Task: Answer the multiple-choice question.
Question: Which drug has a 12.637\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. C/C(=N/NS(=O)(=O)c1ccccc1)c1ccc(NC(=O)C(F)(F)F)cc1
b. O=C(O)CN1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1
c. O=C(O)c1ccc(CSc2nnc(COc3ccccc3)o2)cc1
d. N#Cc1c(NC(=O)CN2CCN(C(=O)c3ccco3)CC2)sc2c1CCCCC2
e. CCOc1cc(-c2sc(Nc3ccccc3)n[n+]2C)ccc1OC.[Cl-]
Answer: b. O=C(O)CN1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(O)CN1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1
O=C(O)CN1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1
2-[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]-1-hydroxyethanone