Problem statement: Answer the multiple-choice question.
Query: Which drug has a 26.366\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CCN(Cc1ccccc1)S(=O)(=O)c1ccc(S(=O)(=O)N2CCN(CCC#N)CC2)cc1
[b] Cc1cc(NC(=O)C2C3C(=O)N(c4cccnc4)C(C(=O)NC(C)(C)C)C34C=CC2(C)O4)no1
[c] CCn1c(Cc2cccs2)nnc1SCC(=O)NC1CC1
[d] Cc1cccn2c(CN3CCCC(c4ccccc4)C3)c(C(=O)N3CCOCC3)nc12
[e] COc1cccc(N2CCN(C(=O)c3ccccc3SCC(=O)NCc3ccco3)CC2)c1
Answer: b. Cc1cc(NC(=O)C2C3C(=O)N(c4cccnc4)C(C(=O)NC(C)(C)C)C34C=CC2(C)O4)no1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cc(NC(=O)C2C3C(=O)N(c4cccnc4)C(C(=O)NC(C)(C)C)C34C=CC2(C)O4)no1
Cc1cc(NC(=O)C2C3C(=O)N(c4cccnc4)C(C(=O)NC(C)(C)C)C34C=CC2(C)O4)no1
2-N-tert-butyl-7-methyl-6-N-(5-methyl-1,2-oxazol-3-yl)-4-oxo-3-pyridin-3-yl-10-oxa-3-azatricyclo[5.2.1.01,5]dec-8-ene-2,6-dicarboxamide