Problem statement: Answer the multiple choice question.
Query: Which drug has a 12.550\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccccc1N1CCN(C2CCCN(C(=O)CCN3CCCCO3)C2)CC1
[b] O=c1oc2c3c(nn2c2ccccc12)CCCC3
[c] COC(=O)C1CN(C(=O)COc2ccc(Cl)cc2Cl)c2ccccc2O1
[d] CC(C)(C)OC(=O)NCCCCCc1cn([C@@H](CO)C(=O)NCCCCCCCCCCC(=O)N2CCN(C(=O)OC(C)(C)C)CC2)nn1
[e] CC(C)C12CN3CC(C(C)C)(CN(C1)C3c1ccccc1)C2O
Answer: a. COc1ccccc1N1CCN(C2CCCN(C(=O)CCN3CCCCO3)C2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1N1CCN(C2CCCN(C(=O)CCN3CCCCO3)C2)CC1
COc1ccccc1N1CCN(C2CCCN(C(=O)CCN3CCCCO3)C2)CC1
1-[3-[4-(2-methoxyphenyl)piperazin-1-yl]piperidin-1-yl]-3-(oxazinan-2-yl)propan-1-one