Problem statement: Answer the multiple-choice question.
Question: Which compound has a -53.049\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CCCSc1nc2sc3c(c2c(=O)[nH]1)CC(C)(CC)OC3
b.) NC(=O)c1ccsc1NC(=O)COC(=O)COc1ccccc1F
c.) CC(=O)Nc1ccc(NC(=O)COC(=O)CCc2nc3ccccc3s2)cc1
d.) O=C(c1ccc2c(c1)OCO2)C1CCCN(Cc2ccc(OC(F)F)cc2)C1
e.) CCN(CC(=O)NCc1cccs1)C(=O)CCc1c[nH]c2ccccc12
Answer: d. O=C(c1ccc2c(c1)OCO2)C1CCCN(Cc2ccc(OC(F)F)cc2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccc2c(c1)OCO2)C1CCCN(Cc2ccc(OC(F)F)cc2)C1
O=C(c1ccc2c(c1)OCO2)C1CCCN(Cc2ccc(OC(F)F)cc2)C1
1,3-benzodioxol-5-yl-[1-[[4-(difluoromethoxy)phenyl]methyl]piperidin-3-yl]methanone