Problem statement: Answer the MCQ question.
Question: Which drug has a 10.820\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CC(=O)Nc1ccc(NC(=O)C2CCCN2C(=O)Nc2ccc(F)cc2)cc1
b. CCCCn1c(N)c(N(Cc2ccccc2OC)C(=O)COc2cc(C)ccc2Cl)c(=O)[nH]c1=O
c. Cc1cc(N2C(=O)c3ccccc3C2=O)n(C)n1
d. CN(C)C(=O)CS(=O)(=O)c1ccc(Cl)cc1
e. CCN1CCN(C(CNS(=O)(=O)c2ccc(OC)c(C)c2)c2cccnc2)CC1
Answer: b. CCCCn1c(N)c(N(Cc2ccccc2OC)C(=O)COc2cc(C)ccc2Cl)c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCn1c(N)c(N(Cc2ccccc2OC)C(=O)COc2cc(C)ccc2Cl)c(=O)[nH]c1=O
CCCCn1c(N)c(N(Cc2ccccc2OC)C(=O)COc2cc(C)ccc2Cl)c(=O)[nH]c1=O
N-(6-amino-1-butyl-2,4-dioxopyrimidin-5-yl)-2-(2-chloro-5-methylphenoxy)-N-[(2-methoxyphenyl)methyl]acetamide