Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a 8.025\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) COc1ccc(S(=O)(=O)N2CCCC2)cc1NC(=O)c1ccccc1F
(b) CCOc1ccc(N2C(=O)C3C(c4ccc(OC)cc4OC)NC(CCSC)(C(=O)OC)C3C2=O)cc1
(c) COc1ccc(CC2(CO)CCN(C(C)Cc3ccc(Cl)cc3)CC2)cc1
(d) OCCC1CN(Cc2ccc3c(c2)CCO3)CCN1C1CCCC1
Answer: b. CCOc1ccc(N2C(=O)C3C(c4ccc(OC)cc4OC)NC(CCSC)(C(=O)OC)C3C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(N2C(=O)C3C(c4ccc(OC)cc4OC)NC(CCSC)(C(=O)OC)C3C2=O)cc1
CCOc1ccc(N2C(=O)C3C(c4ccc(OC)cc4OC)NC(CCSC)(C(=O)OC)C3C2=O)cc1
methyl 1-(2,4-dimethoxyphenyl)-5-(4-ethoxyphenyl)-3-(2-methylsulfanylethyl)-4,6-dioxo-1,2,3a,6a-tetrahydropyrrolo[3,4-c]pyrrole-3-carboxylate