Task: Answer the multiple-choice question.
Question: Which drug exhibits a -16.817\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCOCCCN(CCC#N)C(=O)C1CCN(S(=O)(=O)c2ccc(-n3cnnn3)cc2)CC1
b) CC(=O)[O-].[K+].c1ccc2c(c1)OCCOCCOc1ccccc1OCCOCCO2
c) CCCCCN(C(=O)NC(=O)Nc1nncs1)S(C)(=O)=O
d) COCCn1cnnc1SCC(=O)Nc1cccc(S(=O)(=O)N2CCCCCC2)c1
e) COc1ccc(C2/C(=C(/O)c3ccc(F)cc3)C(=O)C(=O)N2c2ccccn2)cc1OC
Answer: d. COCCn1cnnc1SCC(=O)Nc1cccc(S(=O)(=O)N2CCCCCC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCn1cnnc1SCC(=O)Nc1cccc(S(=O)(=O)N2CCCCCC2)c1
COCCn1cnnc1SCC(=O)Nc1cccc(S(=O)(=O)N2CCCCCC2)c1
N-[3-(azepan-1-ylsulfonyl)phenyl]-2-[[4-(2-methoxyethyl)-1,2,4-triazol-3-yl]sulfanyl]acetamide