Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 16.909\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cn1ncc(Br)c1C(=O)NC1CCCC1
b) CNC(=O)c1ccc(-c2cc(C(F)(F)F)nn2C)s1
c) Cc1ccc(N2CC(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCC3)CC2=O)cc1
d) Cc1ccc(-n2c(N)c(S(=O)(=O)c3ccccc3)c3nc4ccccc4nc32)cc1
e) CCn1c(SCC(=O)Nc2ccc(F)cc2)nnc1C1CC1
Answer: b. CNC(=O)c1ccc(-c2cc(C(F)(F)F)nn2C)s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CNC(=O)c1ccc(-c2cc(C(F)(F)F)nn2C)s1
CNC(=O)c1ccc(-c2cc(C(F)(F)F)nn2C)s1
N-methyl-5-[2-methyl-5-(trifluoromethyl)pyrazol-3-yl]thiophene-2-carboxamide