Problem statement: Answer the multiple-choice question.
Question: Which drug has a -5.185\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: Cc1ccc(NC(=O)c2cc3c(CO)cnc(C)c3oc2=Nc2cccc(C(N)=O)c2)cc1
b: CC(C)CNC(=O)C1CCN(c2ccc(S(=O)(=O)N3CCOCC3)cc2[N+](=O)[O-])CC1
c: CCS(=O)c1ccccc1C(=O)OC(C)C(=O)Nc1ccc(S(=O)(=O)N2CCCC2)cc1
d: Cc1csc(NC(=S)NC(=O)c2ccccc2)n1
e: CC(C)Sc1nc(N2CCOCC2)c2c(c1C#N)CC(C)(C)N(C)C2
Answer: e. CC(C)Sc1nc(N2CCOCC2)c2c(c1C#N)CC(C)(C)N(C)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)Sc1nc(N2CCOCC2)c2c(c1C#N)CC(C)(C)N(C)C2
CC(C)Sc1nc(N2CCOCC2)c2c(c1C#N)CC(C)(C)N(C)C2
6,6,7-trimethyl-1-morpholin-4-yl-3-propan-2-ylsulfanyl-5,8-dihydro-2,7-naphthyridine-4-carbonitrile