Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -7.740\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1ccc(NC(=O)N2CCC(n3nnc4cc(C)ccc43)CC2)cc1
b COc1cccc2cc(-c3nnc(SCC(=O)Nc4nc(C)cs4)n3C)oc12
c Cc1cc(=O)oc2cc(OCc3ccccc3)ccc12
d Cc1noc(C)c1COC(=O)c1cnc(Cl)c(Cl)c1
e CCn1c(SCc2ccccc2F)nnc1-c1ccncc1
Answer: a. COc1ccc(NC(=O)N2CCC(n3nnc4cc(C)ccc43)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)N2CCC(n3nnc4cc(C)ccc43)CC2)cc1
COc1ccc(NC(=O)N2CCC(n3nnc4cc(C)ccc43)CC2)cc1
N-(4-methoxyphenyl)-4-(5-methylbenzotriazol-1-yl)piperidine-1-carboxamide