Problem statement: Answer the multiple choice question.
Question: Which drug has a -2.818\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1ccc(N(CC(=O)NCc2ccc3c(c2)OCO3)C(=O)c2csnn2)cc1
b. CCCN(Cc1nnc(-c2cccs2)o1)C(=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1C
c. O=C(Oc1ccc(C(=S)N2CCOCC2)cc1)c1cccc([N+](=O)[O-])c1
d. CCN1C(=O)c2ccccc2S(=O)(=O)c2ccc(C(=O)NCCCN(CC(C)C)CC(C)C)cc21
e. CC(C)(C)OC(=O)NCCCCCc1cn([C@@H](CO)C(=O)NCCCCCCCCCCC(=O)N2CCN(C(=O)OC(C)(C)C)CC2)nn1
Answer: b. CCCN(Cc1nnc(-c2cccs2)o1)C(=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCN(Cc1nnc(-c2cccs2)o1)C(=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1C
CCCN(Cc1nnc(-c2cccs2)o1)C(=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1C
2-methyl-5-morpholin-4-ylsulfonyl-N-propyl-N-[(5-thiophen-2-yl-1,3,4-oxadiazol-2-yl)methyl]benzamide