Problem statement: Answer the MCQ question.
Question: Which compound has a -0.449\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CC(=O)Nc1ccccc1NC(=O)c1ccccc1-c1ccccc1
b. COc1ccc(NC(=O)c2c(C)nn(-c3ccccc3)c2Cl)cc1
c. CC(C)(C)C1CCC2(CC1)C(C#N)=C(SCC(=O)Nc1ccccc1)NC(=O)C2C#N
d. O=C(COC(=O)CNC(=O)c1ccccc1F)NCCNC(=O)COC(=O)CNC(=O)c1ccccc1F
e. Cc1cc(C)c(NC(=O)CN2C(=O)NC3(CCOc4ccccc43)C2=O)c(C)c1
Answer: e. Cc1cc(C)c(NC(=O)CN2C(=O)NC3(CCOc4ccccc43)C2=O)c(C)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cc(C)c(NC(=O)CN2C(=O)NC3(CCOc4ccccc43)C2=O)c(C)c1
Cc1cc(C)c(NC(=O)CN2C(=O)NC3(CCOc4ccccc43)C2=O)c(C)c1
2-(2',5'-dioxospiro[2,3-dihydrochromene-4,4'-imidazolidine]-1'-yl)-N-(2,4,6-trimethylphenyl)acetamide