Problem statement: Answer the multiple-choice question.
Query: Which drug has a -22.899\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1c(-c2n[nH]c(=S)n2-c2ccc(C(F)(F)F)cc2)nnn1-c1ccccc1
b. CCOC(=O)C1(CCCc2ccccc2)CCN(C(=O)c2cc(C)nc(C)n2)CC1
c. CCN(Cc1cnn(C)c1)Cc1nc(C(c2ccccc2)c2ccccc2)no1
d. COc1ccc(C(=O)N2CCN(c3ccccc3OC)CC2)cc1
e. Cc1oc(-c2cc(F)ccc2F)nc1CN1CCC(C(=O)N2CCOCC2)CC1
Answer: e. Cc1oc(-c2cc(F)ccc2F)nc1CN1CCC(C(=O)N2CCOCC2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1oc(-c2cc(F)ccc2F)nc1CN1CCC(C(=O)N2CCOCC2)CC1
Cc1oc(-c2cc(F)ccc2F)nc1CN1CCC(C(=O)N2CCOCC2)CC1
[1-[[2-(2,5-difluorophenyl)-5-methyl-1,3-oxazol-4-yl]methyl]piperidin-4-yl]-morpholin-4-ylmethanone