Task: Answer the multiple choice question.
Question: Which drug has a 10.087\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. COc1ccccc1NC(=S)NCCSc1ccc(Cl)cc1
b. COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCOCC1
c. CC(C)c1ccc(O)c(NC(=S)NC(=O)CCc2ccccc2)c1
d. CCN(c1ccccc1)S(=O)(=O)c1ccc(C(=O)Oc2ccc(C(C)=O)cc2)cc1
Answer: b. COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCOCC1
COC(=O)C1=C(c2ccc(OC)c(OC)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCOCC1
methyl (1R,5S)-3-(3,4-dimethoxyphenyl)-8-(morpholine-4-carbonyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate