Task: Answer the MCQ question.
Question: Which drug has a -4.492\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CCOc1ccc(NC(=O)CN2C(=O)C3CC=CCC3C2=O)cc1
[b] COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)N(C)Cc1ccc(OC)c(OC)c1OC
[c] Cc1cccc(C)c1NC(=O)CSc1ncnc2nc[nH]c12
[d] COc1ccc([C@H]2CC(=O)C=C(c3ccc4ccccc4c3)C2)cc1
[e] CCN(CC)CCNC(=S)Nc1ccc(Cl)cc1
Answer: b. COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)N(C)Cc1ccc(OC)c(OC)c1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)N(C)Cc1ccc(OC)c(OC)c1OC
COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(=O)N(C)Cc1ccc(OC)c(OC)c1OC
5-(azepan-1-ylsulfonyl)-2-methoxy-N-methyl-N-[(2,3,4-trimethoxyphenyl)methyl]benzamide