Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -14.416\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: O=C1c2oc3ccc(Cl)cc3c(=O)c2C(c2cccc(Br)c2)N1CCO
b: COc1ccccc1C(=O)C1CCCN(C(=O)c2snnc2C)C1
c: CCOc1ccc(C(=O)N2CCCC(c3nc(-c4ccc(C)o4)no3)C2)cc1
d: CCCCN(CC)Cc1c(C)[nH]c2c(ccc3ccccc32)c1=O
e: Cn1c(=O)[nH]c(=O)c2c1nc(NCc1ccco1)n2Cc1ccccc1Cl
Answer: c. CCOc1ccc(C(=O)N2CCCC(c3nc(-c4ccc(C)o4)no3)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(C(=O)N2CCCC(c3nc(-c4ccc(C)o4)no3)C2)cc1
CCOc1ccc(C(=O)N2CCCC(c3nc(-c4ccc(C)o4)no3)C2)cc1
(4-ethoxyphenyl)-[3-[3-(5-methylfuran-2-yl)-1,2,4-oxadiazol-5-yl]piperidin-1-yl]methanone