Problem statement: Answer the MCQ question.
Query: Which drug has a 5.205\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) Cc1ccccc1OCCC(=O)OCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
b.) CC(NC(=O)N1CCOCC1)c1ccccc1
c.) CN1CC(C(=O)c2ccccc2)C(c2ccccc2)C1
d.) COc1ccc(CNC(=O)C2CCCN2S(=O)(=O)c2ccc(S(=O)(=O)N(C)C)cc2)cc1
Answer: d. COc1ccc(CNC(=O)C2CCCN2S(=O)(=O)c2ccc(S(=O)(=O)N(C)C)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C2CCCN2S(=O)(=O)c2ccc(S(=O)(=O)N(C)C)cc2)cc1
COc1ccc(CNC(=O)C2CCCN2S(=O)(=O)c2ccc(S(=O)(=O)N(C)C)cc2)cc1
1-[4-(dimethylsulfamoyl)phenyl]sulfonyl-N-[(4-methoxyphenyl)methyl]pyrrolidine-2-carboxamide