Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -2.993\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) Cc1ccc(OCCC(=O)OCC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1
b.) CC(C)[C@H](NC(=O)c1ccccc1)C(=O)OCC(=O)c1ccc2c(c1)NC(=O)CO2
c.) COc1cc2c(cc1OC)C(c1ccccc1Br)NC(=O)C2
d.) COc1cc(OC)cc(-c2c(C#Cc3ccsc3)c3cc(-c4ccc(C(N)=O)cc4)ccc3n2C)c1
e.) CCOC(=O)Cc1csc(NC(=O)C(C)(C)C)n1
Answer: b. CC(C)[C@H](NC(=O)c1ccccc1)C(=O)OCC(=O)c1ccc2c(c1)NC(=O)CO2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)[C@H](NC(=O)c1ccccc1)C(=O)OCC(=O)c1ccc2c(c1)NC(=O)CO2
CC(C)[C@H](NC(=O)c1ccccc1)C(=O)OCC(=O)c1ccc2c(c1)NC(=O)CO2
[2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] (2S)-2-benzamido-3-methylbutanoate