Problem statement: Answer the MCQ question.
Query: Which drug has a -10.886\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a) O=C(c1ccoc1)N1CCCC(N2CCN(c3cccc(C(F)(F)F)c3)CC2)C1
b) CC(C)c1ccc(/C=C(\NC(=O)c2ccccc2)C(=O)NCCCN2CCOCC2)cc1
c) CCCCNC(=O)CCn1c(=S)[nH]c2cc3c(cc2c1=O)OCO3
d) Cc1nc(C#N)c(NCc2ccc3c(c2)OCO3)o1
Answer: a. O=C(c1ccoc1)N1CCCC(N2CCN(c3cccc(C(F)(F)F)c3)CC2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccoc1)N1CCCC(N2CCN(c3cccc(C(F)(F)F)c3)CC2)C1
O=C(c1ccoc1)N1CCCC(N2CCN(c3cccc(C(F)(F)F)c3)CC2)C1
furan-3-yl-[3-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]piperidin-1-yl]methanone