Problem statement: Answer the MCQ question.
Question: What is the human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM of a compound with the SMILES COc1ccc(N2CCN(C(=O)CNC(=O)Cn3cnc4sc(C)c(C)c4c3=O)CC2)cc1?
Constraint: You must return none, one or more options from a, b, c, or d without using any additional words.
Options:
a. -8.753
b. 9.318
c. 10.871
d. 7.294
Answer: b. 9.318\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
COc1ccc(N2CCN(C(=O)CNC(=O)Cn3cnc4sc(C)c(C)c4c3=O)CC2)cc1
COc1ccc(N2CCN(C(=O)CNC(=O)Cn3cnc4sc(C)c(C)c4c3=O)CC2)cc1
2-(5,6-dimethyl-4-oxothieno[2,3-d]pyrimidin-3-yl)-N-[2-[4-(4-methoxyphenyl)piperazin-1-yl]-2-oxoethyl]acetamide