Problem statement: Answer the multiple-choice question.
Question: Which compound has a 5.576\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) O=C1CCc2cc(S(=O)(=O)NCCCC(=O)N3CCN(Cc4ccc5c(c4)OCO5)CC3)ccc2N1
b) O=C(CCc1ccc(O)c(O)c1)NNC(=S)NCCc1ccccc1
c) O=C(CCN1CCOCC1)NC1CCCN(Cc2ccccc2F)C1
d) CCn1cc(C(=O)N2CCN(c3ccc(OC)cc3)CC2)c2cc(OC)c(OC)cc2c1=O
Answer: d. CCn1cc(C(=O)N2CCN(c3ccc(OC)cc3)CC2)c2cc(OC)c(OC)cc2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCn1cc(C(=O)N2CCN(c3ccc(OC)cc3)CC2)c2cc(OC)c(OC)cc2c1=O
CCn1cc(C(=O)N2CCN(c3ccc(OC)cc3)CC2)c2cc(OC)c(OC)cc2c1=O
2-ethyl-6,7-dimethoxy-4-[4-(4-methoxyphenyl)piperazine-1-carbonyl]isoquinolin-1-one