Problem statement: Answer the multiple choice question.
Question: Which drug has a -8.515\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) O=C(N/N=C/c1ccc(Br)o1)/C(=C/c1ccc([N+](=O)[O-])cc1)NC(=O)c1ccccc1
(b) CC1(C)CC(=NOC(=O)c2ccccc2)CC(C)(C)N1O
(c) COc1nc(N(C)C)nc(-n2nnc(C(C)=O)c2C)n1
(d) CC(C)(C)OC(=O)CC[C@@H](C(=O)NCCCCCCCCCCC(=O)N1CCN(C(=O)OC(C)(C)C)CC1)n1cc(CCCCCNC(=O)OC(C)(C)C)nn1
(e) COc1ccccc1C(CNC(=O)CN(C)S(=O)(=O)c1ccc(C)cc1)N1CCCC1
Answer: e. COc1ccccc1C(CNC(=O)CN(C)S(=O)(=O)c1ccc(C)cc1)N1CCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1C(CNC(=O)CN(C)S(=O)(=O)c1ccc(C)cc1)N1CCCC1
COc1ccccc1C(CNC(=O)CN(C)S(=O)(=O)c1ccc(C)cc1)N1CCCC1
N-[2-(2-methoxyphenyl)-2-pyrrolidin-1-ylethyl]-2-[methyl-(4-methylphenyl)sulfonylamino]acetamide