Problem statement: Answer the MCQ question.
Question: Which compound has a 6.326\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CN1C(=O)C(C)(C)c2cc(S(=O)(=O)NCc3ccc(Cl)cc3)ccc21
(b) Cc1nc(CN2CCN(C(=O)NC3(c4ccccc4)CC3)CC2)cs1
(c) Cc1cc(-c2cccc(Br)c2)c(C#N)c(N)n1
(d) C/C(=N/N1CCN(Cc2ccccc2)CC1)c1ccc(Br)cc1
(e) CC(C)(C)[C@@H]1C=C(C(N)=O)O[C@H](OCc2ccc(CO)cc2)C1
Answer: e. CC(C)(C)[C@@H]1C=C(C(N)=O)O[C@H](OCc2ccc(CO)cc2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)(C)[C@@H]1C=C(C(N)=O)O[C@H](OCc2ccc(CO)cc2)C1
CC(C)(C)[C@@H]1C=C(C(N)=O)O[C@H](OCc2ccc(CO)cc2)C1
(2S,4S)-4-tert-butyl-2-[[4-(hydroxymethyl)phenyl]methoxy]-3,4-dihydro-2H-pyran-6-carboxamide