Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -0.715\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a CCOc1ccc2oc(-c3ccccc3)c(C(=O)O)c2c1
b O=C1OCC2=C1C(c1ccccc1)CC(=O)N2c1ccccc1
c CC1=C(C(=O)OCc2ccccc2)C(c2ccccc2Cl)NC(=O)N1CCCCCC(=O)O
d COc1ccc(-c2cccc(C(=O)Nc3ccc(OC)c(OC)c3)c2)cc1
e COC(=O)c1[nH]c2cc(C)ccc2c1NC(=O)CN1CCN(c2ccccc2OC)CC1
Answer: e. COC(=O)c1[nH]c2cc(C)ccc2c1NC(=O)CN1CCN(c2ccccc2OC)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1[nH]c2cc(C)ccc2c1NC(=O)CN1CCN(c2ccccc2OC)CC1
COC(=O)c1[nH]c2cc(C)ccc2c1NC(=O)CN1CCN(c2ccccc2OC)CC1
methyl 3-[[2-[4-(2-methoxyphenyl)piperazin-1-yl]acetyl]amino]-6-methyl-1H-indole-2-carboxylate