Task: Answer the multiple choice question.
Question: Which drug exhibits a -2.978\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Cc1ccc(/C=C2/NC(=O)N(Cc3ccccc3F)C2=O)o1
b COc1ccc(C(C(N)=O)c2ncc(C(F)(F)F)cc2Cl)cc1OC
c CC1(C(=O)N(CC(=O)NC2CCCC2)C2CCCC2)CC(=O)N=C2C=CC=CN21
d COc1cnc(-c2ccccn2)nc1Oc1ccccc1Cl
e CCOC(=O)c1c(-c2ccc(C)o2)csc1NC(=O)CN1CCC(C(N)=O)CC1
Answer: e. CCOC(=O)c1c(-c2ccc(C)o2)csc1NC(=O)CN1CCC(C(N)=O)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)c1c(-c2ccc(C)o2)csc1NC(=O)CN1CCC(C(N)=O)CC1
CCOC(=O)c1c(-c2ccc(C)o2)csc1NC(=O)CN1CCC(C(N)=O)CC1
ethyl 2-[[2-(4-carbamoylpiperidin-1-yl)acetyl]amino]-4-(5-methylfuran-2-yl)thiophene-3-carboxylate