Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -4.902\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) c1ccc(N2CCN(c3nnc(Cc4cccnc4)c4ccccc34)CC2)nc1
b.) C/C(=N\NC(=S)Nc1ccc(C(C)C)cc1)c1ccc2c(c1)OCO2
c.) COc1cc(-c2nc3ccc4ccccc4c3c3c2CCC3)cc(OC)c1OC
d.) O=C(CCN1C(=O)c2ccccc2C1=O)NC(=S)Nc1cccc(Cl)c1
e.) O=C(O)c1cccc(S(=O)(=O)Nc2ccc([N+](=O)[O-])cc2O)c1
Answer: a. c1ccc(N2CCN(c3nnc(Cc4cccnc4)c4ccccc34)CC2)nc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
c1ccc(N2CCN(c3nnc(Cc4cccnc4)c4ccccc34)CC2)nc1
c1ccc(N2CCN(c3nnc(Cc4cccnc4)c4ccccc34)CC2)nc1
1-(pyridin-3-ylmethyl)-4-(4-pyridin-2-ylpiperazin-1-yl)phthalazine