Task: Answer the multiple-choice question.
Question: Which compound exhibits a -12.405\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COC(=O)CSc1nnc([C@H](CC(C)C)NC(=O)OC(C)(C)C)o1
b.) N#C/C(=C\c1ccc(OCCN2CCOCC2)cc1)C(=O)Nc1ccccc1F
c.) O=C(CCn1ccnc1)Nc1cc(Cl)ccc1O
d.) Cc1ccc2nc(Cn3cc(C(F)(F)F)ccc3=O)cc(=O)n2c1
e.) CC(=O)n1cc([C@H]2C=C(C(N)=O)O[C@@H](OCc3ccc(CO)cc3)C2)c2ccccc21
Answer: a. COC(=O)CSc1nnc([C@H](CC(C)C)NC(=O)OC(C)(C)C)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)CSc1nnc([C@H](CC(C)C)NC(=O)OC(C)(C)C)o1
COC(=O)CSc1nnc([C@H](CC(C)C)NC(=O)OC(C)(C)C)o1
methyl 2-[[5-[(1S)-3-methyl-1-[(2-methylpropan-2-yl)oxycarbonylamino]butyl]-1,3,4-oxadiazol-2-yl]sulfanyl]acetate