Task: Answer the multiple choice question.
Query: Which drug has a 8.636\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
[a] COc1ccc(CNC(=O)[C@@H]2CC=C[C@@H]3CCN(C4CC4)C(=O)[C@@H]32)cc1
[b] O=C(O)Cc1ccc2oc(-c3ccccn3)nc2c1
[c] CCOC(=O)C(Cc1ccc(NC(=O)/C(=C\c2ccccc2)NC(=O)c2ccccc2)cc1)N1C(=O)c2ccccc2C1=O
Answer: a. COc1ccc(CNC(=O)[C@@H]2CC=C[C@@H]3CCN(C4CC4)C(=O)[C@@H]32)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)[C@@H]2CC=C[C@@H]3CCN(C4CC4)C(=O)[C@@H]32)cc1
COc1ccc(CNC(=O)[C@@H]2CC=C[C@@H]3CCN(C4CC4)C(=O)[C@@H]32)cc1
(4aS,8R,8aS)-2-cyclopropyl-N-[(4-methoxyphenyl)methyl]-1-oxo-3,4,4a,7,8,8a-hexahydroisoquinoline-8-carboxamide