Task: Answer the multiple-choice question.
Query: What is the human ether-à-go-go related gene (hERG) inhibition at 1uM of a compound with the SMILES COC(=O)c1ccc(CSc2nc(C)nc3c2c(=O)n(C)c(=O)n3C)o1?
Constraint: You must return none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: 16.017
b: -31.386
c: 17.002
d: -21.016
e: 13.113
Answer: a. 16.017\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
COC(=O)c1ccc(CSc2nc(C)nc3c2c(=O)n(C)c(=O)n3C)o1
COC(=O)c1ccc(CSc2nc(C)nc3c2c(=O)n(C)c(=O)n3C)o1
methyl 5-[(1,3,7-trimethyl-2,4-dioxopyrimido[4,5-d]pyrimidin-5-yl)sulfanylmethyl]furan-2-carboxylate