Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -7.280\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1ccc(-c2[nH]n(-c3ccc([N+](=O)[O-])cc3)c(=O)c2C=NCc2ccccc2)cc1
b: CCOC(=O)c1ccc(NS(=O)(=O)c2c(N)[nH]c(=O)[nH]c2=O)cc1
c: COc1ccccc1N1CCN(C(=O)COc2cc(C)ccc2C)CC1
d: COc1ccc(/C=N/n2c(C)nc3ccccc3c2=O)cc1OC
e: COC(=O)c1cc(-c2ccc(Br)cc2)c2c(=O)[nH]c(=O)n(C)c2n1
Answer: c. COc1ccccc1N1CCN(C(=O)COc2cc(C)ccc2C)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1N1CCN(C(=O)COc2cc(C)ccc2C)CC1
COc1ccccc1N1CCN(C(=O)COc2cc(C)ccc2C)CC1
2-(2,5-dimethylphenoxy)-1-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone