Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a 10.607\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Nc1nonc1-c1noc(CCCOc2ccc(Cl)cc2Cl)n1
b COc1ccc(-c2c(C(C)=O)c(C)nc3sc4c(=O)n(-c5ccc(C)cc5)nnc4c23)cc1
c COc1cc(/C=N/NC(=O)c2cccc3ccccc23)cc(OC)c1O
d CN(C)c1ccc(CNn2cnnc2SCc2ccc(F)cc2)cc1
e Clc1nc(NCc2ccco2)nc(N2CCCCC2)n1
Answer: b. COc1ccc(-c2c(C(C)=O)c(C)nc3sc4c(=O)n(-c5ccc(C)cc5)nnc4c23)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2c(C(C)=O)c(C)nc3sc4c(=O)n(-c5ccc(C)cc5)nnc4c23)cc1
COc1ccc(-c2c(C(C)=O)c(C)nc3sc4c(=O)n(-c5ccc(C)cc5)nnc4c23)cc1
12-acetyl-13-(4-methoxyphenyl)-11-methyl-5-(4-methylphenyl)-8-thia-3,4,5,10-tetrazatricyclo[7.4.0.02,7]trideca-1(13),2(7),3,9,11-pentaen-6-one