Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -0.171\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCn1c(-c2ccncc2)n[nH]c1=S
b) O=C(Nc1ccnn1C1CCN(C(=O)c2ccc(Cl)cc2)CC1)C1CC1
c) COc1ccc(N2CCN(C(CNC(=O)C(=O)NCc3ccncc3)c3ccco3)CC2)cc1
d) N#Cc1ccc(CSc2nnc(-c3ccncc3)o2)cc1
e) COc1cccc(NC(=O)C2CCN(S(=O)(=O)c3ccc4c(c3)C(C)(C)C(=O)N4C)CC2)c1
Answer: c. COc1ccc(N2CCN(C(CNC(=O)C(=O)NCc3ccncc3)c3ccco3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(C(CNC(=O)C(=O)NCc3ccncc3)c3ccco3)CC2)cc1
COc1ccc(N2CCN(C(CNC(=O)C(=O)NCc3ccncc3)c3ccco3)CC2)cc1
N'-[2-(furan-2-yl)-2-[4-(4-methoxyphenyl)piperazin-1-yl]ethyl]-N-(pyridin-4-ylmethyl)oxamide