Problem statement: Answer the multiple choice question.
Query: Which compound exhibits a -1.222\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
(a) O=C(CCCN1C(=O)/C(=C\c2cccs2)SC1=S)Nc1ccc(O)cc1
(b) COc1cccc(NC(=O)Cn2c(CCC(=O)O)ccc2-c2cccs2)c1
(c) COc1ccc(OC)c(CN2CCN(C(=O)CNC(=O)c3ccc(C(C)(C)C)cc3)CC2)c1
Answer: c. COc1ccc(OC)c(CN2CCN(C(=O)CNC(=O)c3ccc(C(C)(C)C)cc3)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OC)c(CN2CCN(C(=O)CNC(=O)c3ccc(C(C)(C)C)cc3)CC2)c1
COc1ccc(OC)c(CN2CCN(C(=O)CNC(=O)c3ccc(C(C)(C)C)cc3)CC2)c1
4-tert-butyl-N-[2-[4-[(2,5-dimethoxyphenyl)methyl]piperazin-1-yl]-2-oxoethyl]benzamide