Problem statement: Answer the multiple-choice question.
Query: Which drug has a 14.276\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CCOC(=O)Cc1c(C)[nH]c(=S)[nH]c1=O
[b] CC(C)(C)c1ccc(C(=O)NCC(=O)OCCN2C(=O)c3ccccc3C2=O)cc1
[c] COc1ccc(CCNC(=O)c2cc(-c3ccccc3)on2)cc1OC
[d] COc1cc(/C=C/[N+](=O)[O-])ccc1OC(=O)c1cc2ccccc2oc1=O
[e] O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4F)CC3)n2n1
Answer: e. O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4F)CC3)n2n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4F)CC3)n2n1
O=C1CCCN1CCCNc1ccc2nnc(CCC(=O)N3CCN(c4ccccc4F)CC3)n2n1
1-[3-[[3-[3-[4-(2-fluorophenyl)piperazin-1-yl]-3-oxopropyl]-[1,2,4]triazolo[4,3-b]pyridazin-6-yl]amino]propyl]pyrrolidin-2-one