Problem statement: Answer the multiple-choice question.
Query: Which compound has a -5.085\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C1Cc2ccccc2C(=O)N1OCc1ccc(Cl)cc1Cl
b. COc1cccc(CC2(CO)CCCN(Cc3ccc4c(c3)OCCO4)C2)c1
c. O=C(Nc1cccc(Cl)c1)Nn1cnnc1
d. CC(C)c1ccc(NC(=S)N2CCN(Cc3ccccc3)CC2)cc1
e. Cc1cccc(OS(=O)(=O)NC(=O)OCC2CCCN3CCCCC23)c1
Answer: b. COc1cccc(CC2(CO)CCCN(Cc3ccc4c(c3)OCCO4)C2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CC2(CO)CCCN(Cc3ccc4c(c3)OCCO4)C2)c1
COc1cccc(CC2(CO)CCCN(Cc3ccc4c(c3)OCCO4)C2)c1
[1-(2,3-dihydro-1,4-benzodioxin-6-ylmethyl)-3-[(3-methoxyphenyl)methyl]piperidin-3-yl]methanol