Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a -11.652\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1nc2c(-c3ccccc3)c(C)nn2c(C)c1CCC(=O)N1CCOCC1
b) CCOc1ccc(N(CC(=O)Nc2ccc(C)cc2)S(C)(=O)=O)cc1
c) CCOC(=O)N1CCN(C(=O)C2CCN(S(=O)(=O)c3cc(Cl)ccc3OCC)CC2)CC1
d) CC1CCC2(CC1)NC(=O)N(CC(=O)Nc1ccccc1-c1ccccc1)C2=O
e) O=C(CN(C(=O)CCC(=O)Nc1nccs1)c1ccc2c(c1)OCO2)NCc1ccccc1
Answer: c. CCOC(=O)N1CCN(C(=O)C2CCN(S(=O)(=O)c3cc(Cl)ccc3OCC)CC2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(C(=O)C2CCN(S(=O)(=O)c3cc(Cl)ccc3OCC)CC2)CC1
CCOC(=O)N1CCN(C(=O)C2CCN(S(=O)(=O)c3cc(Cl)ccc3OCC)CC2)CC1
ethyl 4-[1-(5-chloro-2-ethoxyphenyl)sulfonylpiperidine-4-carbonyl]piperazine-1-carboxylate