Problem statement: Answer the multiple-choice question.
Question: Which compound has a 2.126\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccc(C)cc1N(C(=O)c1ccco1)C(C(=O)NC1CCCC1)c1cccs1
(b) O=[N+]([O-])c1ccc(-c2ccc(/C=N/Nc3nc(NCc4ccccc4)nc(N4CCOCC4)n3)o2)cc1
(c) CCOC(=O)/C(=N\Nc1ncnc2ccccc12)c1ccc(OC)cc1
(d) COc1cccc(CNC(=O)CC(NC(C)=O)c2ccccc2)c1
(e) O=[N+]([O-])c1cc(-c2cnc3ccccc3n2)ccc1Oc1ccc(F)cc1
Answer: d. COc1cccc(CNC(=O)CC(NC(C)=O)c2ccccc2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CNC(=O)CC(NC(C)=O)c2ccccc2)c1
COc1cccc(CNC(=O)CC(NC(C)=O)c2ccccc2)c1
3-acetamido-N-[(3-methoxyphenyl)methyl]-3-phenylpropanamide