Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a -10.491\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccccc1C(=O)N1CCN(CCNC(=O)C(=O)Nc2ccc(Br)c(C)c2)CC1
[b] O=C(Nc1ccc(Br)cc1Br)C1CC(=O)N(Cc2ccccc2)C1
[c] O=C(O)c1cccc(Sc2ccc(Br)cc2C(=O)O)c1
[d] Clc1ccc(OCCn2ccnc2)c(Br)c1
[e] CC1(C)CC(=O)C2=C(C1)Nc1ccccc1N(C(=O)C1CC1)C2c1ccco1
Answer: a. COc1ccccc1C(=O)N1CCN(CCNC(=O)C(=O)Nc2ccc(Br)c(C)c2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1C(=O)N1CCN(CCNC(=O)C(=O)Nc2ccc(Br)c(C)c2)CC1
COc1ccccc1C(=O)N1CCN(CCNC(=O)C(=O)Nc2ccc(Br)c(C)c2)CC1
N'-(4-bromo-3-methylphenyl)-N-[2-[4-(2-methoxybenzoyl)piperazin-1-yl]ethyl]oxamide