Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 11.168\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a: O=C(Nc1ccccc1)/C(=C\c1ccc(F)cc1)NC(=O)c1ccco1
b: COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccc(OC)cc1
c: O=C(COC(=O)CCCN=C1NS(=O)(=O)c2ccccc21)NC(=O)NC1CCCC1
d: CCCNc1c(NS(=O)(=O)c2ccc(Br)cc2)c(=O)oc2ccccc12
Answer: b. COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccc(OC)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccc(OC)cc1
COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)NCCOc1ccc(OC)cc1
methyl (1R,5S)-3-(3-fluoro-4-phenylphenyl)-8-[2-(4-methoxyphenoxy)ethylcarbamoyl]-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate