Task: Answer the MCQ question.
Question: Which drug has a -10.477\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1cc(CCN2C(=O)c3cccc4cccc(c34)C2=O)c(S(=O)(=O)N2CCCCCC2)cc1OC
b: Cc1ccc(C)c(C(=O)COC(=O)CN2C(=O)C3C4C=CC(C4)C3C2=O)c1
c: Cc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CSc1ncc(C(F)(F)F)cc1Cl
d: CCOc1ccc(NC(=O)CN(c2cccc(C(F)(F)F)c2)S(C)(=O)=O)cc1
e: C[C@@]12C(=O)N(c3cccc(F)c3)C(=O)N1[C@H](c1ccc(Cl)cc1)[C@@H]1C(=O)N(C3CCCCC3)C(=O)[C@@H]12
Answer: c. Cc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CSc1ncc(C(F)(F)F)cc1Cl
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CSc1ncc(C(F)(F)F)cc1Cl
Cc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CSc1ncc(C(F)(F)F)cc1Cl
2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl-N-[5-(dimethylsulfamoyl)-2-methylphenyl]acetamide