Problem statement: Answer the MCQ question.
Question: Which drug has a 17.121\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CCOc1ccc(C(=O)N2CCN(S(=O)(=O)c3cccs3)CC2)c(OCC)c1
b O=C(Oc1cccnc1)c1cc(S(=O)(=O)N2CCCCC2)ccc1Cl
c COc1ccc(C)cc1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)c(=O)n(C)c(=O)n2C
d COc1ccccc1N1CCN(c2ncnc3sc(C(=O)NCC4CCCO4)c(C)c23)CC1
e COCCOC(=O)c1c(C)n(C)c2ccc(OC(=O)c3cccs3)cc12
Answer: d. COc1ccccc1N1CCN(c2ncnc3sc(C(=O)NCC4CCCO4)c(C)c23)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1N1CCN(c2ncnc3sc(C(=O)NCC4CCCO4)c(C)c23)CC1
COc1ccccc1N1CCN(c2ncnc3sc(C(=O)NCC4CCCO4)c(C)c23)CC1
4-[4-(2-methoxyphenyl)piperazin-1-yl]-5-methyl-N-(oxolan-2-ylmethyl)thieno[2,3-d]pyrimidine-6-carboxamide