Problem statement: Answer the MCQ question.
Query: Which compound exhibits a 3.536\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccc(-c2c(C#Cc3ccsc3)c3cc(-c4ccc(OC)c(F)c4)ccc3n2C)cc1
b) N=c1c(S(=O)(=O)c2ccc(Cl)cc2)cc2c(=O)n3ccccc3nc2n1Cc1cccnc1
c) COC(=O)c1ccccc1NC(=O)N1CCN(Cc2ccco2)CC1
d) COC(=O)CCc1nc2c(C#N)c(-c3ccc(Cl)cc3)ccn2n1
e) Cc1ccccc1C(=O)NC1CCN(CC(=O)NCc2ccc(F)cc2)CC1
Answer: d. COC(=O)CCc1nc2c(C#N)c(-c3ccc(Cl)cc3)ccn2n1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)CCc1nc2c(C#N)c(-c3ccc(Cl)cc3)ccn2n1
COC(=O)CCc1nc2c(C#N)c(-c3ccc(Cl)cc3)ccn2n1
methyl 3-[7-(4-chlorophenyl)-8-cyano-[1,2,4]triazolo[1,5-a]pyridin-2-yl]propanoate