Problem statement: Answer the MCQ question.
Question: Which drug has a 5.430\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Nc1cccc(NC(=O)CN2CCOCC2)c1
b. CCOc1ccc(C(C(=O)NCC2CCCO2)N(Cc2cccs2)C(=O)c2snc(C(N)=O)c2N)cc1
c. CCn1c(/C=C/c2ccccc2)nc2ccccc2c1=O
d. O=C(C1=NN[C@@H]2C(=O)N(c3ccccc3C(F)(F)F)C(=O)[C@H]12)c1cnccn1
e. Cc1nn(C(C)C(=O)NC(C)CCc2ccccc2)c(=O)c2cc3occc3n12
Answer: d. O=C(C1=NN[C@@H]2C(=O)N(c3ccccc3C(F)(F)F)C(=O)[C@H]12)c1cnccn1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(C1=NN[C@@H]2C(=O)N(c3ccccc3C(F)(F)F)C(=O)[C@H]12)c1cnccn1
O=C(C1=NN[C@@H]2C(=O)N(c3ccccc3C(F)(F)F)C(=O)[C@H]12)c1cnccn1
(3aS,6aS)-3-(pyrazine-2-carbonyl)-5-[2-(trifluoromethyl)phenyl]-3a,6a-dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione