Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -4.578\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccccc1CNC(=O)COC(=O)c1ccccn1
b) C=CCn1c(SCC(=O)c2cc(C)n(CC3CCCO3)c2C)nc2sc(C)c(C)c2c1=O
c) CCN(c1ccc(NC(=O)COC(=O)CCc2nc3ccccc3n2-c2ccccc2)cc1)C(C)C
d) CN1CCN(c2c[nH]c(=O)[nH]c2=O)CC1
e) Cc1c(C(=O)O)sc2nc(CSc3nnc(-c4ccc(F)cc4)n3C)[nH]c(=O)c12
Answer: d. CN1CCN(c2c[nH]c(=O)[nH]c2=O)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1CCN(c2c[nH]c(=O)[nH]c2=O)CC1
CN1CCN(c2c[nH]c(=O)[nH]c2=O)CC1
5-(4-methylpiperazin-1-yl)-1H-pyrimidine-2,4-dione