Task: Answer the MCQ question.
Query: Which drug has a 18.245\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COC(=O)C1=C(c2ccc3ccccc3c2)C[C@@H]2CC[C@H]1N2C(=O)NC1CC1
b) O=C(Nc1ccccc1)c1ccc(NCc2cccnc2)c(S(=O)(=O)N2CCOCC2)c1
c) Cc1ccc(N(CC(=O)Nc2ccc3c(c2)OCCO3)S(C)(=O)=O)cc1
d) Cc1ccc(-n2nc3c(=O)n(CC(=O)NCCc4ccc(Cl)cc4)nc(C)c3c2C)cc1
e) CCN(CC)C(=O)c1cccc(NC(=O)C2=COCCO2)c1
Answer: d. Cc1ccc(-n2nc3c(=O)n(CC(=O)NCCc4ccc(Cl)cc4)nc(C)c3c2C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(-n2nc3c(=O)n(CC(=O)NCCc4ccc(Cl)cc4)nc(C)c3c2C)cc1
Cc1ccc(-n2nc3c(=O)n(CC(=O)NCCc4ccc(Cl)cc4)nc(C)c3c2C)cc1
N-[2-(4-chlorophenyl)ethyl]-2-[3,4-dimethyl-2-(4-methylphenyl)-7-oxopyrazolo[3,4-d]pyridazin-6-yl]acetamide