Task: Answer the multiple choice question.
Query: Which drug exhibits a -21.448\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
(a) CCOC(=O)C1CCCN(S(=O)(=O)c2c(C)noc2C)C1
(b) O=c1[nH]c(CN2CCN(S(=O)(=O)/C=C/c3ccccc3)CC2)nc2cc(Cl)ccc12
(c) CC/C(=N\N=C1\SC(C)C(=O)N1Cc1ccco1)c1ccccc1
Answer: b. O=c1[nH]c(CN2CCN(S(=O)(=O)/C=C/c3ccccc3)CC2)nc2cc(Cl)ccc12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=c1[nH]c(CN2CCN(S(=O)(=O)/C=C/c3ccccc3)CC2)nc2cc(Cl)ccc12
O=c1[nH]c(CN2CCN(S(=O)(=O)/C=C/c3ccccc3)CC2)nc2cc(Cl)ccc12
7-chloro-2-[[4-[(E)-2-phenylethenyl]sulfonylpiperazin-1-yl]methyl]-3H-quinazolin-4-one