Task: Answer the multiple-choice question.
Question: Which compound has a 12.381\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1ccc(-c2nc(CS(=O)(=O)CC(=O)NCc3cccc(OC)c3OC)c(C)o2)cc1
b: O=C(O)C1CCC1C(=O)Nc1nc(-c2ccc(Cl)s2)cs1
c: O=C(Nc1nnc(C2CC2)s1)c1cc(Cl)sc1Cl
d: CCOC(=O)c1sc(NC(NC(=O)c2ccco2)(C(=O)OC)C(F)(F)F)nc1C
e: COc1ccc(NS(=O)(=O)c2ccc(O)c(C(=O)OCC(=O)N3CC(C)OC(C)C3)c2)cc1
Answer: b. O=C(O)C1CCC1C(=O)Nc1nc(-c2ccc(Cl)s2)cs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(O)C1CCC1C(=O)Nc1nc(-c2ccc(Cl)s2)cs1
O=C(O)C1CCC1C(=O)Nc1nc(-c2ccc(Cl)s2)cs1
2-[[4-(5-chlorothiophen-2-yl)-1,3-thiazol-2-yl]carbamoyl]cyclobutane-1-carboxylic acid