Problem statement: Answer the multiple-choice question.
Query: Which compound has a -8.646\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: COc1ccc(-c2ocnc2C(=O)Nc2ccccc2N2CCCCC2)cc1
b: COc1ccc(CCNC(=O)C2CCN(S(=O)(=O)N3CCC(C)CC3)CC2)cc1OC
c: Cc1ccc2[nH]c3c(c2c1)CN(C(=O)CN1c2ccc(F)cc2CCC1C)CC3
d: CC1(C)C(/C=C/C=C/C=C/C=C2\N(CCCCS(=O)(=O)[O-])c3ccc4ccccc4c3C2(C)C)=[N+](CCCCS(=O)(=O)[O-])c2ccc3ccccc3c21.[Na+]
e: O=C(CCc1nc(-c2ccccc2)c(-c2ccccc2)o1)OCc1ccc(Cl)cc1
Answer: a. COc1ccc(-c2ocnc2C(=O)Nc2ccccc2N2CCCCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2ocnc2C(=O)Nc2ccccc2N2CCCCC2)cc1
COc1ccc(-c2ocnc2C(=O)Nc2ccccc2N2CCCCC2)cc1
5-(4-methoxyphenyl)-N-(2-piperidin-1-ylphenyl)-1,3-oxazole-4-carboxamide