Task: Answer the MCQ question.
Query: Which drug has a -71.733\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CC(C)(OC(=O)NC(=O)C(F)(F)F)C(C)(C)OC(=O)NC(=O)C(F)(F)F
b. Oc1ccc(C2Nc3cccc4cccc(c34)N2)cc1
c. COc1ccc(Nc2nc(N)nc(CN3CCC(Cc4ccccc4)CC3)n2)cc1
d. O=C(COc1ccccc1)OCC(=O)c1ccc(O)cc1O
e. Cc1cc(C)c([C@@H]2C[C@H]3CN(C4CCCC4)C(=O)[C@]34CCCN24)c(-n2cccn2)c1
Answer: e. Cc1cc(C)c([C@@H]2C[C@H]3CN(C4CCCC4)C(=O)[C@]34CCCN24)c(-n2cccn2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cc(C)c([C@@H]2C[C@H]3CN(C4CCCC4)C(=O)[C@]34CCCN24)c(-n2cccn2)c1
Cc1cc(C)c([C@@H]2C[C@H]3CN(C4CCCC4)C(=O)[C@]34CCCN24)c(-n2cccn2)c1
(1S,5S,7S)-3-cyclopentyl-7-(2,4-dimethyl-6-pyrazol-1-ylphenyl)-3,8-diazatricyclo[6.3.0.01,5]undecan-2-one