Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -10.584\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) COC(=O)CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)Oc1ccccc1
(b) NNC(=O)c1nnn(-c2nonc2N)c1-c1cccs1
(c) COc1ccc(N2CCN(C(CNC(=O)C(=O)NCC3CCCO3)c3ccco3)CC2)cc1
(d) C=CCc1cccc(OC)c1OCCOCCNCCO.O=C(O)C(=O)O
(e) CN1CCN(C(=O)c2ccccc2NC(=O)c2ccccc2)CC1
Answer: b. NNC(=O)c1nnn(-c2nonc2N)c1-c1cccs1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
NNC(=O)c1nnn(-c2nonc2N)c1-c1cccs1
NNC(=O)c1nnn(-c2nonc2N)c1-c1cccs1
1-(4-amino-1,2,5-oxadiazol-3-yl)-5-(thiophen-2-yl)triazole-4-carbohydrazide