Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 15.182\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: Cc1ccc(S(=O)(=O)N[C@@H](CCCCN)C(=O)CCl)cc1.Cl
b: CCN(CC)CCN1C(=O)C2C(C(=O)Nc3ccc(C(C)C)cc3)C3C=CC2(O3)C1C(=O)NC1CCCCC1
c: Cc1ccc(C(=O)C2Oc3ccccc3C3CC(c4ccc(C)cc4)=NN23)cc1
d: NC(=O)c1nsc(C(=O)N(c2ccccc2)C(C(=O)NC2CCCC2)c2cccs2)c1N
e: OCCOCCn1c(C(CO)Nc2nc(-c3ccc(Cl)cc3)cs2)nc2ccccc21
Answer: b. CCN(CC)CCN1C(=O)C2C(C(=O)Nc3ccc(C(C)C)cc3)C3C=CC2(O3)C1C(=O)NC1CCCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN(CC)CCN1C(=O)C2C(C(=O)Nc3ccc(C(C)C)cc3)C3C=CC2(O3)C1C(=O)NC1CCCCC1
CCN(CC)CCN1C(=O)C2C(C(=O)Nc3ccc(C(C)C)cc3)C3C=CC2(O3)C1C(=O)NC1CCCCC1
2-N-cyclohexyl-3-[2-(diethylamino)ethyl]-4-oxo-6-N-(4-propan-2-ylphenyl)-10-oxa-3-azatricyclo[5.2.1.01,5]dec-8-ene-2,6-dicarboxamide