Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 2.480\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. C=CCSc1nc(C)c(CCCC)c(=O)[nH]1
b. FC(F)(F)c1cc(-c2cccs2)n[nH]1
c. COc1ccc(S(=O)(=O)N(C)c2ccc(OC(=O)C(C)Oc3ccc(F)cc3)cc2)cc1
d. Cc1cc(C)nc(Nc2n[nH]c(-c3cccc4ccccc34)n2)n1
e. CSc1cccc(CN2CCC(n3nccc3NC(=O)C3CC3)CC2)c1
Answer: c. COc1ccc(S(=O)(=O)N(C)c2ccc(OC(=O)C(C)Oc3ccc(F)cc3)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)N(C)c2ccc(OC(=O)C(C)Oc3ccc(F)cc3)cc2)cc1
COc1ccc(S(=O)(=O)N(C)c2ccc(OC(=O)C(C)Oc3ccc(F)cc3)cc2)cc1
[4-[(4-methoxyphenyl)sulfonyl-methylamino]phenyl]2-(4-fluorophenoxy)propanoate