Task: Answer the multiple-choice question.
Query: Which compound exhibits a 8.001\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
a CCOC(=O)C1CCCN(C(=O)COc2ccc(N(C)S(=O)(=O)c3ccc(C)cc3)cc2)C1
b Cc1cccc([C@@H]2[C@@H]3C(=O)N(Cc4ccccc4)C(=O)[C@@H]3[C@]3(CC(C)C)C(=O)N(c4cccc(F)c4)C(=O)N23)c1
c Cc1ccccc1C(=O)Nc1ccc(C(=O)N/N=C/c2ccc(F)cc2)cc1
Answer: b. Cc1cccc([C@@H]2[C@@H]3C(=O)N(Cc4ccccc4)C(=O)[C@@H]3[C@]3(CC(C)C)C(=O)N(c4cccc(F)c4)C(=O)N23)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cccc([C@@H]2[C@@H]3C(=O)N(Cc4ccccc4)C(=O)[C@@H]3[C@]3(CC(C)C)C(=O)N(c4cccc(F)c4)C(=O)N23)c1
Cc1cccc([C@@H]2[C@@H]3C(=O)N(Cc4ccccc4)C(=O)[C@@H]3[C@]3(CC(C)C)C(=O)N(c4cccc(F)c4)C(=O)N23)c1
(1S,2R,7S,8R)-10-benzyl-4-(3-fluorophenyl)-7-(3-methylphenyl)-2-(2-methylpropyl)-4,6,10-triazatricyclo[6.3.0.02,6]undecane-3,5,9,11-tetrone