Problem statement: Answer the MCQ question.
Question: Which drug has a -11.893\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCn1cc(C(=O)NC(C)C2CC3CCC2C3)cn1
b) Cc1cccc(C(=O)NCCCNC(=O)c2cccc(C)c2)c1
c) CCC(C)NC(=O)/C=C/c1ccc(S(=O)(=O)NCc2ccco2)cc1
d) CCOc1ccccc1N(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NCC1CCCO1)c1ccc2ncccc2c1
e) CCCCNC(=S)N1CCN(c2ccc(C(C)=O)cc2)CC1
Answer: e. CCCCNC(=S)N1CCN(c2ccc(C(C)=O)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCNC(=S)N1CCN(c2ccc(C(C)=O)cc2)CC1
CCCCNC(=S)N1CCN(c2ccc(C(C)=O)cc2)CC1
4-(4-acetylphenyl)-N-butylpiperazine-1-carbothioamide