Problem statement: Answer the multiple-choice question.
Question: Which drug has a 21.830\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a CCc1cccc(CC)c1NC(=S)Nc1cccc(Cl)c1Cl
b CS(=O)(=O)N(Cc1ccccc1)c1ccc(C(=O)Nc2ccc(C(N)=O)cc2)cc1
c COc1ccc(CNC(=O)C(=O)NC2CCC(C)CC2)cc1
d CN(Cc1ccccc1)C(=O)c1nc[nH]c1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1
Answer: d. CN(Cc1ccccc1)C(=O)c1nc[nH]c1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(Cc1ccccc1)C(=O)c1nc[nH]c1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1
CN(Cc1ccccc1)C(=O)c1nc[nH]c1C(=O)N1CCN(C(=O)OC(C)(C)C)CC1
tert-butyl 4-[4-[benzyl(methyl)carbamoyl]-1H-imidazole-5-carbonyl]piperazine-1-carboxylate