Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -9.181\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C(c1cc(-c2ccncc2)nc2ccc(Br)cc12)N1CCN(c2ccccn2)CC1
b) CN(CC(=O)Nc1cccc(F)c1)C(=O)/C=C/c1cn(Cc2ccccc2)nc1-c1cccnc1
c) CC(=O)c1ccc(N2CCN(C(=O)c3ccco3)CC2)c(F)c1
d) C=C(C)CNC(=S)N/N=C(\C)c1ccc(OC)cc1
e) CCCCc1ccc(NC(=O)N[C@@H](C)C(=O)O)cc1
Answer: a. O=C(c1cc(-c2ccncc2)nc2ccc(Br)cc12)N1CCN(c2ccccn2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1cc(-c2ccncc2)nc2ccc(Br)cc12)N1CCN(c2ccccn2)CC1
O=C(c1cc(-c2ccncc2)nc2ccc(Br)cc12)N1CCN(c2ccccn2)CC1
(6-bromo-2-pyridin-4-ylquinolin-4-yl)-(4-pyridin-2-ylpiperazin-1-yl)methanone