Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -7.224\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CS(=O)(=O)N1CCN(c2ccc([N+](=O)[O-])cc2C(F)(F)F)CC1
b) CCNc1c(NC(=O)C2CCC(C)CC2)c(=O)oc2ccccc12
c) COc1ccc(-c2n[nH]c3c2CN(C(=O)c2ccc(F)cc2)CC3)cc1
d) CC(C)c1nc2sc3c(c2c(=O)n1N)CC(C)(C)OC3
e) Cc1ccc(-c2nnn(CC(=O)NCCC3=CCCCC3)n2)cc1
Answer: c. COc1ccc(-c2n[nH]c3c2CN(C(=O)c2ccc(F)cc2)CC3)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2n[nH]c3c2CN(C(=O)c2ccc(F)cc2)CC3)cc1
COc1ccc(-c2n[nH]c3c2CN(C(=O)c2ccc(F)cc2)CC3)cc1
(4-fluorophenyl)-[3-(4-methoxyphenyl)-1,4,6,7-tetrahydropyrazolo[4,3-c]pyridin-5-yl]methanone