Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -16.598\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CC1CCN(C(=O)CCc2ccc(S(=O)(=O)NC(C)C)cc2)CC1
(b) CC(C)c1cc(CNC(=O)C2CCC(=O)N(CCc3ccc(Cl)cc3)C2)on1
(c) Cc1ccc(C2CC2C(=O)NN)cc1
(d) Cc1ccc(C(=O)NCC2CCCO2)cc1S(=O)(=O)N1CCCCC1
(e) CCc1nc(SCC(=O)Nc2cc(C)on2)c2c(C)c(C)sc2n1
Answer: b. CC(C)c1cc(CNC(=O)C2CCC(=O)N(CCc3ccc(Cl)cc3)C2)on1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)c1cc(CNC(=O)C2CCC(=O)N(CCc3ccc(Cl)cc3)C2)on1
CC(C)c1cc(CNC(=O)C2CCC(=O)N(CCc3ccc(Cl)cc3)C2)on1
1-[2-(4-chlorophenyl)ethyl]-2-oxo-N-[(3-propan-2-yl-1,2-oxazol-5-yl)methyl]piperidine-5-carboxamide