Task: Answer the multiple-choice question.
Question: Which drug has a -2.990\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1ccc(NC(=O)C2CCN(S(=O)(=O)c3cn(C)nc3C)CC2)cc1
b.) COc1cc(NC(=O)c2cccnc2Sc2ccc(C)c(C)c2)cc(OC)c1OC
c.) COc1ccc(CNC(=O)CN(Cc2ccccc2F)C(=O)c2csnn2)cc1
d.) Cc1nc(C)c(-c2nnc(-c3ccc(C(C)(C)C)cc3)o2)cc1C(=O)NN
e.) COc1ccccc1Nc1nc2ccc(C)cc2cc1C#N
Answer: c. COc1ccc(CNC(=O)CN(Cc2ccccc2F)C(=O)c2csnn2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)CN(Cc2ccccc2F)C(=O)c2csnn2)cc1
COc1ccc(CNC(=O)CN(Cc2ccccc2F)C(=O)c2csnn2)cc1
N-[(2-fluorophenyl)methyl]-N-[2-[(4-methoxyphenyl)methylamino]-2-oxoethyl]thiadiazole-4-carboxamide