Problem statement: Answer the multiple choice question.
Question: Which compound has a 4.388\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1ccc(SCC(=O)Nc2ccc(C(=O)Nc3ccc(O)cc3)cc2)cc1
b) CN(CCOc1ccc(Cl)cc1)C(=O)c1ccc(S(=O)(=O)N2CCOCC2)cc1
c) CCN(Cc1ccc(NC(C)=O)cc1)CC1CCCN(CCc2cccc(F)c2)C1
d) COc1ccc(CCN2CC(C(=O)NCCc3ccc(F)cc3)CCC2=O)cc1
e) CSc1ccccc1NC(=O)COC(=O)c1c[nH]c(=O)[nH]c1=O
Answer: d. COc1ccc(CCN2CC(C(=O)NCCc3ccc(F)cc3)CCC2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CCN2CC(C(=O)NCCc3ccc(F)cc3)CCC2=O)cc1
COc1ccc(CCN2CC(C(=O)NCCc3ccc(F)cc3)CCC2=O)cc1
N-[2-(4-fluorophenyl)ethyl]-1-[2-(4-methoxyphenyl)ethyl]-6-oxopiperidine-3-carboxamide