Problem statement: Answer the multiple choice question.
Question: Which drug has a 6.145\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. Cc1[nH]nc2c1C(CCc1ccccc1)C(C#N)=C(N)O2
b. CSc1cccc(NC(=O)c2cc(S(=O)(=O)N3CCc4ccccc43)cn2C)c1
c. COc1ccc(C(CNC(=O)c2cncc(Br)c2)N(C)C)cc1
d. CC(NC(=O)COC(=O)c1ccc(CO)cc1)C1CC2CCC1C2
e. CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c1ccco1)c1ccc(C(=O)OC)cc1
Answer: e. CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c1ccco1)c1ccc(C(=O)OC)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c1ccco1)c1ccc(C(=O)OC)cc1
CCCC[C@@H]1C[C@H]1[C@@H](NC(=O)c1ccco1)c1ccc(C(=O)OC)cc1
methyl 4-[(R)-[(1R,2R)-2-butylcyclopropyl]-(furan-2-carbonylamino)methyl]benzoate