Problem statement: Answer the multiple-choice question.
Question: Which compound has a 6.244\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CC1CCCCN1C(=O)CCn1c(=S)oc2ccccc21
[b] CCOC(=O)C1CCCN(c2c(NCCc3ccc(S(N)(=O)=O)cc3)c(=O)c2=O)C1
[c] O=C(N/N=C/c1ccc2cccnc2c1)c1nc2ccccc2c(=O)[nH]1
[d] Cc1c(C(=O)NCCCN2CCOCC2)sc2nc(-c3ccccc3)cn12
[e] COc1ccc([C@H]2/C=C\CN(S(=O)(=O)/C=C/c3ccccc3)[C@@H](C)C(=O)N2Cc2ccc(F)cc2)cc1
Answer: b. CCOC(=O)C1CCCN(c2c(NCCc3ccc(S(N)(=O)=O)cc3)c(=O)c2=O)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1CCCN(c2c(NCCc3ccc(S(N)(=O)=O)cc3)c(=O)c2=O)C1
CCOC(=O)C1CCCN(c2c(NCCc3ccc(S(N)(=O)=O)cc3)c(=O)c2=O)C1
ethyl 1-[3,4-dioxo-2-[2-(4-sulfamoylphenyl)ethylamino]cyclobuten-1-yl]piperidine-3-carboxylate