Problem statement: Answer the multiple choice question.
Query: What is the human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM of a compound with the SMILES COc1ccc(-c2csc3ncnc(N4CCN(C(=O)c5ccco5)CC4)c23)cc1?
Constraint: You must return none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) 12.202
(b) 4.532
(c) 1.365
(d) -6.886
(e) -12.109
Answer: e. -12.109\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
COc1ccc(-c2csc3ncnc(N4CCN(C(=O)c5ccco5)CC4)c23)cc1
COc1ccc(-c2csc3ncnc(N4CCN(C(=O)c5ccco5)CC4)c23)cc1
furan-2-yl-[4-[5-(4-methoxyphenyl)thieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl]methanone