Problem statement: Answer the MCQ question.
Query: Which compound has a -8.146\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccc(NC(=O)CN2CCN(c3ccc(F)cc3)CC2)cc1
[b] Cc1ccc(C(=O)COc2ccc(C)cc2N2C(=O)CCCC2=O)cc1
[c] CS(=O)(=O)c1sc(C(=O)NC(=S)Nc2ccc(OC(F)(F)F)cc2)c2c1C=CCC2
[d] CC1CCCC(NC(=O)COC(=O)COc2ccc(Cl)cc2)C1C
[e] O=C(NCc1ccccc1F)C1CCCN1C(=O)Nc1ccc(Cl)cc1
Answer: b. Cc1ccc(C(=O)COc2ccc(C)cc2N2C(=O)CCCC2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(C(=O)COc2ccc(C)cc2N2C(=O)CCCC2=O)cc1
Cc1ccc(C(=O)COc2ccc(C)cc2N2C(=O)CCCC2=O)cc1
1-[5-methyl-2-[2-(4-methylphenyl)-2-oxoethoxy]phenyl]piperidine-2,6-dione