Problem statement: Answer the multiple-choice question.
Question: Which drug has a -2.437\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1ccc(S(=O)(=O)N2CCCC(C(=O)NCc3cccnc3)C2)cc1
b COc1cc2c(cc1OC)CN(C(=O)c1ccco1)CC2
c CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(NC(=O)C[C@@H]4NC(=O)[C@H](Cc5ccccc5)NC4=O)c3)cc2C(F)(F)F)CC1
d CC(=O)c1ccc(OC(=O)N(C)c2ccccc2)cc1
e Cc1ccc(C(=O)Nc2cc3ccccc3oc2=O)cc1
Answer: a. COc1ccc(S(=O)(=O)N2CCCC(C(=O)NCc3cccnc3)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)N2CCCC(C(=O)NCc3cccnc3)C2)cc1
COc1ccc(S(=O)(=O)N2CCCC(C(=O)NCc3cccnc3)C2)cc1
1-(4-methoxyphenyl)sulfonyl-N-(pyridin-3-ylmethyl)piperidine-3-carboxamide