Task: Answer the multiple-choice question.
Query: Which drug exhibits a -11.425\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. Cc1ccc(Cn2ccc(NC(=O)c3cc(C4CC4)on3)n2)cc1
b. COc1ccc(C(CC(=O)c2ccc(C)cc2)C(C#N)C#N)cc1OC
c. O=C(C1CC(=O)N(C2CCCC2)C1)N1CCN(c2ccccc2F)CC1
d. COc1ccccc1CNC(=O)C1CCCCN1S(=O)(=O)c1ccccc1
Answer: d. COc1ccccc1CNC(=O)C1CCCCN1S(=O)(=O)c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1CNC(=O)C1CCCCN1S(=O)(=O)c1ccccc1
COc1ccccc1CNC(=O)C1CCCCN1S(=O)(=O)c1ccccc1
1-(benzenesulfonyl)-N-[(2-methoxyphenyl)methyl]piperidine-2-carboxamide