Problem statement: Answer the multiple-choice question.
Question: Which compound has a 15.091\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CCOC(=O)c1sc(NC(=O)CS(=O)(=O)c2ccc(C)cc2)nc1C
b. Cc1ccc(S(=O)(=O)N(C)c2ccc(C(=O)Nc3ccccc3C(=O)N3CCOCC3)cc2)cc1
c. Cc1ccc(NC(=O)c2cncc(Br)c2)nc1
d. Cc1nc(NCCOc2ccccc2)sc1C(=O)Nc1ccccc1
e. CC(=O)Nc1ccc2c(CSc3nnc(N)s3)cc(=O)oc2c1
Answer: b. Cc1ccc(S(=O)(=O)N(C)c2ccc(C(=O)Nc3ccccc3C(=O)N3CCOCC3)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(S(=O)(=O)N(C)c2ccc(C(=O)Nc3ccccc3C(=O)N3CCOCC3)cc2)cc1
Cc1ccc(S(=O)(=O)N(C)c2ccc(C(=O)Nc3ccccc3C(=O)N3CCOCC3)cc2)cc1
4-[methyl-(4-methylphenyl)sulfonylamino]-N-[2-(morpholine-4-carbonyl)phenyl]benzamide