Problem statement: Answer the multiple-choice question.
Question: Which drug has a -0.230\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCc1ccccc1S(=O)(=O)Cc1ccc(C(=O)NCc2cccs2)o1
b. O=C(CC1NC(=O)NC1=O)Nc1ccccc1
c. COc1cc(NC(=O)COc2ccc(-n3cnnn3)cc2)c(OC)cc1Cl
d. COc1ccc(NC(=S)N2CCCC2)c(OC)c1
e. Cc1onc(-c2ccccc2)c1C(=O)OCC(=O)Nc1cccc(Cl)c1
Answer: a. CCc1ccccc1S(=O)(=O)Cc1ccc(C(=O)NCc2cccs2)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCc1ccccc1S(=O)(=O)Cc1ccc(C(=O)NCc2cccs2)o1
CCc1ccccc1S(=O)(=O)Cc1ccc(C(=O)NCc2cccs2)o1
5-[(2-ethylphenyl)sulfonylmethyl]-N-(thiophen-2-ylmethyl)furan-2-carboxamide