Task: Answer the multiple choice question.
Question: Which drug has a 16.014\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a.) COc1ccc(C2CC(c3ccccc3)=NN2C(=O)COC(=O)c2cccnc2)cc1
b.) COc1ccc([C@@]2(C(C)C)ON(c3ccccc3C(F)(F)F)C2=O)cc1
c.) CCOC(=O)C1(Cc2ccc(OC)cc2)CCN(C(=O)CC2CCC(=O)N2)CC1
d.) Cc1ccc(CN2CCCN(Cc3cc(C)ccc3C)S2(=O)=O)cc1
Answer: b. COc1ccc([C@@]2(C(C)C)ON(c3ccccc3C(F)(F)F)C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc([C@@]2(C(C)C)ON(c3ccccc3C(F)(F)F)C2=O)cc1
COc1ccc([C@@]2(C(C)C)ON(c3ccccc3C(F)(F)F)C2=O)cc1
(4R)-4-(4-methoxyphenyl)-4-propan-2-yl-2-[2-(trifluoromethyl)phenyl]oxazetidin-3-one