Problem statement: Answer the multiple-choice question.
Question: Which drug has a 6.454\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CCC(=O)c1ccc(OC(=O)N2CCOCC2)cc1
b Cc1ccc(OCc2ccc(C(=O)Nc3nccs3)o2)cc1
c COc1ccc(NC(=O)CN2CCN(CC(=O)Nc3ccc(F)cc3)CC2)cc1Cl
d O=C(CSc1nc(-c2ccccc2)cc(=O)[nH]1)NCc1ccc2c(c1)OCO2
e CCOc1ccc(-n2cc(C(=O)N3CCCCCC3)c3cc(OC)c(OC)cc3c2=O)cc1
Answer: d. O=C(CSc1nc(-c2ccccc2)cc(=O)[nH]1)NCc1ccc2c(c1)OCO2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CSc1nc(-c2ccccc2)cc(=O)[nH]1)NCc1ccc2c(c1)OCO2
O=C(CSc1nc(-c2ccccc2)cc(=O)[nH]1)NCc1ccc2c(c1)OCO2
N-(1,3-benzodioxol-5-ylmethyl)-2-[(6-oxo-4-phenyl-1H-pyrimidin-2-yl)sulfanyl]acetamide