Task: Answer the multiple-choice question.
Question: Which drug has a 8.148\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccc(CN(C)CC2CCCN(CCc3ccccc3C)C2)cc1O
[b] NC(=O)[C@H]1CC2(CC(c3cccc(NC(=O)COc4ccc(Cl)cc4)c3)=NO2)CN1C(=O)CC(c1ccccc1)c1ccccc1
[c] COc1ccc(N2CC(NC(=O)NCCC(C)C)CC2=O)cc1
[d] O=C(C[n+]1ccc2ccccc2c1)c1ccccc1.[Br-]
[e] COc1ccc(CCNC(=O)CSc2n[nH]c(N)n2)cc1
Answer: b. NC(=O)[C@H]1CC2(CC(c3cccc(NC(=O)COc4ccc(Cl)cc4)c3)=NO2)CN1C(=O)CC(c1ccccc1)c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
NC(=O)[C@H]1CC2(CC(c3cccc(NC(=O)COc4ccc(Cl)cc4)c3)=NO2)CN1C(=O)CC(c1ccccc1)c1ccccc1
NC(=O)[C@H]1CC2(CC(c3cccc(NC(=O)COc4ccc(Cl)cc4)c3)=NO2)CN1C(=O)CC(c1ccccc1)c1ccccc1
(8R)-3-[3-[[2-(4-chlorophenoxy)acetyl]amino]phenyl]-7-(3,3-diphenylpropanoyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide