Problem statement: Answer the multiple-choice question.
Question: Which drug has a -27.993\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C(Nc1ccc(Oc2ccc(Br)cc2)cc1)C1=CC=CN2CCS(=O)(=O)N=C12
b.) O=c1[nH]c(CN2CCN(Cc3ccc4c(c3)OCO4)CC2)nc2ccccc12
c.) COc1ccc(C(=O)Nc2cc(C)c3c(=O)oc4ccccc4c3n2)cc1
d.) COc1ccccc1C1c2[nH]c3ccccc3c2C[C@H]2C(=O)N(C3CCN(Cc4ccccc4)CC3)CC(=O)N12
e.) Cc1ccc(/C=C2\C(=O)ON=C2c2ccccc2)o1
Answer: b. O=c1[nH]c(CN2CCN(Cc3ccc4c(c3)OCO4)CC2)nc2ccccc12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=c1[nH]c(CN2CCN(Cc3ccc4c(c3)OCO4)CC2)nc2ccccc12
O=c1[nH]c(CN2CCN(Cc3ccc4c(c3)OCO4)CC2)nc2ccccc12
2-[[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]methyl]-3H-quinazolin-4-one