Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -14.360\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a NC(=O)C1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1
b COc1ccccc1-n1cnnc1SC(C)C(=O)NCC1CCCO1
c O=C(CCc1nc2ccccc2c(=O)[nH]1)N1CCN(S(=O)(=O)c2ccc(Cl)c(C(F)(F)F)c2)CC1
d O=C(NCC1CCCN1S(=O)(=O)c1cccs1)c1ccc(Cl)cc1
e CN1CCN(CC(O)COc2ccccc2)CC1
Answer: d. O=C(NCC1CCCN1S(=O)(=O)c1cccs1)c1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCC1CCCN1S(=O)(=O)c1cccs1)c1ccc(Cl)cc1
O=C(NCC1CCCN1S(=O)(=O)c1cccs1)c1ccc(Cl)cc1
4-chloro-N-[(1-thiophen-2-ylsulfonylpyrrolidin-2-yl)methyl]benzamide