Task: Answer the multiple-choice question.
Query: Which drug has a 8.083\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) Cc1cc(N2CCN(Cc3cn(C)nc3-c3ccccc3F)CC2)cc(C)n1
b.) CCCCN(c1ccc(C(=O)OC)cc1)S(=O)(=O)c1ccccc1
c.) Cc1cccc2cc(CN(Cc3ccccc3)C(=S)NCCCN(C)C)c(=O)[nH]c12
d.) CCc1noc(C)c1C(=O)N1CCN(S(=O)(=O)c2c(C)cc(C)cc2C)CC1
e.) COc1cc(OC)cc(-c2cc3ccc(OC)cc3cn2)c1
Answer: d. CCc1noc(C)c1C(=O)N1CCN(S(=O)(=O)c2c(C)cc(C)cc2C)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCc1noc(C)c1C(=O)N1CCN(S(=O)(=O)c2c(C)cc(C)cc2C)CC1
CCc1noc(C)c1C(=O)N1CCN(S(=O)(=O)c2c(C)cc(C)cc2C)CC1
(3-ethyl-5-methyl-1,2-oxazol-4-yl)-[4-(2,4,6-trimethylphenyl)sulfonylpiperazin-1-yl]methanone