Problem statement: Answer the MCQ question.
Question: Which compound has a 0.725\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccc(NC(=O)CSc2nc(N)c3cc4c(nc3n2)CCCC4)cc1
b) COC(=O)[C@@H](NC(=O)c1cc(COc2cncc(Cl)c2)on1)c1ccccc1
c) CC1CCCN(C(=O)CSc2nnc(-c3ccco3)n2C)C1
d) CCOC(=O)Cc1csc(/N=C/c2c(O)n(-c3ccc(C)cc3C)c(=O)c3ccccc23)n1
e) COc1ccc(-c2nnc(SCC(=O)N3CCCC3)o2)c(OC)c1
Answer: d. CCOC(=O)Cc1csc(/N=C/c2c(O)n(-c3ccc(C)cc3C)c(=O)c3ccccc23)n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)Cc1csc(/N=C/c2c(O)n(-c3ccc(C)cc3C)c(=O)c3ccccc23)n1
CCOC(=O)Cc1csc(/N=C/c2c(O)n(-c3ccc(C)cc3C)c(=O)c3ccccc23)n1
ethyl 2-[2-[(E)-[2-(2,4-dimethylphenyl)-3-hydroxy-1-oxoisoquinolin-4-yl]methylideneamino]-1,3-thiazol-4-yl]acetate