Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a 10.598\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CC(C)c1ccc(N(CC(=O)N/N=C/c2ccc(OC3CSC3)cc2)S(=O)(=O)c2ccccc2)cc1
b.) CC(=O)NC12CC3CC(C1)CC(C(=O)Nc1nc4ccc(F)cc4s1)(C3)C2
c.) CC(C)(C)C(=O)Nc1ccc(N2CCN(S(C)(=O)=O)CC2)cc1
d.) Oc1[nH]c2ccccc2c1N=Nc1ccc(C(F)(F)F)cn1
e.) O=S1(=O)CCC(NC(=S)SCCOc2ccccc2)C1
Answer: c. CC(C)(C)C(=O)Nc1ccc(N2CCN(S(C)(=O)=O)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC(C)(C)C(=O)Nc1ccc(N2CCN(S(C)(=O)=O)CC2)cc1
CC(C)(C)C(=O)Nc1ccc(N2CCN(S(C)(=O)=O)CC2)cc1
2,2-dimethyl-N-[4-(4-methylsulfonylpiperazin-1-yl)phenyl]propanamide