Problem statement: Answer the multiple choice question.
Question: Which drug has a 8.530\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccc(CCn2c(-c3ccccc3)nc3c(c(=O)c4ccccc4n3C)c2=O)cc1
[b] CN1CC2(Cc3c1ccc1ccccc31)C(=O)OC(C)(C)OC2=O
[c] O=[N+]([O-])c1ccc(O)c(C=Nc2ccc3nc(-c4ccccc4)[nH]c3c2)c1
[d] COc1ccc(/C=C(/NC(=O)c2ccccc2)C(=O)NCc2ccco2)cc1
[e] Cc1ccc(C(=O)N2CCCC(N3CCN(c4cccc(C(F)(F)F)c4)CC3)C2)s1
Answer: b. CN1CC2(Cc3c1ccc1ccccc31)C(=O)OC(C)(C)OC2=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1CC2(Cc3c1ccc1ccccc31)C(=O)OC(C)(C)OC2=O
CN1CC2(Cc3c1ccc1ccccc31)C(=O)OC(C)(C)OC2=O
2,2,4'-trimethylspiro[1,3-dioxane-5,2'-1,3-dihydrobenzo[f]quinoline]-4,6-dione