Problem statement: Answer the multiple-choice question.
Question: Which drug has a 3.653\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C(COC(=O)C1CC(O)CN1S(=O)(=O)c1ccc(Cl)cc1)c1ccccc1
b.) O=C(CNC(=O)c1ccc(Cl)cc1Cl)OCC(=O)N1CCCC1=O
c.) COc1ccc(C(=O)O/N=C(\N)c2ccc(Br)cc2)cc1
d.) COCc1cc(C)nc(SCc2ccc(F)cc2)c1C#N
e.) CC1CCCN(S(=O)(=O)c2ccc(C(=O)Nc3sc4c(c3C(N)=O)CCN(C)C4)cc2)C1
Answer: b. O=C(CNC(=O)c1ccc(Cl)cc1Cl)OCC(=O)N1CCCC1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CNC(=O)c1ccc(Cl)cc1Cl)OCC(=O)N1CCCC1=O
O=C(CNC(=O)c1ccc(Cl)cc1Cl)OCC(=O)N1CCCC1=O
[2-oxo-2-(2-oxopyrrolidin-1-yl)ethyl] 2-[(2,4-dichlorobenzoyl)amino]acetate