Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 1.202\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CC1(NC(=O)c2cc(-c3cccs3)nn2-c2ccccc2)CCS(=O)(=O)C1
b) O=C(c1ccc(OC2CCN(C(=O)c3cccnc3)CC2)cc1)N1CCCCCC1
c) O=C(O)CCNc1ccc2c(c1)OCCO2
d) O=C(NCc1ccc(F)cc1)c1ccc(NC(=O)C2CCCO2)cc1
e) Cc1ccc([C@@H]2C3COCC=C3C(C#N)=C(N)C2(C#N)C#N)o1
Answer: e. Cc1ccc([C@@H]2C3COCC=C3C(C#N)=C(N)C2(C#N)C#N)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc([C@@H]2C3COCC=C3C(C#N)=C(N)C2(C#N)C#N)o1
Cc1ccc([C@@H]2C3COCC=C3C(C#N)=C(N)C2(C#N)C#N)o1
(8R)-6-amino-8-(5-methylfuran-2-yl)-1,3,8,8a-tetrahydroisochromene-5,7,7-tricarbonitrile