Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 8.444\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) Cc1cc(C)c(-n2c(SCC(=O)N3CCOCC3)n[nH]c2=O)c(C)c1
b.) COc1ccc(S(=O)(=O)ON=C2CC(C)(C)N(C(C)=O)C(C)(C)C2)cc1
c.) OC(CNCCc1ccccc1)COc1ccc(OCC(O)CNCCc2ccccc2)cc1
d.) COc1ccccc1NS(=O)(=O)c1ccc(C(=O)NCC(c2ccccc2OC)N(C)C)cc1
e.) CC(C)C(NC(=O)/C(=C/c1ccco1)NC(=O)c1ccc(Br)o1)C(=O)O
Answer: d. COc1ccccc1NS(=O)(=O)c1ccc(C(=O)NCC(c2ccccc2OC)N(C)C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1NS(=O)(=O)c1ccc(C(=O)NCC(c2ccccc2OC)N(C)C)cc1
COc1ccccc1NS(=O)(=O)c1ccc(C(=O)NCC(c2ccccc2OC)N(C)C)cc1
N-[2-(dimethylamino)-2-(2-methoxyphenyl)ethyl]-4-[(2-methoxyphenyl)sulfamoyl]benzamide