Problem statement: Answer the multiple choice question.
Query: Which drug has a -22.989\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccc(S(=O)(=O)Cc2ccc(C(=O)NCCCN3CCc4ccccc4C3)o2)cc1
(b) CCOc1ccc(C(=O)Nc2cnn(Cc3ccc(Cl)c(Cl)c3)c2)cc1
(c) O=C(NNc1ccccc1F)C1CCC1
(d) CC(=O)Nc1sc(/C(C#N)=C\c2cccc(Cl)c2)nc1-c1ccc(C)cc1
(e) CSCCC(NC(=O)c1ccco1)C(=O)N1CC(C)OC(C)C1
Answer: a. COc1ccc(S(=O)(=O)Cc2ccc(C(=O)NCCCN3CCc4ccccc4C3)o2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)Cc2ccc(C(=O)NCCCN3CCc4ccccc4C3)o2)cc1
COc1ccc(S(=O)(=O)Cc2ccc(C(=O)NCCCN3CCc4ccccc4C3)o2)cc1
N-[3-(3,4-dihydro-1H-isoquinolin-2-yl)propyl]-5-[(4-methoxyphenyl)sulfonylmethyl]furan-2-carboxamide