Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 15.593\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCOc1cccc(C2/C(=C(/O)c3ccc4c(c3)CC(C)O4)C(=O)C(=O)N2CCCn2ccnc2)c1
b. COC(=O)C1=C(C)Nc2ccc(C)cc2S1
c. CC(C)CN(C(=O)CN(C)C(=O)c1ccco1)c1c(N)n(CC(C)C)c(=O)[nH]c1=O
d. COCCNC(=O)NC12CC3CC(CC(C3)C1)C2
e. O=C(COC(=O)C1CC2C=CC1C2)NCc1ccco1
Answer: c. CC(C)CN(C(=O)CN(C)C(=O)c1ccco1)c1c(N)n(CC(C)C)c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)CN(C(=O)CN(C)C(=O)c1ccco1)c1c(N)n(CC(C)C)c(=O)[nH]c1=O
CC(C)CN(C(=O)CN(C)C(=O)c1ccco1)c1c(N)n(CC(C)C)c(=O)[nH]c1=O
N-[2-[[6-amino-1-(2-methylpropyl)-2,4-dioxopyrimidin-5-yl]-(2-methylpropyl)amino]-2-oxoethyl]-N-methylfuran-2-carboxamide