Task: Answer the MCQ question.
Question: Which compound has a -0.402\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1ccc(NC(=O)c2cccc(S(=O)(=O)N3CCCc4ccccc43)c2)nc1
b) COc1ccc(OC)c(CCNC(=O)c2cccc(NC3=NC4CS(=O)(=O)CC4S3)c2)c1
c) Cc1ccc(CN2CCN(Cc3cnn(-c4ccc(Cl)cc4)c3)CC2CCO)o1
d) OCc1nc2ccccc2n1/N=C/c1cccs1
e) CCCCc1ccc(NS(=O)(=O)c2cccs2)cc1
Answer: b. COc1ccc(OC)c(CCNC(=O)c2cccc(NC3=NC4CS(=O)(=O)CC4S3)c2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(OC)c(CCNC(=O)c2cccc(NC3=NC4CS(=O)(=O)CC4S3)c2)c1
COc1ccc(OC)c(CCNC(=O)c2cccc(NC3=NC4CS(=O)(=O)CC4S3)c2)c1
N-[2-(2,5-dimethoxyphenyl)ethyl]-3-[(5,5-dioxo-3a,4,6,6a-tetrahydrothieno[3,4-d][1,3]thiazol-2-yl)amino]benzamide