Problem statement: Answer the multiple choice question.
Query: Which compound exhibits a -8.533\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COCCN(Cc1cc2c(C)cc(C)cc2nc1Cl)C(=O)c1ccccc1F
b COc1cc(C2C(C#N)=C(N)OC3=C2C(=O)CCC3)cc2c1OCO2
c Cc1cc(C)c(S(=O)(=O)N2CCN(C(=O)CN3C(=O)NC4(CCCC4)C3=O)CC2)c(C)c1
d COc1ccccc1OCC(=O)N(Cc1nnc(-c2ccccc2Cl)o1)C1CC1
e CCOC(=O)Cn1nnnc1C(C(C)C)N(Cc1cc2c(C)cc(C)cc2[nH]c1=O)C1CCCC1
Answer: d. COc1ccccc1OCC(=O)N(Cc1nnc(-c2ccccc2Cl)o1)C1CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1OCC(=O)N(Cc1nnc(-c2ccccc2Cl)o1)C1CC1
COc1ccccc1OCC(=O)N(Cc1nnc(-c2ccccc2Cl)o1)C1CC1
N-[[5-(2-chlorophenyl)-1,3,4-oxadiazol-2-yl]methyl]-N-cyclopropyl-2-(2-methoxyphenoxy)acetamide