Problem statement: Answer the multiple-choice question.
Question: Which drug has a -21.711\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccc(OC)c(NC(=S)N2CCN(C(=O)C3CCCO3)CC2)c1
b) C=C(C)c1cccc(C(C)(C)NC(=O)Nc2ccc(C(N)=O)cc2)c1
c) Cc1cc2c(cc1S(=O)(=O)CCC(=O)Nc1cccc(C(F)(F)F)c1)OCC(=O)N2
d) O=C(CSc1nc2c(c(=O)n1-c1ccc(Br)cc1)SCC2)NCC1CCCO1
e) CCOc1ccccc1CNC(=O)CCNS(=O)(=O)c1ccc2[nH]c(=O)oc2c1
Answer: d. O=C(CSc1nc2c(c(=O)n1-c1ccc(Br)cc1)SCC2)NCC1CCCO1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CSc1nc2c(c(=O)n1-c1ccc(Br)cc1)SCC2)NCC1CCCO1
O=C(CSc1nc2c(c(=O)n1-c1ccc(Br)cc1)SCC2)NCC1CCCO1
2-[[3-(4-bromophenyl)-4-oxo-6,7-dihydrothieno[3,2-d]pyrimidin-2-yl]sulfanyl]-N-(oxolan-2-ylmethyl)acetamide