Problem statement: Answer the multiple-choice question.
Question: Which drug has a 8.218\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CCN1C(=O)CC(c2cccnc2)=Nc2ccccc21
b O=C(O)CCCCCNS(=O)(=O)c1ccc2c(c1)OCCO2
c O=C(CCCOc1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1
d COc1cc2c(cc1OC)C(c1cc3cc4c(cc3[nH]c1=O)OCO4)N(C(=O)C1CC1)CC2
e CCc1nc2ccccc2n1CC1CC1(Cl)Cl
Answer: c. O=C(CCCOc1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCCOc1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1
O=C(CCCOc1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1
1-[4-(benzenesulfonyl)piperazin-1-yl]-4-phenoxybutan-1-one