Problem statement: Answer the MCQ question.
Question: Which drug has a -10.552\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C(C1=C[C@@H](c2ccccc2)C[C@@H](OCCCCO)O1)N1CCN(Cc2ccc3c(c2)OCO3)CC1
b.) CC(OC(=O)c1ccc(NC(=O)CC#N)cc1)C(=O)NCCC1=CCCCC1
c.) CCC(=O)Nc1ccc(C=C(C(C)=O)C(C)=O)cc1
d.) CC1CCN(C(=O)COC(=O)c2cccc(S(=O)(=O)N(C)c3ccccc3)c2)CC1
e.) Cc1nnsc1C(=O)NNc1ccc(C(C)C)cc1
Answer: a. O=C(C1=C[C@@H](c2ccccc2)C[C@@H](OCCCCO)O1)N1CCN(Cc2ccc3c(c2)OCO3)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(C1=C[C@@H](c2ccccc2)C[C@@H](OCCCCO)O1)N1CCN(Cc2ccc3c(c2)OCO3)CC1
O=C(C1=C[C@@H](c2ccccc2)C[C@@H](OCCCCO)O1)N1CCN(Cc2ccc3c(c2)OCO3)CC1
[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]-[(2S,4S)-2-(4-hydroxybutoxy)-4-phenyl-3,4-dihydro-2H-pyran-6-yl]methanone