Task: Answer the multiple choice question.
Question: Which compound exhibits a 17.889\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: Cc1cccn2c(=O)c3cc(C(=O)NCc4ccco4)c(=N)n(CCc4ccccc4)c3nc12
b: COc1ccc(CCN2C(=O)CC(C(N)=O)SC2=Nc2ccc(F)cc2)cc1OC
c: Cc1ccc(NC(=O)c2ccccc2NS(=O)(=O)c2ccc(Cl)s2)cc1
d: NC(=O)CSc1nc(O)cc(=O)n1-c1ccccc1
e: O=C(Nc1nccs1)[C@@H]1CC=C[C@@H]2CCN(Cc3ccccc3)C(=O)[C@@H]21
Answer: e. O=C(Nc1nccs1)[C@@H]1CC=C[C@@H]2CCN(Cc3ccccc3)C(=O)[C@@H]21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1nccs1)[C@@H]1CC=C[C@@H]2CCN(Cc3ccccc3)C(=O)[C@@H]21
O=C(Nc1nccs1)[C@@H]1CC=C[C@@H]2CCN(Cc3ccccc3)C(=O)[C@@H]21
(4aS,8R,8aS)-2-benzyl-1-oxo-N-(1,3-thiazol-2-yl)-3,4,4a,7,8,8a-hexahydroisoquinoline-8-carboxamide