Problem statement: Answer the multiple-choice question.
Question: Which compound has a 1.083\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) Cc1ccc(NC(=O)CCC(=O)c2cc(C)sc2C)nc1
(b) COc1cc2c(cc1OC)C(c1cccs1)N(C(=O)c1ccncc1)CC2
(c) CCN(CC)C(=O)COc1ccc2c(-c3ccccc3)cc(=O)oc2c1
(d) COc1ccc(CNc2nc(-c3ccccc3)nn2C(=O)c2ccc([N+](=O)[O-])cc2)cc1
(e) O=C1C=C(Nc2ccccc2)C(=O)c2ccccc21
Answer: b. COc1cc2c(cc1OC)C(c1cccs1)N(C(=O)c1ccncc1)CC2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc2c(cc1OC)C(c1cccs1)N(C(=O)c1ccncc1)CC2
COc1cc2c(cc1OC)C(c1cccs1)N(C(=O)c1ccncc1)CC2
(6,7-dimethoxy-1-thiophen-2-yl-3,4-dihydro-1H-isoquinolin-2-yl)-pyridin-4-ylmethanone