Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 5.813\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COC(=O)C1(C)NC(c2ccc(C)cc2)C2C(=O)N(c3ccc(F)cc3)C(=O)C21
b.) O=C(/C=C/c1ccc(Cl)cc1)N1CCOCC1
c.) CCc1ccc(NC(=O)c2c(C(=O)Nc3ccccc3)sc3nc(C)cc(=O)n23)cc1
d.) O=C(NC1CCSc2ccccc21)c1cccc(OC(F)F)c1
e.) C[C@H](NC(=O)c1nc[nH]c1C(=O)NC1CC[NH2+]CC1)C(=O)OC(C)(C)C.[Cl-]
Answer: a. COC(=O)C1(C)NC(c2ccc(C)cc2)C2C(=O)N(c3ccc(F)cc3)C(=O)C21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1(C)NC(c2ccc(C)cc2)C2C(=O)N(c3ccc(F)cc3)C(=O)C21
COC(=O)C1(C)NC(c2ccc(C)cc2)C2C(=O)N(c3ccc(F)cc3)C(=O)C21
methyl 5-(4-fluorophenyl)-3-methyl-1-(4-methylphenyl)-4,6-dioxo-1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3-carboxylate