Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 13.360\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(NC2CCCN(Cc3cccc4cnccc34)C2)cc1
(b) COC(=O)[C@@H]1C[C@H]2CC[C@H](O)C[C@H]2N1Cc1ccc(C(C)(C)C)cc1
(c) O=C(C1CC(=O)N(c2ccc(F)cc2)C1)N1CCCCCC1
(d) CC1CCCN(C(=O)Cn2c(-c3nonc3N)nc3ccccc32)C1
(e) O=C(NC1CCN(C(=S)NCc2ccco2)CC1)c1cccc(F)c1
Answer: b. COC(=O)[C@@H]1C[C@H]2CC[C@H](O)C[C@H]2N1Cc1ccc(C(C)(C)C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)[C@@H]1C[C@H]2CC[C@H](O)C[C@H]2N1Cc1ccc(C(C)(C)C)cc1
COC(=O)[C@@H]1C[C@H]2CC[C@H](O)C[C@H]2N1Cc1ccc(C(C)(C)C)cc1
methyl (2S,3aR,6S,7aR)-1-[(4-tert-butylphenyl)methyl]-6-hydroxy-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylate