Problem statement: Answer the multiple choice question.
Question: Which compound has a 12.490\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: CCOc1ccc(N(C(C)C(=O)NC2CCCCCC2)S(C)(=O)=O)cc1
b: CC1(C)CC(c2nc(-c3ccc(Br)cc3)cs2)CCS1.Cl
c: CCOC(=O)C1CCCN(C(=O)c2ccc(Cl)cc2)C1
d: COc1cc(C(=O)NCCN2C(=O)S/C(=C\c3ccc(F)cc3)C2=O)ccc1OCC(=O)N1CCOCC1
e: O=C(O)c1nn(CC(=O)N2CCC(Cc3ccccc3)CC2)c(=O)c2ccccc12
Answer: d. COc1cc(C(=O)NCCN2C(=O)S/C(=C\c3ccc(F)cc3)C2=O)ccc1OCC(=O)N1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(C(=O)NCCN2C(=O)S/C(=C\c3ccc(F)cc3)C2=O)ccc1OCC(=O)N1CCOCC1
COc1cc(C(=O)NCCN2C(=O)S/C(=C\c3ccc(F)cc3)C2=O)ccc1OCC(=O)N1CCOCC1
N-[2-[(5Z)-5-[(4-fluorophenyl)methylidene]-2,4-dioxo-1,3-thiazolidin-3-yl]ethyl]-3-methoxy-4-(2-morpholin-4-yl-2-oxoethoxy)benzamide