Problem statement: Answer the multiple-choice question.
Question: Which compound has a -27.714\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a.) COP(=O)(OC)C(Nc1cc(Cl)cc(Cl)c1)c1cccc(O)c1
b.) COc1cccc(N2CCN(CC(=O)Nc3ccc(SC(F)F)cc3)CC2)c1
c.) O=S(=O)(c1ccc(F)cc1)n1ccc(-c2cnc(-c3ccccc3)s2)n1
d.) COC(=O)c1ccc(CNC(=O)C2CCC(=O)N(CCc3ccccc3)C2)cc1
Answer: b. COc1cccc(N2CCN(CC(=O)Nc3ccc(SC(F)F)cc3)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(N2CCN(CC(=O)Nc3ccc(SC(F)F)cc3)CC2)c1
COc1cccc(N2CCN(CC(=O)Nc3ccc(SC(F)F)cc3)CC2)c1
N-[4-(difluoromethylsulfanyl)phenyl]-2-[4-(3-methoxyphenyl)piperazin-1-yl]acetamide