Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 22.425\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a) c1ccc(OCCOc2ncnc3sccc23)cc1
b) O=CN1CCCN(Cc2nc(Cc3ccccc3F)no2)CC1
c) COC(=O)C1=C(C)Nc2c(c(=O)n(C)c(=O)n2C)C1c1ccncc1
Answer: c. COC(=O)C1=C(C)Nc2c(c(=O)n(C)c(=O)n2C)C1c1ccncc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(C)Nc2c(c(=O)n(C)c(=O)n2C)C1c1ccncc1
COC(=O)C1=C(C)Nc2c(c(=O)n(C)c(=O)n2C)C1c1ccncc1
methyl 1,3,7-trimethyl-2,4-dioxo-5-pyridin-4-yl-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylate