Problem statement: Answer the MCQ question.
Question: Which compound has a 1.725\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a. CCOc1ccccc1N1CCN(C/C(O)=C(\C#N)c2nc(-c3ccc(Cl)cc3)cs2)CC1
b. COc1cccc(NC(=O)CS(=O)(=O)Cc2nc(-c3ccc(C)cc3)oc2C)c1
c. COC(=O)CSc1nnc(CNc2ccc(F)cc2)o1
d. COc1c(C)cc(C(=O)C2CCCN(Cc3c(C)n(C)n(-c4ccccc4)c3=O)C2)cc1C
Answer: d. COc1c(C)cc(C(=O)C2CCCN(Cc3c(C)n(C)n(-c4ccccc4)c3=O)C2)cc1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1c(C)cc(C(=O)C2CCCN(Cc3c(C)n(C)n(-c4ccccc4)c3=O)C2)cc1C
COc1c(C)cc(C(=O)C2CCCN(Cc3c(C)n(C)n(-c4ccccc4)c3=O)C2)cc1C
4-[[3-(4-methoxy-3,5-dimethylbenzoyl)piperidin-1-yl]methyl]-1,5-dimethyl-2-phenylpyrazol-3-one