Problem statement: Answer the MCQ question.
Question: Which drug has a 4.814\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1ccc(Cc2nnc(NC(=O)c3cccs3)s2)cc1
b.) Cc1ncoc1C(=O)N1CCCC(CCC(=O)NCc2ccc(F)c(F)c2)C1
c.) COc1ccc(CCNC(=O)C(=O)NCC2OCCN2S(=O)(=O)c2ccc(F)cc2)cc1OC
d.) COc1ccc(S(=O)(=O)N[C@@H](Cc2ccc(Cl)cc2)C(=O)N2CC[C@@]3(O)CCCC[C@H]3C2)cc1
e.) CCC(C(=O)Nc1ccccc1N1CCCC1)c1ccccc1
Answer: b. Cc1ncoc1C(=O)N1CCCC(CCC(=O)NCc2ccc(F)c(F)c2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ncoc1C(=O)N1CCCC(CCC(=O)NCc2ccc(F)c(F)c2)C1
Cc1ncoc1C(=O)N1CCCC(CCC(=O)NCc2ccc(F)c(F)c2)C1
N-[(3,4-difluorophenyl)methyl]-3-[1-(4-methyl-1,3-oxazole-5-carbonyl)piperidin-3-yl]propanamide