Task: Answer the multiple choice question.
Question: Which compound has a -38.495\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COCCNC(=O)c1c[nH]c2ccc(S(=O)(=O)Nc3ccc(F)cc3F)cc2c1=O
b) CCOC(=O)c1cc(C(=O)Nc2ccc(S(=O)(=O)Nc3ccc(OC)cc3)cc2)nn1C
c) COc1ccc(Cl)cc1C(=O)NNC(=S)NC1CCCC1
d) COCc1ccc(C(=O)N(C)CC2CCCN(CCc3ccc(OC)cc3)C2)o1
e) CCOCCCN(C)C1CCN(C(=O)c2oc3ccccc3c2NC(=O)c2ccc(F)cc2)CC1
Answer: d. COCc1ccc(C(=O)N(C)CC2CCCN(CCc3ccc(OC)cc3)C2)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COCc1ccc(C(=O)N(C)CC2CCCN(CCc3ccc(OC)cc3)C2)o1
COCc1ccc(C(=O)N(C)CC2CCCN(CCc3ccc(OC)cc3)C2)o1
5-(methoxymethyl)-N-[[1-[2-(4-methoxyphenyl)ethyl]piperidin-3-yl]methyl]-N-methylfuran-2-carboxamide