Problem statement: Answer the multiple choice question.
Query: What is the hERG inhibition at a concentration of 1uM of a drug with the SMILES COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCCC1?
Constraint: You must return none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) 0.064
b.) -5.127
c.) 8.445
d.) 3.376
Answer: b. -5.127\%.
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: What is the {herg_central_at_1uM__names__noun} of a {#compound|drug!} with the {SMILES__description} {SMILES#}?
Constraint: You must return none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{herg_central_at_1uM%SMILES%}
Answer: {%multiple_choice_result}. {herg_central_at_1uM#}{herg_central_at_1uM__units}.
COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCCC1
COC(=O)C1=C(c2ccc(-c3ccccc3)c(F)c2)C[C@@H]2CC[C@H]1N2C(=O)N1CCCC1
methyl (1R,5S)-3-(3-fluoro-4-phenylphenyl)-8-(pyrrolidine-1-carbonyl)-8-azabicyclo[3.2.1]oct-2-ene-2-carboxylate