Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a 6.425\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CN1CCN(Cc2coc3c(Cl)cc(Cl)cc3c2=O)CC1.O=C(O)C(=O)O
(b) COc1cc(NC(=O)CCc2nnc3ccc(N4CCCC4)nn23)cc(OC)c1OC
(c) CC(=O)Nc1cccc(Nc2nc(-c3cccs3)nc3ccccc23)c1
(d) CCOC(=O)N1CCN(c2nc(-c3ccccc3)c3ccccc3n2)CC1
(e) O=C(CCc1nc2ccccc2c(=O)[nH]1)Nc1cc(C(F)(F)F)ccc1N1CCCC1
Answer: e. O=C(CCc1nc2ccccc2c(=O)[nH]1)Nc1cc(C(F)(F)F)ccc1N1CCCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCc1nc2ccccc2c(=O)[nH]1)Nc1cc(C(F)(F)F)ccc1N1CCCC1
O=C(CCc1nc2ccccc2c(=O)[nH]1)Nc1cc(C(F)(F)F)ccc1N1CCCC1
3-(4-oxo-3H-quinazolin-2-yl)-N-[2-pyrrolidin-1-yl-5-(trifluoromethyl)phenyl]propanamide