Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -7.894\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1cc(/C=N/NC(=O)c2cccc(S(=O)(=O)N3CCCCC3)c2)cc(Br)c1O
b) C/C(=N\NC(=O)CN1CCN(Cc2ccccc2)CC1)c1cccs1
c) CC(C)=NOc1nc(NC(=O)NS(=O)(=O)c2ccccc2Cl)nc(N(C)C)n1
d) CC(C)C1Oc2ccccc2C(=O)N(CC(=O)c2ccc3c(c2)OCCO3)C1=O
e) O=C(CCNS(=O)(=O)c1ccccc1C(F)(F)F)N1CCN(c2ccccc2O)CC1
Answer: e. O=C(CCNS(=O)(=O)c1ccccc1C(F)(F)F)N1CCN(c2ccccc2O)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCNS(=O)(=O)c1ccccc1C(F)(F)F)N1CCN(c2ccccc2O)CC1
O=C(CCNS(=O)(=O)c1ccccc1C(F)(F)F)N1CCN(c2ccccc2O)CC1
N-[3-[4-(2-hydroxyphenyl)piperazin-1-yl]-3-oxopropyl]-2-(trifluoromethyl)benzenesulfonamide