Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 12.285\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] Cc1c(NC(=O)C23CC4CC(CC(Br)(C4)C2)C3)c(=O)n(-c2ccccc2)n1C
[b] Br.CCCCn1c(=N)n(CC(=O)C(C)(C)C)c2ccccc21
[c] O=C(Cc1ccccc1)NCC(=O)OCC(=O)c1cccs1
[d] COc1ccc(-c2csc(NCCc3nc4cc(C(=O)NCCCO)ccc4n3Cc3ccc(C)cc3)n2)cc1
[e] Cc1cccc(C(=O)NC(=S)Nc2ccccc2C(=O)O)c1
Answer: d. COc1ccc(-c2csc(NCCc3nc4cc(C(=O)NCCCO)ccc4n3Cc3ccc(C)cc3)n2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2csc(NCCc3nc4cc(C(=O)NCCCO)ccc4n3Cc3ccc(C)cc3)n2)cc1
COc1ccc(-c2csc(NCCc3nc4cc(C(=O)NCCCO)ccc4n3Cc3ccc(C)cc3)n2)cc1
N-(3-hydroxypropyl)-2-[2-[[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]amino]ethyl]-1-[(4-methylphenyl)methyl]benzimidazole-5-carboxamide