Task: Answer the multiple-choice question.
Query: Which drug has a 4.370\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1cccc(CC(=O)N2CCC(CCC(=O)Nc3cccc(OC)c3)CC2)c1
b) CC(=O)Nc1c(C#N)c(C(C)(C)C)cn1C
c) O=P(c1cccs1)(c1cccs1)c1cccs1
d) Cc1c(NC(=O)C2CCCN2S(=O)(=O)c2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C
e) CCOC(=O)c1[nH]ncc1[C@@H]1C[C@H]2CN(Cc3cccc(Cl)c3)C(=O)[C@]23CCCN13
Answer: e. CCOC(=O)c1[nH]ncc1[C@@H]1C[C@H]2CN(Cc3cccc(Cl)c3)C(=O)[C@]23CCCN13
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)c1[nH]ncc1[C@@H]1C[C@H]2CN(Cc3cccc(Cl)c3)C(=O)[C@]23CCCN13
CCOC(=O)c1[nH]ncc1[C@@H]1C[C@H]2CN(Cc3cccc(Cl)c3)C(=O)[C@]23CCCN13
ethyl4-[(1S,5S,7S)-3-[(3-chlorophenyl)methyl]-2-oxo-3,8-diazatricyclo[6.3.0.01,5]undecan-7-yl]-1H-pyrazole-5-carboxylate