Task: Answer the MCQ question.
Query: Which drug exhibits a 12.684\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) Cc1ccc(S(=O)(=O)N(C)c2ccccc2C(=O)Nc2ccc(CC#N)cc2)cc1
b.) CNC(=O)C(NC(=O)CNC(=O)c1ccc(Cl)cc1)C(C)(C)C
c.) CC(O)C(O)C(O)C(O)/C=N/NC(=O)COc1ccc(Cl)cc1Cl
d.) CN1C[C@@H]2C(c3ccccc3)C3(c4ccc(C#N)cc4)CC2(C3)[C@H]1c1ccccc1
e.) N#CCP(=S)(c1ccccc1)c1ccccc1
Answer: d. CN1C[C@@H]2C(c3ccccc3)C3(c4ccc(C#N)cc4)CC2(C3)[C@H]1c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1C[C@@H]2C(c3ccccc3)C3(c4ccc(C#N)cc4)CC2(C3)[C@H]1c1ccccc1
CN1C[C@@H]2C(c3ccccc3)C3(c4ccc(C#N)cc4)CC2(C3)[C@H]1c1ccccc1
4-[(2S,5R)-3-methyl-2,6-diphenyl-3-azatricyclo[5.1.1.01,5]nonan-7-yl]benzonitrile