Problem statement: Answer the MCQ question.
Question: Which compound exhibits a -12.549\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] Cn1c(NC(=O)C2CC2)cc(=O)n(C)c1=O
[b] CCOC(=O)N1CCN(C(=O)CCS(=O)(=O)c2ccc(Br)s2)CC1
[c] O=c1c(Cc2ccc(F)cc2)c(O)ccn1Cc1ccco1
[d] CCN(CC)CCCN=Cc1c(O)n(-c2ccccc2C)c(=O)c2ccccc12
[e] CC1=C(C(=O)Nc2ccccc2)C(c2ccco2)C(C#N)=C(SCC(=O)OC(C)C)N1
Answer: d. CCN(CC)CCCN=Cc1c(O)n(-c2ccccc2C)c(=O)c2ccccc12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN(CC)CCCN=Cc1c(O)n(-c2ccccc2C)c(=O)c2ccccc12
CCN(CC)CCCN=Cc1c(O)n(-c2ccccc2C)c(=O)c2ccccc12
4-[3-(diethylamino)propyliminomethyl]-3-hydroxy-2-(2-methylphenyl)isoquinolin-1-one