Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -16.277\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. O=S(=O)(c1ccccc1)c1nc(Cc2ccccc2)oc1N1CCOCC1
b. Cc1ccc(S(=O)(=O)NC(c2ccccc2)C(C)C(=O)n2nc(C)cc2C)cc1
c. CCOc1ccccc1CN1CCN(CC2=Cc3cc(OC)ccc3OC2)CC1CCO
d. COC(=O)c1ccc(CSc2nnc(Nc3ccc(OC)cc3)s2)o1
Answer: d. COC(=O)c1ccc(CSc2nnc(Nc3ccc(OC)cc3)s2)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(CSc2nnc(Nc3ccc(OC)cc3)s2)o1
COC(=O)c1ccc(CSc2nnc(Nc3ccc(OC)cc3)s2)o1
methyl 5-[[5-(4-methoxyanilino)-1,3,4-thiadiazol-2-yl]sulfanylmethyl]furan-2-carboxylate