Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 2.980\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CCc1ccc(NC(=O)CCNC(=O)Cn2cnc3ccccc3c2=O)cc1
b.) CCOC(=O)N1CCN(C(=O)COC(=O)CNC(=O)c2ccc(Cl)cc2Cl)CC1
c.) COc1ccc(C2c3ccsc3CCN2C(=O)NC(C)(C)C)cc1
d.) COc1ccc(C2C(C#N)=C(N)Nc3onc(C(C)(C)C)c32)c(OC)c1
e.) CCOc1ccc(Nc2nc(N)c([N+](=O)[O-])c(NCc3ccccc3)n2)cc1
Answer: d. COc1ccc(C2C(C#N)=C(N)Nc3onc(C(C)(C)C)c32)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2C(C#N)=C(N)Nc3onc(C(C)(C)C)c32)c(OC)c1
COc1ccc(C2C(C#N)=C(N)Nc3onc(C(C)(C)C)c32)c(OC)c1
6-amino-3-tert-butyl-4-(2,4-dimethoxyphenyl)-4,7-dihydro-[1,2]oxazolo[5,4-b]pyridine-5-carbonitrile