Problem statement: Answer the multiple choice question.
Question: Which compound has a -7.818\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CCC(C)C(=O)Nc1nc2ccc(S(C)(=O)=O)cc2s1
b.) Cc1sc2nc3ccc(N4CCCCC4)nn3c(=O)c2c1C
c.) Cn1nc(-c2ccccc2)c(C(=O)Nc2ccc(Cl)cc2)c1Cl
d.) COc1cc(NC2c3ccccc3C(=O)N2c2cc(C)ccn2)cc(OC)c1OC
e.) Cc1ccc(S(=O)(=O)N2CCN(c3ncnc4ccccc34)CC2)cc1
Answer: e. Cc1ccc(S(=O)(=O)N2CCN(c3ncnc4ccccc34)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(S(=O)(=O)N2CCN(c3ncnc4ccccc34)CC2)cc1
Cc1ccc(S(=O)(=O)N2CCN(c3ncnc4ccccc34)CC2)cc1
4-[4-(4-methylphenyl)sulfonylpiperazin-1-yl]quinazoline