Task: Answer the multiple choice question.
Question: Which drug has a -49.183\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) O=c1[nH]cnc2c1sc1nc3c(c(-c4ccc(Cl)cc4)c12)CCC3
b.) COc1ccc(S(=O)(=O)Nc2ccccn2)cc1C(=O)Nc1ccccc1
c.) COc1ccc(C[C@H]2CN3C(=NC[C@H]3Cc3ccccc3)N2CCNC(=O)CCC2CCCCC2)cc1
d.) Cc1ccc(C)c(N2CN(Cc3ccco3)CNC2=S)c1
e.) Cc1cc(C)n(CCNC(=O)c2ccc3c(c2)OCO3)n1
Answer: c. COc1ccc(C[C@H]2CN3C(=NC[C@H]3Cc3ccccc3)N2CCNC(=O)CCC2CCCCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C[C@H]2CN3C(=NC[C@H]3Cc3ccccc3)N2CCNC(=O)CCC2CCCCC2)cc1
COc1ccc(C[C@H]2CN3C(=NC[C@H]3Cc3ccccc3)N2CCNC(=O)CCC2CCCCC2)cc1
N-[2-[(3R,6S)-3-benzyl-6-[(4-methoxyphenyl)methyl]-2,3,5,6-tetrahydroimidazo[1,2-a]imidazol-7-yl]ethyl]-3-cyclohexylpropanamide