Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a 10.765\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COC1=CCC2([N+](=O)[O-])CN(C)CC1([N+](=O)[O-])C2
b. Cc1c(CC(=O)NCC(=O)NCC(=O)O)c(=O)oc2cc3c(cc12)CCC(C)(C)O3
c. CC(C)c1nc2c(s1)CCc1onc(-c3ccc(Cl)cc3)c1-2
d. COc1ccc(C2C(C(=O)N3CC(C)CC(C)C3)c3ccccc3C(=O)N2C)cc1
e. Cc1ccc(NC2=C/C(=N/S(=O)(=O)c3cccs3)c3ccccc3C2=O)cc1
Answer: d. COc1ccc(C2C(C(=O)N3CC(C)CC(C)C3)c3ccccc3C(=O)N2C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C2C(C(=O)N3CC(C)CC(C)C3)c3ccccc3C(=O)N2C)cc1
COc1ccc(C2C(C(=O)N3CC(C)CC(C)C3)c3ccccc3C(=O)N2C)cc1
4-(3,5-dimethylpiperidine-1-carbonyl)-3-(4-methoxyphenyl)-2-methyl-3,4-dihydroisoquinolin-1-one