Problem statement: Answer the multiple-choice question.
Question: Which drug has a 14.107\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCC(=O)Nc1cccc(C2=NOC3(C2)C[C@H](C(N)=O)N(C(=O)Cc2ccc([N+](=O)[O-])cc2)C3)c1
b) Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)N1CCOCC1
c) O=C(c1ccc(C(F)(F)F)cc1)C1CCCN(C(=O)CCc2cnccn2)C1
d) COc1cc(S(=O)(=O)N2CCN(C)CC2)c(OC)cc1Cl
e) O=C(COC(=O)c1ccc(Br)o1)Nc1ncc(Cl)cc1Cl
Answer: c. O=C(c1ccc(C(F)(F)F)cc1)C1CCCN(C(=O)CCc2cnccn2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccc(C(F)(F)F)cc1)C1CCCN(C(=O)CCc2cnccn2)C1
O=C(c1ccc(C(F)(F)F)cc1)C1CCCN(C(=O)CCc2cnccn2)C1
3-pyrazin-2-yl-1-[3-[4-(trifluoromethyl)benzoyl]piperidin-1-yl]propan-1-one