Problem statement: Answer the MCQ question.
Question: Which compound has a 13.122\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COC(=O)C1=C(C)Nc2c(c(=O)n(C)c(=O)n2C)C1c1cccc(O)c1
[b] CCOc1ccc(N/C(=N/c2nc(C)cc(C)n2)NC(=O)CC)cc1
[c] CCC1(CC)N=C(c2ccccc2)C(=S)N1
[d] CC(=O)Nc1ccc(-c2nnn(CC(=O)Nc3ccc4c(c3)OCO4)n2)cc1Cl
[e] COc1ccc(N2C(=O)C(Cl)=C(Nc3ccccc3O)C2=O)cc1
Answer: a. COC(=O)C1=C(C)Nc2c(c(=O)n(C)c(=O)n2C)C1c1cccc(O)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C1=C(C)Nc2c(c(=O)n(C)c(=O)n2C)C1c1cccc(O)c1
COC(=O)C1=C(C)Nc2c(c(=O)n(C)c(=O)n2C)C1c1cccc(O)c1
methyl 5-(3-hydroxyphenyl)-1,3,7-trimethyl-2,4-dioxo-5,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylate