Task: Answer the multiple-choice question.
Query: Which compound has a 10.614\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CC(C)C(CCNC(=O)CC(Cc1ccccc1)c1ccco1)c1ccco1
b COc1ccc(C(=O)O/N=C2\CCS(=O)(=O)c3sccc32)cc1
c COc1cc(C2c3sc(=O)[nH]c3SC3C4CCC(C4)C23)ccc1O
d COc1ccc(CC(=O)NC(C)(C)C)cc1S(=O)(=O)N1CCOCC1
e COC(=O)C1=C(c2ccc(Cl)c(C(F)(F)F)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCO
Answer: e. COC(=O)C1=C(c2ccc(Cl)c(C(F)(F)F)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCO
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccc(Cl)c(C(F)(F)F)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCO
COC(=O)C1=C(c2ccc(Cl)c(C(F)(F)F)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCO
methyl (1R,5S)-3-[4-chloro-3-(trifluoromethyl)phenyl]-8-(2-hydroxyethylcarbamoyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate