Task: Answer the multiple-choice question.
Query: Which drug has a -33.111\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COC(=O)c1cccc(NC(=O)c2ccccc2)c1
b) COC(=O)C1=C(O)CSC1=Nc1ccccc1
c) Cc1ccc(C(=O)c2ccccc2C(=O)OCC(=O)N2C(C)CCCC2C)cc1
d) CC(=O)NS(=O)(=O)c1ccc(NC(=O)CCC(=O)Oc2ccc(C)cc2)cc1
e) CN(CC(=O)Nc1ccccc1Br)C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1
Answer: e. CN(CC(=O)Nc1ccccc1Br)C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(CC(=O)Nc1ccccc1Br)C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1
CN(CC(=O)Nc1ccccc1Br)C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1
N-[2-(2-bromoanilino)-2-oxoethyl]-2-[4-[(4-chlorophenyl)methyl]piperazin-1-yl]-N-methylacetamide