Problem statement: Answer the MCQ question.
Question: Which compound has a -1.807\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1cc(/C=C(/C#N)C(=O)c2c(C)[nH]c3ccccc23)ccc1OCC#N
b.) CCOc1cc(CNc2ccc(CNc3ncn[nH]3)cc2)ccc1OCc1ccccc1
c.) CCOC(=O)C1(Cc2cccc(OC)c2)CCN(Cc2ccc3c(c2)OCCO3)CC1
d.) CC(/C=N/NC(=O)Cc1cccn1C)=C\c1ccccc1
e.) Cc1c(Cl)cccc1NC(=S)N1CCC(C(N)=O)(N2CCCCC2)CC1
Answer: d. CC(/C=N/NC(=O)Cc1cccn1C)=C\c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(/C=N/NC(=O)Cc1cccn1C)=C\c1ccccc1
CC(/C=N/NC(=O)Cc1cccn1C)=C\c1ccccc1
N-[(E)-[(E)-2-methyl-3-phenylprop-2-enylidene]amino]-2-(1-methylpyrrol-2-yl)acetamide