Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 4.374\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. Cc1ccccc1C(=O)NCCNc1ccc([N+](=O)[O-])cc1
b. CCOC(=O)c1c(NC(=O)Cn2nc(C(F)(F)F)cc2C)sc2c1CCC2
c. COC(=O)c1cc(=O)n(CCc2ccc(OC)c(OC)c2)c(=Nc2ccc(F)c(Cl)c2)s1
d. CCCCN(C)CC(O)Cn1cc(/C=C/C(=O)c2ccc(C)cc2)c2ccccc21
Answer: c. COC(=O)c1cc(=O)n(CCc2ccc(OC)c(OC)c2)c(=Nc2ccc(F)c(Cl)c2)s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1cc(=O)n(CCc2ccc(OC)c(OC)c2)c(=Nc2ccc(F)c(Cl)c2)s1
COC(=O)c1cc(=O)n(CCc2ccc(OC)c(OC)c2)c(=Nc2ccc(F)c(Cl)c2)s1
methyl 2-(3-chloro-4-fluorophenyl)imino-3-[2-(3,4-dimethoxyphenyl)ethyl]-4-oxo-1,3-thiazine-6-carboxylate