Problem statement: Answer the MCQ question.
Question: Which compound has a 1.215\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CC(C)(C)NC(=O)COc1ccc(-c2ccccc2)cc1
b. O=C(Cn1nnc(-c2ccccc2)n1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
c. O=S(=O)(C=C(c1ccccc1)c1ccccc1)c1ccccc1
d. CSc1sc(C(=O)NNC(C)=O)c2c1C1(CCC2)SCCS1
e. COc1ccc(C(C)=O)cc1COC(=O)c1ccc(C)c(S(=O)(=O)N2CCOCC2)c1
Answer: e. COc1ccc(C(C)=O)cc1COC(=O)c1ccc(C)c(S(=O)(=O)N2CCOCC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(C)=O)cc1COC(=O)c1ccc(C)c(S(=O)(=O)N2CCOCC2)c1
COc1ccc(C(C)=O)cc1COC(=O)c1ccc(C)c(S(=O)(=O)N2CCOCC2)c1
(5-acetyl-2-methoxyphenyl)methyl 4-methyl-3-morpholin-4-ylsulfonylbenzoate