Problem statement: Answer the multiple-choice question.
Query: Which compound has a 4.273\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) Cc1ccc(CSc2nnc(Cn3c(=O)sc4ccccc43)n2C)cc1
(b) O=C(Nc1ccccn1)C1CCCN(c2ncnc3c2nc2n3CCCCC2)C1
(c) COc1cc(C(=O)NCC(=O)OCn2nnc3ccccc3c2=O)cc(OC)c1OC
(d) O=C(O)CC1(CC(=O)Nc2ccc(Br)cc2)CCCCC1
(e) O=C(O)CNC(=O)/C(=C\c1cccc([N+](=O)[O-])c1)NC(=O)c1ccco1
Answer: b. O=C(Nc1ccccn1)C1CCCN(c2ncnc3c2nc2n3CCCCC2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1ccccn1)C1CCCN(c2ncnc3c2nc2n3CCCCC2)C1
O=C(Nc1ccccn1)C1CCCN(c2ncnc3c2nc2n3CCCCC2)C1
N-pyridin-2-yl-1-(7,8,9,10-tetrahydro-6H-purino[9,8-a]azepin-4-yl)piperidine-3-carboxamide