Problem statement: Answer the MCQ question.
Question: Which compound has a -25.212\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] O=C(NCc1ccccc1Cl)C1CCN(S(=O)(=O)c2ccc(N3CCCC3=O)cc2)CC1
[b] Cc1cccc(C2Nc3ccccc3C(=O)N2CCc2ccccc2)n1
[c] COc1cc(C(C2C(=O)CC(C)(C)CC2=O)C2C(=O)CC(C)(C)CC2=O)ccc1OC(C)=O
[d] COc1ccccc1NC(=S)N1C2CCC1CC(NC(=O)NC13CC4CC(CC(C4)C1)C3)C2
Answer: d. COc1ccccc1NC(=S)N1C2CCC1CC(NC(=O)NC13CC4CC(CC(C4)C1)C3)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1NC(=S)N1C2CCC1CC(NC(=O)NC13CC4CC(CC(C4)C1)C3)C2
COc1ccccc1NC(=S)N1C2CCC1CC(NC(=O)NC13CC4CC(CC(C4)C1)C3)C2
1-(1-adamantyl)-3-[8-[(2-methoxyphenyl)carbamothioyl]-8-azabicyclo[3.2.1]octan-3-yl]urea