Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 10.883\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CC1(C)Oc2ccc3ccc(=O)oc3c2/C(=C/N)C1=O
(b) CCn1c(=NC(=O)COc2ccccc2)sc2cccc(F)c21
(c) COc1ccc(CC(NC(C)=O)C(=O)NC2CCN(c3c(Cc4ccccc4)c(C)nc4ncnn34)CC2)c(OC)c1
(d) CCN(CC)CCNC(C(=O)Nc1cccc(C(C)=O)c1)c1ccccc1.O=C(O)C(=O)O
(e) O=C(N/N=C\c1ccc[nH]1)c1cncc(Br)c1
Answer: c. COc1ccc(CC(NC(C)=O)C(=O)NC2CCN(c3c(Cc4ccccc4)c(C)nc4ncnn34)CC2)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CC(NC(C)=O)C(=O)NC2CCN(c3c(Cc4ccccc4)c(C)nc4ncnn34)CC2)c(OC)c1
COc1ccc(CC(NC(C)=O)C(=O)NC2CCN(c3c(Cc4ccccc4)c(C)nc4ncnn34)CC2)c(OC)c1
2-acetamido-N-[1-(6-benzyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)piperidin-4-yl]-3-(2,4-dimethoxyphenyl)propanamide