Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 16.172\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a or b without using any additional words.
Options:
a) COc1cc(C2C(C#N)=C(N)Oc3n[nH]c(-c4cccnc4)c32)cc(Br)c1O
b) COC(=O)[C@@H](NC(=O)NC1CCCCC1C)C(C)C
Answer: a. COc1cc(C2C(C#N)=C(N)Oc3n[nH]c(-c4cccnc4)c32)cc(Br)c1O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(C2C(C#N)=C(N)Oc3n[nH]c(-c4cccnc4)c32)cc(Br)c1O
COc1cc(C2C(C#N)=C(N)Oc3n[nH]c(-c4cccnc4)c32)cc(Br)c1O
6-amino-4-(3-bromo-4-hydroxy-5-methoxyphenyl)-3-pyridin-3-yl-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile