Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 12.625\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO.Cl
(b) Cc1ccc(Cn2c(C(C)Nc3nc(-c4ccc(Cl)cc4)cs3)nc3cc(C(=O)NCCCO)ccc32)cc1
(c) COC(=O)C1=C(c2ccc(F)cc2OCc2ccccc2)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(C)cc1
(d) Cc1cc2ccc3ccccc3c2cc1CN(C)C.Cl
(e) Cc1c(C#N)c2ncnc(-c3ccccc3)c2n1-c1ccccc1
Answer: c. COC(=O)C1=C(c2ccc(F)cc2OCc2ccccc2)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccc(F)cc2OCc2ccccc2)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(C)cc1
COC(=O)C1=C(c2ccc(F)cc2OCc2ccccc2)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccc(C)cc1
methyl (1R,5S)-3-(4-fluoro-2-phenylmethoxyphenyl)-8-[(4-methylphenyl)methylcarbamoyl]-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate