Problem statement: Answer the MCQ question.
Question: Which drug has a 1.809\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCC(=NCCN1CCNCC1)C1=C(O)CC(C)(C)CC1=O
b) CCOC(=O)C1CCCN(C(=O)c2cc(-c3ccc(F)cc3)nc3ccccc23)C1
c) CC(=O)N1CCc2cc(S(=O)(=O)CCC(=O)N(C)c3cc(C)ccc3C)ccc21
d) COc1ccc(N2CCN(C(=O)c3ccc(CS(=O)c4cccc(C)c4)o3)CC2)cc1
e) Cc1coc2cc3oc(=O)c(CCC(=O)NCCCN4CCCC4=O)c(C)c3cc12
Answer: d. COc1ccc(N2CCN(C(=O)c3ccc(CS(=O)c4cccc(C)c4)o3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(C(=O)c3ccc(CS(=O)c4cccc(C)c4)o3)CC2)cc1
COc1ccc(N2CCN(C(=O)c3ccc(CS(=O)c4cccc(C)c4)o3)CC2)cc1
[4-(4-methoxyphenyl)piperazin-1-yl]-[5-[(3-methylphenyl)sulfinylmethyl]furan-2-yl]methanone