Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -1.545\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCOC(=O)C1CN(S(=O)(=O)c2ccc(Cl)cc2)c2cc(S(=O)(=O)CC)ccc2O1
(b) COc1ccccc1N(C(=O)CCCl)C(C#N)c1ccccc1
(c) CC1(C)CC(=O)C2=C(C1)N1C(=C(C#N)C2c2cccc(Cl)c2)N=C(N)c2ccccc21
(d) CC(C)(C)NC(=O)NC(=O)CSc1n[nH]c(-c2ccccc2Br)n1
(e) CCOc1ccc(CCNC(=O)C2CCN(S(=O)(=O)c3ccc(C)cc3)CC2)cc1OCC
Answer: a. CCOC(=O)C1CN(S(=O)(=O)c2ccc(Cl)cc2)c2cc(S(=O)(=O)CC)ccc2O1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1CN(S(=O)(=O)c2ccc(Cl)cc2)c2cc(S(=O)(=O)CC)ccc2O1
CCOC(=O)C1CN(S(=O)(=O)c2ccc(Cl)cc2)c2cc(S(=O)(=O)CC)ccc2O1
ethyl 4-(4-chlorophenyl)sulfonyl-6-ethylsulfonyl-2,3-dihydro-1,4-benzoxazine-2-carboxylate