Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -53.540\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCOc1ccc(S(=O)(=O)NCCC(=O)NC2CCCCC2)cc1
(b) CCN1CCCC1Cn1cnc2c([nH]c3cc(OC)ccc32)c1=O
(c) Cc1cccc(NC(=O)CCS(=O)(=O)c2ccc(Cl)cc2)c1
(d) C#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=Cc5oncc5C[C@]4(C)[C@H]3CC[C@@]21C
(e) Cl.O=C(O)CCN1CCc2ccccc2C1c1cccs1
Answer: b. CCN1CCCC1Cn1cnc2c([nH]c3cc(OC)ccc32)c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN1CCCC1Cn1cnc2c([nH]c3cc(OC)ccc32)c1=O
CCN1CCCC1Cn1cnc2c([nH]c3cc(OC)ccc32)c1=O
3-[(1-ethylpyrrolidin-2-yl)methyl]-7-methoxy-5H-pyrimido[5,4-b]indol-4-one