Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -2.728\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) Cc1sc(NC(=O)CS(=O)(=O)c2ccccc2)c(C(N)=O)c1C
b) Cc1cc(O)c(NC(=O)c2ccc(Br)o2)cc1C
c) Cc1cn([C@@H](CCCCN)C(=O)NCCCCCCCCCCC(=O)N2CCNCC2)nn1
d) CCC(Sc1nc2cc(OC)c(OC)cc2c(=O)n1Cc1ccc(OC)cc1)C(=O)NCCOC
e) COc1ccc(/C=C(/NC(=O)c2ccco2)C(=O)NCc2ccco2)cc1OC
Answer: a. Cc1sc(NC(=O)CS(=O)(=O)c2ccccc2)c(C(N)=O)c1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1sc(NC(=O)CS(=O)(=O)c2ccccc2)c(C(N)=O)c1C
Cc1sc(NC(=O)CS(=O)(=O)c2ccccc2)c(C(N)=O)c1C
2-[[2-(benzenesulfonyl)acetyl]amino]-4,5-dimethylthiophene-3-carboxamide