Task: Answer the multiple-choice question.
Question: Which drug has a -2.890\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1ccc(S(=O)(=O)N2CCOC2CNC(=O)C(=O)NCc2ccncc2)cc1OC
b.) O=C(CNC(=O)N1CC(=O)Nc2ccccc21)Nc1nccs1
c.) CCOC(=O)C(=CNc1ccc(C(O)(C(=O)OCC)C(F)(F)F)cc1C)C(=O)OCC
d.) COc1ccc(NC(=O)NNC(=O)c2ccc3ccccc3c2O)cc1OC
e.) COc1ccc(/C=N/NC(=O)c2ccc3c(c2)OCCO3)c(OC)c1
Answer: c. CCOC(=O)C(=CNc1ccc(C(O)(C(=O)OCC)C(F)(F)F)cc1C)C(=O)OCC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C(=CNc1ccc(C(O)(C(=O)OCC)C(F)(F)F)cc1C)C(=O)OCC
CCOC(=O)C(=CNc1ccc(C(O)(C(=O)OCC)C(F)(F)F)cc1C)C(=O)OCC
diethyl 2-[[4-(3-ethoxy-1,1,1-trifluoro-2-hydroxy-3-oxopropan-2-yl)-2-methylanilino]methylidene]propanedioate