Task: Answer the MCQ question.
Query: Which drug has a -14.402\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: O=C(Cn1cc2c(n1)CCCCC2)NCc1ccccc1
b: O=C(Nc1c2c(nn1-c1ccccc1)CS(=O)(=O)C2)c1cc2ccccc2o1
c: COc1ccc(CCCc2n[nH]c(=S)o2)cc1C
d: O=C(CCn1nc(-c2ccccc2)ccc1=O)N1CCN(c2ccccn2)CC1
e: CN(CCc1ccccc1)C1CCCN(C(=O)Cn2cccn2)C1
Answer: d. O=C(CCn1nc(-c2ccccc2)ccc1=O)N1CCN(c2ccccn2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCn1nc(-c2ccccc2)ccc1=O)N1CCN(c2ccccn2)CC1
O=C(CCn1nc(-c2ccccc2)ccc1=O)N1CCN(c2ccccn2)CC1
2-[3-oxo-3-(4-pyridin-2-ylpiperazin-1-yl)propyl]-6-phenylpyridazin-3-one