Problem statement: Answer the MCQ question.
Question: Which compound has a 10.273\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
(a) COC(=O)c1cc(C(=O)OCC(=O)NC2CCS(=O)(=O)C2)cc([N+](=O)[O-])c1
(b) Cc1cccc(NC(=O)c2sc3nc(N4CCOCC4)c4c(c3c2N)CCCC4)c1
(c) COc1ccc(N2CCN(C(=O)C3CCCN3S(=O)(=O)c3cccc4nsnc34)CC2)cc1
(d) C/C(CC(C)(C)c1ccccc1)=N\NS(=O)(=O)c1ccccc1
Answer: c. COc1ccc(N2CCN(C(=O)C3CCCN3S(=O)(=O)c3cccc4nsnc34)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(C(=O)C3CCCN3S(=O)(=O)c3cccc4nsnc34)CC2)cc1
COc1ccc(N2CCN(C(=O)C3CCCN3S(=O)(=O)c3cccc4nsnc34)CC2)cc1
[1-(2,1,3-benzothiadiazol-4-ylsulfonyl)pyrrolidin-2-yl]-[4-(4-methoxyphenyl)piperazin-1-yl]methanone