Problem statement: Answer the MCQ question.
Query: Which compound has a -6.572\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
(a) COc1ccc(C(=O)Nc2c(C(C)(C)C)nn(C)c2C(C)(C)C)cc1
(b) CCC1=C(OC(=O)N(CC)CC)N2C(=O)OC(=NCC(=O)OC)[C@]2(C)[C@H]2C1=CC[C@H]1C(=O)N(C)C(=O)[C@H]12
(c) Cc1ccc(NC(=O)CSCC(=O)Nc2ccc(N3CCOCC3)c(Cl)c2)cc1
(d) O=C(CSC1CN(C(c2ccccc2)c2ccccc2)C1)N/N=C/c1ccccc1
Answer: b. CCC1=C(OC(=O)N(CC)CC)N2C(=O)OC(=NCC(=O)OC)[C@]2(C)[C@H]2C1=CC[C@H]1C(=O)N(C)C(=O)[C@H]12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCC1=C(OC(=O)N(CC)CC)N2C(=O)OC(=NCC(=O)OC)[C@]2(C)[C@H]2C1=CC[C@H]1C(=O)N(C)C(=O)[C@H]12
CCC1=C(OC(=O)N(CC)CC)N2C(=O)OC(=NCC(=O)OC)[C@]2(C)[C@H]2C1=CC[C@H]1C(=O)N(C)C(=O)[C@H]12
methyl2-[[(1R,2S,12R,16S)-7-(diethylcarbamoyloxy)-8-ethyl-2,14-dimethyl-5,13,15-trioxo-4-oxa-6,14-diazatetracyclo[7.7.0.02,6.012,16]hexadeca-7,9-dien-3-ylidene]amino]acetate