Problem statement: Answer the MCQ question.
Question: Which drug has a -2.529\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: Cc1ccc(S(=O)(=O)N2CCN(C(=O)N3CCOCC3)CC2)cc1C
b: OC1(c2cccs2)CN(c2ccc(Cl)cc2)C2=[N+]1CCCS2.[Br-]
c: [Br-].c1ccc(C[n+]2csc3ccccc32)cc1
d: Cc1cccc(CNC(=O)C(C)n2nc(C)c3c(C)n(-c4ccccc4)nc3c2=O)c1
e: Cc1ccsc1C1C(C#N)=C(N)OC2=C1C(=O)CCC2
Answer: d. Cc1cccc(CNC(=O)C(C)n2nc(C)c3c(C)n(-c4ccccc4)nc3c2=O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cccc(CNC(=O)C(C)n2nc(C)c3c(C)n(-c4ccccc4)nc3c2=O)c1
Cc1cccc(CNC(=O)C(C)n2nc(C)c3c(C)n(-c4ccccc4)nc3c2=O)c1
2-(3,4-dimethyl-7-oxo-2-phenylpyrazolo[3,4-d]pyridazin-6-yl)-N-[(3-methylphenyl)methyl]propanamide