Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -10.675\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1ccc(OCc2nc(C#N)c(NCCCn3ccnc3)o2)cc1
b) O=S(=O)(c1ccc(Cl)cc1)N1CCN=C1SCc1cccc(Cl)c1
c) CCOC(=O)C(=O)C1=C(N2CCOCC2)/C(=C\c2ccc(F)cc2)CC1
d) O=C(CN1C(=O)NC2(CCCC2)C1=O)OCc1ccc(Cl)c(Cl)c1
e) CC(C)Cn1cnc2c(c1=N)C(c1ccccc1)C1=C(CC(C)(C)CC1=O)O2
Answer: e. CC(C)Cn1cnc2c(c1=N)C(c1ccccc1)C1=C(CC(C)(C)CC1=O)O2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)Cn1cnc2c(c1=N)C(c1ccccc1)C1=C(CC(C)(C)CC1=O)O2
CC(C)Cn1cnc2c(c1=N)C(c1ccccc1)C1=C(CC(C)(C)CC1=O)O2
4-imino-8,8-dimethyl-3-(2-methylpropyl)-5-phenyl-7,9-dihydro-5H-chromeno[2,3-d]pyrimidin-6-one