Problem statement: Answer the MCQ question.
Question: Which drug has a 5.812\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1cc(/C=C/c2cccc[n+]2C)ccc1OCC(=O)Nc1ccccc1C.[I-]
(b) CCn1nc(C(C)C)cc1C(=O)N1CCCC(CO)(Cc2ccc(F)cc2F)C1
(c) CCN(C(=O)CCS(=O)(=O)c1cccc2nonc12)c1ccc(F)cc1
(d) COc1ccc(C(CNC(=O)c2oc3ccc(OC)cc3c2C)N2CCCC2)cc1
(e) CN(C)/C=N/C(=S)Nc1ccc(Cl)cc1
Answer: b. CCn1nc(C(C)C)cc1C(=O)N1CCCC(CO)(Cc2ccc(F)cc2F)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCn1nc(C(C)C)cc1C(=O)N1CCCC(CO)(Cc2ccc(F)cc2F)C1
CCn1nc(C(C)C)cc1C(=O)N1CCCC(CO)(Cc2ccc(F)cc2F)C1
[3-[(2,4-difluorophenyl)methyl]-3-(hydroxymethyl)piperidin-1-yl]-(2-ethyl-5-propan-2-ylpyrazol-3-yl)methanone