Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a 15.479\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: Cn1c(=O)n(Cc2ccccc2Br)c2ccccc21
b: O=C1CCN(Cc2ccccc2)CCN1[C@H](CSc1ccccc1)c1ccccc1
c: CN(C(=O)CC1C(=O)NCCN1Cc1cccc(C(F)(F)F)c1)C1CCOCC1
d: Oc1ccccc1CNc1ncc(Br)cc1Br
e: CCN(CC)S(=O)(=O)c1ccc2c(c1)CC(C(=O)N1CCCC1)N2C(C)=O
Answer: c. CN(C(=O)CC1C(=O)NCCN1Cc1cccc(C(F)(F)F)c1)C1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(C(=O)CC1C(=O)NCCN1Cc1cccc(C(F)(F)F)c1)C1CCOCC1
CN(C(=O)CC1C(=O)NCCN1Cc1cccc(C(F)(F)F)c1)C1CCOCC1
N-methyl-N-(oxan-4-yl)-2-[3-oxo-1-[[3-(trifluoromethyl)phenyl]methyl]piperazin-2-yl]acetamide