Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 2.032\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
[a] O=C(c1cc(-c2ccco2)nc2ccccc12)N(Cc1nnc(-c2ccc(Cl)cc2)o1)C1CC1
[b] Cc1nn(C)c(C(=O)NNC(=S)NC2CCCCC2)c1Br
[c] Cc1cc(Cl)c(S(=O)(=O)N2CCSCC2)cc1OCC(=O)NC1CCCCC1
[d] COc1ccc(C2=NO[C@@H]3[C@@H]4C[C@@H]([C@H]5C(=O)N(C)C(=O)[C@@H]45)[C@H]23)cc1
Answer: d. COc1ccc(C2=NO[C@@H]3[C@@H]4C[C@@H]([C@H]5C(=O)N(C)C(=O)[C@@H]45)[C@H]23)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2=NO[C@@H]3[C@@H]4C[C@@H]([C@H]5C(=O)N(C)C(=O)[C@@H]45)[C@H]23)cc1
COc1ccc(C2=NO[C@@H]3[C@@H]4C[C@@H]([C@H]5C(=O)N(C)C(=O)[C@@H]45)[C@H]23)cc1
(1R,2R,6R,7R,8R,12S)-5-(4-methoxyphenyl)-10-methyl-3-oxa-4,10-diazatetracyclo[5.5.1.02,6.08,12]tridec-4-ene-9,11-dione