Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -3.449\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1ccc2cc(OCC(=O)NNC(=O)Nc3ccc(C(C)=O)cc3)ccc2c1
[b] O=C(CCn1nc(-c2ccc(Cl)cc2)ccc1=O)NCc1cccnc1
[c] Cc1nc2cc(C(=O)NCCN3CCOCC3)ccc2n1-c1ccc(F)cc1F
[d] O=C(CCCN1C(=O)c2cccc3cccc(c23)C1=O)N1CCN(c2ccccn2)CC1
[e] Cc1ccc(NC(=O)N2CCC(NC(=O)c3ccco3)CC2)cc1
Answer: d. O=C(CCCN1C(=O)c2cccc3cccc(c23)C1=O)N1CCN(c2ccccn2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCCN1C(=O)c2cccc3cccc(c23)C1=O)N1CCN(c2ccccn2)CC1
O=C(CCCN1C(=O)c2cccc3cccc(c23)C1=O)N1CCN(c2ccccn2)CC1
2-[4-oxo-4-(1-pyridin-2-ylpiperazin-4-yl)butyl]benzo[de]isoquinoline-1,3-dione