Problem statement: Answer the MCQ question.
Question: Which drug has a 3.112\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1ccccc1CN1C[C@@H]2C[C@@H](c3[nH]c4c(C)cccc4c3C)N3CCC[C@@]23C1=O
b CCOC(=O)c1c(NC(=O)CSc2nc3ccccc3c(=O)n2-c2ccccc2)sc(C(C)=O)c1C
c COc1ccc(C(=O)Cn2cc([N+](=O)[O-])nc2C)cc1
d Cn1cnc2cc(NC(=O)c3cccs3)ccc21
e Cc1cc(C)cc(OCCNC(=O)c2cc(S(=O)(=O)N3CCOCC3)ccc2F)c1
Answer: a. COc1ccccc1CN1C[C@@H]2C[C@@H](c3[nH]c4c(C)cccc4c3C)N3CCC[C@@]23C1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1CN1C[C@@H]2C[C@@H](c3[nH]c4c(C)cccc4c3C)N3CCC[C@@]23C1=O
COc1ccccc1CN1C[C@@H]2C[C@@H](c3[nH]c4c(C)cccc4c3C)N3CCC[C@@]23C1=O
(1S,5S,7S)-7-(3,7-dimethyl-1H-indol-2-yl)-3-[(2-methoxyphenyl)methyl]-3,8-diazatricyclo[6.3.0.01,5]undecan-2-one