Problem statement: Answer the multiple-choice question.
Question: Which drug has a 8.435\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C(CN(C1CCCCC1)S(=O)(=O)c1ccc(F)cc1)NCCCO
b) Cl.O=C1CN=C(Nc2cccc(C(F)(F)F)c2)N1C1CCCC1
c) O=C(Nc1ccc(C(=O)NCCCN2CCCCC2)cc1)C1=CSCCO1
d) COc1ccc(Cl)cc1NC(=O)NCc1ccc2c(c1)OCO2
e) Cc1ccc(NC(=S)N(CCN(C)C)Cc2cccs2)c(C)c1
Answer: b. Cl.O=C1CN=C(Nc2cccc(C(F)(F)F)c2)N1C1CCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cl.O=C1CN=C(Nc2cccc(C(F)(F)F)c2)N1C1CCCC1
Cl.O=C1CN=C(Nc2cccc(C(F)(F)F)c2)N1C1CCCC1
1-cyclopentyl-2-[3-(trifluoromethyl)anilino]-4H-imidazol-5-one;hydrochloride