Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 3.274\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(CNS(=O)(=O)c2cc(-c3cc(C)no3)ccc2C)cc1OC
(b) COc1ccc(NC(=O)CCC(=O)c2cccs2)cc1Cl
(c) COc1cnn(-c2cccc(Cl)c2)c(=O)c1Cl
(d) CC12CC3CC(C)(C1)CC(C(=O)NCc1ccncc1)(C3)C2
(e) COc1ccc(N(C)C(=O)c2oc(=O)c3ccccc3c2-c2ccc(C)cc2)c(OC)c1
Answer: e. COc1ccc(N(C)C(=O)c2oc(=O)c3ccccc3c2-c2ccc(C)cc2)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N(C)C(=O)c2oc(=O)c3ccccc3c2-c2ccc(C)cc2)c(OC)c1
COc1ccc(N(C)C(=O)c2oc(=O)c3ccccc3c2-c2ccc(C)cc2)c(OC)c1
N-(2,4-dimethoxyphenyl)-N-methyl-4-(4-methylphenyl)-1-oxoisochromene-3-carboxamide