Problem statement: Answer the MCQ question.
Question: Which drug has a -3.303\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1cccc(C(=O)NCCC(=O)NCc2ccccc2Cl)c1
b) O=C(Nc1ccc2nn(-c3ccccc3)nc2c1)c1ccco1
c) O=C(NNC(=O)c1ccc(-c2ccccc2)cc1)Nc1ccccc1F
d) O=C(COC(=O)c1cc(Br)ccc1O)Nc1ccc2c(c1)OCO2
e) O=C(c1ccco1)N1CCN(C(=O)c2snc3ccc(Cl)cc23)CC1
Answer: e. O=C(c1ccco1)N1CCN(C(=O)c2snc3ccc(Cl)cc23)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccco1)N1CCN(C(=O)c2snc3ccc(Cl)cc23)CC1
O=C(c1ccco1)N1CCN(C(=O)c2snc3ccc(Cl)cc23)CC1
[4-(5-chloro-2,1-benzothiazole-3-carbonyl)piperazin-1-yl]-(furan-2-yl)methanone