Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -51.898\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CS(=O)(=O)N(CC(=O)NCc1cccnc1)C1CCCCC1
b) Cc1cc(OCC(=O)Nc2ccccn2)c2c(C)c(C)c(=O)oc2c1
c) CC(C)(C)CN1C(N)=NC[C@@H]1Cc1ccc(O)cc1
d) N#Cc1ccc(C2=CC(=O)C[C@H](c3ccc(Cl)cc3)C2)cc1
e) Cc1ccc(CN2CCN(/N=C/c3ccc(C(=O)O)cc3)CC2)c(C)c1
Answer: d. N#Cc1ccc(C2=CC(=O)C[C@H](c3ccc(Cl)cc3)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N#Cc1ccc(C2=CC(=O)C[C@H](c3ccc(Cl)cc3)C2)cc1
N#Cc1ccc(C2=CC(=O)C[C@H](c3ccc(Cl)cc3)C2)cc1
4-[(5R)-5-(4-chlorophenyl)-3-oxocyclohexen-1-yl]benzonitrile