Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 8.407\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] OCCC1CN(Cc2cnc(-c3ccc(Cl)cc3)nc2)CCN1C1CCCC1
[b] COCCn1c(N)c(N(Cc2ccccc2)C(=O)c2ccc(-c3ccc(Cl)cc3)o2)c(=O)[nH]c1=O
[c] O=C(NCCc1ccccn1)C1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
[d] CC(C)c1ccc(CN(C(=O)C2COc3ccccc3O2)C2CCS(=O)(=O)C2)cc1
[e] CCOC(=O)N1CCN(C(=O)CCc2ccc(S(=O)(=O)NCC(C)C)cc2)CC1
Answer: d. CC(C)c1ccc(CN(C(=O)C2COc3ccccc3O2)C2CCS(=O)(=O)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)c1ccc(CN(C(=O)C2COc3ccccc3O2)C2CCS(=O)(=O)C2)cc1
CC(C)c1ccc(CN(C(=O)C2COc3ccccc3O2)C2CCS(=O)(=O)C2)cc1
N-(1,1-dioxothiolan-3-yl)-N-[(4-propan-2-ylphenyl)methyl]-2,3-dihydro-1,4-benzodioxine-3-carboxamide