Problem statement: Answer the multiple-choice question.
Query: What is the human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM of a drug with the SMILES COC(=O)c1ccc2c(=O)n(CC3CCCO3)c(SCC(=O)NCCc3ccc(S(N)(=O)=O)cc3)nc2c1?
Constraint: You must return none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a 8.718
b -4.272
c 11.714
d 6.382
e 13.713
Answer: a. 8.718\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
COC(=O)c1ccc2c(=O)n(CC3CCCO3)c(SCC(=O)NCCc3ccc(S(N)(=O)=O)cc3)nc2c1
COC(=O)c1ccc2c(=O)n(CC3CCCO3)c(SCC(=O)NCCc3ccc(S(N)(=O)=O)cc3)nc2c1
methyl 4-oxo-3-(oxolan-2-ylmethyl)-2-[2-oxo-2-[2-(4-sulfamoylphenyl)ethylamino]ethyl]sulfanylquinazoline-7-carboxylate