Problem statement: Answer the MCQ question.
Question: Which drug exhibits a -6.448\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccc(-c2nn(CCC#N)cc2C(=O)Nc2ccccc2)cc1OC
b) COc1ccccc1NS(=O)(=O)c1cccc(C(=O)NCC(C)(C)N2CCOCC2)c1
c) CC(=O)OC[C@]1(OC(C)=O)C[C@@]23CC[C@H]4[C@@](C)(CCC[C@@]4(C)C(=O)O)[C@@H]2CC[C@@H]1C3
d) O=C1CC2(CCN(C(=O)COc3ccc(F)cc3)CC2)Oc2ccccc21
e) CC(C)c1ccc(/C=N\NC(=O)c2ccc(Cn3cccn3)o2)cc1
Answer: a. COc1ccc(-c2nn(CCC#N)cc2C(=O)Nc2ccccc2)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2nn(CCC#N)cc2C(=O)Nc2ccccc2)cc1OC
COc1ccc(-c2nn(CCC#N)cc2C(=O)Nc2ccccc2)cc1OC
1-(2-cyanoethyl)-3-(3,4-dimethoxyphenyl)-N-phenylpyrazole-4-carboxamide