Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 14.913\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=[N+]([O-])c1ccc(Cl)c(-c2ccc(/C=N/c3c(-c4ccco4)nc4ccccn34)o2)c1
b) CCn1cc(C(=O)NCc2ccccc2OC)c(=O)c2cc(S(=O)(=O)N(C)C)ccc21
c) CCCc1cc(=O)oc2cc(C)cc(OCC(=O)NC(Cc3c[nH]c4ccc(O)cc34)C(=O)O)c12
d) COC(=O)C1=C(COc2ccc(C=O)cc2OC)NC(=O)NC1c1cc(C)ccc1C
e) Cc1cccc(NC(=O)c2cccc(OC(=S)N3CCOCC3)c2)c1C
Answer: d. COC(=O)C1=C(COc2ccc(C=O)cc2OC)NC(=O)NC1c1cc(C)ccc1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(COc2ccc(C=O)cc2OC)NC(=O)NC1c1cc(C)ccc1C
COC(=O)C1=C(COc2ccc(C=O)cc2OC)NC(=O)NC1c1cc(C)ccc1C
methyl 4-(2,5-dimethylphenyl)-6-[(4-formyl-2-methoxyphenoxy)methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate