Problem statement: Answer the MCQ question.
Query: Which drug has a 1.270\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: O=C(O)C1=C[C@H](c2ccc(C(F)(F)F)cc2)C[C@H](OCCCCO)O1
b: Cc1ccc(C)c(OC(=O)c2ccncc2)c1
c: CC1CCN(CCc2nc3cc(NC(=O)C(C)C)ccc3n2C)CC1
d: CCOc1ccc(S(=O)(=O)N2CCC(C(=O)OCc3cccc(OC)c3OC)CC2)cc1
e: Cc1noc(C)c1CSc1nnc2scc(-c3ccccc3)n12
Answer: d. CCOc1ccc(S(=O)(=O)N2CCC(C(=O)OCc3cccc(OC)c3OC)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(S(=O)(=O)N2CCC(C(=O)OCc3cccc(OC)c3OC)CC2)cc1
CCOc1ccc(S(=O)(=O)N2CCC(C(=O)OCc3cccc(OC)c3OC)CC2)cc1
(2,3-dimethoxyphenyl)methyl 1-(4-ethoxyphenyl)sulfonylpiperidine-4-carboxylate