Problem statement: Answer the multiple choice question.
Question: Which drug has a 12.185\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] Cl.O=C(CN1CCOCC1)NC1C2CC3CC(C2)CC1C3
[b] CC(C)(C)c1ccc2c(c1)N(CC(=O)N1CCOCC1)C(=O)CO2
[c] CCOC(=O)N1CCN(C(=O)COc2ccc3c(c2)C(=O)CC(C)(C)O3)CC1
[d] COc1ccc(CNc2nc(SC)n[nH]2)cc1OC
[e] CC(=O)c1ccc(OCCCC(=O)Nc2ccc3c(c2)OCCO3)cc1
Answer: c. CCOC(=O)N1CCN(C(=O)COc2ccc3c(c2)C(=O)CC(C)(C)O3)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(C(=O)COc2ccc3c(c2)C(=O)CC(C)(C)O3)CC1
CCOC(=O)N1CCN(C(=O)COc2ccc3c(c2)C(=O)CC(C)(C)O3)CC1
ethyl 4-[2-[(2,2-dimethyl-4-oxo-3H-chromen-6-yl)oxy]acetyl]piperazine-1-carboxylate