Problem statement: Answer the multiple-choice question.
Question: Which compound has a -12.253\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] O=C(Nc1ccc(Cl)cc1)N1CCOCC1
[b] NC(=O)C1CCN(c2nc(C3CC3)nc3c2nnn3Cc2ccccc2)CC1
[c] COc1ccc(C(=O)N2CCC(C(=O)Nc3ccc(C)cc3)CC2)cc1
[d] O=C(Nc1ccccc1Cl)C1CCCN(S(=O)(=O)c2cccc3cccnc23)C1
[e] Cc1ccc(-c2c(C(=O)NC(C)C)oc(=O)c3ccccc23)cc1
Answer: b. NC(=O)C1CCN(c2nc(C3CC3)nc3c2nnn3Cc2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
NC(=O)C1CCN(c2nc(C3CC3)nc3c2nnn3Cc2ccccc2)CC1
NC(=O)C1CCN(c2nc(C3CC3)nc3c2nnn3Cc2ccccc2)CC1
1-(3-benzyl-5-cyclopropyltriazolo[4,5-d]pyrimidin-7-yl)piperidine-4-carboxamide