Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 19.951\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) O=C1c2ccccc2C(=O)N1CC(O)CN1CCOCC1
(b) COc1ccccc1CNC(=O)CCCNC(=O)c1ccc(Cl)cc1
(c) COc1ccc(/C=N/OCc2ccc(Br)cc2)c(OC)c1
(d) NC(=O)c1ccc(NC(=O)CCc2nc3sc4c(c3c(=O)[nH]2)CCCC4)cc1
(e) Cc1ccc(NC(=O)C(c2ccccc2)N2CCN(C(=O)c3ccco3)CC2)cc1Cl
Answer: b. COc1ccccc1CNC(=O)CCCNC(=O)c1ccc(Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1CNC(=O)CCCNC(=O)c1ccc(Cl)cc1
COc1ccccc1CNC(=O)CCCNC(=O)c1ccc(Cl)cc1
4-chloro-N-[4-[(2-methoxyphenyl)methylamino]-4-oxobutyl]benzamide