Problem statement: Answer the multiple-choice question.
Query: Which drug has a -12.936\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: COc1ccc(/C(O)=C2/C(=O)C(=O)N(Cc3ccco3)C2c2cccs2)cc1
b: CC(C)=NNc1nc2sc3c(c2c(=O)[nH]1)CC(C)(C)OC3
c: COc1ccc(CCC(=O)NC2CCC(C)CC2)cc1
d: COc1ccc([N+](=O)[O-])c(S(=O)(=O)c2ccc(Cl)cc2)n1
Answer: b. CC(C)=NNc1nc2sc3c(c2c(=O)[nH]1)CC(C)(C)OC3
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)=NNc1nc2sc3c(c2c(=O)[nH]1)CC(C)(C)OC3
CC(C)=NNc1nc2sc3c(c2c(=O)[nH]1)CC(C)(C)OC3
12,12-dimethyl-5-(2-propan-2-ylidenehydrazinyl)-11-oxa-8-thia-4,6-diazatricyclo[7.4.0.02,7]trideca-1(9),2(7),5-trien-3-one