Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 13.037\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CCCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(C)cc2)c(N2CCC(C(N)=O)CC2)s1
b. Cn1cc(Br)c(-c2cccc(NC(=O)CCC(=O)O)c2)n1
c. Cc1cccc(NC(=O)COC(=O)c2cc(C)n(C3CC3)c2C)c1
d. CC(C)(C)n1nnnc1C(c1cccnc1)N1CCN(c2ccccn2)CC1
e. COCCNC(=O)CC(=O)N/N=C/c1ccc(C(=O)OC)cc1
Answer: d. CC(C)(C)n1nnnc1C(c1cccnc1)N1CCN(c2ccccn2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)(C)n1nnnc1C(c1cccnc1)N1CCN(c2ccccn2)CC1
CC(C)(C)n1nnnc1C(c1cccnc1)N1CCN(c2ccccn2)CC1
1-[(1-tert-butyltetrazol-5-yl)-pyridin-3-ylmethyl]-4-pyridin-2-ylpiperazine