Problem statement: Answer the multiple-choice question.
Question: Which compound has a 0.539\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCOc1ccc(NC(=O)N(CCC(C)C)C2CCN(C(C)=O)CC2)cc1
b) CCc1c2ccccc2nn1-c1ccccc1C(=O)C(C)=O
c) COc1cccc(C(=O)C2CCCN(C(=O)c3ccccc3Cl)C2)c1
d) Cc1ccc(S(=O)(=O)N2CCN(C(C)C(=O)N3CCCc4ccccc43)CC2)cc1
e) CCOC(=O)c1c(NC(=O)CSc2nnc(-c3ccc(OC)cc3)o2)sc2c1CCC2
Answer: d. Cc1ccc(S(=O)(=O)N2CCN(C(C)C(=O)N3CCCc4ccccc43)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(S(=O)(=O)N2CCN(C(C)C(=O)N3CCCc4ccccc43)CC2)cc1
Cc1ccc(S(=O)(=O)N2CCN(C(C)C(=O)N3CCCc4ccccc43)CC2)cc1
1-(3,4-dihydro-2H-quinolin-1-yl)-2-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]propan-1-one