Task: Answer the multiple choice question.
Question: Which drug has a -4.408\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) CCCc1nnc(NC(=O)c2cn(CC)c3cc(N4CCN(C)CC4)c(F)cc3c2=O)s1
b.) COc1cc(C2C(C#N)=C(N)N(c3cccnc3)C3=C2C(=O)CCC3)ccc1O
c.) Cc1cccn2c(=O)c3cc(C(=O)NC4CCCC4)c(=N)n(CCc4ccccc4)c3nc12
d.) CCOC(=O)N1CCN(C(=O)CCS(=O)(=O)c2ccc3c(c2)CC(C)N3C(=O)CC)CC1
Answer: b. COc1cc(C2C(C#N)=C(N)N(c3cccnc3)C3=C2C(=O)CCC3)ccc1O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(C2C(C#N)=C(N)N(c3cccnc3)C3=C2C(=O)CCC3)ccc1O
COc1cc(C2C(C#N)=C(N)N(c3cccnc3)C3=C2C(=O)CCC3)ccc1O
2-amino-4-(4-hydroxy-3-methoxyphenyl)-5-oxo-1-pyridin-3-yl-4,6,7,8-tetrahydroquinoline-3-carbonitrile