Problem statement: Answer the MCQ question.
Question: Which drug has a 10.089\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a.) COc1ccc(NC(=O)c2ccc(NC3=NC4CS(=O)(=O)CC4S3)cc2)cc1
b.) O=C(NNc1ccc(F)cc1)c1c(F)cccc1Cl
c.) COC(=O)c1cc2ccsc2n1CC(=O)N(C)c1ccccc1
d.) COc1ccc(OC)c(C2C(C#N)=C(N)N(N(C)C)C3=C2C(=O)CC(C)(C)C3)c1
Answer: d. COc1ccc(OC)c(C2C(C#N)=C(N)N(N(C)C)C3=C2C(=O)CC(C)(C)C3)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OC)c(C2C(C#N)=C(N)N(N(C)C)C3=C2C(=O)CC(C)(C)C3)c1
COc1ccc(OC)c(C2C(C#N)=C(N)N(N(C)C)C3=C2C(=O)CC(C)(C)C3)c1
2-amino-4-(2,5-dimethoxyphenyl)-1-(dimethylamino)-7,7-dimethyl-5-oxo-6,8-dihydro-4H-quinoline-3-carbonitrile