Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -0.445\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CCOC(=O)N1CCN(C(=O)c2ccc3c(c2)NC(=O)/C(=C\c2cccc(C)c2)S3)CC1
b.) COc1ccc(CSc2nnnn2-c2ccc(O)cc2)cc1F
c.) O=C(NCCCn1ccnc1)c1ccc(OCC(F)(F)F)cc1
d.) COc1cccc(NC(=O)C(Sc2nc3ccccc3c(=O)n2CC(C)C)c2ccccc2)c1
e.) CCOC(=O)c1cc(C)sc1NC(=S)Nc1ccccc1
Answer: a. CCOC(=O)N1CCN(C(=O)c2ccc3c(c2)NC(=O)/C(=C\c2cccc(C)c2)S3)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(C(=O)c2ccc3c(c2)NC(=O)/C(=C\c2cccc(C)c2)S3)CC1
CCOC(=O)N1CCN(C(=O)c2ccc3c(c2)NC(=O)/C(=C\c2cccc(C)c2)S3)CC1
ethyl 4-[(2E)-2-[(3-methylphenyl)methylidene]-3-oxo-4H-1,4-benzothiazine-6-carbonyl]piperazine-1-carboxylate