Problem statement: Answer the MCQ question.
Question: Which compound exhibits a -4.158\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C(NCc1ccc(F)cc1)C(=O)Nc1nc(C23CC4CC(CC(C4)C2)C3)cs1
b) N#Cc1ccc(C(=O)OCC(=O)Nc2cccc(S(=O)(=O)N3CCCCC3)c2)cc1
c) CCOC(=O)C1=C(COC(=O)Cc2c(F)cccc2Cl)NC(=O)NC1C
d) Cn1nnc2cc(C(=O)NCc3ccco3)ccc21
e) COc1ccc(/C=N/NC(=O)c2ccc(Br)cc2)c(OC)c1
Answer: b. N#Cc1ccc(C(=O)OCC(=O)Nc2cccc(S(=O)(=O)N3CCCCC3)c2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
N#Cc1ccc(C(=O)OCC(=O)Nc2cccc(S(=O)(=O)N3CCCCC3)c2)cc1
N#Cc1ccc(C(=O)OCC(=O)Nc2cccc(S(=O)(=O)N3CCCCC3)c2)cc1
[2-oxo-2-(3-piperidin-1-ylsulfonylanilino)ethyl] 4-cyanobenzoate