Problem statement: Answer the multiple-choice question.
Query: Which compound has a -2.525\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: C[n+]1cccc(O)c1SCc1ccccc1.[Br-]
b: Cc1ccc(NC(=O)N2CCN(C/C=C/c3ccccc3)CC2)cc1
c: CC(=O)Nc1ccc2c(COC(=O)CC3Sc4ccccc4NC3=O)cc(=O)oc2c1
d: CCOC(=O)C1=C(Cn2cnc3ccccc32)NC(=O)NC1c1ccc(Cl)cc1
e: Cc1ccsc1/C=C/c1n[nH]c(=O)c(C#N)c1C
Answer: d. CCOC(=O)C1=C(Cn2cnc3ccccc32)NC(=O)NC1c1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1=C(Cn2cnc3ccccc32)NC(=O)NC1c1ccc(Cl)cc1
CCOC(=O)C1=C(Cn2cnc3ccccc32)NC(=O)NC1c1ccc(Cl)cc1
ethyl 6-(benzimidazol-1-ylmethyl)-4-(4-chlorophenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate