Problem statement: Answer the multiple choice question.
Question: Which compound has a 15.594\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Cc1cccc(CSc2nc3c(c(=O)[nH]2)CCC3)c1
b COc1ccc(CCC(C)NCCc2ccc(Cl)cc2Cl)cc1
c CCOc1ccc(/C=N/NC(=O)CC(=O)NCc2ccccc2)cc1
d COC(=O)C1=C(c2c(C)noc2C)C[C@@H]2CC[C@H]1N2C(=O)NCC1CC1
e CCOC(=O)N1CCC(N2C(=O)c3ccc(C(=O)Nc4ccc(OC)cc4)cc3C2=O)CC1
Answer: d. COC(=O)C1=C(c2c(C)noc2C)C[C@@H]2CC[C@H]1N2C(=O)NCC1CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2c(C)noc2C)C[C@@H]2CC[C@H]1N2C(=O)NCC1CC1
COC(=O)C1=C(c2c(C)noc2C)C[C@@H]2CC[C@H]1N2C(=O)NCC1CC1
methyl (1R,5S)-8-(cyclopropylmethylcarbamoyl)-3-(3,5-dimethyl-1,2-oxazol-4-yl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate