Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -47.190\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C1c2ccccc2C(=O)N1c1ncc(Cc2ccc(Cl)cc2)s1
b) O=C(N/N=C/C=C/c1ccco1)c1cccc([N+](=O)[O-])c1
c) COc1ccccc1CN1CCC(n2nccc2NC(=O)c2ccccc2Cl)CC1
d) CCOC(=O)N1CCN(C(=O)COC(=O)C2CCN(S(=O)(=O)c3c(C)c(C)cc(C)c3C)CC2)CC1
e) Nc1nc2c(ccc3ccccc32)s1
Answer: c. COc1ccccc1CN1CCC(n2nccc2NC(=O)c2ccccc2Cl)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1CN1CCC(n2nccc2NC(=O)c2ccccc2Cl)CC1
COc1ccccc1CN1CCC(n2nccc2NC(=O)c2ccccc2Cl)CC1
2-chloro-N-[2-[1-[(2-methoxyphenyl)methyl]piperidin-4-yl]pyrazol-3-yl]benzamide