Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -11.683\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C(NCCc1c[nH]c2ccccc12)C(=O)NCC(c1ccco1)N1CCN(c2ccccc2)CC1
b) CC(=O)N1N=C2c3ccccc3CCC2C1c1cccs1
c) O=C(NCc1ccco1)c1cc(S(=O)(=O)N2CCCCC2)ccc1Cl
d) COc1cc(NS(=O)(=O)c2cccc3nsnc23)cc(OC)c1
e) COc1cc2c(C(=O)N3CCN(c4ccccc4F)CC3)cn(C)c(=O)c2cc1OC
Answer: c. O=C(NCc1ccco1)c1cc(S(=O)(=O)N2CCCCC2)ccc1Cl
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(NCc1ccco1)c1cc(S(=O)(=O)N2CCCCC2)ccc1Cl
O=C(NCc1ccco1)c1cc(S(=O)(=O)N2CCCCC2)ccc1Cl
2-chloro-N-(furan-2-ylmethyl)-5-piperidin-1-ylsulfonylbenzamide