Problem statement: Answer the multiple-choice question.
Query: Which drug has a 2.430\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a: Cl.c1csc(COc2ccccc2CNC2CCCCC2)c1
b: COC(=O)C(NC(=O)CCc1nnc2ccc(N3CCCCC3)nn12)C(C)C
c: COC(=O)[C@]1(CC(C)C)N[C@H](c2ccc(-c3ccc(F)cc3)c(OC)c2)[C@@H]2C(=O)N(C)C(=O)[C@@H]21.O=C(O)C(F)(F)F
d: COc1cccc(C(=O)Nc2nc(-c3ccccc3)c(-c3ccccc3)o2)c1
Answer: c. COC(=O)[C@]1(CC(C)C)N[C@H](c2ccc(-c3ccc(F)cc3)c(OC)c2)[C@@H]2C(=O)N(C)C(=O)[C@@H]21.O=C(O)C(F)(F)F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)[C@]1(CC(C)C)N[C@H](c2ccc(-c3ccc(F)cc3)c(OC)c2)[C@@H]2C(=O)N(C)C(=O)[C@@H]21.O=C(O)C(F)(F)F
COC(=O)[C@]1(CC(C)C)N[C@H](c2ccc(-c3ccc(F)cc3)c(OC)c2)[C@@H]2C(=O)N(C)C(=O)[C@@H]21.O=C(O)C(F)(F)F
methyl (1S,3R,3aS,6aR)-1-[4-(4-fluorophenyl)-3-methoxyphenyl]-5-methyl-3-(2-methylpropyl)-4,6-dioxo-1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3-carboxylate;2,2,2-trifluoroacetic acid