Task: Answer the multiple-choice question.
Question: Which drug has a 13.460\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CCOC(=O)c1cc(CC)sc1NC(=O)CN1C(=O)C(=O)N(CC(C)C)C1=O
b. CNS(=O)(=O)c1cn(CC(=O)NCc2ccc(N(C)C)cc2)cc1S(=O)(=O)NC
c. COC(c1ccccc1)c1nnc(CCC(=O)N2CCN(CCOc3ccccc3)CC2)o1
d. O=C(CNC(=O)c1ccccc1)Nc1ccc(Br)cc1C(=O)c1ccccc1
e. Nc1ccccc1C(=O)NCC1(c2ccccc2)CCCC1
Answer: c. COC(c1ccccc1)c1nnc(CCC(=O)N2CCN(CCOc3ccccc3)CC2)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(c1ccccc1)c1nnc(CCC(=O)N2CCN(CCOc3ccccc3)CC2)o1
COC(c1ccccc1)c1nnc(CCC(=O)N2CCN(CCOc3ccccc3)CC2)o1
3-[5-[methoxy(phenyl)methyl]-1,3,4-oxadiazol-2-yl]-1-[4-(2-phenoxyethyl)piperazin-1-yl]propan-1-one