Problem statement: Answer the multiple-choice question.
Query: Which compound has a 0.408\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a. N#Cc1ccccc1Sc1ccccc1C(=O)Nc1ccc2ccccc2c1
b. COc1ccccc1NC(=O)C1CCCCN1S(=O)(=O)c1ccc(F)cc1
c. O=C(CNC(=O)c1ccccc1F)NCCc1ccc(Cl)cc1Cl
Answer: b. COc1ccccc1NC(=O)C1CCCCN1S(=O)(=O)c1ccc(F)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1NC(=O)C1CCCCN1S(=O)(=O)c1ccc(F)cc1
COc1ccccc1NC(=O)C1CCCCN1S(=O)(=O)c1ccc(F)cc1
1-(4-fluorophenyl)sulfonyl-N-(2-methoxyphenyl)piperidine-2-carboxamide