Problem statement: Answer the multiple choice question.
Query: Which compound exhibits a -4.160\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1C(=O)OCC(=O)N1CC(C)OC(C)C1
b COC(=O)C1[C@H]2SC(C)(C)C(C(=O)OC)N2C(=O)N1Cc1nc2ccccc2s1
c O=C(CSc1nc2ccccc2[nH]1)Nc1cc(C(F)(F)F)ccc1N1CCOCC1
d Cc1cc(-c2csc(NC(=O)c3cc4ccccc4o3)n2)c(C)n1C
e O=C(Nc1cccc(C(=O)O)c1)/C(=C\c1ccc2c(c1)OCO2)NC(=O)c1ccccc1
Answer: b. COC(=O)C1[C@H]2SC(C)(C)C(C(=O)OC)N2C(=O)N1Cc1nc2ccccc2s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1[C@H]2SC(C)(C)C(C(=O)OC)N2C(=O)N1Cc1nc2ccccc2s1
COC(=O)C1[C@H]2SC(C)(C)C(C(=O)OC)N2C(=O)N1Cc1nc2ccccc2s1
dimethyl (7aR)-6-(1,3-benzothiazol-2-ylmethyl)-2,2-dimethyl-5-oxo-7,7a-dihydro-3H-imidazo[5,1-b][1,3]thiazole-3,7-dicarboxylate