Problem statement: Answer the multiple choice question.
Question: Which compound has a -1.469\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CN(CC(=O)Nc1ccccc1Cl)C(=O)c1cccc(-n2cccc2)c1
b) NC(=O)c1nsc(C(=O)N(c2ccc(F)cc2)C(C(=O)NCC2CCCO2)c2ccc3ncccc3c2)c1N
c) c1cncc(-c2nc(N3CCOCC3)c3ccccc3n2)c1
d) COc1ccc(Br)cc1C1CC(=O)C(C)C(c2cc(Br)ccc2OC)N1
e) O=C(NNC(=O)c1ccc(-c2ccccc2)cc1)Nc1ccccc1F
Answer: b. NC(=O)c1nsc(C(=O)N(c2ccc(F)cc2)C(C(=O)NCC2CCCO2)c2ccc3ncccc3c2)c1N
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
NC(=O)c1nsc(C(=O)N(c2ccc(F)cc2)C(C(=O)NCC2CCCO2)c2ccc3ncccc3c2)c1N
NC(=O)c1nsc(C(=O)N(c2ccc(F)cc2)C(C(=O)NCC2CCCO2)c2ccc3ncccc3c2)c1N
4-amino-5-N-(4-fluorophenyl)-5-N-[2-oxo-2-(oxolan-2-ylmethylamino)-1-quinolin-6-ylethyl]-1,2-thiazole-3,5-dicarboxamide