Problem statement: Answer the multiple choice question.
Query: Which compound exhibits a 10.817\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. O=C(Nc1cccnc1)c1ccc(N2CCOCC2)c([N+](=O)[O-])c1
b. Cc1ccc(/C=N/N=C2/NC(=O)C(CC(=O)N3CCOCC3)S2)cc1
c. Cc1ccc(-c2nn(CC(=O)N(C)C)c(=O)c3ccccc23)cc1S(=O)(=O)N(C)C
d. COc1ccc(C(=O)CN(C(=O)c2ccc(Cl)cc2)N2C(=O)C3CCCCC3C2=O)cc1
e. Cn1c(CNC(=O)CNC(=O)c2ccccc2F)cc(=O)n(C)c1=O
Answer: d. COc1ccc(C(=O)CN(C(=O)c2ccc(Cl)cc2)N2C(=O)C3CCCCC3C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)CN(C(=O)c2ccc(Cl)cc2)N2C(=O)C3CCCCC3C2=O)cc1
COc1ccc(C(=O)CN(C(=O)c2ccc(Cl)cc2)N2C(=O)C3CCCCC3C2=O)cc1
4-chloro-N-(1,3-dioxo-3a,4,5,6,7,7a-hexahydroisoindol-2-yl)-N-[2-(4-methoxyphenyl)-2-oxoethyl]benzamide