Problem statement: Answer the multiple-choice question.
Query: Which compound has a -11.999\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C(O)c1ccc(NS(=O)(=O)c2ccc(N3CCCC3)c([N+](=O)[O-])c2)cc1
b) O=C(Nc1ccc2c(c1)CCC2)c1cc(S(=O)(=O)N2CCN(c3ccccc3)CC2)ccc1Cl
c) Oc1cccc2ccc(/C=C/c3cccs3)nc12
d) Cc1ccc2c(c1)C1CN(C)CCC1N2C(=S)Nc1cccnc1
e) CCOc1ccccc1N(CC(=O)NC1CCCCC1)C(=O)CCC(=O)Nc1nccs1
Answer: e. CCOc1ccccc1N(CC(=O)NC1CCCCC1)C(=O)CCC(=O)Nc1nccs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccccc1N(CC(=O)NC1CCCCC1)C(=O)CCC(=O)Nc1nccs1
CCOc1ccccc1N(CC(=O)NC1CCCCC1)C(=O)CCC(=O)Nc1nccs1
N'-[2-(cyclohexylamino)-2-oxoethyl]-N'-(2-ethoxyphenyl)-N-(1,3-thiazol-2-yl)butanediamide