Problem statement: Answer the MCQ question.
Question: Which compound has a 12.102\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] CCOC(=O)C1CCCN(C(=O)c2sc3nc4n(c(=O)c3c2C)CCC4)C1
[b] CC(C)c1cccc(C(C)C)c1OC(=O)[C@H]1OC(c2ccc(Br)cc2)=C[C@@H]1c1ccc(Br)cc1
[c] S=c1[nH]nc(-c2cc(-c3ccco3)[nH]n2)n1-c1ccccc1
[d] CCN(CC)C(=O)Oc1ccnc2cc(Cl)ccc12
Answer: b. CC(C)c1cccc(C(C)C)c1OC(=O)[C@H]1OC(c2ccc(Br)cc2)=C[C@@H]1c1ccc(Br)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)c1cccc(C(C)C)c1OC(=O)[C@H]1OC(c2ccc(Br)cc2)=C[C@@H]1c1ccc(Br)cc1
CC(C)c1cccc(C(C)C)c1OC(=O)[C@H]1OC(c2ccc(Br)cc2)=C[C@@H]1c1ccc(Br)cc1
[2,6-di(propan-2-yl)phenyl] (2S,3R)-3,5-bis(4-bromophenyl)-2,3-dihydrofuran-2-carboxylate