Task: Answer the multiple-choice question.
Question: Which compound has a 8.318\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: O=C(Cc1ccc(S(=O)(=O)N2CCOCC2)s1)NCCOc1ccccc1
b: COc1ccc(-n2c(=O)c3c(C)c(C)sc3n(Cc3ccc(F)cc3)c2=O)c(OC)c1
c: O=C(NC1CC2CCC1C2)C1CCN(S(=O)(=O)c2ccc(-c3nn[nH]n3)cc2)CC1
d: O=C(NCCN1CCOCC1)c1ccc(Cl)cc1O
e: Cc1cc(NC(=O)c2ccccc2)nc2c1c(=O)oc1ccccc12
Answer: b. COc1ccc(-n2c(=O)c3c(C)c(C)sc3n(Cc3ccc(F)cc3)c2=O)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-n2c(=O)c3c(C)c(C)sc3n(Cc3ccc(F)cc3)c2=O)c(OC)c1
COc1ccc(-n2c(=O)c3c(C)c(C)sc3n(Cc3ccc(F)cc3)c2=O)c(OC)c1
3-(2,4-dimethoxyphenyl)-1-[(4-fluorophenyl)methyl]-5,6-dimethylthieno[2,3-d]pyrimidine-2,4-dione