Problem statement: Answer the multiple-choice question.
Query: Which drug has a -11.968\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) O=C1Nc2cc(Cl)ccc2C1(N1CCNCC1)C(F)(F)F
(b) COC(=O)CCCC1=CC2=C(c3ccccc3)C(=O)C(C)(OC(=O)C3CCCC3)C(=O)C2=CN1c1ccccc1
(c) COc1cccc([C@@H]2CC=C(C(=O)O)[C@H](c3ccccc3F)N2S(=O)(=O)c2ccc(C)cc2)c1
(d) CCOC(=O)C1CSC(CC(=O)Nc2ccc(OC(F)(F)F)cc2)C(=O)N1
Answer: d. CCOC(=O)C1CSC(CC(=O)Nc2ccc(OC(F)(F)F)cc2)C(=O)N1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1CSC(CC(=O)Nc2ccc(OC(F)(F)F)cc2)C(=O)N1
CCOC(=O)C1CSC(CC(=O)Nc2ccc(OC(F)(F)F)cc2)C(=O)N1
ethyl 5-oxo-6-[2-oxo-2-[4-(trifluoromethoxy)anilino]ethyl]thiomorpholine-3-carboxylate