Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -3.806\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) O=C(NC(=O)c1cccc(OC(F)(F)C(F)F)c1)OC1CCS(=O)(=O)C1
b.) O=C1c2[nH]nc(-c3ccccc3O)c2C(c2ccc(F)cc2)N1Cc1ccco1
c.) COc1ccc(N2CCN(S(=O)(=O)c3ccc(Br)s3)CC2)cc1
d.) Cl.N[C@@H]1C[C@H]1c1ccccc1
e.) COc1cccc(CNC(=O)C2CCN(S(=O)(=O)c3ccc4c(c3)CC(C)N4C(=O)C3CC3)CC2)c1
Answer: a. O=C(NC(=O)c1cccc(OC(F)(F)C(F)F)c1)OC1CCS(=O)(=O)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NC(=O)c1cccc(OC(F)(F)C(F)F)c1)OC1CCS(=O)(=O)C1
O=C(NC(=O)c1cccc(OC(F)(F)C(F)F)c1)OC1CCS(=O)(=O)C1
(1,1-dioxothiolan-3-yl) N-[3-(1,1,2,2-tetrafluoroethoxy)benzoyl]carbamate