Task: Answer the MCQ question.
Question: Which drug has a 4.943\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CN(Cc1ccccc1)C(=O)CN1C(=O)c2ccccc2S1(=O)=O
b. COC(=O)C1=C(c2ccc(F)cc2OCc2ccccc2)C[C@@H]2CC[C@H]1N2C(=O)NCc1ccccc1
c. COC(=O)C1CCN(C(c2cccs2)c2sc3nc(C)nn3c2O)CC1
d. COc1ccc(C(CNC(=O)c2ccc(S(=O)(=O)N3CCCC3)cc2)N2CCOCC2)cc1
e. FC(F)(F)c1nc(-c2ccncc2)ncc1-c1nnnn1-c1ccccc1
Answer: c. COC(=O)C1CCN(C(c2cccs2)c2sc3nc(C)nn3c2O)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1CCN(C(c2cccs2)c2sc3nc(C)nn3c2O)CC1
COC(=O)C1CCN(C(c2cccs2)c2sc3nc(C)nn3c2O)CC1
methyl 1-[(6-hydroxy-2-methyl-[1,3]thiazolo[3,2-b][1,2,4]triazol-5-yl)-thiophen-2-ylmethyl]piperidine-4-carboxylate