Problem statement: Answer the multiple-choice question.
Query: Which drug has a 12.509\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) C=CCn1c(=O)c(C(=O)Nc2ccccc2O)c(O)c2ccccc21
(b) CCCCn1c(N)c(N(CCOC)C(=O)c2ccc(NC3CC3)c([N+](=O)[O-])c2)c(=O)[nH]c1=O
(c) CN(C)c1ccc(/C=C(\C#N)C(=O)OCC(=O)N(C)C2CCS(=O)(=O)C2)cc1
(d) CC1CC(C)CN(c2oc(-c3ccccc3Cl)nc2C#N)C1
(e) COC(=O)c1cc(S(=O)(=O)N2CCN(c3ccc(C(C)=O)cc3)CC2)cn1C
Answer: e. COC(=O)c1cc(S(=O)(=O)N2CCN(c3ccc(C(C)=O)cc3)CC2)cn1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1cc(S(=O)(=O)N2CCN(c3ccc(C(C)=O)cc3)CC2)cn1C
COC(=O)c1cc(S(=O)(=O)N2CCN(c3ccc(C(C)=O)cc3)CC2)cn1C
methyl 4-[4-(4-acetylphenyl)piperazin-1-yl]sulfonyl-1-methylpyrrole-2-carboxylate