Problem statement: Answer the multiple-choice question.
Question: Which drug has a 3.323\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a S=c1[nH]nc(C2CCCCC2)n1/N=C/c1ccc(Br)cc1
b Br.COc1ccc(-c2nc(C)sc2C)cc1
c Cc1ccc(/C=C(\C#N)C(=O)c2ccccc2)s1
d Cc1ccc(C(=O)NNC(=O)C2CCN(Cc3ccccc3)CC2)cc1
e COc1ccc2c(c1)C1NC(=S)N[C@@](C)(O2)C1C(=O)Nc1ccccc1
Answer: e. COc1ccc2c(c1)C1NC(=S)N[C@@](C)(O2)C1C(=O)Nc1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2c(c1)C1NC(=S)N[C@@](C)(O2)C1C(=O)Nc1ccccc1
COc1ccc2c(c1)C1NC(=S)N[C@@](C)(O2)C1C(=O)Nc1ccccc1
(9S)-4-methoxy-9-methyl-N-phenyl-11-sulfanylidene-8-oxa-10,12-diazatricyclo[7.3.1.02,7]trideca-2(7),3,5-triene-13-carboxamide