Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -16.011\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) O=C(O)C1CCCN(C(=O)c2cccc3ccccc23)C1
b.) Cc1ccc(NC(=O)CN(C)C(=O)Cc2ccc(Cl)c(Cl)c2)cc1
c.) COCCc1ccc(OCC(O)CNC(C)C)cc1.O=C(O)C(O)C(O)C(=O)O
d.) COc1ccc(C(=O)C2CCN(CC(=O)NCc3ccccc3)CC2)cc1
e.) O=C(OCc1nc2ccccc2s1)C1CCN(S(=O)(=O)c2cccs2)CC1
Answer: d. COc1ccc(C(=O)C2CCN(CC(=O)NCc3ccccc3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)C2CCN(CC(=O)NCc3ccccc3)CC2)cc1
COc1ccc(C(=O)C2CCN(CC(=O)NCc3ccccc3)CC2)cc1
N-benzyl-2-[4-(4-methoxybenzoyl)piperidin-1-yl]acetamide