Problem statement: Answer the multiple-choice question.
Query: Which drug has a -2.296\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1ccc(/C=C/C(=O)OCC(=O)c2ccc3c(c2)NC(=O)CO3)cc1
b.) CC(C)CNS(=O)(=O)c1ccc(CCC(=O)NCc2ccc(Cl)cc2)cc1
c.) C/C(=N/NC(=O)CN1CCN(Cc2ccccc2Cl)CC1)c1ccco1
d.) CCOC(=O)C(NC(=O)CC)(Nc1nc2c(s1)CCCC2)C(F)(F)F
e.) CCN(CC)c1ccc(C=NCCNS(=O)(=O)c2ccc(C)cc2)cc1
Answer: d. CCOC(=O)C(NC(=O)CC)(Nc1nc2c(s1)CCCC2)C(F)(F)F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C(NC(=O)CC)(Nc1nc2c(s1)CCCC2)C(F)(F)F
CCOC(=O)C(NC(=O)CC)(Nc1nc2c(s1)CCCC2)C(F)(F)F
ethyl 3,3,3-trifluoro-2-(propanoylamino)-2-(4,5,6,7-tetrahydro-1,3-benzothiazol-2-ylamino)propanoate