Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -17.482\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
(a) CCOc1cc(C=O)c(Br)cc1OC1CCCC1
(b) COC(=O)c1cc(S(=O)(=O)NCC2CCN(CCc3ccc(OC)cc3)CC2)cn1C
(c) Cc1ccc(S(=O)(=O)NCC(=O)OCC(=O)c2cccs2)cc1
(d) C/C(=N/NC(=O)CNC(=O)C(c1ccccc1)c1ccccc1)c1ccco1
Answer: b. COC(=O)c1cc(S(=O)(=O)NCC2CCN(CCc3ccc(OC)cc3)CC2)cn1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1cc(S(=O)(=O)NCC2CCN(CCc3ccc(OC)cc3)CC2)cn1C
COC(=O)c1cc(S(=O)(=O)NCC2CCN(CCc3ccc(OC)cc3)CC2)cn1C
methyl 4-[[1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl]methylsulfamoyl]-1-methylpyrrole-2-carboxylate