Problem statement: Answer the MCQ question.
Question: Which compound exhibits a 18.290\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CCCN1C(=O)CC(C(=O)OC)=C1C
b. O=C(N/N=C/c1ccncc1)c1cc(Br)ccc1OCc1ccccc1
c. COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c2cccc(OC)c2OC)c(OC)c1
d. CC(C)NC(=O)/C(C#N)=C/c1cccc(NC(=O)c2ccccc2Cl)c1
e. O=C(/C=C/c1ccc2c(c1)OCO2)N1CCN(c2ccc(Cl)cc2)CC1
Answer: c. COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c2cccc(OC)c2OC)c(OC)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c2cccc(OC)c2OC)c(OC)c1
COc1ccc(NC(=O)C2=C(C)NC(=O)NC2c2cccc(OC)c2OC)c(OC)c1
4-(2,3-dimethoxyphenyl)-N-(2,4-dimethoxyphenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxamide