Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -0.522\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CCCCCCSc1ccc(-c2nc3ccc(C)cn3c2NC2CCCCC2)cc1.O=C(O)C(F)(F)F
b.) COc1ccc(NC(=O)CN(C)C(=O)c2cn(-c3ccccc3)nc2-c2ccc(Cl)cc2)cc1
c.) COC(=O)Cc1ccc(NC(=S)N2CCCCC2C)cc1
d.) Cc1ccc(Cn2ncc3c(N4CCN(C)CC4)ncnc32)cc1
e.) O=C1CC(C(=O)Nc2cccc(Cl)c2)n2ncnc2N1
Answer: d. Cc1ccc(Cn2ncc3c(N4CCN(C)CC4)ncnc32)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(Cn2ncc3c(N4CCN(C)CC4)ncnc32)cc1
Cc1ccc(Cn2ncc3c(N4CCN(C)CC4)ncnc32)cc1
1-[(4-methylphenyl)methyl]-4-(4-methylpiperazin-1-yl)pyrazolo[3,4-d]pyrimidine