Problem statement: Answer the multiple-choice question.
Query: Which compound has a 10.046\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a C/C(=N\NC(=O)c1ccccc1[N+](=O)[O-])c1ccc(Br)s1
b COc1ccccc1N1CCN(C(c2cccs2)C(C)NC(=O)c2cccs2)CC1
c COC(=O)C1C(c2ccc(OC)cc2)Nc2nnc(C(F)(F)F)n2C1(C)O
d COC(=O)CNC(=O)c1c(-c2ccccc2Cl)noc1C
e C=CCn1cc(C(=O)NCCOC)c(=O)c2cc(S(=O)(=O)N3CCCCCC3)ccc21
Answer: c. COC(=O)C1C(c2ccc(OC)cc2)Nc2nnc(C(F)(F)F)n2C1(C)O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1C(c2ccc(OC)cc2)Nc2nnc(C(F)(F)F)n2C1(C)O
COC(=O)C1C(c2ccc(OC)cc2)Nc2nnc(C(F)(F)F)n2C1(C)O
methyl 5-hydroxy-7-(4-methoxyphenyl)-5-methyl-3-(trifluoromethyl)-7,8-dihydro-6H-[1,2,4]triazolo[4,3-a]pyrimidine-6-carboxylate