Problem statement: Answer the MCQ question.
Query: Which compound has a -18.203\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=c1c(Cc2ccccc2)c(O)ccn1CCc1cnc[nH]1
b) Cc1ccc(SCC(=O)NC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)cc1C
c) N#Cc1ccc(C(=O)Nc2cc(-c3ccccc3)nn2-c2ccccc2)cc1
d) CN(CC(=O)Nn1cnnc1)S(=O)(=O)c1ccccc1
e) O=C1N(Cc2cccnc2)C[C@@H]2C[C@@H](c3ccc4nonc4c3)N3CCC[C@@]123
Answer: e. O=C1N(Cc2cccnc2)C[C@@H]2C[C@@H](c3ccc4nonc4c3)N3CCC[C@@]123
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1N(Cc2cccnc2)C[C@@H]2C[C@@H](c3ccc4nonc4c3)N3CCC[C@@]123
O=C1N(Cc2cccnc2)C[C@@H]2C[C@@H](c3ccc4nonc4c3)N3CCC[C@@]123
(1S,5S,7S)-7-(2,1,3-benzoxadiazol-5-yl)-3-(pyridin-3-ylmethyl)-3,8-diazatricyclo[6.3.0.01,5]undecan-2-one