Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -16.884\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1ccc(NC2=C(Cl)C(=O)N(C3CCCCC3)C2=O)cc1
b) COC(=O)c1ccc(NC(=O)CCN2CCN(Cc3ccccc3)CC2)cc1
c) CCNC(=S)NNC(=O)C1CCCCC1
d) Cc1ccc(N=C/C(C(=O)C(F)(F)F)=C(\O)c2ccco2)cc1Cl
e) O=C(Nc1ccc(Cl)c(Cl)c1)OCCNC(=O)c1ccncc1
Answer: b. COC(=O)c1ccc(NC(=O)CCN2CCN(Cc3ccccc3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(NC(=O)CCN2CCN(Cc3ccccc3)CC2)cc1
COC(=O)c1ccc(NC(=O)CCN2CCN(Cc3ccccc3)CC2)cc1
methyl4-[3-(4-benzylpiperazin-1-yl)propanoylamino]benzoate