Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 15.456\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCC(=O)N(CCc1ccccc1)Cc1cc2cc(OC)ccc2[nH]c1=O
(b) Cc1cc(C(=O)CSc2nc3ccccc3n2C)c(C)n1C
(c) COc1ccc(OC)c(NC(=O)C(=O)c2cn(CC(=O)N3CCCC3)c3ccccc23)c1
(d) CCn1nc(C(=O)NCC(c2cccs2)N2CCOCC2)c2ccccc2c1=O
(e) CCn1ncc([C@@H]2C[C@H]3CN(Cc4ccccc4C)C(=O)[C@]34CCCN24)c1C
Answer: c. COc1ccc(OC)c(NC(=O)C(=O)c2cn(CC(=O)N3CCCC3)c3ccccc23)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OC)c(NC(=O)C(=O)c2cn(CC(=O)N3CCCC3)c3ccccc23)c1
COc1ccc(OC)c(NC(=O)C(=O)c2cn(CC(=O)N3CCCC3)c3ccccc23)c1
N-(2,5-dimethoxyphenyl)-2-oxo-2-[1-(2-oxo-2-pyrrolidin-1-ylethyl)indol-3-yl]acetamide