Problem statement: Answer the multiple-choice question.
Question: Which drug has a -15.685\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
(a) CCOC(=O)C(NC(C)=O)(Nc1ccc(S(=O)(=O)Nc2ccncn2)cc1)C(F)(F)F
(b) O=C(NNC(=O)c1ccccc1Cl)c1cc2cc(OC(F)(F)F)ccc2[nH]1
(c) O=C(OCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)c1cccc(OC(F)F)c1
Answer: c. O=C(OCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)c1cccc(OC(F)F)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(OCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)c1cccc(OC(F)F)c1
O=C(OCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)c1cccc(OC(F)F)c1
[2-[4-(4-chlorophenyl)sulfonylpiperazin-1-yl]-2-oxoethyl]5-(difluoromethoxy)benzoate