Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -1.327\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(C(=O)O/N=C/c2ccc(S(=O)(=O)c3ccc(Cl)cc3)nc2)cc1
(b) CCc1cccc(CC)c1NC(=O)CSc1nc2ccc(N3C(=O)C4C5C=CC(C5)C4C3=O)cc2s1
(c) CS(=O)(=O)N(CC(=O)Nc1ccc(S(=O)(=O)N2CCOCC2)cc1)c1ccccc1Cl
(d) C=Cc1ccc2c(c1)N(C)C(=C)S2.I
(e) N#Cc1ccccc1CSCCNC(=O)Cc1c(F)cccc1Cl
Answer: a. COc1ccc(C(=O)O/N=C/c2ccc(S(=O)(=O)c3ccc(Cl)cc3)nc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)O/N=C/c2ccc(S(=O)(=O)c3ccc(Cl)cc3)nc2)cc1
COc1ccc(C(=O)O/N=C/c2ccc(S(=O)(=O)c3ccc(Cl)cc3)nc2)cc1
[(E)-[6-(4-chlorophenyl)sulfonylpyridin-3-yl]methylideneamino] 4-methoxybenzoate