Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 8.453\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1nc2ccc(-c3nc4ccccc4o3)cc2[nH]1
b) COc1ccc(N2C(=O)CC(Sc3ncccc3C(=O)O)C2=O)cc1
c) C=CCN(C(=O)C1CC(=O)N(C2CCCC2)C1)c1nc(-c2ccc(S(C)(=O)=O)cc2)cs1
d) CC1(C)CC(c2csc(N)n2)CCO1
e) CC1(C)CC(=O)C=C(Nc2ccccc2N)C1
Answer: c. C=CCN(C(=O)C1CC(=O)N(C2CCCC2)C1)c1nc(-c2ccc(S(C)(=O)=O)cc2)cs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C=CCN(C(=O)C1CC(=O)N(C2CCCC2)C1)c1nc(-c2ccc(S(C)(=O)=O)cc2)cs1
C=CCN(C(=O)C1CC(=O)N(C2CCCC2)C1)c1nc(-c2ccc(S(C)(=O)=O)cc2)cs1
1-cyclopentyl-N-[4-(4-methylsulfonylphenyl)-1,3-thiazol-2-yl]-5-oxo-N-prop-2-enylpyrrolidine-3-carboxamide