Problem statement: Answer the multiple choice question.
Question: Which compound has a 16.633\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. Cc1ccc(-n2nnnc2-c2cnn(-c3cccc(F)c3)c2C(F)(F)F)cc1
b. Cc1nc(S/C(=C/c2ccc(-c3cccc(Cl)c3)o2)C(=O)O)n[nH]1
c. Cc1ccc(C(=O)N(Cc2cccs2)C2CCS(=O)(=O)C2)cc1
d. CCc1cc(=O)[nH]c(SCC(=O)Nc2cc(C)on2)n1
e. Nc1sc(-c2ccccc2)cc1-c1n[nH]c(=S)n1C1CCCCC1
Answer: c. Cc1ccc(C(=O)N(Cc2cccs2)C2CCS(=O)(=O)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(C(=O)N(Cc2cccs2)C2CCS(=O)(=O)C2)cc1
Cc1ccc(C(=O)N(Cc2cccs2)C2CCS(=O)(=O)C2)cc1
N-(1,1-dioxothiolan-3-yl)-4-methyl-N-(thiophen-2-ylmethyl)benzamide