Problem statement: Answer the multiple-choice question.
Query: Which drug has a -3.639\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a Cc1ccc(N(Cc2ccccc2)C(=O)c2cccc(S(=O)(=O)N3CCN(C)CC3)c2)cc1
b O=C(c1ccc(Nc2cccc(C(F)(F)F)c2)nc1)N1CCCC1
c Cc1cccc(N2CCN(C(=O)CSCc3c(C)noc3C)CC2)c1C
d Cc1occc1C(=O)N1CCN(c2ccccc2)CC1
e CCC(C)(C)C1CCc2[nH]nc(C(=O)NC3CCCCC3)c2C1
Answer: b. O=C(c1ccc(Nc2cccc(C(F)(F)F)c2)nc1)N1CCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccc(Nc2cccc(C(F)(F)F)c2)nc1)N1CCCC1
O=C(c1ccc(Nc2cccc(C(F)(F)F)c2)nc1)N1CCCC1
pyrrolidin-1-yl-[6-[3-(trifluoromethyl)anilino]pyridin-3-yl]methanone