Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -2.190\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CCC(Oc1cc(Cl)ccc1Cl)C(=O)N1CCCN(C)CC1
b.) COc1cc(C(=O)NCC(=O)Nc2c(C)cccc2C)ccc1OCc1ccccc1
c.) O=[N+]([O-])c1ccc(Cl)c(C2Nc3cccc4cccc(c34)N2)c1
d.) Nc1c(C(=O)Nc2ccccc2F)sc2nc(-c3cccnc3)ccc12
e.) O=C(CCCNS(=O)(=O)c1ccc(Br)cc1)N1CC[C@@]2(O)CCCC[C@H]2C1
Answer: e. O=C(CCCNS(=O)(=O)c1ccc(Br)cc1)N1CC[C@@]2(O)CCCC[C@H]2C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCCNS(=O)(=O)c1ccc(Br)cc1)N1CC[C@@]2(O)CCCC[C@H]2C1
O=C(CCCNS(=O)(=O)c1ccc(Br)cc1)N1CC[C@@]2(O)CCCC[C@H]2C1
N-[4-[(4aS,8aS)-4a-hydroxy-1,3,4,5,6,7,8,8a-octahydroisoquinolin-2-yl]-4-oxobutyl]-4-bromobenzenesulfonamide