Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a 0.615\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Cc1ccc(C(=O)NCC(=O)OCC(=O)Nc2ccccc2[N+](=O)[O-])cc1
b COC(=O)c1sc2ccccc2c1NC(=O)c1ccc(S(=O)(=O)N2CC(C)CC(C)C2)cc1
c C/C(=N/NC(=O)c1ccc(Br)o1)c1ccncc1
d Cc1noc(C)c1COc1ccc(C(=O)N2CCN(c3ccccc3F)CC2)cc1
e COc1c(C)cc(Br)cc1C(=O)Nc1cccc(-c2nc3ncccc3o2)c1
Answer: b. COC(=O)c1sc2ccccc2c1NC(=O)c1ccc(S(=O)(=O)N2CC(C)CC(C)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1sc2ccccc2c1NC(=O)c1ccc(S(=O)(=O)N2CC(C)CC(C)C2)cc1
COC(=O)c1sc2ccccc2c1NC(=O)c1ccc(S(=O)(=O)N2CC(C)CC(C)C2)cc1
methyl 3-[[4-(3,5-dimethylpiperidin-1-yl)sulfonylbenzoyl]amino]-1-benzothiophene-2-carboxylate