Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -16.900\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COC(=O)C1=C(N)Oc2c(oc(CO)cc2=O)C1c1ccc(F)cc1
[b] O=C(CCc1nc(-c2ccccc2Cl)no1)NCCc1ccccc1
[c] O=C(c1cc(C2CC2)on1)N1CCCC(N2CCN(c3ccc(F)cc3)CC2)C1
[d] COC(=O)CNC(c1ccccc1)c1cc(Br)ccc1NC(=O)CNC(=O)OCc1ccccc1
[e] CCOC(=O)N1CCN(C2=CC(=O)OC23CCCCC3)CC1
Answer: c. O=C(c1cc(C2CC2)on1)N1CCCC(N2CCN(c3ccc(F)cc3)CC2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1cc(C2CC2)on1)N1CCCC(N2CCN(c3ccc(F)cc3)CC2)C1
O=C(c1cc(C2CC2)on1)N1CCCC(N2CCN(c3ccc(F)cc3)CC2)C1
(5-cyclopropyl-1,2-oxazol-3-yl)-[3-[4-(4-fluorophenyl)piperazin-1-yl]piperidin-1-yl]methanone