Problem statement: Answer the multiple-choice question.
Query: Which compound has a 3.778\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) COc1cc(OC)cc(C(=O)N[C@H](C(=O)OCC(=O)Nc2ccc(C(N)=O)cc2)C(C)C)c1
b) O=C(c1ccc2c(c1)N(Cc1ccc(F)cc1)CCS2)N1CCC2(CC1)OCCO2
c) COc1ccc(N2CCN(C(=O)CSc3nc4c(c(=O)n(C)c(=O)n4C)n3C(C)C)CC2)cc1
d) OCCC1CN(CCCc2ccccc2)CCN1Cc1ccc(F)cc1
Answer: b. O=C(c1ccc2c(c1)N(Cc1ccc(F)cc1)CCS2)N1CCC2(CC1)OCCO2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccc2c(c1)N(Cc1ccc(F)cc1)CCS2)N1CCC2(CC1)OCCO2
O=C(c1ccc2c(c1)N(Cc1ccc(F)cc1)CCS2)N1CCC2(CC1)OCCO2
1,4-dioxa-8-azaspiro[4.5]decan-8-yl-[4-[(4-fluorophenyl)methyl]-2,3-dihydro-1,4-benzothiazin-6-yl]methanone