Problem statement: Answer the MCQ question.
Query: Which compound has a -0.270\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCCn1c(SCC(=O)NC2CC2)nnc1-c1cccs1
b. CCc1ccc2[nH]c(=O)c(CN(CCN(C)C)C(=O)Nc3ccccc3OC)cc2c1
c. COc1ccccc1N1CCN(C2CCCN(C(=O)c3oc(C)cc3C)C2)CC1
d. O=C(NCc1nc2ccccc2[nH]1)c1cccc(S(=O)(=O)N2CCOCC2)c1
e. Cc1ccccc1N1C(=O)c2ccccc2NC1c1ccncc1
Answer: d. O=C(NCc1nc2ccccc2[nH]1)c1cccc(S(=O)(=O)N2CCOCC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCc1nc2ccccc2[nH]1)c1cccc(S(=O)(=O)N2CCOCC2)c1
O=C(NCc1nc2ccccc2[nH]1)c1cccc(S(=O)(=O)N2CCOCC2)c1
N-(1H-benzimidazol-2-ylmethyl)-3-morpholin-4-ylsulfonylbenzamide