Problem statement: Answer the multiple-choice question.
Question: Which compound has a 10.778\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCOC(=O)C1(CCCc2ccccc2)CCN(S(=O)(=O)N(C)C)CC1
b. Cc1c(C(=O)N2CCOCC2)c(S(=O)(=O)Nc2ccc(Br)cc2F)c(C)n1C
c. CCc1ccccc1N(CC(=O)N1CCCC1)S(C)(=O)=O
d. COc1ccc(OC)c(NC(=O)c2ccc3c(c2)C(=O)N(c2ccc(OC(C)=O)cc2)C3=O)c1
e. Oc1ccc(C[C@H]2CNCCN2CCC23CC4CC(CC(C4)C2)C3)cc1
Answer: d. COc1ccc(OC)c(NC(=O)c2ccc3c(c2)C(=O)N(c2ccc(OC(C)=O)cc2)C3=O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OC)c(NC(=O)c2ccc3c(c2)C(=O)N(c2ccc(OC(C)=O)cc2)C3=O)c1
COc1ccc(OC)c(NC(=O)c2ccc3c(c2)C(=O)N(c2ccc(OC(C)=O)cc2)C3=O)c1
[4-[5-[(2,5-dimethoxyphenyl)carbamoyl]-1,3-dioxoisoindol-2-yl]phenyl] acetate