Problem statement: Answer the multiple-choice question.
Question: Which compound has a -10.581\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: COc1cccc(C(CC(=O)Nc2cccc3ccccc23)NC(=O)c2ccccc2)c1
b: S=C(Nc1ccc2c(c1)OCO2)N1CCCC1
c: CCNC(=O)CC1C(=O)N(CC)C(=S)N1NC(=O)c1ccc(Cl)cc1
d: N#CC1=C(N)SC(N)=C(C#N)C1C1CC=CCC1
e: CCOc1c(C)cnc2c1c(=O)n(Cc1cccc(Cl)c1)c(=O)n2C
Answer: e. CCOc1c(C)cnc2c1c(=O)n(Cc1cccc(Cl)c1)c(=O)n2C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1c(C)cnc2c1c(=O)n(Cc1cccc(Cl)c1)c(=O)n2C
CCOc1c(C)cnc2c1c(=O)n(Cc1cccc(Cl)c1)c(=O)n2C
3-[(3-chlorophenyl)methyl]-5-ethoxy-1,6-dimethylpyrido[2,3-d]pyrimidine-2,4-dione