Problem statement: Answer the MCQ question.
Question: Which compound has a 10.758\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) C/C(=N\NC(=O)CNc1ccccc1)c1ccccc1
b.) Cc1ccccc1NC(=O)CSc1nnc(C)c(=O)[nH]1
c.) CCOC(=O)Cc1csc(NC(=O)CCNS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)n1
d.) O=C(Nc1ccn(Cc2c(F)c(F)cc(F)c2F)n1)c1ccc(COc2cc(Cl)ccc2Cl)o1
e.) COc1cccc(/C=C/C(=O)Nc2ccc(OC)nc2)c1
Answer: c. CCOC(=O)Cc1csc(NC(=O)CCNS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)Cc1csc(NC(=O)CCNS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)n1
CCOC(=O)Cc1csc(NC(=O)CCNS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)n1
ethyl 2-[2-[3-[(2-oxo-3,4-dihydro-1H-quinolin-6-yl)sulfonylamino]propanoylamino]-1,3-thiazol-4-yl]acetate