Problem statement: Answer the MCQ question.
Question: Which compound has a 6.618\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COCCCNC(=O)Cn1nnc(-c2ccccc2NC(=O)c2ccc(F)cc2)n1
b) CC(C)Cn1c(N)c(C(=O)COC(=O)/C=C/c2ccccc2)c(=O)n(C)c1=O
c) O=C(COC(=O)c1ccncc1)NCCCc1ccccc1
d) CSc1ccc2nnc(-c3cccc(F)c3)n2n1
e) CCN(CC)C(=O)CN1C(=O)C2(OCC(C)(c3ccccc3)CO2)c2ccccc21
Answer: b. CC(C)Cn1c(N)c(C(=O)COC(=O)/C=C/c2ccccc2)c(=O)n(C)c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)Cn1c(N)c(C(=O)COC(=O)/C=C/c2ccccc2)c(=O)n(C)c1=O
CC(C)Cn1c(N)c(C(=O)COC(=O)/C=C/c2ccccc2)c(=O)n(C)c1=O
[2-[4-amino-1-methyl-3-(2-methylpropyl)-2,6-dioxopyrimidin-5-yl]-2-oxoethyl] (E)-3-phenylprop-2-enoate