Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a 1.375\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] O=C(COC(=O)[C@@H]1CC(O)CN1S(=O)(=O)c1ccc(Cl)cc1)NC(=O)NCc1ccccc1
[b] O=C(CCSc1ccc(Cl)cc1)c1ccco1
[c] CCOC(CNC(=O)c1ccc(CNC(=O)c2ccc(OC)c(OC)c2)cc1)OCC
[d] CCn1c(COc2cccc(C)c2)nc2ccccc21
[e] COc1cc(/C=N/n2cnnc2)ccc1OC(=O)c1cccnc1
Answer: a. O=C(COC(=O)[C@@H]1CC(O)CN1S(=O)(=O)c1ccc(Cl)cc1)NC(=O)NCc1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COC(=O)[C@@H]1CC(O)CN1S(=O)(=O)c1ccc(Cl)cc1)NC(=O)NCc1ccccc1
O=C(COC(=O)[C@@H]1CC(O)CN1S(=O)(=O)c1ccc(Cl)cc1)NC(=O)NCc1ccccc1
[2-(benzylcarbamoylamino)-2-oxoethyl] (2S)-1-(4-chlorophenyl)sulfonyl-4-hydroxypyrrolidine-2-carboxylate