Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -3.183\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1cc(C2=Nc3ccc(Br)cc3C(c3ccccc3)N2CC(=O)NN)cc(OC)c1OC
b: COC(=O)CCC(=O)NNC(=O)C1CC1(c1ccccc1)c1ccccc1
c: Cc1ccc(S(=O)(=O)N2CCN(C(=O)CSc3nc4ccccc4o3)C2)cc1
d: Clc1ccc(C2CC(c3cccs3)n3ncnc3N2)cc1Cl
e: COC(=O)c1ccc(NCN2C(=O)C3C4CCC(C4)C3C2=O)cc1
Answer: e. COC(=O)c1ccc(NCN2C(=O)C3C4CCC(C4)C3C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(NCN2C(=O)C3C4CCC(C4)C3C2=O)cc1
COC(=O)c1ccc(NCN2C(=O)C3C4CCC(C4)C3C2=O)cc1
methyl 4-[(3,5-dioxo-4-azatricyclo[5.2.1.02,6]decan-4-yl)methylamino]benzoate