Problem statement: Answer the multiple-choice question.
Query: Which drug has a -27.486\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1cccc2sc(N(CCCN(C)C)C(=O)c3ccc(S(=O)(=O)N4CCCc5ccccc54)cc3)nc12.Cl
[b] CCOc1ccc(N(CC(=O)Nc2ccccc2C(=O)NC(C)CC)S(C)(=O)=O)cc1
[c] Cc1csc(NC(=O)C2CCN(S(=O)(=O)c3ccc4c(c3)oc(=O)n4C)CC2)n1
[d] CCc1cccc2c(=O)c(C(=O)NCCN3CCOCC3)c[nH]c12
[e] Cn1c(Cc2ccc3c(c2)OCO3)nnc1SCC(=O)NC1CCCC1
Answer: c. Cc1csc(NC(=O)C2CCN(S(=O)(=O)c3ccc4c(c3)oc(=O)n4C)CC2)n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1csc(NC(=O)C2CCN(S(=O)(=O)c3ccc4c(c3)oc(=O)n4C)CC2)n1
Cc1csc(NC(=O)C2CCN(S(=O)(=O)c3ccc4c(c3)oc(=O)n4C)CC2)n1
1-[(3-methyl-2-oxo-1,3-benzoxazol-6-yl)sulfonyl]-N-(4-methyl-1,3-thiazol-2-yl)piperidine-4-carboxamide