Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 11.588\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. COc1ccc(C(=O)C2CCCN(Cc3cnc(N4CCOCC4)s3)C2)c(OC)c1
b. COC(=O)Nc1nnc(SCc2ccc(C)cc2)s1
c. C=CCn1c(SCc2nc3cc(C(F)(F)F)ccc3c(=O)[nH]2)nc2sc(CC)cc2c1=O
d. Cc1nnc(SCCn2c(N3CC(C)CC(C)C3)nc3c2c(=O)[nH]c(=O)n3C)s1
Answer: c. C=CCn1c(SCc2nc3cc(C(F)(F)F)ccc3c(=O)[nH]2)nc2sc(CC)cc2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C=CCn1c(SCc2nc3cc(C(F)(F)F)ccc3c(=O)[nH]2)nc2sc(CC)cc2c1=O
C=CCn1c(SCc2nc3cc(C(F)(F)F)ccc3c(=O)[nH]2)nc2sc(CC)cc2c1=O
6-ethyl-2-[[4-oxo-7-(trifluoromethyl)-3H-quinazolin-2-yl]methylsulfanyl]-3-prop-2-enylthieno[2,3-d]pyrimidin-4-one