Problem statement: Answer the multiple-choice question.
Question: Which compound has a 17.131\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCOc1ncccc1C(=O)OCC(=O)N1c2ccccc2CC1C
(b) CC1=C(C(=O)N2CCOCC2)C(c2cc(C)cs2)NC(=O)N1
(c) COc1cc2c(cc1OC)CN(C(=O)CCOc1ccccc1C)CC2
(d) O=C(Nc1cccc(F)c1)N1CCC(c2ccccc2)CC1
(e) CSc1nn2cc(CCN3CCOCC3)c(-c3ccc(F)cc3)nc2c1C#N
Answer: c. COc1cc2c(cc1OC)CN(C(=O)CCOc1ccccc1C)CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)CN(C(=O)CCOc1ccccc1C)CC2
COc1cc2c(cc1OC)CN(C(=O)CCOc1ccccc1C)CC2
1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(2-methylphenoxy)propan-1-one