Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a -6.555\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1ccc(CNC(=O)c2ccc3c(c2)NC(=O)C(C)S3)cc1
b O=C(CSCc1ccccc1)Nc1ccc2c(c1)OCO2
c CCOC(=O)c1c(CCl)nc2ccccc2c1C.Cl
d O=C1N(c2ccccc2C(F)(F)F)O[C@]1(c1ccccc1)C1CCCCC1
e N#Cc1ccsc1NC(=O)CSc1nnnn1-c1ccc(O)cc1
Answer: d. O=C1N(c2ccccc2C(F)(F)F)O[C@]1(c1ccccc1)C1CCCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1N(c2ccccc2C(F)(F)F)O[C@]1(c1ccccc1)C1CCCCC1
O=C1N(c2ccccc2C(F)(F)F)O[C@]1(c1ccccc1)C1CCCCC1
(4S)-4-cyclohexyl-4-phenyl-2-[2-(trifluoromethyl)phenyl]oxazetidin-3-one