Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a 7.386\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: Cc1cccc(NS(=O)(=O)c2ccc(C(=O)N3CCC3)cc2)c1C
b: COc1cccc(NC(=S)N(CCC(C)C)C2CCN(C(C)=O)CC2)c1
c: Cc1[nH]n(C(N)=S)c(=O)c1N=Nc1ccc(Br)cc1
d: CN(C)S(=O)(=O)N(CC(=O)Nc1cccc(F)c1)c1ccccc1
e: COC(=O)C1N[C@@H]([C@@H](NC(=O)COc2ccccc2)C(=O)NCc2ccsc2)SC1(C)C
Answer: e. COC(=O)C1N[C@@H]([C@@H](NC(=O)COc2ccccc2)C(=O)NCc2ccsc2)SC1(C)C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1N[C@@H]([C@@H](NC(=O)COc2ccccc2)C(=O)NCc2ccsc2)SC1(C)C
COC(=O)C1N[C@@H]([C@@H](NC(=O)COc2ccccc2)C(=O)NCc2ccsc2)SC1(C)C
methyl (2R)-5,5-dimethyl-2-[(1S)-2-oxo-1-[(2-phenoxyacetyl)amino]-2-(thiophen-3-ylmethylamino)ethyl]-1,3-thiazolidine-4-carboxylate