Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 18.862\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] O=C(CC(=O)Nc1ccccc1)Nc1ccccc1
[b] COc1ccc(S(=O)(=O)N(CCc2ccccc2)CC(=O)NC(C)C)cc1
[c] COc1ccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCc2ccc(F)cc2)c2ccc(O)cc2)cc1
[d] O=C1CCCCN1CCC(=O)N1CCCC(N2CCN(c3ccccc3)CC2)C1
[e] CC1CN(C(=O)COC(=O)c2ccc(N)c([N+](=O)[O-])c2)CC(C)O1
Answer: c. COc1ccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCc2ccc(F)cc2)c2ccc(O)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCc2ccc(F)cc2)c2ccc(O)cc2)cc1
COc1ccc(N(C(=O)c2snc(C(N)=O)c2N)C(C(=O)NCc2ccc(F)cc2)c2ccc(O)cc2)cc1
4-amino-5-N-[2-[(4-fluorophenyl)methylamino]-1-(4-hydroxyphenyl)-2-oxoethyl]-5-N-(4-methoxyphenyl)-1,2-thiazole-3,5-dicarboxamide