Problem statement: Answer the multiple-choice question.
Question: Which compound has a 3.864\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. O=C(NCCNC(=O)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F)Nc1ccccc1
b. CCOC(=O)c1cc(C#N)c(N2CCNCC2)nc1C(F)(F)F
c. CN(Cc1nccn1C)C(=O)CC1C(=O)NCCN1CC(c1ccccc1)c1ccccc1
d. CCn1c(CNC(=O)C23CC4CC(CC(C4)C2)C3)nnc1SCC(=O)Nc1nnc(C)s1
Answer: c. CN(Cc1nccn1C)C(=O)CC1C(=O)NCCN1CC(c1ccccc1)c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(Cc1nccn1C)C(=O)CC1C(=O)NCCN1CC(c1ccccc1)c1ccccc1
CN(Cc1nccn1C)C(=O)CC1C(=O)NCCN1CC(c1ccccc1)c1ccccc1
2-[1-(2,2-diphenylethyl)-3-oxopiperazin-2-yl]-N-methyl-N-[(1-methylimidazol-2-yl)methyl]acetamide