Problem statement: Answer the multiple-choice question.
Question: Which drug has a -2.494\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a O=C(c1ccco1)N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1
b CN(CC(=O)Nc1cccc(F)c1)C(=O)/C=C/c1cn(Cc2ccccc2)nc1-c1cccnc1
c COc1ccc(OC)c(NC(=O)C2CC(=O)N(CCc3ccccc3)C2)c1
d CCOC(=O)C1(Cc2ccccc2C(F)(F)F)CCN(C2CCSC2)CC1
e CCOc1ccc2nc(SCC(=O)NCc3ccc(S(N)(=O)=O)cc3)sc2c1
Answer: d. CCOC(=O)C1(Cc2ccccc2C(F)(F)F)CCN(C2CCSC2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1(Cc2ccccc2C(F)(F)F)CCN(C2CCSC2)CC1
CCOC(=O)C1(Cc2ccccc2C(F)(F)F)CCN(C2CCSC2)CC1
ethyl 1-(thiolan-3-yl)-4-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxylate