Problem statement: Answer the multiple-choice question.
Query: Which compound has a 10.784\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccccc1N1CCN(C(=O)C(C)CS(=O)(=O)c2ccc3c(c2)NC(=O)CS3)CC1
[b] Cc1ccc(-c2ocnc2C(=O)N2CCN(C(=O)c3cccs3)CC2)cc1
[c] Cc1ccc(S(=O)(=O)N(C)c2ccc(C(=O)O)cc2)cc1
[d] CCOC(=O)C(C)Sc1ncnc2nc[nH]c12
[e] COC(=O)[C@H](Cc1ccccc1)NC(=O)NCc1ccc(S(N)(=O)=O)cc1
Answer: a. COc1ccccc1N1CCN(C(=O)C(C)CS(=O)(=O)c2ccc3c(c2)NC(=O)CS3)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1N1CCN(C(=O)C(C)CS(=O)(=O)c2ccc3c(c2)NC(=O)CS3)CC1
COc1ccccc1N1CCN(C(=O)C(C)CS(=O)(=O)c2ccc3c(c2)NC(=O)CS3)CC1
6-[3-[4-(2-methoxyphenyl)piperazin-1-yl]-2-methyl-3-oxopropyl]sulfonyl-4H-1,4-benzothiazin-3-one