Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 2.031\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COC(=O)c1ccccc1Oc1ccc(NC(=O)c2ccco2)cc1
b) Cc1cc(=O)n(CCO)c(O)c1C#N
c) N/C(=N\OC(=O)c1ccccc1Cl)c1cccc([N+](=O)[O-])c1
d) C[C@H]1O[C@@H](OC2CC[C@]3(C=O)[C@H]4CC[C@]5(C)[C@@H](C6=CC(=O)OC6)CC[C@]5(O)[C@@H]4CC[C@]3(O)C2)CC2OC(C)(C)OC21
e) C#CCNC(=O)C1=C[C@@H](c2ccc(C(F)(F)F)cc2)[C@H](CCCO)[C@@H](OCC)O1
Answer: e. C#CCNC(=O)C1=C[C@@H](c2ccc(C(F)(F)F)cc2)[C@H](CCCO)[C@@H](OCC)O1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C#CCNC(=O)C1=C[C@@H](c2ccc(C(F)(F)F)cc2)[C@H](CCCO)[C@@H](OCC)O1
C#CCNC(=O)C1=C[C@@H](c2ccc(C(F)(F)F)cc2)[C@H](CCCO)[C@@H](OCC)O1
(2S,3S,4R)-2-ethoxy-3-(3-hydroxypropyl)-N-prop-2-ynyl-4-[4-(trifluoromethyl)phenyl]-3,4-dihydro-2H-pyran-6-carboxamide