Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 13.458\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a C/C=C\C=C/C(=O)Nc1cccc(C2=NOC3(C2)C[C@@H](C(N)=O)N(C(=O)[C@H]2CCC(=O)N2)C3)c1
b O=C1C(C=Nc2ccccc2)=C(O)c2ccccc21
c COc1cccc(CNC(=O)N[C@@H](CC(C)C)C(=O)O)c1
d CCOc1ccccc1NC(=O)COc1coc(CN2CCCc3ccccc32)cc1=O
e COc1ccc(-c2nc3cc(C(=O)O)ccc3n2CCCn2c(-c3ccc(O)c(OC)c3)nc3cc(C(F)(F)F)ccc32)cc1
Answer: d. CCOc1ccccc1NC(=O)COc1coc(CN2CCCc3ccccc32)cc1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccccc1NC(=O)COc1coc(CN2CCCc3ccccc32)cc1=O
CCOc1ccccc1NC(=O)COc1coc(CN2CCCc3ccccc32)cc1=O
2-[6-(3,4-dihydro-2H-quinolin-1-ylmethyl)-4-oxopyran-3-yl]oxy-N-(2-ethoxyphenyl)acetamide