Problem statement: Answer the MCQ question.
Query: Which compound has a -14.782\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1cccc(CNc2cccc(C(F)(F)F)c2)c1O
b O=C(Nc1cccc(OC(=O)c2ccco2)c1)c1ccco1
c CCOC(=O)C1(Cc2ccccc2C(F)(F)F)CCN(C(C)CSC)CC1
d COC(=O)c1ccccc1S(=O)(=O)N(CCCO)Cc1cc2c(C)ccc(C)c2[nH]c1=O
e CCN1C(=O)/C(=C\N(C)C)S/C1=N\S(=O)(=O)c1ccccc1
Answer: d. COC(=O)c1ccccc1S(=O)(=O)N(CCCO)Cc1cc2c(C)ccc(C)c2[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccccc1S(=O)(=O)N(CCCO)Cc1cc2c(C)ccc(C)c2[nH]c1=O
COC(=O)c1ccccc1S(=O)(=O)N(CCCO)Cc1cc2c(C)ccc(C)c2[nH]c1=O
methyl 2-[(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl-(3-hydroxypropyl)sulfamoyl]benzoate