Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -12.792\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a O=C(CSc1ccccn1)Nc1nncs1
b NC(N)=NN=C1c2ccccc2-c2ccccc21
c CCOC(=O)C1CCN(C(=O)CCNC(=O)Cn2ccc3ccccc3c2=O)CC1
d COc1ccccc1CC(=O)c1ccc(OCc2ccccc2)cc1
e COc1ccc(S(=O)(=O)N(CCc2ccccc2)CC(=O)NCCCO)cc1
Answer: e. COc1ccc(S(=O)(=O)N(CCc2ccccc2)CC(=O)NCCCO)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)N(CCc2ccccc2)CC(=O)NCCCO)cc1
COc1ccc(S(=O)(=O)N(CCc2ccccc2)CC(=O)NCCCO)cc1
N-(3-hydroxypropyl)-2-[(4-methoxyphenyl)sulfonyl-(2-phenylethyl)amino]acetamide