Problem statement: Answer the multiple choice question.
Question: Which compound has a 13.728\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C1CCN(CCc2ccccc2)CCN1CCSc1ccc(Br)cc1
b.) Cc1sc(NC(=S)Nc2ccc(F)cc2)c(C(N)=O)c1C
c.) COc1cccc(CC(=O)N[C@@H](CCSC)c2nc3ccccc3[nH]2)c1
d.) CC(=O)c1ccc(S(=O)(=O)NCCC(=O)N2CCN(c3ccccn3)CC2)cc1
e.) FC(F)(F)c1ccc(C2[C@H]3CN(Cc4cccnc4)[C@H](c4ccccc4)C34CC2(c2cccnc2)C4)cc1
Answer: e. FC(F)(F)c1ccc(C2[C@H]3CN(Cc4cccnc4)[C@H](c4ccccc4)C34CC2(c2cccnc2)C4)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
FC(F)(F)c1ccc(C2[C@H]3CN(Cc4cccnc4)[C@H](c4ccccc4)C34CC2(c2cccnc2)C4)cc1
FC(F)(F)c1ccc(C2[C@H]3CN(Cc4cccnc4)[C@H](c4ccccc4)C34CC2(c2cccnc2)C4)cc1
(2S,5R)-2-phenyl-7-pyridin-3-yl-3-(pyridin-3-ylmethyl)-6-[4-(trifluoromethyl)phenyl]-3-azatricyclo[5.1.1.01,5]nonane