Problem statement: Answer the multiple choice question.
Question: Which compound exhibits a -16.448\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C1/C(=C2/NCCN2C2CC(=O)N(c3ccccc3)C2=O)CC/C1=C\c1ccccc1
b) CC1CCC(C(=O)NC(C(=O)N2CCC3(CC2)OCCO3)C(C)C)CC1
c) O=C(CN1C(=O)S/C(=C\c2cccc(Cl)c2)C1=O)NCCCn1ccnc1
d) COc1cccc(CNC(=O)CCC2CCCN(Cc3ccc4c(c3)CCO4)C2)c1
e) COc1ccc(-c2cn[nH]c2-c2ccc(OCc3ccccc3F)cc2O)cc1OC
Answer: d. COc1cccc(CNC(=O)CCC2CCCN(Cc3ccc4c(c3)CCO4)C2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CNC(=O)CCC2CCCN(Cc3ccc4c(c3)CCO4)C2)c1
COc1cccc(CNC(=O)CCC2CCCN(Cc3ccc4c(c3)CCO4)C2)c1
3-[1-(2,3-dihydro-1-benzofuran-5-ylmethyl)piperidin-3-yl]-N-[(3-methoxyphenyl)methyl]propanamide