Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 6.379\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Cc1nn(Cc2ccc(C(=O)Nc3nc4c(C)cccc4s3)o2)c(C)c1Br
b O=C(CN1C(=O)NC(c2ccccc2)(c2ccccc2)C1=O)NCC(=O)Nc1ccc(F)cc1
c CCn1cnc2sc(C(=O)Nc3ccccc3OC)c(C)c2c1=O
d CSc1nc(S(=O)(=O)c2ccccc2)c(Cl)s1
e Cc1ccc(C(=O)Nc2nnn(C)n2)cc1
Answer: c. CCn1cnc2sc(C(=O)Nc3ccccc3OC)c(C)c2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCn1cnc2sc(C(=O)Nc3ccccc3OC)c(C)c2c1=O
CCn1cnc2sc(C(=O)Nc3ccccc3OC)c(C)c2c1=O
3-ethyl-N-(2-methoxyphenyl)-5-methyl-4-oxothieno[2,3-d]pyrimidine-6-carboxamide