Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -15.534\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccccc1C(=O)Nc1c(-c2ccccc2)nc2ccccn12
b) COC(=O)c1ccc(N2CN=C(c3ccc(C)cc3)NC2=S)cc1
c) COc1cc(OC)c(OC)cc1CN1CCCC(C(=O)c2ccccc2SC)C1
d) O=C(Nc1ccccc1C(=O)O)c1cc(S(=O)(=O)N2CCCCC2)cs1
e) Clc1cccc(/C=N/Nc2nc(Cl)nc3ccccc23)c1
Answer: c. COc1cc(OC)c(OC)cc1CN1CCCC(C(=O)c2ccccc2SC)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(OC)c(OC)cc1CN1CCCC(C(=O)c2ccccc2SC)C1
COc1cc(OC)c(OC)cc1CN1CCCC(C(=O)c2ccccc2SC)C1
(2-methylsulfanylphenyl)-[1-[(2,4,5-trimethoxyphenyl)methyl]piperidin-3-yl]methanone