Problem statement: Answer the multiple-choice question.
Query: Which drug has a 12.459\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CC(=O)Nc1ccc(NC(=O)CSc2ncn[nH]2)cc1
b Cc1nnc(NC(=O)CC(NC(=O)C(F)(F)F)c2ccccc2)s1
c COc1ccc(NC(=S)N2CCN(CCN3C(=O)c4cccc5cccc(c45)C3=O)CC2)cc1
d COc1cccc(C(=O)Nc2cc3c4c(c2)CC(=O)N4CCC3)c1
e CN(C)/C=N/c1c(C#N)cnn1-c1ccc(C(F)(F)F)cn1
Answer: d. COc1cccc(C(=O)Nc2cc3c4c(c2)CC(=O)N4CCC3)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(C(=O)Nc2cc3c4c(c2)CC(=O)N4CCC3)c1
COc1cccc(C(=O)Nc2cc3c4c(c2)CC(=O)N4CCC3)c1
5-methoxy-N-(2-oxo-1-azatricyclo[6.3.1.04,12]dodeca-4,6,8(12)-trien-6-yl)benzamide