Problem statement: Answer the MCQ question.
Query: Which drug has a -21.360\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] O=C(CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)N1CCN(C/C=C/c2ccccc2)CC1
[b] COc1ccc(CNc2ccc(S(=O)(=O)N3CCN(C)CC3)cn2)cc1OC
[c] O=C(CSc1nc2c(c(=O)n1-c1ccc(F)cc1)SCC2)NCC1CCCO1
[d] Cc1ccc(NC(=O)C2(c3ccccc3)CCCC2)nc1
[e] CC(C)C[C@H]1COCCS(=O)(=O)N1Cc1cccc(Cl)c1
Answer: a. O=C(CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)N1CCN(C/C=C/c2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)N1CCN(C/C=C/c2ccccc2)CC1
O=C(CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1)N1CCN(C/C=C/c2ccccc2)CC1
N-[3-oxo-3-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]propyl]-4-(trifluoromethoxy)benzenesulfonamide