Task: Answer the multiple choice question.
Query: Which drug has a -8.256\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCC(C)C(=O)Nc1nc(C)c(-c2csc(Nc3ccccc3OC)n2)s1
(b) COC(=O)c1ccc2c(=O)n(Cc3ccc4c(c3)OCO4)c(SCC(=O)N3CCCC3)nc2c1
(c) COC(=O)[C@@H]1[C@@H](C)OC(=O)N[C@H]1c1ccccc1
(d) OC(COc1ccccc1)CN1CCN(C(c2ccccc2)c2ccccc2)CC1
(e) O=C(NCCc1cccc(F)c1)C1CCCN(c2nc3ccccc3s2)C1
Answer: c. COC(=O)[C@@H]1[C@@H](C)OC(=O)N[C@H]1c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)[C@@H]1[C@@H](C)OC(=O)N[C@H]1c1ccccc1
COC(=O)[C@@H]1[C@@H](C)OC(=O)N[C@H]1c1ccccc1
methyl (4R,5S,6R)-6-methyl-2-oxo-4-phenyl-1,3-oxazinane-5-carboxylate