Problem statement: Answer the MCQ question.
Query: Which drug has a -9.013\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1cc2[nH]c(=O)c(=O)[nH]c2cc1S(=O)(=O)NCc1ccccc1
b. CCOC(=O)CC1COc2ccccc2N1C(=O)c1ccc(F)cc1
c. CC(C)c1cc(C(=O)N2CCCC(CCC(=O)N3CCN(c4ccccn4)CC3)C2)no1
d. C/C(=N/NC(=O)CN1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1)c1ccncc1
e. O=C(COC(=O)C1C2CC3OC(=O)C1C3C2)Nc1ccc(Cl)cc1
Answer: e. O=C(COC(=O)C1C2CC3OC(=O)C1C3C2)Nc1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COC(=O)C1C2CC3OC(=O)C1C3C2)Nc1ccc(Cl)cc1
O=C(COC(=O)C1C2CC3OC(=O)C1C3C2)Nc1ccc(Cl)cc1
[2-(4-chloroanilino)-2-oxoethyl]5-oxo-4-oxatricyclo[4.2.1.03,7]nonane-9-carboxylate