Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -14.189\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C(Cc1ccc(Br)cc1)NCCc1ccc(F)cc1
b) O=C(Nc1ccnn1C1CCN(Cc2cccc(O)c2)CC1)C1CCCC1
c) C=C1c2cccc(O)c2C(O)=C2C(=O)[C@]3(O)C(O)=C(C(N)=O)C(=O)[C@@H](N(C)C)[C@@H]3[C@@H](O)[C@H]12.Cl
d) O=C(Nc1ccc2c(c1)OCO2)c1cccc(S(=O)(=O)N2CCCC2)c1
e) Brc1ccc(CNCC2CCCO2)cc1
Answer: b. O=C(Nc1ccnn1C1CCN(Cc2cccc(O)c2)CC1)C1CCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1ccnn1C1CCN(Cc2cccc(O)c2)CC1)C1CCCC1
O=C(Nc1ccnn1C1CCN(Cc2cccc(O)c2)CC1)C1CCCC1
N-[2-[1-[(3-hydroxyphenyl)methyl]piperidin-4-yl]pyrazol-3-yl]cyclopentanecarboxamide