Problem statement: Answer the multiple choice question.
Query: Which drug has a -2.003\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a O=C(O)C1Nc2c(Cl)cc(Cl)cc2C2C=CCC12
b COCCNC(=O)NC(=O)COC(=O)c1ccc2[nH]c3c(c2c1)CCCC3
c CN(C(=O)COc1coc(CN2CCN(c3ccccc3)CC2)cc1=O)c1ccccc1
d O=C(COC(=O)CCSc1ccccc1)Nc1cc(F)ccc1F
e Cc1cc(C)cc(-n2c(SCC(=O)NCc3ccc4c(c3)OCO4)nc3ccccc3c2=O)c1
Answer: c. CN(C(=O)COc1coc(CN2CCN(c3ccccc3)CC2)cc1=O)c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(C(=O)COc1coc(CN2CCN(c3ccccc3)CC2)cc1=O)c1ccccc1
CN(C(=O)COc1coc(CN2CCN(c3ccccc3)CC2)cc1=O)c1ccccc1
N-methyl-2-[4-oxo-6-[(4-phenylpiperazin-1-yl)methyl]pyran-3-yl]oxy-N-phenylacetamide