Task: Answer the MCQ question.
Question: Which compound has a -1.639\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a c1ccc2c(CSc3nnc(-c4ccncc4)o3)cccc2c1
b O=C(CN1CCN(Cc2ccccc2)C1=O)NCCCN1CCOCC1
c CCN(CC)S(=O)(=O)c1ccc(Cl)c(NC(=O)COc2ccc(OC)cc2[N+](=O)[O-])c1
d O=C(CCc1nc2ccccc2c(=O)[nH]1)OCC(=O)c1ccc(C2CCCCC2)cc1
e COc1ccc(-c2n[nH]c(C)c2-c2cscn2)c(O)c1
Answer: d. O=C(CCc1nc2ccccc2c(=O)[nH]1)OCC(=O)c1ccc(C2CCCCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCc1nc2ccccc2c(=O)[nH]1)OCC(=O)c1ccc(C2CCCCC2)cc1
O=C(CCc1nc2ccccc2c(=O)[nH]1)OCC(=O)c1ccc(C2CCCCC2)cc1
[2-(4-cyclohexylphenyl)-2-oxoethyl] 3-(4-oxo-3H-quinazolin-2-yl)propanoate