Task: Answer the multiple-choice question.
Query: What is the human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM of a compound with the SMILES COc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)c(OC)c1?
Constraint: You must return none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) 6.324
(b) 18.685
(c) 8.375
(d) 12.845
(e) 6.038
Answer: b. 18.685\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
COc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)c(OC)c1
COc1ccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)c(OC)c1
1-amino-N-(2,4-dimethoxyphenyl)-5-morpholin-4-yl-6,7,8,9-tetrahydrothieno[2,3-c]isoquinoline-2-carboxamide