Problem statement: Answer the MCQ question.
Query: Which drug has a 10.661\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) N#Cc1c(/N=C/N2CCCC2)oc(-c2ccccc2)c1-c1ccccc1
(b) CCOC(=O)n1c(=O)[nH]c2ccc(Br)cc21
(c) CCOC(=O)C1CCCN(Cc2nc(C3CC3)no2)C1
(d) COc1ccc(CNC(=O)COC(=O)/C=C/c2ccc(Cl)cc2)cc1
(e) CCC(=O)Nc1cc(Cl)ccc1N1CCN(C(=O)CC)CC1
Answer: d. COc1ccc(CNC(=O)COC(=O)/C=C/c2ccc(Cl)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)COC(=O)/C=C/c2ccc(Cl)cc2)cc1
COc1ccc(CNC(=O)COC(=O)/C=C/c2ccc(Cl)cc2)cc1
[2-[(4-methoxyphenyl)methylamino]-2-oxoethyl] (E)-3-(4-chlorophenyl)prop-2-enoate