Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -11.682\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) CCC(c1nnnn1CS(=O)(=O)c1ccc(C)cc1)N1CCN(c2nc3ccccc3s2)CC1
b) CC(C)Cn1c(=O)c(C(=O)Nc2ccccc2S(N)(=O)=O)c(O)c2ccccc21
c) CC(C)(C)c1cc[n+](-c2[nH]c(=O)sc2/C=N/NC([S-])=Nc2ccccc2)cc1
d) C=CCn1c(SCC(=O)NCCOC)nc2scc(-c3ccco3)c2c1=O
Answer: d. C=CCn1c(SCC(=O)NCCOC)nc2scc(-c3ccco3)c2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C=CCn1c(SCC(=O)NCCOC)nc2scc(-c3ccco3)c2c1=O
C=CCn1c(SCC(=O)NCCOC)nc2scc(-c3ccco3)c2c1=O
2-[5-(furan-2-yl)-4-oxo-3-prop-2-enylthieno[2,3-d]pyrimidin-2-yl]sulfanyl-N-(2-methoxyethyl)acetamide