Task: Answer the multiple choice question.
Question: Which drug has a -17.523\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a O=C(O)CN1CCN(Cc2ccc(Cl)cc2)C1=O
b CN(C(=O)CCNC(=O)Cn1cnc2ccccc2c1=O)c1ccc(F)cc1
c COc1ccc(CNC(=O)C(C)Sc2nc3ccccc3c(=O)n2CC2CCCO2)cc1
d CCn1c(CN2CCN(c3cccc(C)c3C)CC2)n[nH]c1=S
e Cc1ccnc(NC(=O)CC(NC(=O)c2ccccc2Cl)c2ccccc2)c1
Answer: c. COc1ccc(CNC(=O)C(C)Sc2nc3ccccc3c(=O)n2CC2CCCO2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C(C)Sc2nc3ccccc3c(=O)n2CC2CCCO2)cc1
COc1ccc(CNC(=O)C(C)Sc2nc3ccccc3c(=O)n2CC2CCCO2)cc1
N-[(4-methoxyphenyl)methyl]-2-[4-oxo-3-(oxolan-2-ylmethyl)quinazolin-2-yl]sulfanylpropanamide