Problem statement: Answer the multiple-choice question.
Question: Which compound has a 16.039\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a.) N#Cc1ccc(NC(=O)COC(=O)c2ccc(F)c(S(=O)(=O)N3CCOCC3)c2)cc1
b.) CC(C)c1cc(C(C)C)c(S(=O)(=O)N2c3ccccc3[C@@]3(Br)C[C@H]4C(=O)N[C@@H](Cc5ccccc5)C(=O)N4[C@@H]23)c(C(C)C)c1
c.) O=C(Nc1cc(S(=O)(=O)Nc2ccc(Cl)cc2)ccc1N1CCCCC1)c1ccc(F)cc1
d.) COC(=O)Nc1c(-c2ccccc2)nc2ccc(Cl)cn12
Answer: b. CC(C)c1cc(C(C)C)c(S(=O)(=O)N2c3ccccc3[C@@]3(Br)C[C@H]4C(=O)N[C@@H](Cc5ccccc5)C(=O)N4[C@@H]23)c(C(C)C)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)c1cc(C(C)C)c(S(=O)(=O)N2c3ccccc3[C@@]3(Br)C[C@H]4C(=O)N[C@@H](Cc5ccccc5)C(=O)N4[C@@H]23)c(C(C)C)c1
CC(C)c1cc(C(C)C)c(S(=O)(=O)N2c3ccccc3[C@@]3(Br)C[C@H]4C(=O)N[C@@H](Cc5ccccc5)C(=O)N4[C@@H]23)c(C(C)C)c1
(1S,4S,7S,9S)-4-benzyl-9-bromo-16-[2,4,6-tri(propan-2-yl)phenyl]sulfonyl-2,5,16-triazatetracyclo[7.7.0.02,7.010,15]hexadeca-10,12,14-triene-3,6-dione