Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 9.677\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=c1cc(-c2ccc(O)cc2)oc2cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O[C@@H]3OC[C@](O)(CO)[C@H]3O)cc(O)c12
b. CCC1CCCCN1CCCNC(=O)c1cn(C)c2ccc(S(=O)(=O)N(C)C3CCCCC3)cc2c1=O
c. Cc1cc([N+](=O)[O-])nn1CC(=O)NCCCN1CCOCC1
d. Cc1ccc(S(=O)(=O)N(C)C)cc1NC(=S)N1CCCCC1CO
e. COCCN1C(=O)c2cc(C(=O)Nc3cccc(F)c3)ccc2C1Nc1cccc(F)c1
Answer: e. COCCN1C(=O)c2cc(C(=O)Nc3cccc(F)c3)ccc2C1Nc1cccc(F)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCCN1C(=O)c2cc(C(=O)Nc3cccc(F)c3)ccc2C1Nc1cccc(F)c1
COCCN1C(=O)c2cc(C(=O)Nc3cccc(F)c3)ccc2C1Nc1cccc(F)c1
1-(3-fluoroanilino)-N-(3-fluorophenyl)-2-(2-methoxyethyl)-3-oxo-1H-isoindole-5-carboxamide