Problem statement: Answer the MCQ question.
Question: Which compound has a -3.089\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COCCn1c(SCc2cccc(F)c2)nc2cc(C(=O)OC)ccc2c1=O
b.) COC(=O)Oc1ccc(/C=N/NC(=O)CN(c2ccccc2Cl)S(C)(=O)=O)cc1OC
c.) CCS(=O)(=O)N1Cc2ccccc2CC1C(=O)Nc1nc(C)cs1
d.) CCOC(=O)c1cnc(SC)nc1Oc1cccc(NS(=O)(=O)c2ccc(Cl)cc2)c1
e.) CNC(=S)N1N=C2c3ccccc3CCC2C1c1ccccc1Cl
Answer: d. CCOC(=O)c1cnc(SC)nc1Oc1cccc(NS(=O)(=O)c2ccc(Cl)cc2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)c1cnc(SC)nc1Oc1cccc(NS(=O)(=O)c2ccc(Cl)cc2)c1
CCOC(=O)c1cnc(SC)nc1Oc1cccc(NS(=O)(=O)c2ccc(Cl)cc2)c1
4-chloro-N-[3-(5-ethoxycarbonyl-2-methylsulfanylpyrimidin-4-yl)oxyphenyl]benzenesulfonamide