Problem statement: Answer the MCQ question.
Question: Which drug has a 12.976\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) O=C(NCc1cccc(Cl)c1)C1CCC(=O)N(C2CC2)C1
(b) COC(=O)[C@@]12CCCN1[C@H](c1ccc(SC3CCCCC3)cc1)[C@H]1C(=O)N(C)C(=O)[C@H]12.O=C(O)C(F)(F)F
(c) CN1CC(=O)NC1=NC(=O)c1cc(F)c(F)cc1Cl
(d) CCn1c(CNC(=O)c2cc(OC)c(OC)c(OC)c2)cc2cc(C)ccc21
(e) O=C(c1ccc(OC2CCN(CCCc3ccccc3)CC2)cc1)N1CCCC1
Answer: b. COC(=O)[C@@]12CCCN1[C@H](c1ccc(SC3CCCCC3)cc1)[C@H]1C(=O)N(C)C(=O)[C@H]12.O=C(O)C(F)(F)F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)[C@@]12CCCN1[C@H](c1ccc(SC3CCCCC3)cc1)[C@H]1C(=O)N(C)C(=O)[C@H]12.O=C(O)C(F)(F)F
COC(=O)[C@@]12CCCN1[C@H](c1ccc(SC3CCCCC3)cc1)[C@H]1C(=O)N(C)C(=O)[C@H]12.O=C(O)C(F)(F)F
methyl (3aS,4S,8aS,8bR)-4-(4-cyclohexylsulfanylphenyl)-2-methyl-1,3-dioxo-3a,4,6,7,8,8b-hexahydropyrrolo[3,4-a]pyrrolizine-8a-carboxylate;2,2,2-trifluoroacetic acid