Problem statement: Answer the multiple-choice question.
Question: Which drug has a -12.685\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Cc1sc2nc(C)n(/N=C/c3ccc(O)cc3)c(=O)c2c1C
b CCN1CCN(CCNC(=O)c2ccc(CS(=O)c3ccc(Br)cc3)o2)CC1
c CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(=O)n(Cc3ccc(Cl)c(Cl)c3)c2)cc1
d CCOC(=O)CNC(=O)CNC(=O)c1ccc(OC(C)C)cc1
e O=C(c1ccc2c(c1)OCO2)N1CCN(c2ccc(F)cc2)CC1
Answer: c. CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(=O)n(Cc3ccc(Cl)c(Cl)c3)c2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(=O)n(Cc3ccc(Cl)c(Cl)c3)c2)cc1
CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(=O)n(Cc3ccc(Cl)c(Cl)c3)c2)cc1
N-[4-[[1-[(3,4-dichlorophenyl)methyl]-6-oxopyridin-3-yl]sulfamoyl]phenyl]acetamide