Problem statement: Answer the MCQ question.
Question: Which drug has a 3.439\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COc1ccc(OCc2nn3c(-c4cccc(OC)c4)nnc3s2)cc1
b.) CC(C)c1ccc(NC2CCCN(C(=O)c3cccnc3)C2)cc1
c.) CN(C)CCN1C(=O)C(=O)/C(=C(/O)c2ccccc2)C1c1ccccc1F
d.) Cc1ccc2c(c1)CCCN2C(=O)CCc1nc2ccccc2c(=O)[nH]1
e.) COc1cc2cc(CN(CCN3CCCC3)C(=O)Nc3ccc(F)cc3)c(=O)[nH]c2cc1OC
Answer: d. Cc1ccc2c(c1)CCCN2C(=O)CCc1nc2ccccc2c(=O)[nH]1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc2c(c1)CCCN2C(=O)CCc1nc2ccccc2c(=O)[nH]1
Cc1ccc2c(c1)CCCN2C(=O)CCc1nc2ccccc2c(=O)[nH]1
2-[3-(6-methyl-3,4-dihydro-2H-quinolin-1-yl)-3-oxopropyl]-3H-quinazolin-4-one