Task: Answer the multiple-choice question.
Question: Which compound has a 2.749\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CC1CCC2(CC1)NC(=O)N(Cc1nc(-c3ccccc3)no1)C2=O
b. CC(C)COC(=O)Cn1cnc2ccc(Br)cc2c1=O
c. O=C(Cc1ccsc1)N1CCN(S(=O)(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1
d. CCOC(=O)C1C(=O)C(C(C)=O)C(=O)CC1CC(C)SCC
e. O=C1/C(=C/c2ccccc2)Nc2ccccc21
Answer: c. O=C(Cc1ccsc1)N1CCN(S(=O)(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Cc1ccsc1)N1CCN(S(=O)(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1
O=C(Cc1ccsc1)N1CCN(S(=O)(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1
1-[4-[3,5-bis(trifluoromethyl)phenyl]sulfonylpiperazin-1-yl]-2-thiophen-3-ylethanone