Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -8.516\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
[a] COc1cc(OC)nc(NC(=O)CN2CCN(c3ccc(F)cc3)CC2)n1
[b] CC(C)(C)c1ccc(C(=O)NCC(=O)N2CCNC(=O)C2)cc1
[c] CC(=O)Nc1ccc(S(=O)(=O)NCCC(=O)OCC(=O)NNC(=O)c2ccccc2)cc1
[d] O=C(CNC(=O)c1cccs1)c1ccc(F)cc1
Answer: a. COc1cc(OC)nc(NC(=O)CN2CCN(c3ccc(F)cc3)CC2)n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(OC)nc(NC(=O)CN2CCN(c3ccc(F)cc3)CC2)n1
COc1cc(OC)nc(NC(=O)CN2CCN(c3ccc(F)cc3)CC2)n1
N-(4,6-dimethoxypyrimidin-2-yl)-2-[4-(4-fluorophenyl)piperazin-1-yl]acetamide