Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 13.602\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. COc1cccc(C(=O)Nc2cnc(NC(=O)c3ccco3)cc2C)c1
b. CCN(CC)S(=O)(=O)c1ccc(Cl)c(NC2=NCCCCC2)c1
c. COC(=O)C1=C(C)NC(=O)NC1c1ccc(N2CCC(c3ccccc3)=N2)cc1
d. O=c1[nH]c(CN2CCN(C/C=C/c3ccccc3)CC2)nc2cc(Cl)ccc12
Answer: c. COC(=O)C1=C(C)NC(=O)NC1c1ccc(N2CCC(c3ccccc3)=N2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(C)NC(=O)NC1c1ccc(N2CCC(c3ccccc3)=N2)cc1
COC(=O)C1=C(C)NC(=O)NC1c1ccc(N2CCC(c3ccccc3)=N2)cc1
methyl 6-methyl-2-oxo-4-[4-(5-phenyl-3,4-dihydropyrazol-2-yl)phenyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate