Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 12.402\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1ccc(C[C@@H]2CN3C(=NC[C@@H]3C)N2C[C@H](C)NC(=O)c2ccc(C)c(Br)c2)cc1
b.) Cc1ccc(-n2cccn2)c(CN2CCCC(C(=O)c3sccc3C)C2)c1
c.) C=CCN1C(=O)c2ccc(C(=O)N3CCN(S(=O)(=O)c4cccc(Cl)c4)CC3)cc2C1=O
d.) CCN(CC(=O)Nc1ccc(NC(C)=O)cc1)CC(=O)Nc1ccc(Cl)c(Cl)c1.O=C(O)C(=O)O
e.) O=C(CSc1ccccc1)Nc1ccc2c(c1)OCCO2
Answer: c. C=CCN1C(=O)c2ccc(C(=O)N3CCN(S(=O)(=O)c4cccc(Cl)c4)CC3)cc2C1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C=CCN1C(=O)c2ccc(C(=O)N3CCN(S(=O)(=O)c4cccc(Cl)c4)CC3)cc2C1=O
C=CCN1C(=O)c2ccc(C(=O)N3CCN(S(=O)(=O)c4cccc(Cl)c4)CC3)cc2C1=O
5-[4-(3-chlorophenyl)sulfonylpiperazine-1-carbonyl]-2-prop-2-enylisoindole-1,3-dione