Problem statement: Answer the multiple choice question.
Question: Which drug has a 8.125\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: O=C(O)C(=O)O.O=S(=O)(c1ccc(Cl)cc1)N1CCN(Cc2ccncc2)CC1
b: CC(C)C(NC(=O)c1ccccc1)C(=O)NCc1ccccn1
c: Cc1cc(C)cc(NC(=O)CN2CCN(CCN=CC3=C(O)CC(c4ccc(Cl)cc4)CC3=O)CC2)c1
d: COc1cc(/C=C/C(=O)OCC(=O)c2ccc3c(c2)NC(=O)CO3)ccc1OC(F)F
Answer: d. COc1cc(/C=C/C(=O)OCC(=O)c2ccc3c(c2)NC(=O)CO3)ccc1OC(F)F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(/C=C/C(=O)OCC(=O)c2ccc3c(c2)NC(=O)CO3)ccc1OC(F)F
COc1cc(/C=C/C(=O)OCC(=O)c2ccc3c(c2)NC(=O)CO3)ccc1OC(F)F
[2-oxo-2-(3-oxo-4H-1,4-benzoxazin-6-yl)ethyl] (E)-3-[4-(difluoromethoxy)-3-methoxyphenyl]prop-2-enoate