Problem statement: Answer the multiple choice question.
Question: Which drug has a 10.181\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COC(=O)C1=C(c2ccc(OC(F)(F)F)cc2)C[C@@H]2CC[C@H]1N2C(=O)NC1Cc2ccccc2C1
b) COc1ccc(CN2C(=O)c3cccnc3C2=O)cc1S(=O)(=O)NCc1ccco1
c) O=C(CNC(=O)c1nc[nH]c1C(=O)N1CCc2ccccc2C1)OCc1ccccc1
d) O=C1C(=O)N(CCCN2CCOCC2)C(c2ccc(Cl)cc2)/C1=C(\O)c1ccc2c(c1)OCCO2
e) CC1CC(C)CN(C(=O)CCCNC(=O)c2ccc(Cl)cc2)C1
Answer: d. O=C1C(=O)N(CCCN2CCOCC2)C(c2ccc(Cl)cc2)/C1=C(\O)c1ccc2c(c1)OCCO2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1C(=O)N(CCCN2CCOCC2)C(c2ccc(Cl)cc2)/C1=C(\O)c1ccc2c(c1)OCCO2
O=C1C(=O)N(CCCN2CCOCC2)C(c2ccc(Cl)cc2)/C1=C(\O)c1ccc2c(c1)OCCO2
(4E)-5-(4-chlorophenyl)-4-[2,3-dihydro-1,4-benzodioxin-6-yl(hydroxy)methylidene]-1-(3-morpholin-4-ylpropyl)pyrrolidine-2,3-dione