Problem statement: Answer the multiple choice question.
Query: Which drug has a 21.465\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(C2/C(=C(/O)c3ccc4c(c3)CC(C)O4)C(=O)C(=O)N2CCCN2CCOCC2)cc1OC
b. O=C(NC1CCCCC1)c1ccc(CS(=O)(=O)Cc2ccccc2F)o1
c. O=C(NC1CCCC1)c1cccc(Cl)c1
d. COc1ccc(-n2nc(C(=O)NCC(=O)N3CCN(C)CC3)c3ccccc3c2=O)cc1
e. N#CC/C(N)=N/NC(=O)CCCNc1ncc(C(F)(F)F)cc1Cl
Answer: e. N#CC/C(N)=N/NC(=O)CCCNc1ncc(C(F)(F)F)cc1Cl
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N#CC/C(N)=N/NC(=O)CCCNc1ncc(C(F)(F)F)cc1Cl
N#CC/C(N)=N/NC(=O)CCCNc1ncc(C(F)(F)F)cc1Cl
N-[(Z)-(1-amino-2-cyanoethylidene)amino]-4-[[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino]butanamide