Problem statement: Answer the multiple-choice question.
Query: Which drug has a -52.961\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CNC(=O)N(C)c1ccc(C(O)(C(=O)OC)C(F)(F)F)cc1
b: Cc1cccc(Nc2nnc(SCC(=O)NC3CCCc4ccccc43)s2)c1
c: CCOC(=O)c1[nH]cnc1C(=O)Nc1ccc([N+](=O)[O-])cc1
d: COc1ccc(CN2CCC(CO)(Cc3ccccc3C(F)(F)F)CC2)c(F)c1
e: Cc1ccc2cccc(OCC(=O)N3CC(C)CC(C)C3)c2n1
Answer: d. COc1ccc(CN2CCC(CO)(Cc3ccccc3C(F)(F)F)CC2)c(F)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CN2CCC(CO)(Cc3ccccc3C(F)(F)F)CC2)c(F)c1
COc1ccc(CN2CCC(CO)(Cc3ccccc3C(F)(F)F)CC2)c(F)c1
[1-[(2-fluoro-4-methoxyphenyl)methyl]-4-[[2-(trifluoromethyl)phenyl]methyl]piperidin-4-yl]methanol