Problem statement: Answer the MCQ question.
Question: Which drug has a 0.583\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccc(CN2C(=O)CN=C2Nc2ccc(C)cc2C)cc1.Cl
b) COc1cc(NC(=S)Nc2cccc(Cl)c2Cl)c(OC)cc1Cl
c) COc1ccc(CCNC(=O)Cn2c(=O)n(-c3ccc(F)cc3F)c(=O)c3sccc32)cc1OC
d) CCCCNC(=O)CCn1c(=O)c2ccccc2n(Cc2ccc(F)cc2)c1=O
e) Fc1cc(F)cc(NC(=S)N2CCN(c3ncccn3)CC2)c1
Answer: d. CCCCNC(=O)CCn1c(=O)c2ccccc2n(Cc2ccc(F)cc2)c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCNC(=O)CCn1c(=O)c2ccccc2n(Cc2ccc(F)cc2)c1=O
CCCCNC(=O)CCn1c(=O)c2ccccc2n(Cc2ccc(F)cc2)c1=O
N-butyl-3-[1-[(4-fluorophenyl)methyl]-2,4-dioxoquinazolin-3-yl]propanamide