Problem statement: Answer the multiple-choice question.
Question: Which compound has a -17.385\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1cc(OC)c(NS(=O)(=O)c2ccc3c(c2)NC(=O)CO3)cc1Cl
b.) O=C1CCCN1CN(C(=O)c1ccc2c(c1)OCO2)c1cccc(Cl)c1
c.) CCc1ccc(N(C(=O)c2csnn2)C(C(=O)NC(C)(C)C)c2ccccn2)cc1
d.) CC(=O)c1ccc(OCc2cc(C(=O)N3CCCCCCC3)no2)cc1
e.) O=C(NCCc1ccccc1)C(=O)N/N=C/c1ccccc1C(F)(F)F
Answer: c. CCc1ccc(N(C(=O)c2csnn2)C(C(=O)NC(C)(C)C)c2ccccn2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCc1ccc(N(C(=O)c2csnn2)C(C(=O)NC(C)(C)C)c2ccccn2)cc1
CCc1ccc(N(C(=O)c2csnn2)C(C(=O)NC(C)(C)C)c2ccccn2)cc1
N-[2-(tert-butylamino)-2-oxo-1-pyridin-2-ylethyl]-N-(4-ethylphenyl)thiadiazole-4-carboxamide