Problem statement: Answer the multiple choice question.
Query: Which compound has a 1.670\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a O=C(COc1ccccc1F)Nc1nnc(C2CCCC2)s1
b O=C(c1cc2cc(F)ccc2[nH]1)N(Cc1cccnc1)CC1CCCN(C2CCCCC2)C1
c O=C(c1ccccc1)C1CCN(c2ncccc2[N+](=O)[O-])CC1
d NS(=O)(=O)c1ccc(CCNC(=O)c2ccc(C(=O)c3ccccc3)cc2)cc1
e O=C(COC(=O)[C@@H]1CC(O)CN1S(=O)(=O)c1ccc([N+](=O)[O-])cc1)NC12CC3CC(CC(C3)C1)C2
Answer: e. O=C(COC(=O)[C@@H]1CC(O)CN1S(=O)(=O)c1ccc([N+](=O)[O-])cc1)NC12CC3CC(CC(C3)C1)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COC(=O)[C@@H]1CC(O)CN1S(=O)(=O)c1ccc([N+](=O)[O-])cc1)NC12CC3CC(CC(C3)C1)C2
O=C(COC(=O)[C@@H]1CC(O)CN1S(=O)(=O)c1ccc([N+](=O)[O-])cc1)NC12CC3CC(CC(C3)C1)C2
[2-(1-adamantylamino)-2-oxoethyl] (2S)-4-hydroxy-1-(4-nitrophenyl)sulfonylpyrrolidine-2-carboxylate