Task: Answer the multiple-choice question.
Query: Which compound has a -10.172\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a CC(=O)Nc1ccc(N=Cc2c(O)ccc3ccccc23)cc1
b COc1ccc(-c2noc(CCCC(=O)NC3CCCC3)n2)cc1
c Cc1ccccc1OCC(=O)NC(=S)Nc1ccccc1N1CCN(S(C)(=O)=O)CC1
d COc1ccc2[nH]c3c(c2c1)CCN1C(=O)N([C@@H](C)C(=O)NC2CCN(Cc4ccccc4)CC2)C(=O)[C@]31C
Answer: d. COc1ccc2[nH]c3c(c2c1)CCN1C(=O)N([C@@H](C)C(=O)NC2CCN(Cc4ccccc4)CC2)C(=O)[C@]31C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2[nH]c3c(c2c1)CCN1C(=O)N([C@@H](C)C(=O)NC2CCN(Cc4ccccc4)CC2)C(=O)[C@]31C
COc1ccc2[nH]c3c(c2c1)CCN1C(=O)N([C@@H](C)C(=O)NC2CCN(Cc4ccccc4)CC2)C(=O)[C@]31C
(2S)-N-(1-benzylpiperidin-4-yl)-2-[(2S)-12-methoxy-2-methyl-3,5-dioxo-4,6,16-triazatetracyclo[7.7.0.02,6.010,15]hexadeca-1(9),10(15),11,13-tetraen-4-yl]propanamide