Problem statement: Answer the multiple choice question.
Question: Which compound has a -1.053\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCOC(=O)c1c(C)[nH]c(C(=O)N2CCCC(C(=O)c3cccc(OC)c3)C2)c1C
b. Cc1cc(C2C(C#N)=C(N)OC3=C2C(=O)CCC3)c(C)s1
c. CC(Oc1ccc(Cl)cc1)c1ccn[nH]1
d. CCCCN(C(=O)/C=C/c1ccc(OC)cc1)C1CCS(=O)(=O)C1
e. Cc1ccc(C(C)(O)CS(=O)(=O)Cc2ccccc2Cl)cc1
Answer: b. Cc1cc(C2C(C#N)=C(N)OC3=C2C(=O)CCC3)c(C)s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cc(C2C(C#N)=C(N)OC3=C2C(=O)CCC3)c(C)s1
Cc1cc(C2C(C#N)=C(N)OC3=C2C(=O)CCC3)c(C)s1
2-amino-4-(2,5-dimethylthiophen-3-yl)-5-oxo-4,6,7,8-tetrahydrochromene-3-carbonitrile