Task: Answer the multiple-choice question.
Query: Which drug has a -2.255\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccc(/C=N/n2c(-c3n[nH]c4c3CCC4)n[nH]c2=S)cc1OC
b) CC(C)C(c1nnnn1Cc1ccccc1)N1CCc2ccccc2C1
c) Clc1ccccc1Cn1nnc2c(NCCN3CCOCC3)ncnc21
d) Cc1ccc(-n2nc(C)c(/C=N/NC(=O)c3cccs3)c2Cl)cc1
e) COc1ccc(N(C)C(=O)c2cc3c(Cl)nc4ccccc4c3s2)cc1
Answer: e. COc1ccc(N(C)C(=O)c2cc3c(Cl)nc4ccccc4c3s2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N(C)C(=O)c2cc3c(Cl)nc4ccccc4c3s2)cc1
COc1ccc(N(C)C(=O)c2cc3c(Cl)nc4ccccc4c3s2)cc1
4-chloro-N-(4-methoxyphenyl)-N-methylthieno[3,2-c]quinoline-2-carboxamide