Problem statement: Answer the MCQ question.
Question: Which drug has a -5.110\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] O=C(COC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1)NCc1ccccc1
[b] CCOc1ccc(C(=O)NCC(=O)OCC(=O)Nc2cccc(S(=O)(=O)N3CCCC3)c2)cc1
[c] CC1(C)CCC(=O)N2CC[C@H]3C[C@H](OC(=O)Nc4ccccc4)C[C@@H]1[C@H]32
[d] COc1cccc(/C=C/c2n[nH]c(=O)c(C#N)c2C)c1
[e] CC(C)C12CN3CC(C(C)C)(CN(C1)C3(C)C)C2=O
Answer: a. O=C(COC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1)NCc1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1)NCc1ccccc1
O=C(COC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1)NCc1ccccc1
[2-(benzylamino)-2-oxoethyl] 1-thiophen-2-ylsulfonylpiperidine-4-carboxylate