Problem statement: Answer the multiple-choice question.
Question: Which drug has a 5.686\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: Cc1ccc(C2(C)NC(=O)N(CC(=O)c3ccc(Cl)s3)C2=O)cc1
b: Cl.c1ccc(-c2cc(-c3ccncc3)nc3ccc4ccccc4c23)cc1
c: COc1cc2c(cc1OC)C(C)=NC1(CCCCC1)C2.O=C(O)c1ccccc1O
d: O=C(O)c1ccc(CNC(=O)C2CCCN2C(=O)OCc2ccccc2)cc1
e: Cc1nc2ccc(NC(=O)CS(=O)(=O)c3ccccc3)cc2s1
Answer: c. COc1cc2c(cc1OC)C(C)=NC1(CCCCC1)C2.O=C(O)c1ccccc1O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(C)=NC1(CCCCC1)C2.O=C(O)c1ccccc1O
COc1cc2c(cc1OC)C(C)=NC1(CCCCC1)C2.O=C(O)c1ccccc1O
6,7-dimethoxy-1-methylspiro[4H-isoquinoline-3,1'-cyclohexane];2-hydroxybenzoic acid