Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -4.215\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COC(=O)c1c(C(=O)OC)c2ccccn2c1C(=O)c1ccc([N+](=O)[O-])cc1
(b) CCO[C@@H]1OC(C(=O)NCc2ccccc2)=C[C@H](c2coc3ccccc3c2=O)[C@H]1CCCO
(c) CC(C)(C)c1ccc(C(=O)NC(=S)NCC2CCCO2)cc1
(d) Cc1ccc(C(=O)NCCc2nnc3ccc(SCC(=O)Nc4ccccc4F)nn23)cc1
(e) OCCC1CN(Cc2nc3ccc(F)cc3[nH]2)CCN1C1CCCC1
Answer: b. CCO[C@@H]1OC(C(=O)NCc2ccccc2)=C[C@H](c2coc3ccccc3c2=O)[C@H]1CCCO
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCO[C@@H]1OC(C(=O)NCc2ccccc2)=C[C@H](c2coc3ccccc3c2=O)[C@H]1CCCO
CCO[C@@H]1OC(C(=O)NCc2ccccc2)=C[C@H](c2coc3ccccc3c2=O)[C@H]1CCCO
(2R,3R,4S)-N-benzyl-2-ethoxy-3-(3-hydroxypropyl)-4-(4-oxochromen-3-yl)-3,4-dihydro-2H-pyran-6-carboxamide