Problem statement: Answer the multiple-choice question.
Question: Which drug has a -12.101\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: COCCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1cccc(S(=O)(=O)N2CCCC2)c1
b: Cc1onc(-c2c(F)cccc2Cl)c1C(=O)NNC(=O)C1CCN(Cc2cccc(F)c2)CC1
c: CC(=O)N1C(Nc2ccc(Cl)cc2)CCN1c1ccccc1
d: O=C1C2CCCN2C(=O)N1CCCCN1CCN(CCO)CC1
Answer: d. O=C1C2CCCN2C(=O)N1CCCCN1CCN(CCO)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1C2CCCN2C(=O)N1CCCCN1CCN(CCO)CC1
O=C1C2CCCN2C(=O)N1CCCCN1CCN(CCO)CC1
2-[4-[4-(2-hydroxyethyl)piperazin-1-yl]butyl]-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazole-1,3-dione