Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -16.689\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCCn1c(N2CCN(C(=O)N3CCCCC3)CC2)nc2ccccc21.Cl
b) Cn1c(=O)cc(N2CCCCC2)[nH]c1=O
c) CCOC(=O)N1CCN(C(=O)c2cn(C)c3ccc(S(=O)(=O)N(C)C4CCCCC4)cc3c2=O)CC1
d) CCOC(=O)c1c(NC(=S)Nc2cccc(C)c2)sc2c1CC(C)(C)SC2
e) CNc1nc(Nc2ccc([N+](=O)[O-])cc2)nc(OCC(F)(F)F)n1
Answer: c. CCOC(=O)N1CCN(C(=O)c2cn(C)c3ccc(S(=O)(=O)N(C)C4CCCCC4)cc3c2=O)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(C(=O)c2cn(C)c3ccc(S(=O)(=O)N(C)C4CCCCC4)cc3c2=O)CC1
CCOC(=O)N1CCN(C(=O)c2cn(C)c3ccc(S(=O)(=O)N(C)C4CCCCC4)cc3c2=O)CC1
ethyl 4-[6-[cyclohexyl(methyl)sulfamoyl]-1-methyl-4-oxoquinoline-3-carbonyl]piperazine-1-carboxylate