Problem statement: Answer the multiple-choice question.
Question: Which compound has a 7.744\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
[a] COC(=O)C1CCN(C(=O)COC(=O)[C@@H]2CC(O)CN2S(=O)(=O)c2ccc3c(c2)OCCO3)CC1
[b] Cc1ccc(C)c(NC(=O)CN(C)C(=O)Cn2c(=O)oc3ccccc32)c1
[c] COc1cc2c(cc1NC(=O)C(c1ccccc1)c1ccccc1)CCCC2
Answer: a. COC(=O)C1CCN(C(=O)COC(=O)[C@@H]2CC(O)CN2S(=O)(=O)c2ccc3c(c2)OCCO3)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1CCN(C(=O)COC(=O)[C@@H]2CC(O)CN2S(=O)(=O)c2ccc3c(c2)OCCO3)CC1
COC(=O)C1CCN(C(=O)COC(=O)[C@@H]2CC(O)CN2S(=O)(=O)c2ccc3c(c2)OCCO3)CC1
methyl 1-[2-[(2S)-1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-4-hydroxypyrrolidine-2-carbonyl]oxyacetyl]piperidine-4-carboxylate