Task: Answer the multiple-choice question.
Query: Which drug has a 11.634\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C(c1cccc([N+](=O)[O-])c1)N1CCN(Cc2ccc3c(c2)OCO3)CC1
b. N#CCc1c(C#N)c(N)nc(N2CCN(C=O)CC2)c1C#N
c. COc1ccc(OCC(=O)N/N=C(\C)CC(=O)Nc2ccc(NC(C)=O)cc2)cc1
d. CCS(=O)(=O)NCC(c1cccnc1)N1CCN(c2ccccc2)CC1
e. O=C(COC(=O)[C@@H]1CCCN1C(=O)c1cccs1)NCCc1ccccc1
Answer: e. O=C(COC(=O)[C@@H]1CCCN1C(=O)c1cccs1)NCCc1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COC(=O)[C@@H]1CCCN1C(=O)c1cccs1)NCCc1ccccc1
O=C(COC(=O)[C@@H]1CCCN1C(=O)c1cccs1)NCCc1ccccc1
[2-oxo-2-(2-phenylethylamino)ethyl] (2S)-1-(thiophene-2-carbonyl)pyrrolidine-2-carboxylate