Problem statement: Answer the MCQ question.
Query: Which drug has a 5.877\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1cccc(-c2nc(CS(=O)(=O)CC(=O)N3CCc4ccccc4C3)c(C)o2)c1
b) CC(C)(C)c1cc(C(=O)O)nn1-c1ccccc1
c) COc1ccc(CCNC(=O)CCCN2C(=O)c3ccccc3C2=O)cc1
d) CCOc1cc(/C=C(\C#N)c2nc3ccccc3[nH]2)ccc1OC(C)C(=O)O
e) COc1ccc(N2CCN(C(=O)/C=C/c3ccco3)CC2)cc1
Answer: a. COc1cccc(-c2nc(CS(=O)(=O)CC(=O)N3CCc4ccccc4C3)c(C)o2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(-c2nc(CS(=O)(=O)CC(=O)N3CCc4ccccc4C3)c(C)o2)c1
COc1cccc(-c2nc(CS(=O)(=O)CC(=O)N3CCc4ccccc4C3)c(C)o2)c1
1-(3,4-dihydro-1H-isoquinolin-2-yl)-2-[[2-(3-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfonyl]ethanone