Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -47.289\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCCCn1c(CN2CCN(C(=O)OCC)CC2)nc2c1c(=O)[nH]c(=O)n2C
(b) CCCOc1ccc(C(=O)NCC2OCCc3ccccc32)cc1OC
(c) COC(=O)Oc1ccc(/C=N/NS(=O)(=O)c2ccccc2)cc1OC
(d) O=C(Nc1ccc(-n2cnnn2)cc1)C1CCCN1C(=O)Nc1ccc(Br)cc1
(e) O=C(c1cccc(Cl)c1)C1CCCN(S(=O)(=O)c2ccccc2)C1
Answer: d. O=C(Nc1ccc(-n2cnnn2)cc1)C1CCCN1C(=O)Nc1ccc(Br)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1ccc(-n2cnnn2)cc1)C1CCCN1C(=O)Nc1ccc(Br)cc1
O=C(Nc1ccc(-n2cnnn2)cc1)C1CCCN1C(=O)Nc1ccc(Br)cc1
1-N-(4-bromophenyl)-2-N-[4-(tetrazol-1-yl)phenyl]pyrrolidine-1,2-dicarboxamide