Problem statement: Answer the MCQ question.
Query: Which compound exhibits a 9.239\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a O=C(OCc1nc2ccc(Cl)cc2n1CCO)c1ccccc1C(=O)c1ccccc1
b CC(C)CNc1nc(=S)nc(N(C)C)[nH]1
c Cc1ccccc1[C@@]1(C)ON(c2ccccc2C(F)(F)F)C1=O
d Nc1cc(=O)[nH]c(SCc2nnc(-c3ccccc3)o2)n1
e COC(=O)C1=C(c2ccccc2)C[C@@H]2CC[C@H]1N2C(=O)NCCCOC(C)C
Answer: e. COC(=O)C1=C(c2ccccc2)C[C@@H]2CC[C@H]1N2C(=O)NCCCOC(C)C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccccc2)C[C@@H]2CC[C@H]1N2C(=O)NCCCOC(C)C
COC(=O)C1=C(c2ccccc2)C[C@@H]2CC[C@H]1N2C(=O)NCCCOC(C)C
methyl (1R,5S)-3-phenyl-8-(3-propan-2-yloxypropylcarbamoyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate