Problem statement: Answer the MCQ question.
Query: Which drug has a -8.434\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1ccc2[nH]c(C(=O)NCCCn3ccnc3)cc2c1
b: COc1ccc(/C(N)=N/OC(=O)N2CCOCC2)cc1
c: C#Cc1ccc(CN2CCC(C(=O)Nc3ccc(Oc4ccccc4)nc3)CC2)cc1
d: COc1cccc(CCNC(=O)c2cc(COc3c(F)cccc3F)on2)c1
e: Cc1ccc(/C=C/C(=O)NCc2ccco2)o1
Answer: d. COc1cccc(CCNC(=O)c2cc(COc3c(F)cccc3F)on2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CCNC(=O)c2cc(COc3c(F)cccc3F)on2)c1
COc1cccc(CCNC(=O)c2cc(COc3c(F)cccc3F)on2)c1
5-[(2,6-difluorophenoxy)methyl]-N-[2-(3-methoxyphenyl)ethyl]-1,2-oxazole-3-carboxamide