Problem statement: Answer the multiple-choice question.
Question: Which drug has a -9.272\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CCc1cccc(NC(=O)c2cc(S(=O)(=O)N(C)C)ccc2N2CCCC2)c1
b.) O=C(c1cc(Br)ccc1Cl)N1CCN(c2ccc(N3CCOCC3)nn2)CC1
c.) COc1cccc(OC)c1C(=O)NC(=S)NCc1ccccc1
d.) O=C(NNc1nc(-c2ccccc2)c2cc(Br)ccc2n1)c1ccc(S(=O)(=O)N2CCOCC2)cc1
e.) O=C(Nc1ccc(-c2cn3ccccc3n2)cc1)c1ccco1
Answer: a. CCc1cccc(NC(=O)c2cc(S(=O)(=O)N(C)C)ccc2N2CCCC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCc1cccc(NC(=O)c2cc(S(=O)(=O)N(C)C)ccc2N2CCCC2)c1
CCc1cccc(NC(=O)c2cc(S(=O)(=O)N(C)C)ccc2N2CCCC2)c1
5-(dimethylsulfamoyl)-N-(3-ethylphenyl)-2-pyrrolidin-1-ylbenzamide