Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a 0.641\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COC(=O)C1=C(c2cccc(C#N)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCCCC1
[b] Cc1ccc(Cl)cc1NC(=O)CN1CCN(C(=O)C2CCCO2)CC1
[c] COc1cc(CNCCc2c[nH]c3ccccc23)cc(OC)c1.O=C(O)C(=O)O
[d] COc1ccc(CCN2CC(C(=O)N(C)Cc3cccnc3)CC2=O)cc1OC
[e] COc1ccc(CNC(=O)C(OC(=O)c2nsc(Cl)c2Cl)C(C)C)cc1
Answer: e. COc1ccc(CNC(=O)C(OC(=O)c2nsc(Cl)c2Cl)C(C)C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C(OC(=O)c2nsc(Cl)c2Cl)C(C)C)cc1
COc1ccc(CNC(=O)C(OC(=O)c2nsc(Cl)c2Cl)C(C)C)cc1
[1-[(4-methoxyphenyl)methylamino]-3-methyl-1-oxobutan-2-yl] 4,5-dichloro-1,2-thiazole-3-carboxylate