Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 9.282\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CC12CCC(=O)N1C(C(=O)N1CCN(S(=O)(=O)c3cccc(C(F)(F)F)c3)CC1)CS2
b. COCCn1c(Cc2cccn2C)nnc1SCC(=O)NCc1ccc2c(c1)OCO2
c. CCN(CC)c1ccc(C(=O)NNC(=O)CN2C(=O)NC(C)(c3ccccc3)C2=O)cc1
d. O=C(c1ccco1)n1c(=S)nc2ccccn21
e. COc1ccc(C)cc1NC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)c(=O)n2C
Answer: c. CCN(CC)c1ccc(C(=O)NNC(=O)CN2C(=O)NC(C)(c3ccccc3)C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN(CC)c1ccc(C(=O)NNC(=O)CN2C(=O)NC(C)(c3ccccc3)C2=O)cc1
CCN(CC)c1ccc(C(=O)NNC(=O)CN2C(=O)NC(C)(c3ccccc3)C2=O)cc1
4-(diethylamino)-N'-[2-(4-methyl-2,5-dioxo-4-phenylimidazolidin-1-yl)acetyl]benzohydrazide