Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -8.302\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CCC(C)C(NC(=O)C1CCC(C)CC1)C(=O)Nc1ccc(OC)cc1OC
b.) COc1ccc(CCNC(=O)C2CCC(=O)N(C3CCCCCC3)C2)cc1
c.) COc1ccccc1C(=O)NCc1ccccn1
d.) COC(=O)c1ccc(CN2CCCC(C(=O)c3cc(F)ccc3OC)C2)cc1
e.) Cc1cc(C)cc(N2C(=O)CN(Cc3ccccc3)C2=S)c1
Answer: d. COC(=O)c1ccc(CN2CCCC(C(=O)c3cc(F)ccc3OC)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(CN2CCCC(C(=O)c3cc(F)ccc3OC)C2)cc1
COC(=O)c1ccc(CN2CCCC(C(=O)c3cc(F)ccc3OC)C2)cc1
methyl 4-[[3-(5-fluoro-2-methoxybenzoyl)piperidin-1-yl]methyl]benzoate