Task: Answer the multiple choice question.
Question: Which drug has a -18.248\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1ccc(CC(=O)Nc2ccc(C#N)c(Cl)c2)cc1S(=O)(=O)N1CCOCC1
b Cc1ccc(OCCNC(=O)CNC(=O)c2ccc3c(c2)OCO3)cc1
c COc1ccc(N=CC2=C(Nc3ccc(OC)cc3)c3c(C)nn(-c4ccccn4)c3CC2)cc1
d CC1(C)CC(=O)C2=C(C1)OC(c1cccs1)C(C#N)=C2N
e C=CCN1C(=O)C(Cc2ccc(F)cc2)S/C1=N/N=C/c1ccco1
Answer: a. COc1ccc(CC(=O)Nc2ccc(C#N)c(Cl)c2)cc1S(=O)(=O)N1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CC(=O)Nc2ccc(C#N)c(Cl)c2)cc1S(=O)(=O)N1CCOCC1
COc1ccc(CC(=O)Nc2ccc(C#N)c(Cl)c2)cc1S(=O)(=O)N1CCOCC1
N-(3-chloro-4-cyanophenyl)-2-(4-methoxy-5-morpholin-4-ylsulfonylphenyl)acetamide