Task: Answer the multiple choice question.
Query: Which compound has a -21.999\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
(a) O=C(CN1CCN(Cc2ccccc2)CC1)NC(c1ccccc1)c1ccccc1.O=C(O)C(=O)O
(b) COc1ccc(C2(C)NC(=O)N(CC(=O)NC(C)c3ccc(CC(C)C)cc3)C2=O)cc1
(c) COC(=O)CCN1CCC(c2cc(-c3cccc(C(F)(F)F)c3)n[nH]2)CC1
Answer: c. COC(=O)CCN1CCC(c2cc(-c3cccc(C(F)(F)F)c3)n[nH]2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)CCN1CCC(c2cc(-c3cccc(C(F)(F)F)c3)n[nH]2)CC1
COC(=O)CCN1CCC(c2cc(-c3cccc(C(F)(F)F)c3)n[nH]2)CC1
methyl 3-[4-[3-[3-(trifluoromethyl)phenyl]-1H-pyrazol-5-yl]piperidin-1-yl]propanoate