Problem statement: Answer the multiple-choice question.
Query: Which compound has a -21.441\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] O=C1Nc2ccc(F)cc2C12Nc1ccccc1-c1nnc(SCc3ccccc3Cl)nc1O2
[b] Cc1ccc(-n2nc(C(=O)O)cc2-c2ccccc2Cl)cc1
[c] C/C(=N\N=C1\NC(=O)C(Cc2ccccc2)S1)c1ccccc1
[d] O=C1CC2(CCN(C(=O)COc3ccccc3)CC2)Oc2ccccc21
[e] Clc1ccc(OCc2nc(-c3ccc(Br)o3)no2)cc1
Answer: d. O=C1CC2(CCN(C(=O)COc3ccccc3)CC2)Oc2ccccc21
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C1CC2(CCN(C(=O)COc3ccccc3)CC2)Oc2ccccc21
O=C1CC2(CCN(C(=O)COc3ccccc3)CC2)Oc2ccccc21
1'-(2-phenoxyacetyl)spiro[3H-chromene-2,4'-piperidine]-4-one