Problem statement: Answer the multiple-choice question.
Question: Which compound has a 16.840\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CC(=O)c1ccc2c(c1)C1C=CCC1C(c1cc3c(cc1Br)OCO3)N2
(b) COc1cc(/C=C(/C#N)C(=O)Nc2ccc(Cl)cc2)ccc1Oc1nc(Cl)ncc1F
(c) CN1Cc2cccnc2N(C)Cc2cc(Cl)ccc21
(d) COc1ccc(NC(=O)/C(C#N)=C\c2ccc(Br)o2)cc1
(e) Cc1oc(S(=O)(=O)N(C)C)cc1C(=O)Nc1ccc(F)cc1
Answer: b. COc1cc(/C=C(/C#N)C(=O)Nc2ccc(Cl)cc2)ccc1Oc1nc(Cl)ncc1F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(/C=C(/C#N)C(=O)Nc2ccc(Cl)cc2)ccc1Oc1nc(Cl)ncc1F
COc1cc(/C=C(/C#N)C(=O)Nc2ccc(Cl)cc2)ccc1Oc1nc(Cl)ncc1F
(Z)-3-[4-(2-chloro-5-fluoropyrimidin-4-yl)oxy-5-methoxyphenyl]-N-(4-chlorophenyl)-2-cyanoprop-2-enamide