Problem statement: Answer the multiple-choice question.
Query: Which drug has a 12.438\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccc(CCn2c(O)c(C=Nc3ccc(NC(C)=O)cc3)c(=O)[nH]c2=O)cc1OC
b) COc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3c(c2)CC(C)N3C(C)=O)cc1OC
c) CCOc1ccc(NC(=O)N2CCC(NC(=O)C(Cc3ccc(OC)c(OC)c3)NC(C)=O)CC2)cc1
d) Cc1ccc(NC(=O)CNC(=O)c2cccc(Cl)c2)nc1
e) CCOC(=O)C1CCCN(CCC(=O)Nc2c(C(=O)OC)[nH]c3cc(OC)ccc23)C1
Answer: b. COc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3c(c2)CC(C)N3C(C)=O)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3c(c2)CC(C)N3C(C)=O)cc1OC
COc1ccc(NC(=O)CN(C)S(=O)(=O)c2ccc3c(c2)CC(C)N3C(C)=O)cc1OC
2-[(1-acetyl-2-methyl-2,3-dihydroindol-5-yl)sulfonyl-methylamino]-N-(3,4-dimethoxyphenyl)acetamide