Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 20.362\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) Cc1cccc(CN2CCC(C(=O)Nc3cccc(-c4cccc(F)c4)c3)CC2)n1
(b) CCOc1ccc(NC(=O)CCN2CCN(c3ccccc3F)CC2)cc1
(c) COc1ccc(CCNC(=O)COC(=O)CCC(=O)c2ccc(F)cc2)cc1OC
(d) CCCCCCCCCNC(=O)[C@H](NC(=O)COc1ccccc1)[C@@H]1NC(C(=O)OC)C(C)(C)S1
Answer: d. CCCCCCCCCNC(=O)[C@H](NC(=O)COc1ccccc1)[C@@H]1NC(C(=O)OC)C(C)(C)S1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCCCCCCNC(=O)[C@H](NC(=O)COc1ccccc1)[C@@H]1NC(C(=O)OC)C(C)(C)S1
CCCCCCCCCNC(=O)[C@H](NC(=O)COc1ccccc1)[C@@H]1NC(C(=O)OC)C(C)(C)S1
methyl (2R)-5,5-dimethyl-2-[(1S)-2-(nonylamino)-2-oxo-1-[(2-phenoxyacetyl)amino]ethyl]-1,3-thiazolidine-4-carboxylate