Task: Answer the multiple choice question.
Question: Which drug has a -17.727\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a. CCN1CCN(c2ncc(C(=O)Nc3c(F)cc(F)cc3Br)c3ccccc23)CC1
b. CC(=O)Nc1cc(NC(C)=O)cc(C(=O)OC(C)C(=O)Nc2ccc(S(=O)(=O)N3CCCC3)cc2)c1
c. Cc1ccc(NC(=O)c2ccccc2F)c(NC(=O)c2ccccc2F)c1
Answer: a. CCN1CCN(c2ncc(C(=O)Nc3c(F)cc(F)cc3Br)c3ccccc23)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN1CCN(c2ncc(C(=O)Nc3c(F)cc(F)cc3Br)c3ccccc23)CC1
CCN1CCN(c2ncc(C(=O)Nc3c(F)cc(F)cc3Br)c3ccccc23)CC1
N-(2-bromo-4,6-difluorophenyl)-1-(4-ethyl-1,4-diazinan-1-yl)isoquinoline-4-carboxamide