Problem statement: Answer the multiple choice question.
Query: Which compound has a -1.777\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C(CSCc1ccc(Cl)cc1)N/N=C/c1ccc(OCC(=O)Nc2ccccc2)cc1
b) CSCC(=O)N1CCCC(CNC(=O)c2ccc(-c3ccccc3)cc2)C1
c) COc1ccc(CNC(=O)CN2CCN(S(=O)(=O)c3ccccc3)CC2)cc1
d) Cc1ccc(-c2cc(C(F)(F)F)n3nc(C(=O)NCCCn4ccnc4)cc3n2)cc1C
e) O=C(Nc1cccc2ncccc12)c1ccccc1Cl
Answer: b. CSCC(=O)N1CCCC(CNC(=O)c2ccc(-c3ccccc3)cc2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CSCC(=O)N1CCCC(CNC(=O)c2ccc(-c3ccccc3)cc2)C1
CSCC(=O)N1CCCC(CNC(=O)c2ccc(-c3ccccc3)cc2)C1
N-[[1-(2-methylsulfanylacetyl)piperidin-3-yl]methyl]-4-phenylbenzamide