Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 10.325\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: CC[C@@]12C(=O)N(c3cccc(C)c3)C(=O)N1[C@H](c1ccc(OC)cc1)[C@@H]1C(=O)N(C(C)(C)C)C(=O)[C@@H]12
b: COc1ccc(C2C=C(c3ccc(C)c(C)c3)Nc3ncnn32)c(OC)c1OC
c: COc1cccc(Nc2nc(-c3ccccc3O)nc3ccccc23)c1
d: CCCn1c2ccccc2c2cnn(CC(=O)NCCN(C)C)c(=O)c21
Answer: a. CC[C@@]12C(=O)N(c3cccc(C)c3)C(=O)N1[C@H](c1ccc(OC)cc1)[C@@H]1C(=O)N(C(C)(C)C)C(=O)[C@@H]12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC[C@@]12C(=O)N(c3cccc(C)c3)C(=O)N1[C@H](c1ccc(OC)cc1)[C@@H]1C(=O)N(C(C)(C)C)C(=O)[C@@H]12
CC[C@@]12C(=O)N(c3cccc(C)c3)C(=O)N1[C@H](c1ccc(OC)cc1)[C@@H]1C(=O)N(C(C)(C)C)C(=O)[C@@H]12
(1S,2R,7S,8R)-10-tert-butyl-2-ethyl-7-(4-methoxyphenyl)-4-(3-methylphenyl)-4,6,10-triazatricyclo[6.3.0.02,6]undecane-3,5,9,11-tetrone