Problem statement: Answer the multiple choice question.
Question: Which drug has a -82.449\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CCOC(=O)C1(CCOc2ccccc2)CCN(Cc2ccc(OCC)c(CO)c2)CC1
b O=C1Nc2ccc(Br)cc2/C1=C/C(=O)c1ccc2c(c1)OCO2
c Cl.Clc1ccc(CSc2nnc([C@@H]3CCCN3)o2)cc1
d COc1cc(-c2nc(CCNC(=O)c3ccco3)cs2)cc(OC)c1OC
e CCc1noc(C)c1C(=O)NCCc1ccc(S(N)(=O)=O)cc1
Answer: a. CCOC(=O)C1(CCOc2ccccc2)CCN(Cc2ccc(OCC)c(CO)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1(CCOc2ccccc2)CCN(Cc2ccc(OCC)c(CO)c2)CC1
CCOC(=O)C1(CCOc2ccccc2)CCN(Cc2ccc(OCC)c(CO)c2)CC1
ethyl 1-[[4-ethoxy-3-(hydroxymethyl)phenyl]methyl]-4-(2-phenoxyethyl)piperidine-4-carboxylate