Problem statement: Answer the multiple-choice question.
Question: Which compound has a -22.642\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: CCC(C)[C@H]1CN=C(N)N1CCc1cccc(F)c1
b: CC(=O)c1ccccc1NC(=O)COC(=O)Cc1cccc(C(F)(F)F)c1
c: CCCN(CCC)CCCNC(=O)c1ccc2c(Cl)c3c(nc2c1)CCC3
d: O=C(c1ccsc1)N1CCCC(N2CCN(c3cccc(C(F)(F)F)c3)CC2)C1
e: C(=N/c1nccs1)\c1cccnc1
Answer: b. CC(=O)c1ccccc1NC(=O)COC(=O)Cc1cccc(C(F)(F)F)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(=O)c1ccccc1NC(=O)COC(=O)Cc1cccc(C(F)(F)F)c1
CC(=O)c1ccccc1NC(=O)COC(=O)Cc1cccc(C(F)(F)F)c1
[2-(2-acetylanilino)-2-oxoethyl] 2-[3-(trifluoromethyl)phenyl]acetate