Problem statement: Answer the multiple-choice question.
Question: Which compound has a 5.590\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCN(CCCNC(=O)c1nn(C)c2c1CS(=O)(=O)c1ccccc1-2)Cc1ccccc1
(b) CCOC(=O)[C@H]1[C@H]2COc3cc(OC)ccc3[C@@H]2N2C(=O)CN(Cc3ccco3)C(=O)[C@@]12C
(c) C/C(=N\NC(=O)Cc1cccn1C)c1cccs1
(d) Cc1ccc(CNC(=O)[C@H](C)N2C(=O)N3CCc4c([nH]c5ccccc45)[C@@]3(C)C2=O)cc1
(e) CN1CCN(S(=O)(=O)c2ccc3c(c2)CC(=O)N3C)CC1
Answer: e. CN1CCN(S(=O)(=O)c2ccc3c(c2)CC(=O)N3C)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1CCN(S(=O)(=O)c2ccc3c(c2)CC(=O)N3C)CC1
CN1CCN(S(=O)(=O)c2ccc3c(c2)CC(=O)N3C)CC1
1-methyl-5-(4-methylpiperazin-1-yl)sulfonyl-3H-indol-2-one