Problem statement: Answer the multiple-choice question.
Query: Which compound has a 2.244\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CC(C)(C)c1nc(SCC(=O)NCc2cccs2)c2ccccc2n1
b) COc1ccc(/C=C/C(=O)O)cc1S(=O)(=O)N1CCc2ccccc21
c) Cc1ccccc1CNC(=O)CCn1nc(C)c2c(C)n(-c3ccccc3)nc2c1=O
d) CCOCCCNC(=O)c1ccc2c(c1)N(Cc1ccccc1)C(=O)CS2=O
e) O=C(NCc1ccccc1)C1=C[C@@H](c2ccc3c(c2)OCO3)C[C@@H](OCCCCO)O1
Answer: c. Cc1ccccc1CNC(=O)CCn1nc(C)c2c(C)n(-c3ccccc3)nc2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccccc1CNC(=O)CCn1nc(C)c2c(C)n(-c3ccccc3)nc2c1=O
Cc1ccccc1CNC(=O)CCn1nc(C)c2c(C)n(-c3ccccc3)nc2c1=O
3-(3,4-dimethyl-7-oxo-2-phenylpyrazolo[3,4-d]pyridazin-6-yl)-N-[(2-methylphenyl)methyl]propanamide