Problem statement: Answer the multiple-choice question.
Question: Which compound has a 13.331\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] O=C(NC1CCS(=O)(=O)C1)c1cccc(S(=O)(=O)N2CCCCCC2)c1
[b] CCCCN1C(=O)C(=O)NC[C@@H]1C(C)CC
[c] CC(C)CN1C(=O)C(=O)N(CC(=O)Nc2cc(Cl)ccc2Oc2ccccc2)C1=O
[d] COc1ccc(NC(=S)N2CCC(Cc3ccccc3)CC2)cc1OC
[e] COc1ccc(CNC(=O)C(c2ccco2)N(C(=O)c2snc(C(N)=O)c2N)c2cccc(OC)c2)cc1
Answer: e. COc1ccc(CNC(=O)C(c2ccco2)N(C(=O)c2snc(C(N)=O)c2N)c2cccc(OC)c2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C(c2ccco2)N(C(=O)c2snc(C(N)=O)c2N)c2cccc(OC)c2)cc1
COc1ccc(CNC(=O)C(c2ccco2)N(C(=O)c2snc(C(N)=O)c2N)c2cccc(OC)c2)cc1
4-amino-5-N-[1-(furan-2-yl)-2-[(4-methoxyphenyl)methylamino]-2-oxoethyl]-5-N-(3-methoxyphenyl)-1,2-thiazole-3,5-dicarboxamide