Problem statement: Answer the multiple choice question.
Query: Which drug has a -41.782\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a O=C1CN(C(=O)COC(=O)C2CCN(S(=O)(=O)c3ccccc3C(F)(F)F)CC2)c2ccccc2N1
b O=C(c1cc(Br)c(Br)s1)N1CCN(c2ccccn2)CC1
c COc1cc(CN2CCN(CCc3ccccc3)C(CCO)C2)cc(OC)c1
d O=c1[nH]c2cc3c(cc2cc1CN(Cc1ccco1)C(=S)NCC1CCCO1)OCCO3
Answer: c. COc1cc(CN2CCN(CCc3ccccc3)C(CCO)C2)cc(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(CN2CCN(CCc3ccccc3)C(CCO)C2)cc(OC)c1
COc1cc(CN2CCN(CCc3ccccc3)C(CCO)C2)cc(OC)c1
2-[4-[(3,5-dimethoxyphenyl)methyl]-1-(2-phenylethyl)piperazin-2-yl]ethanol