Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 0.381\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCCC1(CCC)C(=O)NC(=NCc2ccccc2)NC1=O
(b) COC(=O)CSc1nccc(-c2cccs2)n1
(c) CCCc1cc2nnc(SCC(=O)N(C)C3CCCCC3)n2c(N)n1
(d) COc1cccc(CN2CC(C(=O)NCCN3CCOCC3)CCC2=O)c1
(e) S=c1[nH]nc(-c2cccc(Cl)c2)n1/N=C/c1ccco1
Answer: d. COc1cccc(CN2CC(C(=O)NCCN3CCOCC3)CCC2=O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CN2CC(C(=O)NCCN3CCOCC3)CCC2=O)c1
COc1cccc(CN2CC(C(=O)NCCN3CCOCC3)CCC2=O)c1
1-[(3-methoxyphenyl)methyl]-N-(2-morpholin-4-ylethyl)-6-oxopiperidine-3-carboxamide