Task: Answer the multiple-choice question.
Question: Which compound has a -1.726\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1ccc(-c2nc(-c3ccc4c(c3)NC(=O)CO4)cs2)cc1
[b] N#CCSc1nc2ccccc2c(=O)n1CC1CCCC1
[c] COc1ccc(CCn2c(SCCN3CCCCC3)nc3ccccc3c2=O)cc1OC
[d] CC(=O)Nc1ccc(NC(=O)COc2cc(O)c3c(c2)OC(C)(C)CC3=O)cc1
[e] C/C(=C\C(=O)c1ccc(Br)cc1)NNC(=O)c1ccc(O)cc1
Answer: a. COc1ccc(-c2nc(-c3ccc4c(c3)NC(=O)CO4)cs2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2nc(-c3ccc4c(c3)NC(=O)CO4)cs2)cc1
COc1ccc(-c2nc(-c3ccc4c(c3)NC(=O)CO4)cs2)cc1
6-[2-(4-methoxyphenyl)-1,3-thiazol-4-yl]-4H-1,4-benzoxazin-3-one