Problem statement: Answer the MCQ question.
Query: Which compound has a -12.828\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) CCCC(=O)N(c1ccc(OC)cc1)C1C=CS(=O)(=O)C1
(b) CCOc1ccc(NC(=S)NC23CC4CC(CC(C4)C2)C3)cc1
(c) Cc1nc2scc(C)n2c(=O)c1S(=O)(=O)NCC1CCN(Cc2ccc(Cl)cc2)CC1
(d) O=C(/C=C/c1ccc2c(c1)OCO2)N1CCN(c2ccc(Cl)cc2)CC1
Answer: c. Cc1nc2scc(C)n2c(=O)c1S(=O)(=O)NCC1CCN(Cc2ccc(Cl)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1nc2scc(C)n2c(=O)c1S(=O)(=O)NCC1CCN(Cc2ccc(Cl)cc2)CC1
Cc1nc2scc(C)n2c(=O)c1S(=O)(=O)NCC1CCN(Cc2ccc(Cl)cc2)CC1
N-[[1-[(4-chlorophenyl)methyl]piperidin-4-yl]methyl]-3,7-dimethyl-5-oxo-[1,3]thiazolo[3,2-a]pyrimidine-6-sulfonamide