Problem statement: Answer the multiple choice question.
Question: Which compound has a 16.186\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CC(C)C(NC(=O)c1ccc(C(C)(C)C)cc1)C(=O)Nc1cccc(S(N)(=O)=O)c1
b: CCn1c(-c2ccccc2Cl)nn(CC(=O)Nc2cc(Cl)ccc2Cl)c1=S
c: NC(=O)[C@@H]1CCCNc2c(F)cc([N+](=O)[O-])cc2C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N1
d: COc1ccc(CC(=O)Nc2c3c(nn2-c2cccc(C)c2C)CS(=O)C3)cc1OC
e: S=C(NCCc1ccccc1)NCCN1CCOCC1
Answer: d. COc1ccc(CC(=O)Nc2c3c(nn2-c2cccc(C)c2C)CS(=O)C3)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CC(=O)Nc2c3c(nn2-c2cccc(C)c2C)CS(=O)C3)cc1OC
COc1ccc(CC(=O)Nc2c3c(nn2-c2cccc(C)c2C)CS(=O)C3)cc1OC
2-(3,4-dimethoxyphenyl)-N-[2-(2,3-dimethylphenyl)-5-oxo-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]acetamide