Problem statement: Answer the MCQ question.
Question: Which drug has a 2.338\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) COC(=O)Cc1c(C)c2ccc(OCC(C)=O)c(C)c2oc1=O
(b) CCN1C(=O)N[C@@H](c2cccc(C(F)(F)F)c2)[C@H](C(=O)OC)[C@H]1C
(c) COCCNC(=O)CCCn1c(=O)c2cc(OC)c(OC)cc2n(CC(=O)NCCC2=CCCCC2)c1=O
(d) CCCCn1c(N)c(N(CCOC)C(=O)COC(=O)/C=C/c2ccc(Br)cc2)c(=O)[nH]c1=O
Answer: d. CCCCn1c(N)c(N(CCOC)C(=O)COC(=O)/C=C/c2ccc(Br)cc2)c(=O)[nH]c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCn1c(N)c(N(CCOC)C(=O)COC(=O)/C=C/c2ccc(Br)cc2)c(=O)[nH]c1=O
CCCCn1c(N)c(N(CCOC)C(=O)COC(=O)/C=C/c2ccc(Br)cc2)c(=O)[nH]c1=O
[2-[(6-amino-1-butyl-2,4-dioxopyrimidin-5-yl)-(2-methoxyethyl)amino]-2-oxoethyl] (E)-3-(4-bromophenyl)prop-2-enoate