Problem statement: Answer the multiple-choice question.
Query: Which compound has a 12.795\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C(O)C1=CC[C@@H](c2ccc(Cl)cc2)N(S(=O)(=O)c2ccc(Cl)cc2)[C@H]1c1ccc(F)cc1
b. CSc1cccc(NC(=S)N(Cc2ccc(C)cc2)Cc2ccccn2)c1
c. O=C(NCc1ccco1)Oc1ccccc1
d. CC(Cc1ccccc1)C(=O)Nc1ccc(Br)cc1
e. COc1cc(C(=O)Nc2ncccc2C)ccc1OCC(=O)N1CCOCC1
Answer: e. COc1cc(C(=O)Nc2ncccc2C)ccc1OCC(=O)N1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(C(=O)Nc2ncccc2C)ccc1OCC(=O)N1CCOCC1
COc1cc(C(=O)Nc2ncccc2C)ccc1OCC(=O)N1CCOCC1
3-methoxy-N-(3-methylpyridin-2-yl)-4-(2-morpholin-4-yl-2-oxoethoxy)benzamide