Problem statement: Answer the MCQ question.
Question: Which compound has a -18.808\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] Cc1cccc(NC(=O)c2ccc(F)c(S(=O)(=O)N3CCC4(CC3)OCCO4)c2)c1
[b] CN(CCOc1ccc(Br)cc1)CC(=O)Nc1cccc(S(=O)(=O)NC2=NCCC2)c1
[c] Cc1cc(-c2cc(C(=O)Nc3ccccc3)on2)nc(NCC2CC2)n1
[d] COc1ccc(CC(NC(C)=O)C(=O)NC2CCN(c3ncccc3[N+](=O)[O-])CC2)cc1
[e] CCc1ccc2c(CN(C)Cc3ccc(OC(F)F)c(OC)c3)cc(=O)oc2c1
Answer: e. CCc1ccc2c(CN(C)Cc3ccc(OC(F)F)c(OC)c3)cc(=O)oc2c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCc1ccc2c(CN(C)Cc3ccc(OC(F)F)c(OC)c3)cc(=O)oc2c1
CCc1ccc2c(CN(C)Cc3ccc(OC(F)F)c(OC)c3)cc(=O)oc2c1
4-[[[4-(difluoromethoxy)-3-methoxyphenyl]methyl-methylamino]methyl]-7-ethylchromen-2-one