Task: Answer the multiple-choice question.
Question: Which drug exhibits a 1.842\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1cc(OC)c(OC)cc1CN1CCN(S(=O)(=O)c2ccc(F)cc2)CC1.O=C(O)C(=O)O
b. CNC(=O)c1cccc2nc3ccccc3nc12
c. COc1ccc(NC(=O)c2cc(S(=O)(=O)N(Cc3ccccc3)c3ccccc3)ccc2Cl)cn1
d. CCN(CC(=O)Nc1c(F)cccc1F)C(=O)/C=C/c1ccc(Br)s1
e. Cc1c(C(C)C)c(=O)n(-c2ccc(S(=O)(=O)NC(C)C)cc2)n1C
Answer: c. COc1ccc(NC(=O)c2cc(S(=O)(=O)N(Cc3ccccc3)c3ccccc3)ccc2Cl)cn1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)c2cc(S(=O)(=O)N(Cc3ccccc3)c3ccccc3)ccc2Cl)cn1
COc1ccc(NC(=O)c2cc(S(=O)(=O)N(Cc3ccccc3)c3ccccc3)ccc2Cl)cn1
5-[benzyl(phenyl)sulfamoyl]-2-chloro-N-(6-methoxypyridin-3-yl)benzamide