Task: Answer the MCQ question.
Question: Which drug exhibits a -34.496\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a. CCC(Sc1nc(-c2ccccc2)c(C#N)c(=O)[nH]1)C(=O)Nc1cc(C)on1
b. COc1cccc(CNC(=O)CCC2CCCN(C/C=C/c3ccccc3OC)C2)c1
c. Cc1noc2ncnc(Oc3ccccc3)c12
Answer: b. COc1cccc(CNC(=O)CCC2CCCN(C/C=C/c3ccccc3OC)C2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CNC(=O)CCC2CCCN(C/C=C/c3ccccc3OC)C2)c1
COc1cccc(CNC(=O)CCC2CCCN(C/C=C/c3ccccc3OC)C2)c1
N-[(3-methoxyphenyl)methyl]-3-[1-[(E)-3-(2-methoxyphenyl)prop-2-enyl]piperidin-3-yl]propanamide