Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 0.912\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccccc1C1CC(=O)NC(C)=C1C(=O)OC(C)C
b) O=C(c1ccc(Cl)c(Cl)c1)N1CCC(=O)N(C(COCc2ccc(Cl)cc2)Cc2ccccc2)CC1
c) O=C(Cc1ccccc1)Nc1ccc(NC(=O)c2ccco2)cc1
d) CN(C)CCCNc1ncnc2scc(-c3ccccc3)c12.O=C(O)C(=O)O
e) O=C(NC(Cc1ccccc1)C(=O)O)C1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1
Answer: b. O=C(c1ccc(Cl)c(Cl)c1)N1CCC(=O)N(C(COCc2ccc(Cl)cc2)Cc2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccc(Cl)c(Cl)c1)N1CCC(=O)N(C(COCc2ccc(Cl)cc2)Cc2ccccc2)CC1
O=C(c1ccc(Cl)c(Cl)c1)N1CCC(=O)N(C(COCc2ccc(Cl)cc2)Cc2ccccc2)CC1
4-[1-[(4-chlorophenyl)methoxy]-3-phenylpropan-2-yl]-1-(3,4-dichlorobenzoyl)-1,4-diazepan-5-one