Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 1.958\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccc(CNC(=O)CSc2ccsc2[N+](=O)[O-])cc1
b) CCOC(=O)C1(Cc2ccccc2C(F)(F)F)CCN(C(=O)c2cc(C)n(C)n2)CC1
c) Cc1cc(OC(C)C(=O)N[C@H](C(=O)O)c2ccccc2)c2c3c(c(=O)oc2c1)CCC3
d) NC(=O)c1ccccc1OCCOc1ccc(Br)cc1
e) COc1cc(OC)cc(-c2cn[nH]c2N)c1
Answer: b. CCOC(=O)C1(Cc2ccccc2C(F)(F)F)CCN(C(=O)c2cc(C)n(C)n2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1(Cc2ccccc2C(F)(F)F)CCN(C(=O)c2cc(C)n(C)n2)CC1
CCOC(=O)C1(Cc2ccccc2C(F)(F)F)CCN(C(=O)c2cc(C)n(C)n2)CC1
ethyl 1-(1,5-dimethylpyrazole-3-carbonyl)-4-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxylate