Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 8.449\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COC(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1
(b) N/C(=N\OC(=O)c1cccc(Cl)c1)c1ccncc1
(c) c1ccc(C[C@H]2CNCCN2CCCCC2CCCCC2)cc1
(d) CC1C(=O)N2CCCc3cc(S(=O)(=O)N(C)CCC#N)cc1c32
(e) O=C(O)C(=O)O.O=S(=O)(c1cccc(C(F)(F)F)c1)N(CCCN1CCOCC1)Cc1cccs1
Answer: a. COC(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1
COC(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1
methyl1-benzylsulfonylpiperidine-4-carboxylate