Task: Answer the multiple choice question.
Question: Which compound has a -0.442\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
(a) CNC(=S)N(Cc1cc2cc(C)ccc2n2nnnc12)CC(C)(C)CN(C)C
(b) COc1ccc(Cl)cc1NC(=O)CN(C)CC(=O)Nc1ccccc1N1CCOCC1.O=C(O)C(=O)O
(c) COC(=O)c1cnc(Oc2ccc(NC(=O)NC(=O)c3c(OC)cccc3OC)cc2)cc1C(F)(F)F
Answer: c. COC(=O)c1cnc(Oc2ccc(NC(=O)NC(=O)c3c(OC)cccc3OC)cc2)cc1C(F)(F)F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1cnc(Oc2ccc(NC(=O)NC(=O)c3c(OC)cccc3OC)cc2)cc1C(F)(F)F
COC(=O)c1cnc(Oc2ccc(NC(=O)NC(=O)c3c(OC)cccc3OC)cc2)cc1C(F)(F)F
methyl6-[4-[(2,6-dimethoxybenzoyl)carbamoylamino]phenoxy]-4-(trifluoromethyl)pyridine-3-carboxylate