Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 5.035\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccc(C(CNC(=O)C(=O)Nc2ccc3c(c2)OCO3)N2CCN(C)CC2)cc1
b) COc1ccccc1C1C(C(=O)c2ccco2)=C(O)C(=O)N1c1cc(C)on1
c) COc1cccc(CN2CCN(C(=O)C3CCC(=O)N(C4CCCC4)C3)CC2)c1
d) O=C(CCC1CCCN(C(=O)c2ccc(F)c(F)c2)C1)N1CCN(c2ccccn2)CC1
e) O=C1N(c2cccc3ccccc23)C(c2ccccc2)N2CCCN12
Answer: c. COc1cccc(CN2CCN(C(=O)C3CCC(=O)N(C4CCCC4)C3)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CN2CCN(C(=O)C3CCC(=O)N(C4CCCC4)C3)CC2)c1
COc1cccc(CN2CCN(C(=O)C3CCC(=O)N(C4CCCC4)C3)CC2)c1
1-cyclopentyl-5-[4-[(3-methoxyphenyl)methyl]piperazine-1-carbonyl]piperidin-2-one