Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 5.805\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(N(CC(=O)NCc2ccco2)S(C)(=O)=O)cc1Cl
(b) Cc1nc2ccccn2c1C(=O)NN=C1CCN(C)CC1
(c) Cc1ccc(C)c(Cn2c3ccccc3c3cnn(CC(=O)NCCCN4CCOCC4)c(=O)c32)c1
(d) N=c1c(C(=O)NCCN2CCOCC2)cc2c(=O)n3ccccc3nc2n1Cc1ccc(F)cc1
(e) CCOC(=O)N1CCN(c2c(NCc3ccc(Cl)cc3)c(=O)c2=O)CC1
Answer: c. Cc1ccc(C)c(Cn2c3ccccc3c3cnn(CC(=O)NCCCN4CCOCC4)c(=O)c32)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(C)c(Cn2c3ccccc3c3cnn(CC(=O)NCCCN4CCOCC4)c(=O)c32)c1
Cc1ccc(C)c(Cn2c3ccccc3c3cnn(CC(=O)NCCCN4CCOCC4)c(=O)c32)c1
2-[5-[(2,5-dimethylphenyl)methyl]-4-oxopyridazino[4,5-b]indol-3-yl]-N-(3-morpholin-4-ylpropyl)acetamide