Problem statement: Answer the multiple choice question.
Question: Which compound has a 3.544\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cn1cc(Cl)c(C(=O)Nc2nc3ccc(Cl)cc3s2)n1
b. Cc1cc(C)cc(-n2c(C)cc(/C=C3\C(=N)N4N=C(CC(C)C)SC4=NC3=O)c2C)c1
c. C=C(C)C1Cc2c(C)nn(-c3ccccn3)c2C1
d. Cc1cc(NC(=O)Nc2ccc(OCc3ccccc3)cc2)n(C)n1
e. CCOC(=O)c1c(NC(=O)Cn2cnc3sc(C)c(-c4ccccc4)c3c2=O)sc(C)c1C
Answer: e. CCOC(=O)c1c(NC(=O)Cn2cnc3sc(C)c(-c4ccccc4)c3c2=O)sc(C)c1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)c1c(NC(=O)Cn2cnc3sc(C)c(-c4ccccc4)c3c2=O)sc(C)c1C
CCOC(=O)c1c(NC(=O)Cn2cnc3sc(C)c(-c4ccccc4)c3c2=O)sc(C)c1C
ethyl 4,5-dimethyl-2-[[2-(6-methyl-4-oxo-5-phenylthieno[2,3-d]pyrimidin-3-yl)acetyl]amino]thiophene-3-carboxylate