Problem statement: Answer the MCQ question.
Query: Which drug has a -5.458\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)Cc1cccs1
b) CC1CCN(C(=O)CN2C(=O)NC3(CCC(C)CC3)C2=O)CC1
c) CC1(C)CC(NC(=O)CCc2ccccc2)CC(C)(C)N1.Cl
d) COc1ccccc1NS(=O)(=O)c1ccc2c(c1)NC(=O)C(C)S2
e) Cc1ccc(N2C(=O)NC(NC(=O)C(C)(C)C)(C(F)(F)F)C2=O)cc1C
Answer: b. CC1CCN(C(=O)CN2C(=O)NC3(CCC(C)CC3)C2=O)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1CCN(C(=O)CN2C(=O)NC3(CCC(C)CC3)C2=O)CC1
CC1CCN(C(=O)CN2C(=O)NC3(CCC(C)CC3)C2=O)CC1
8-methyl-3-[2-(4-methylpiperidin-1-yl)-2-oxoethyl]-1,3-diazaspiro[4.5]decane-2,4-dione