Problem statement: Answer the multiple-choice question.
Query: Which compound has a 18.089\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COC(=O)c1c(NC(=O)c2ccccc2F)sc2c1C(C(=O)OC)CC2
b. CC(C)NS(=O)(=O)c1ccc(OCC(=O)NC(C)c2ccccc2)cc1
c. CC(C)(C)NS(=O)(=O)c1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1
d. O=C1CN(C(=O)COc2ccc(Br)cc2Br)c2ccccc2N1
e. COc1cccc(CNC(=O)c2nnn(CC(=O)Nc3cc(C)ccc3C)c2N)c1
Answer: c. CC(C)(C)NS(=O)(=O)c1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)(C)NS(=O)(=O)c1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1
CC(C)(C)NS(=O)(=O)c1ccc(Oc2ncc(C(F)(F)F)cc2Cl)cc1
N-tert-butyl-4-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy]benzenesulfonamide