Problem statement: Answer the multiple-choice question.
Query: Which compound has a 11.220\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] Cc1ccc(S(=O)(=O)N2CCN(Cc3cccc(F)c3)CC2)cc1
[b] CC(=O)c1ccc(S(=O)(=O)Nc2cccc(-c3ccc(N4CCOCC4)nn3)c2)cc1
[c] Nc1nn(-c2ccccc2Cl)cc1-c1nn[nH]n1
[d] O=C(Cn1c(=O)oc2cccnc21)Nc1ccc(C(F)(F)F)cc1
[e] O=C(C1CCC(CNS(=O)(=O)c2cccs2)CC1)N1CCN(c2ccc(Cl)cc2)CC1
Answer: d. O=C(Cn1c(=O)oc2cccnc21)Nc1ccc(C(F)(F)F)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Cn1c(=O)oc2cccnc21)Nc1ccc(C(F)(F)F)cc1
O=C(Cn1c(=O)oc2cccnc21)Nc1ccc(C(F)(F)F)cc1
2-(2-oxo-[1,3]oxazolo[4,5-b]pyridin-3-yl)-N-[4-(trifluoromethyl)phenyl]acetamide