Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -25.679\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COc1ccc(C)cc1NC(=O)CN1CCCN(S(=O)(=O)c2ccc(Br)cc2)CC1
(b) Cc1cc(C)nc(NC(=O)/C=C/c2ccc3c(c2)OCO3)c1
(c) CN1CCN(C(=O)Nc2cccc3ccccc23)CC1
(d) CN1CCCN(C(=O)/C=C/c2ccc(Cl)cc2Cl)CC1.Cl
(e) COc1ccccc1N(CC(=O)NC1CCCCC1)C(=O)CNC(=O)c1cccs1
Answer: d. CN1CCCN(C(=O)/C=C/c2ccc(Cl)cc2Cl)CC1.Cl
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1CCCN(C(=O)/C=C/c2ccc(Cl)cc2Cl)CC1.Cl
CN1CCCN(C(=O)/C=C/c2ccc(Cl)cc2Cl)CC1.Cl
(E)-3-(2,4-dichlorophenyl)-1-(4-methyl-1,4-diazepan-1-yl)prop-2-en-1-one;hydrochloride