Task: Answer the multiple choice question.
Question: Which drug has a -2.723\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CC(=O)Nc1nc2cc(N)ccc2s1
b: O=C(Cc1cccc(C(F)(F)F)c1)OCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
c: Fc1c(F)c(C(F)(F)F)c(F)c(F)c1N/N=C\c1cccs1
d: Oc1cc2c(cc1CN1CCN(c3ccc(F)cc3)CC1)OCO2
e: COC(=O)C1=C(C)N(C2CCCCC2)C(=O)/C1=C\c1cccs1
Answer: b. O=C(Cc1cccc(C(F)(F)F)c1)OCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Cc1cccc(C(F)(F)F)c1)OCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
O=C(Cc1cccc(C(F)(F)F)c1)OCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
[2-[4-(4-chlorophenyl)sulfonylpiperazin-1-yl]-2-oxoethyl] 2-[3-(trifluoromethyl)phenyl]acetate