(=O)C(c1cccs1)N(C(=O)Cn1nnc2ccccc21)c1ccc2c(c1)OCO2
2-[1,3-benzodioxol-5-yl-[2-(benzotriazol-1-yl)acetyl]amino]-N-(2-methoxyethyl)-2-thiophen-2-ylacetamide