Problem statement: Answer the MCQ question.
Question: Which drug has a 11.578\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) O=C(NCC1CCCO1)c1ccc(Cl)c(S(=O)(=O)N2CCCCC2)c1
b.) COC(=O)C1C(=O)C=C(Nc2ccc(F)cc2F)CC1c1ccccc1
c.) CCOc1ccccc1C1C(C#N)=C(N)N(N(C)C)C2=C1C(=O)CCC2
d.) O=C(O)CCC(=O)N1CCN(c2ncccc2C(F)(F)F)CC1
e.) COc1cc(OC)c(C2N(c3ccc(Cl)cc3)C(=O)C3CCCN32)cc1OC
Answer: d. O=C(O)CCC(=O)N1CCN(c2ncccc2C(F)(F)F)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(O)CCC(=O)N1CCN(c2ncccc2C(F)(F)F)CC1
O=C(O)CCC(=O)N1CCN(c2ncccc2C(F)(F)F)CC1
4-oxo-4-[4-[3-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]butanoic acid