Problem statement: Answer the MCQ question.
Question: Which drug has a 18.557\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(Cn2nnnc2C(c2cc3cccc(C)c3[nH]c2=O)N2CCOCC2)cc1
(b) CC1CCCN(S(=O)(=O)c2ccc(C(=O)Nc3nnc(-c4ccncc4)o3)cc2)C1
(c) Nc1c(C(=O)O)cnc2nc(N3CCOCC3)nn12
(d) CN1C2CCC1CC(NC(=O)c1cccc(C(F)(F)F)c1)C2
(e) O=C(O)c1ccc(-c2noc(-c3ccccc3C(F)(F)F)n2)cc1
Answer: e. O=C(O)c1ccc(-c2noc(-c3ccccc3C(F)(F)F)n2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(O)c1ccc(-c2noc(-c3ccccc3C(F)(F)F)n2)cc1
O=C(O)c1ccc(-c2noc(-c3ccccc3C(F)(F)F)n2)cc1
4-[5-[2-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl]benzoic acid