Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 0.746\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COC(=O)C1=C(C)N(C)C(=O)NC1c1cc(Cl)c(O)c(OC)c1
b) COc1ccc(-c2c(C)c3cc(O)ccc3oc2=O)cc1
c) O=C(NCc1ccc(F)cc1)c1cccc(NC2=NC3CS(=O)(=O)CC3S2)c1
d) CCOc1ncccc1C(=O)OCC(=O)c1cc(C)n(Cc2ccco2)c1C
e) Cc1cc(C(=O)CCC(=O)Nc2ncccc2O)c(C)s1
Answer: c. O=C(NCc1ccc(F)cc1)c1cccc(NC2=NC3CS(=O)(=O)CC3S2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCc1ccc(F)cc1)c1cccc(NC2=NC3CS(=O)(=O)CC3S2)c1
O=C(NCc1ccc(F)cc1)c1cccc(NC2=NC3CS(=O)(=O)CC3S2)c1
3-[(5,5-dioxo-3a,4,6,6a-tetrahydrothieno[3,4-d][1,3]thiazol-2-yl)amino]-N-[(4-fluorophenyl)methyl]benzamide