Problem statement: Answer the multiple choice question.
Query: Which compound has a -10.292\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a COc1ccc(CCN2CC(C(=O)NCCc3ccccc3C(F)(F)F)CCC2=O)cc1
b O=C1OCCC1Sc1nc2ccccc2c(=O)n1Cc1ccc(F)cc1
c CC(=O)C1=C(C)Nc2ncnn2C1c1cccc(OCc2ccccc2)c1
d Cc1cc(C)c(S(=O)(=O)N2CCCCC2CCNC(=O)C(=O)NCC2CCCO2)c(C)c1
Answer: a. COc1ccc(CCN2CC(C(=O)NCCc3ccccc3C(F)(F)F)CCC2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CCN2CC(C(=O)NCCc3ccccc3C(F)(F)F)CCC2=O)cc1
COc1ccc(CCN2CC(C(=O)NCCc3ccccc3C(F)(F)F)CCC2=O)cc1
1-[2-(4-methoxyphenyl)ethyl]-6-oxo-N-[2-[2-(trifluoromethyl)phenyl]ethyl]piperidine-3-carboxamide