Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 10.410\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. COc1ccc(C2N(C(=O)N(C)C)CCN2S(=O)(=O)c2ccc(OC)cc2)cc1
b. COc1cccc(CNC(=O)CN2C(=O)c3ccccc3S2(=O)=O)c1
c. COC(=O)c1ccc(CSc2nc(C(F)F)cc(C)c2C#N)o1
d. C/C(=N\Nc1ccc(C(F)(F)F)cn1)c1ccncc1
Answer: c. COC(=O)c1ccc(CSc2nc(C(F)F)cc(C)c2C#N)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(CSc2nc(C(F)F)cc(C)c2C#N)o1
COC(=O)c1ccc(CSc2nc(C(F)F)cc(C)c2C#N)o1
methyl 5-[[3-cyano-6-(difluoromethyl)-4-methylpyridin-2-yl]sulfanylmethyl]furan-2-carboxylate