Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -0.367\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COCCNC(=O)CN(C(=O)c1ccc(N2CCCC2)nc1)c1ccccc1
b) O=C(O)c1nn2c(c1Br)NC(c1ccccc1)CC2C(F)(F)F
c) CCc1ccc(C(=O)NNC(=O)c2ccc(OCC(=O)N3CCOCC3)c(OC)c2)cc1
d) CCc1nc(C)cn1S(=O)(=O)c1cc(Br)c(C)cc1OC
e) CCOC(=O)C1CCN(C(c2cc3c(C)ccc(C)c3[nH]c2=O)c2nnnn2C2CCCCC2)CC1
Answer: e. CCOC(=O)C1CCN(C(c2cc3c(C)ccc(C)c3[nH]c2=O)c2nnnn2C2CCCCC2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1CCN(C(c2cc3c(C)ccc(C)c3[nH]c2=O)c2nnnn2C2CCCCC2)CC1
CCOC(=O)C1CCN(C(c2cc3c(C)ccc(C)c3[nH]c2=O)c2nnnn2C2CCCCC2)CC1
ethyl 1-[(1-cyclohexyltetrazol-5-yl)-(5,8-dimethyl-2-oxo-1H-quinolin-3-yl)methyl]piperidine-4-carboxylate