Task: Answer the multiple-choice question.
Question: Which drug has a -22.070\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCOC(=O)c1c(C)[nH]c2cc(Br)c(O)cc12
b. O=C(NCCN1CCOCC1)c1cccc(S(=O)(=O)Nc2ccc(F)cc2)c1
c. O=C(NCCCCc1ccccc1)Nc1ccc(F)cc1F
d. COc1cc(OC)cc(C(=O)Nc2cccc3cccnc23)c1
e. O=C(c1ccco1)N1CCN(c2nc3ccccc3c(=O)n2-c2ccccc2)CC1
Answer: e. O=C(c1ccco1)N1CCN(c2nc3ccccc3c(=O)n2-c2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccco1)N1CCN(c2nc3ccccc3c(=O)n2-c2ccccc2)CC1
O=C(c1ccco1)N1CCN(c2nc3ccccc3c(=O)n2-c2ccccc2)CC1
2-[4-(furan-2-carbonyl)piperazin-1-yl]-3-phenylquinazolin-4-one