Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -28.842\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) Cc1ccc(C(=O)NC(=S)NCc2cccnc2)c(C)c1
b.) O=C(CCc1nc2ccccc2c(=O)[nH]1)N1CCN(c2ccc(F)cc2)CC1
c.) C/C(Cc1ccccc1)=N\NC(=O)CNC(=O)c1cccc(Br)c1
d.) COc1ccc([C@H]2CC(=O)C=C(/C=C/c3ccccc3)C2)cc1
Answer: b. O=C(CCc1nc2ccccc2c(=O)[nH]1)N1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CCc1nc2ccccc2c(=O)[nH]1)N1CCN(c2ccc(F)cc2)CC1
O=C(CCc1nc2ccccc2c(=O)[nH]1)N1CCN(c2ccc(F)cc2)CC1
2-[3-[4-(4-fluorophenyl)piperazin-1-yl]-3-oxopropyl]-3H-quinazolin-4-one