Problem statement: Answer the MCQ question.
Question: Which compound has a 19.290\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COC(=O)[C@@H]1CCCN1Cc1c(C(=O)N2CCCCC2)nc2c(C)cccn12
b) Cc1ccc(Cl)cc1N1CCN(C(=O)COc2ccc3c(c2)CCC3)CC1
c) Cn1c(-c2ccc3c(c2)OCO3)cnc1N
d) COCCn1c(SCC(=O)Nc2ccc(OC)cc2)nc2c(oc3ccccc32)c1=O
e) CC(C)n1ncc2c(C(=O)N3CCN(c4ccccc4)CC3)cc(-c3ccccc3)nc21
Answer: e. CC(C)n1ncc2c(C(=O)N3CCN(c4ccccc4)CC3)cc(-c3ccccc3)nc21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)n1ncc2c(C(=O)N3CCN(c4ccccc4)CC3)cc(-c3ccccc3)nc21
CC(C)n1ncc2c(C(=O)N3CCN(c4ccccc4)CC3)cc(-c3ccccc3)nc21
(4-phenylpiperazin-1-yl)-(6-phenyl-1-propan-2-ylpyrazolo[3,4-b]pyridin-4-yl)methanone