Problem statement: Answer the MCQ question.
Question: Which drug has a -27.634\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1ccccc1N1CCN(/N=C/c2cc(OC)c(O)c(OC)c2)CC1
b COc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(CN2CCCCC2)cc1
c CCN(CC)CCNC(=O)C1(O)c2cc(Br)ccc2NC(=O)N1c1ccc(C)c(C)c1
d O=C(Cc1ccsc1)Nc1ccc(Cl)cc1Cl
e CC(=O)c1cccc(OCC(=O)N2CCCc3ccccc32)c1
Answer: b. COc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(CN2CCCCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(CN2CCCCC2)cc1
COc1c(Cl)cc(Cl)cc1C(=O)Nc1ccc(CN2CCCCC2)cc1
3,5-dichloro-2-methoxy-N-[4-(piperidin-1-ylmethyl)phenyl]benzamide