Problem statement: Answer the multiple-choice question.
Query: Which compound has a 12.385\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] N#Cc1c(-c2ccccc2)nc(-c2ccccc2)nc1N1CCOCC1
[b] COc1ccc(CNC(=O)CCc2cc(OC)c(OC)c(OC)c2)cc1
[c] COc1ccc(C2c3[nH]c4ccccc4c3C[C@H]3C(=O)N(CCCO)CC(=O)N23)c(OC)c1
[d] COc1ccc(/C=N\NC(=O)c2cccc([N+](=O)[O-])c2)cc1Cn1cc([N+](=O)[O-])cn1
Answer: b. COc1ccc(CNC(=O)CCc2cc(OC)c(OC)c(OC)c2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)CCc2cc(OC)c(OC)c(OC)c2)cc1
COc1ccc(CNC(=O)CCc2cc(OC)c(OC)c(OC)c2)cc1
N-[(4-methoxyphenyl)methyl]-3-(3,4,5-trimethoxyphenyl)propanamide