Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a -18.414\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) Cc1[nH]c(C)c(S(=O)(=O)NCCc2ccccc2)c1C(=O)N1CCCCC1
b.) O=C(Nc1ccsc1C(=O)O)c1cccc(C(F)(F)F)c1
c.) COc1ccc(NC(=O)c2nc[nH]c2C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cc1
d.) CC(C)(C)c1ccc(OCCC(=O)Nc2cccc(S(=O)(=O)N3CCCC3)c2)cc1
Answer: c. COc1ccc(NC(=O)c2nc[nH]c2C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)c2nc[nH]c2C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cc1
COc1ccc(NC(=O)c2nc[nH]c2C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cc1
tert-butyl 4-[4-[(4-methoxyphenyl)carbamoyl]-1H-imidazole-5-carbonyl]piperazine-1-carboxylate