Task: Answer the multiple choice question.
Question: Which drug exhibits a -1.440\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CCn1cc(CN2CCCC(C(=O)Nc3cccc(-c4cc5ccccc5[nH]4)c3)C2)c(C)n1
b. CC(=O)Nc1nc(-c2ccccc2)cc(-c2ccco2)c1C#N
c. O=S(=O)(c1ccc(OCC(O)CN2CCCC2)cc1)N1CCOCC1
d. CS(=O)(=O)N(CCc1ccccc1)CC(=O)N1CCc2ccccc2C1
e. COc1ccc2c(c1)C(=O)N(c1ccccc1OC)C(=O)C2(C)C
Answer: e. COc1ccc2c(c1)C(=O)N(c1ccccc1OC)C(=O)C2(C)C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2c(c1)C(=O)N(c1ccccc1OC)C(=O)C2(C)C
COc1ccc2c(c1)C(=O)N(c1ccccc1OC)C(=O)C2(C)C
7-methoxy-2-(2-methoxyphenyl)-4,4-dimethylisoquinoline-1,3-dione