Problem statement: Answer the MCQ question.
Question: Which drug has a -3.671\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1cccc(C(=O)C2CCCN(C(=O)c3ccccc3Cl)C2)c1
b) CCOc1cc(C(=O)NCC(=O)N/N=C/c2sccc2C)cc(OCC)c1OCC
c) COC(=O)CCCC1=CC2=CC(=O)C(C)(OC(=O)c3cccs3)C(=O)C2=CN1C1CCCC1
d) CCOC(=O)C1(CCOc2ccccc2)CCN(CC2CC2)CC1
e) Cc1ccc(S(=O)(=O)N(C)CC(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)cc1
Answer: e. Cc1ccc(S(=O)(=O)N(C)CC(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(S(=O)(=O)N(C)CC(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)cc1
Cc1ccc(S(=O)(=O)N(C)CC(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)cc1
[2-(4-amino-1,3-dimethyl-2,6-dioxopyrimidin-5-yl)-2-oxoethyl] 2-[methyl-(4-methylphenyl)sulfonylamino]acetate