Problem statement: Answer the MCQ question.
Question: Which drug has a 11.542\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] CCCC(=O)Nc1nnc(CCN2CCCCC2)s1
[b] COc1ccc(Cl)cc1NC(=O)C(C)OC(=O)Cn1cc(C(F)(F)F)ccc1=O
[c] CCOCCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccccc1Cl
[d] CC(C)(C)N(C(=O)Cn1nnc(-c2ccc(F)cc2)n1)C(C(=O)NC1CCCC1)c1ccncc1.Cl
Answer: b. COc1ccc(Cl)cc1NC(=O)C(C)OC(=O)Cn1cc(C(F)(F)F)ccc1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(Cl)cc1NC(=O)C(C)OC(=O)Cn1cc(C(F)(F)F)ccc1=O
COc1ccc(Cl)cc1NC(=O)C(C)OC(=O)Cn1cc(C(F)(F)F)ccc1=O
[1-(5-chloro-2-methoxyanilino)-1-oxopropan-2-yl] 2-[2-oxo-5-(trifluoromethyl)pyridin-1-yl]acetate