Problem statement: Answer the MCQ question.
Query: Which drug has a 5.636\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1cc(C(=O)CSc2nnc(-c3cccnc3)n2-c2ccccc2)c(C)n1CC1CCCO1
b) CC1=C(C(=O)Nc2ccccc2)C(c2ccc(C)o2)N2C(=O)CSC2=N1
c) Cc1cnc(=O)[nH]c1SCc1ccc(C(F)(F)F)cc1
d) COC(=O)c1ccc(N2NC(=O)/C(=C/c3cc(OC)c(O)c(OC)c3)C2=O)cc1
e) CS(=O)(=O)c1ccc(Cl)c(NC(=O)c2cccc(-n3cnnn3)c2)c1
Answer: d. COC(=O)c1ccc(N2NC(=O)/C(=C/c3cc(OC)c(O)c(OC)c3)C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(N2NC(=O)/C(=C/c3cc(OC)c(O)c(OC)c3)C2=O)cc1
COC(=O)c1ccc(N2NC(=O)/C(=C/c3cc(OC)c(O)c(OC)c3)C2=O)cc1
methyl 4-[(4Z)-4-[(4-hydroxy-3,5-dimethoxyphenyl)methylidene]-3,5-dioxopyrazolidin-1-yl]benzoate