Problem statement: Answer the MCQ question.
Question: Which compound has a -1.287\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=[N+]([O-])c1ccc(NCc2ccc(Cl)cc2)c2ccncc12
b.) CCCNC(=O)C1=C(C)C(=O)OC12CCC(C)CC2
c.) Cc1ccccc1NC(=S)Nc1ccc2cn[nH]c2c1
d.) CC(=O)c1cccc(N(C(=O)c2ccco2)C(C(=O)NC2CCCC2)c2ccc(N3CCOCC3)cc2)c1
e.) COc1ccc(N2CCN(S(=O)(=O)c3cccc4cccnc34)CC2)cc1
Answer: e. COc1ccc(N2CCN(S(=O)(=O)c3cccc4cccnc34)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(S(=O)(=O)c3cccc4cccnc34)CC2)cc1
COc1ccc(N2CCN(S(=O)(=O)c3cccc4cccnc34)CC2)cc1
8-[4-(4-methoxyphenyl)piperazin-1-yl]sulfonylquinoline