Problem statement: Answer the multiple-choice question.
Query: Which compound has a -9.328\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1ccc(S(=O)(=O)N2CC=C(C(=O)NCc3ccccc3)CC2)cc1
b. O=C(NC1=NCCS1)c1ccc([N+](=O)[O-])cc1Cl
c. COc1ccc(S(=O)(=O)Nc2ccc3c(c2)OCCO3)cc1OC
d. CC1Cc2ccccc2N1C(=O)C12CCC(C)(C(=O)C1)C2(C)C
e. COc1ccc2c(c1)[nH]c1c(=O)n(Cc3ccncc3)cnc12
Answer: e. COc1ccc2c(c1)[nH]c1c(=O)n(Cc3ccncc3)cnc12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2c(c1)[nH]c1c(=O)n(Cc3ccncc3)cnc12
COc1ccc2c(c1)[nH]c1c(=O)n(Cc3ccncc3)cnc12
7-methoxy-3-(pyridin-4-ylmethyl)-5H-pyrimido[5,4-b]indol-4-one