Problem statement: Answer the multiple choice question.
Query: Which compound has a -12.264\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCC(NC(=O)c1cc(COc2cncc(Cl)c2)on1)c1ccncc1
b. COC(=O)c1c(NC(=O)CSc2nc3ccccc3c(=O)n2-c2ccccc2)sc(C)c1C
c. O=C(N/N=C/c1ccc([N+](=O)[O-])o1)c1cc(-c2ccc(-c3ccccc3)cc2)nc2ccccc12
d. COc1ccccc1N(CN1CCCC1=O)C(=O)c1ccccc1F
e. N#CCCN(C(=O)COC(=O)CCc1c[nH]c2ccccc12)c1ccc(F)cc1
Answer: d. COc1ccccc1N(CN1CCCC1=O)C(=O)c1ccccc1F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1N(CN1CCCC1=O)C(=O)c1ccccc1F
COc1ccccc1N(CN1CCCC1=O)C(=O)c1ccccc1F
2-fluoro-N-(2-methoxyphenyl)-N-[(2-oxopyrrolidin-1-yl)methyl]benzamide