Problem statement: Answer the multiple choice question.
Question: Which compound has a -1.545\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CCOC(=O)CNS(=O)(=O)c1c(C)noc1C
[b] O=C(Nc1cccc(C(=O)N2CCOCC2)c1)c1ccccc1
[c] Cc1ccccc1Oc1ncnc2oc(-c3ccccc3)cc12
[d] COc1ccc(-c2cc(C(=O)NCCN3CCOCC3)c3ccccc3n2)cc1
[e] Cc1cccc(CC2S/C(=N/c3cccc(C)n3)NC2=O)c1
Answer: d. COc1ccc(-c2cc(C(=O)NCCN3CCOCC3)c3ccccc3n2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2cc(C(=O)NCCN3CCOCC3)c3ccccc3n2)cc1
COc1ccc(-c2cc(C(=O)NCCN3CCOCC3)c3ccccc3n2)cc1
2-(4-methoxyphenyl)-N-(2-morpholin-4-ylethyl)quinoline-4-carboxamide