Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 11.348\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CCOC(=O)c1ccc(NP(C)(=O)Oc2ccc(F)cc2)cc1
[b] O=C(c1ccc(Cl)c(S(=O)(=O)N2CCCC2)c1)N1CCN(c2ccccc2)CC1
[c] CCOC(=O)c1ccc(N=CC2=C(O)CC(C)(C)CC2=O)cc1
[d] CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(CCC(=O)N2CCCCC2)c(=O)c2sccc21
[e] CS(=O)(=O)Nc1ccccc1C(=O)NCCSc1ccc(Cl)cc1
Answer: d. CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(CCC(=O)N2CCCCC2)c(=O)c2sccc21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(CCC(=O)N2CCCCC2)c(=O)c2sccc21
CCN(Cc1ccccc1)C(=O)Cn1c(=O)n(CCC(=O)N2CCCCC2)c(=O)c2sccc21
N-benzyl-2-[2,4-dioxo-3-(3-oxo-3-piperidin-1-ylpropyl)thieno[3,2-d]pyrimidin-1-yl]-N-ethylacetamide