Problem statement: Answer the multiple choice question.
Query: Which drug has a 21.781\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C(c1ccc2c(c1)OCO2)N1CCN(c2ncccn2)CC1
b. O=C(Cc1cccc(NC(=O)C2CCCN(C(=O)CCc3ccccc3)C2)c1)Nc1cccc(C(=O)N2CCCC2)c1
c. COc1cccc(NC(=O)c2ccn(C)n2)c1
d. Cc1cc(OC(=O)c2cc(F)c(F)cc2Cl)nc(C)n1
e. NS(=O)(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2)cc1
Answer: d. Cc1cc(OC(=O)c2cc(F)c(F)cc2Cl)nc(C)n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cc(OC(=O)c2cc(F)c(F)cc2Cl)nc(C)n1
Cc1cc(OC(=O)c2cc(F)c(F)cc2Cl)nc(C)n1
(2,6-dimethylpyrimidin-4-yl) 2-chloro-4,5-difluorobenzoate