Problem statement: Answer the multiple-choice question.
Question: Which drug has a -20.257\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
(a) O=C(CNC(=O)c1ccco1)NCC(=O)OCc1ccccc1Br
(b) COC(=O)c1ccccc1NC(=O)c1cnn2c(C)cc(C)nc12
(c) O=C(c1ccc(N2CCCS2(=O)=O)cc1)N1CCN(c2ccccc2)CC1
(d) Cc1ccc(N2Cc3ccccc3C2=S)cc1
Answer: b. COC(=O)c1ccccc1NC(=O)c1cnn2c(C)cc(C)nc12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccccc1NC(=O)c1cnn2c(C)cc(C)nc12
COC(=O)c1ccccc1NC(=O)c1cnn2c(C)cc(C)nc12
methyl 2-[(5,7-dimethylpyrazolo[1,5-a]pyrimidine-3-carbonyl)amino]benzoate