Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -7.914\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCC1CCCCN1CCCNC(=O)c1ccc(CS(=O)(=O)Cc2ccccc2F)o1
b) COc1ccc(OC)c(CNC(=O)C2CCN(S(=O)(=O)N3CCC(C)CC3)CC2)c1
c) CSc1nc2ccc(NC(=O)c3ccco3)cc2s1
d) CCCOC(=O)CSC1=C(C#N)C(c2ccc3c(c2)OCO3)CC(=O)N1
e) O=C(N/N=C1/CCSC1)c1cc(Br)ccc1O
Answer: b. COc1ccc(OC)c(CNC(=O)C2CCN(S(=O)(=O)N3CCC(C)CC3)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OC)c(CNC(=O)C2CCN(S(=O)(=O)N3CCC(C)CC3)CC2)c1
COc1ccc(OC)c(CNC(=O)C2CCN(S(=O)(=O)N3CCC(C)CC3)CC2)c1
N-[(2,5-dimethoxyphenyl)methyl]-1-[(4-methylpiperidin-1-yl)sulfonyl]piperidine-4-carboxamide