Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -21.952\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Cc1ccc(Cl)cc1NS(=O)(=O)c1c(C)[nH]c(=O)[nH]c1=O
b Cc1ccc(Cl)cc1N1CCN(C(=S)NCc2ccco2)CC1
c Cc1ccc(-n2c(C)c([N+](=O)[O-])c3ccc(O)c(CN(C)C)c32)cc1
d COc1cc(-c2nc(CN(C)Cc3nnc(C)o3)c(C)o2)ccc1F
e O=C(CCN1C(=O)c2ccncc2C1=O)NCc1ccc(Cl)cc1
Answer: e. O=C(CCN1C(=O)c2ccncc2C1=O)NCc1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCN1C(=O)c2ccncc2C1=O)NCc1ccc(Cl)cc1
O=C(CCN1C(=O)c2ccncc2C1=O)NCc1ccc(Cl)cc1
N-[(4-chlorophenyl)methyl]-3-(1,3-dioxopyrrolo[3,4-c]pyridin-2-yl)propanamide