Problem statement: Answer the multiple-choice question.
Query: Which drug has a 4.227\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1ccc(C)cc1S(=O)(=O)Nc1cc2c3c(c1)C(C)C(=O)N3CCC2
[b] OC(COc1ccc(CNCCc2ccc(C(F)(F)F)cc2)cc1)CN1CCCCC1
[c] Cc1cc(C)n2nc(SC(C)C(=O)Nc3ccc(Cl)cn3)nc2n1
[d] COc1ccc2c(c1)CCN(C(=O)CCl)C2C1C(=O)CCCC1=O
[e] COc1ccccc1CNC(=O)Cn1cc([N+](=O)[O-])ccc1=O
Answer: d. COc1ccc2c(c1)CCN(C(=O)CCl)C2C1C(=O)CCCC1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2c(c1)CCN(C(=O)CCl)C2C1C(=O)CCCC1=O
COc1ccc2c(c1)CCN(C(=O)CCl)C2C1C(=O)CCCC1=O
2-[2-(2-chloroacetyl)-6-methoxy-3,4-dihydro-1H-isoquinolin-1-yl]cyclohexane-1,3-dione