Problem statement: Answer the MCQ question.
Question: Which compound has a 21.077\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)C3C4C=CC(C4)C3C(=O)O)cc2)n1
(b) Cc1ccc(Nc2nnc(SCc3cc(=O)n4cc(C)ccc4n3)s2)cc1
(c) CCCCN(CC)CCCNC(=O)c1ccc(CS(=O)(=O)c2c(Cl)cccc2Cl)o1
(d) CCNC(=O)CSc1ncnc2sccc12
(e) CCCNC(=S)Nc1ccccc1
Answer: a. Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)C3C4C=CC(C4)C3C(=O)O)cc2)n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)C3C4C=CC(C4)C3C(=O)O)cc2)n1
Cc1ccnc(NS(=O)(=O)c2ccc(NC(=O)C3C4C=CC(C4)C3C(=O)O)cc2)n1
3-[[4-[(4-methylpyrimidin-2-yl)sulfamoyl]phenyl]carbamoyl]bicyclo[2.2.1]hept-5-ene-2-carboxylic acid