Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 2.582\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. Cc1ccc(NC(=O)C2(N(C(=O)Cn3nnnc3N)c3ccc(C)cc3)CCCCC2)cc1
b. COc1cc(/C=C2/C(=N)N3C(c4ccccc4)=CSC3=NC2=O)ccc1OCC(=O)O
c. CCOC(=O)N1CCN(C(=O)CSc2ccc(-c3ccccc3OC)nn2)CC1
d. CCOc1ccc(Cn2nnc(C(=O)Nc3ccc(OC)cc3OC)c2N)cc1
e. COc1ccc(S(=O)(=O)NC2CCCCC2)cc1C(=O)N1CCCCC1
Answer: c. CCOC(=O)N1CCN(C(=O)CSc2ccc(-c3ccccc3OC)nn2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(C(=O)CSc2ccc(-c3ccccc3OC)nn2)CC1
CCOC(=O)N1CCN(C(=O)CSc2ccc(-c3ccccc3OC)nn2)CC1
ethyl 4-[2-[6-(2-methoxyphenyl)pyridazin-3-yl]sulfanylacetyl]piperazine-1-carboxylate