Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -0.778\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) O=C(Nc1ccc(NC(=O)c2ccco2)c(Cl)c1)c1ccc2c(c1)OCCO2
(b) COc1cc(S(=O)(=O)N(Cc2cccc(OC)c2OC)CC2CCCO2)ccc1-n1cnnn1
(c) CCc1c(C(=O)N/N=C/c2cccs2)nnn1-c1nonc1N
(d) CC(C)CN1C(=O)c2ccc(C(=O)Nc3nccs3)cc2C1=O
(e) CCC(=O)Nc1c2c(nn1-c1cccc(Cl)c1)CSC2
Answer: e. CCC(=O)Nc1c2c(nn1-c1cccc(Cl)c1)CSC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCC(=O)Nc1c2c(nn1-c1cccc(Cl)c1)CSC2
CCC(=O)Nc1c2c(nn1-c1cccc(Cl)c1)CSC2
N-[2-(3-chlorophenyl)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]propanamide