Problem statement: Answer the multiple-choice question.
Query: Which compound has a -0.640\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1ccc(C2CC(c3cccs3)=NN2S(C)(=O)=O)cc1OC
b CC(C)(C)c1ccccc1NC(=O)c1ccc2c(c1)SC1=NS(=O)(=O)CCN12
c CCc1nccn1CCC(=O)N1CCCC(N2CCN(c3cccc(Cl)c3)CC2)C1
d COc1cccc(NC(=O)CN(C)C(=O)COc2ccccc2Cc2ccccc2)c1
e CCOc1ccc(N2C(=O)CC(N3CCN(C(=O)c4ccco4)CC3)C2=O)cc1
Answer: e. CCOc1ccc(N2C(=O)CC(N3CCN(C(=O)c4ccco4)CC3)C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(N2C(=O)CC(N3CCN(C(=O)c4ccco4)CC3)C2=O)cc1
CCOc1ccc(N2C(=O)CC(N3CCN(C(=O)c4ccco4)CC3)C2=O)cc1
1-(4-ethoxyphenyl)-3-[4-(furan-2-carbonyl)piperazin-1-yl]pyrrolidine-2,5-dione