Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 1.542\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc2cc(CN(Cc3ccco3)Cc3nnnn3C3CCCCC3)c(=O)[nH]c2c1
(b) Cc1ccc(-c2cc(Cc3ccncc3)c(=O)[nH]n2)cc1
(c) Cc1ccc(S(=O)(=O)CC(=O)Nc2nc(C(C)(C)C)cs2)cc1
(d) N#CCCN(Cc1cccnc1)S(=O)(=O)c1ccc(S(=O)(=O)N2CCCCCC2)cc1
(e) COc1ccccc1NC(=O)CN(Cc1ccco1)C(=O)c1cccs1
Answer: d. N#CCCN(Cc1cccnc1)S(=O)(=O)c1ccc(S(=O)(=O)N2CCCCCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N#CCCN(Cc1cccnc1)S(=O)(=O)c1ccc(S(=O)(=O)N2CCCCCC2)cc1
N#CCCN(Cc1cccnc1)S(=O)(=O)c1ccc(S(=O)(=O)N2CCCCCC2)cc1
4-(azepan-1-ylsulfonyl)-N-(2-cyanoethyl)-N-(pyridin-3-ylmethyl)benzenesulfonamide