Problem statement: Answer the multiple-choice question.
Question: Which compound has a 8.431\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CC(NC(=S)NCCCN1CCOCC1)C12CC3CC(CC(C3)C1)C2
b) CCCCn1c(=NC(=O)c2ccc3c(c2)OCO3)c(C#N)cc2c(=O)n3cccc(C)c3nc21
c) CC(=O)N1CCN(c2nc(CC(C)C)c3c(c2C#N)CCC3)CC1
d) COc1cccc(/C=N\NC(=O)c2ccc(C)nc2)c1
e) COc1ccc(Cl)cc1NC(=O)CN(C)CC(=O)NC(C)c1ccccc1
Answer: c. CC(=O)N1CCN(c2nc(CC(C)C)c3c(c2C#N)CCC3)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(=O)N1CCN(c2nc(CC(C)C)c3c(c2C#N)CCC3)CC1
CC(=O)N1CCN(c2nc(CC(C)C)c3c(c2C#N)CCC3)CC1
3-(4-acetylpiperazin-1-yl)-1-(2-methylpropyl)-6,7-dihydro-5H-cyclopenta[c]pyridine-4-carbonitrile