Problem statement: Answer the multiple choice question.
Question: Which compound has a -16.832\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: CCN1C(=NCc2ccc(OC)cc2)N[C@@H](CCc2ccccc2)[C@H](C(=O)NCc2ccc(OC)cc2)[C@H]1C
b: COc1cc2c(cc1OC)CN(C(=O)CNC(=O)c1ccc(OC(F)F)cc1)CC2
c: COc1cccc(NC(=O)CCN2C(=O)c3ccc([N+](=O)[O-])cc3C2=O)c1
d: Cc1ccc2cc(CCNC(=O)C3CCCCC3)c(=O)[nH]c2c1C
e: O=C(c1cc(=O)c2ccccc2o1)N(Cc1ccccc1)C1CCS(=O)(=O)C1
Answer: a. CCN1C(=NCc2ccc(OC)cc2)N[C@@H](CCc2ccccc2)[C@H](C(=O)NCc2ccc(OC)cc2)[C@H]1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN1C(=NCc2ccc(OC)cc2)N[C@@H](CCc2ccccc2)[C@H](C(=O)NCc2ccc(OC)cc2)[C@H]1C
CCN1C(=NCc2ccc(OC)cc2)N[C@@H](CCc2ccccc2)[C@H](C(=O)NCc2ccc(OC)cc2)[C@H]1C
(4S,5S,6R)-1-ethyl-N-[(4-methoxyphenyl)methyl]-2-[(4-methoxyphenyl)methylimino]-6-methyl-4-(2-phenylethyl)-1,3-diazinane-5-carboxamide