Task: Answer the multiple choice question.
Question: Which compound has a -47.273\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1cc(Cl)c([C@@H]2C[C@H]3CN(c4ccccc4)C(=O)[C@]34CCCN24)cc1OC
[b] COC(=O)C1=C(C)N(CCc2cc(OC)c(OC)c(OC)c2)C(=O)N[C@H]1c1ccccc1
[c] C[n+]1cccc(C(=O)Nc2ccccc2)c1.[Cl-]
[d] Cc1noc(C)c1C(=O)OCC(=O)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1
[e] Cc1ccc(S(=O)(=O)N(CC(=O)Nc2ccc(C(N)=O)cc2)C(=O)N2CCN(C)CC2)cc1
Answer: a. COc1cc(Cl)c([C@@H]2C[C@H]3CN(c4ccccc4)C(=O)[C@]34CCCN24)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(Cl)c([C@@H]2C[C@H]3CN(c4ccccc4)C(=O)[C@]34CCCN24)cc1OC
COc1cc(Cl)c([C@@H]2C[C@H]3CN(c4ccccc4)C(=O)[C@]34CCCN24)cc1OC
(1S,5S,7S)-7-(2-chloro-4,5-dimethoxyphenyl)-3-phenyl-3,8-diazatricyclo[6.3.0.01,5]undecan-2-one