Task: Answer the MCQ question.
Question: Which drug exhibits a 3.940\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. C=CCN1C(=O)C(C)(C)Nc2ccccc21
b. COc1ccc(C)cc1NC(=O)C1CCCN1S(=O)(=O)c1ccc2c(c1)CCC(=O)N2
c. Cc1cccc2cc(C(c3nnnn3Cc3ccccc3)N3CCN(c4ccccc4)CC3)c(=O)[nH]c12
d. COc1ccccc1NC(=S)N(Cc1cn(C)nc1C)C1CC(=O)N(c2c(Cl)cccc2Cl)C1=O
Answer: d. COc1ccccc1NC(=S)N(Cc1cn(C)nc1C)C1CC(=O)N(c2c(Cl)cccc2Cl)C1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1NC(=S)N(Cc1cn(C)nc1C)C1CC(=O)N(c2c(Cl)cccc2Cl)C1=O
COc1ccccc1NC(=S)N(Cc1cn(C)nc1C)C1CC(=O)N(c2c(Cl)cccc2Cl)C1=O
1-[1-(2,6-dichlorophenyl)-2,5-dioxopyrrolidin-3-yl]-1-[(1,3-dimethylpyrazol-4-yl)methyl]-3-(2-methoxyphenyl)thiourea