Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a 0.413\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CCc1ccc(-c2nc(CSCC(=O)N3CCN(c4ccccn4)CC3)c(C)o2)cc1
b.) Cc1ncoc1C(=O)Nc1ccccc1-c1ccccc1
c.) COc1cccc(CNC(=O)c2ccc3c(c2)S(=O)(=O)N=C2CCCCCN23)c1
d.) O=C(Cn1nc(-c2ccccc2Cl)ccc1=O)Nc1ccc(Br)cc1
e.) COc1ccc(-c2nc3ccccc3o2)cc1NC(=O)CSc1ccc(Cl)cc1
Answer: c. COc1cccc(CNC(=O)c2ccc3c(c2)S(=O)(=O)N=C2CCCCCN23)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(CNC(=O)c2ccc3c(c2)S(=O)(=O)N=C2CCCCCN23)c1
COc1cccc(CNC(=O)c2ccc3c(c2)S(=O)(=O)N=C2CCCCCN23)c1
N-[(3-methoxyphenyl)methyl]-5,5-dioxo-8,9,10,11-tetrahydro-7H-azepino[2,1-c][1,2,4]benzothiadiazine-3-carboxamide