Problem statement: Answer the MCQ question.
Question: Which compound has a 18.005\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] O=[n+]1c2c(n([O-])c3cc(F)c(N4CCCC4)cc31)CCCC2
[b] CCCCn1c(N)c(N(CC(C)C)C(=O)c2cccc(S(=O)(=O)N3CC(C)OC(C)C3)c2)c(=O)[nH]c1=O
[c] CC(=O)n1cc([C@@H]2C=C(C(=O)NCc3ccccc3)O[C@H](OCc3ccc(CO)cc3)C2)c2ccccc21
[d] CCOc1cccc2sc(=NC(=O)c3ccco3)n(CC(=O)OC)c12
[e] Cc1cccc(Nc2nnc(C)c(=O)n2N)c1
Answer: b. CCCCn1c(N)c(N(CC(C)C)C(=O)c2cccc(S(=O)(=O)N3CC(C)OC(C)C3)c2)c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCn1c(N)c(N(CC(C)C)C(=O)c2cccc(S(=O)(=O)N3CC(C)OC(C)C3)c2)c(=O)[nH]c1=O
CCCCn1c(N)c(N(CC(C)C)C(=O)c2cccc(S(=O)(=O)N3CC(C)OC(C)C3)c2)c(=O)[nH]c1=O
N-(6-amino-1-butyl-2,4-dioxopyrimidin-5-yl)-3-(2,6-dimethylmorpholin-4-yl)sulfonyl-N-(2-methylpropyl)benzamide