Problem statement: Answer the MCQ question.
Query: Which drug has a -11.423\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COc1ccc2nc(SCC(=O)Nc3ccccc3C)[nH]c2c1
b.) O=C(CSc1nccc(=O)[nH]1)Nc1ccc(S(=O)(=O)N2CCOCC2)cc1
c.) O=[N+]([O-])c1cc2c(c(CSc3nnc(Nc4ccccc4)s3)c1)OCOC2
d.) CCOC(=O)N1CCN(S(=O)(=O)c2ccc(OC)c(OC)c2)CC1
e.) Cc1ccc(C(=O)NCC(c2ccc(F)cc2)N2CCOCC2)cc1
Answer: d. CCOC(=O)N1CCN(S(=O)(=O)c2ccc(OC)c(OC)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(S(=O)(=O)c2ccc(OC)c(OC)c2)CC1
CCOC(=O)N1CCN(S(=O)(=O)c2ccc(OC)c(OC)c2)CC1
ethyl 4-(3,4-dimethoxyphenyl)sulfonylpiperazine-1-carboxylate