Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -21.178\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(C(=O)N(CN2CCCC2=O)c2nccs2)cc1OC
b. COc1ccc(S(=O)(=O)Nc2cc(C(=O)NC3CCCCCC3)ccc2N2CCOCC2)cc1
c. CNC(=O)c1cc(C(=O)c2ccc(C(F)(F)F)cc2F)c[nH]1
d. COc1cc(-c2nc3cnccn3c2Nc2ccc(C)cc2)ccc1O
e. COc1ccc(-c2csc3nc(-c4ccccc4F)oc(=O)c23)cc1
Answer: b. COc1ccc(S(=O)(=O)Nc2cc(C(=O)NC3CCCCCC3)ccc2N2CCOCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)Nc2cc(C(=O)NC3CCCCCC3)ccc2N2CCOCC2)cc1
COc1ccc(S(=O)(=O)Nc2cc(C(=O)NC3CCCCCC3)ccc2N2CCOCC2)cc1
N-cycloheptyl-3-[(4-methoxyphenyl)sulfonylamino]-4-morpholin-4-ylbenzamide