Problem statement: Answer the multiple-choice question.
Query: Which drug has a -0.461\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1cccc(NC(=O)C(=O)NCCCc2ccccc2)c1
b. COc1ccc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc1OC
c. COc1ccc(N2C(=O)CC(N3CCN(c4ccc(C(=O)c5cccnc5)cc4)CC3)C2=O)cc1
d. CN1CCN(C(=O)CCc2ncc(C(F)(F)F)cc2Cl)CC1
e. CC(OC(=O)CCc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccc(C(C)(C)C)cc1
Answer: b. COc1ccc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc1OC
COc1ccc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc1OC
5-(1,3-benzodioxol-5-yl)-N-(3,4-dimethoxyphenyl)-1,2-oxazole-3-carboxamide