Task: Answer the multiple-choice question.
Question: Which drug has a 21.960\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CN(C(=O)C1CCN(S(=O)(=O)c2cccc3nonc23)CC1)C1CCCCC1
b. Cc1cccc(NC(=O)CSc2nc(=O)n(CCCN3CCOCC3)c3c2CCCC3)c1
c. CCN(CC)S(=O)(=O)c1cc(NC(=O)CN2C(=O)NC3(CCCc4ccccc43)C2=O)ccc1C
d. CN(c1ccccc1)S(=O)(=O)c1ccc(C(=O)NNC(=O)c2ccccc2)cc1
e. O=C(CNC(=O)[C@@H]1Cc2ccccc2CN1)Nc1ccc2c(c1)OCO2
Answer: e. O=C(CNC(=O)[C@@H]1Cc2ccccc2CN1)Nc1ccc2c(c1)OCO2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CNC(=O)[C@@H]1Cc2ccccc2CN1)Nc1ccc2c(c1)OCO2
O=C(CNC(=O)[C@@H]1Cc2ccccc2CN1)Nc1ccc2c(c1)OCO2
(3S)-N-[2-(1,3-benzodioxol-5-ylamino)-2-oxoethyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxamide