Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 0.459\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CCc1ccccc1-n1ncc(C(=O)Nc2ccccc2OC)c1C
b. O=C(O)/C=C/c1ccc(S(=O)(=O)N(CCO)CCO)cc1
c. Cc1cc(C(=O)NNC(=S)Nc2ccccc2)nn1C
d. COC(=O)Cn1ncc(N2C3CC(CC(C)(C)C3)C2C)c(Cl)c1=O
e. CN(c1ccc(C(=O)N2CCN(c3ccccc3F)CC2)cc1)S(=O)(=O)c1ccccc1
Answer: d. COC(=O)Cn1ncc(N2C3CC(CC(C)(C)C3)C2C)c(Cl)c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)Cn1ncc(N2C3CC(CC(C)(C)C3)C2C)c(Cl)c1=O
COC(=O)Cn1ncc(N2C3CC(CC(C)(C)C3)C2C)c(Cl)c1=O
methyl 2-[5-chloro-6-oxo-4-(3,3,7-trimethyl-6-azabicyclo[3.2.1]octan-6-yl)pyridazin-1-yl]acetate