Problem statement: Answer the multiple choice question.
Question: Which compound has a -36.473\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccccc1C(=O)Nc1ccnn1C1CCN(Cc2cc(C)c(C)cc2C)CC1
[b] COc1cc(C(=O)COC(=O)Cc2cnc3sccn23)cc(OC)c1OC
[c] CCCC(C)NC(=O)c1ccc(OCc2ccc(Cl)cc2)c(OC)c1
[d] CC1CCCCN1C(=O)Cn1nnc(-c2cccnc2)n1
[e] Cc1cc(NC(=O)CN2C(=O)/C(=C/c3ccccc3F)SC2=S)no1
Answer: a. COc1ccccc1C(=O)Nc1ccnn1C1CCN(Cc2cc(C)c(C)cc2C)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1C(=O)Nc1ccnn1C1CCN(Cc2cc(C)c(C)cc2C)CC1
COc1ccccc1C(=O)Nc1ccnn1C1CCN(Cc2cc(C)c(C)cc2C)CC1
2-methoxy-N-[2-[1-[(2,4,5-trimethylphenyl)methyl]piperidin-4-yl]pyrazol-3-yl]benzamide