Task: Answer the multiple-choice question.
Question: Which drug has a 4.963\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) Nc1ccc(Sc2ccccc2CC(=O)O)cc1
b.) CCOP(=O)(OCC)c1cc(C)c(O)c(C(C)(C)C)c1
c.) CCOc1ccc(OCC)c(NC(=O)C2CCN(S(=O)(=O)c3ccc4c(c3)CC(C)N4C(C)=O)CC2)c1
d.) CC(=O)c1c(C)nc(-c2ccc(Cl)cc2)nc1N=CN(C)C
e.) COc1ccc(S(=O)(=O)N2CCOC23CCN(S(=O)(=O)c2cc(C)ccc2C)CC3)cc1
Answer: e. COc1ccc(S(=O)(=O)N2CCOC23CCN(S(=O)(=O)c2cc(C)ccc2C)CC3)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)N2CCOC23CCN(S(=O)(=O)c2cc(C)ccc2C)CC3)cc1
COc1ccc(S(=O)(=O)N2CCOC23CCN(S(=O)(=O)c2cc(C)ccc2C)CC3)cc1
8-(2,5-dimethylphenyl)sulfonyl-4-(4-methoxyphenyl)sulfonyl-1-oxa-4,8-diazaspiro[4.5]decane