Problem statement: Answer the multiple choice question.
Query: Which compound has a -22.847\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. Cc1onc(-c2ccccc2)c1C(=O)Nc1sc2c(c1C(N)=O)CCC2
b. CC(C)C[C@@H]1NC(=O)[C@H](C(C)C)NC(=O)c2cc([N+](=O)[O-])cc(I)c2OCC[C@@H](C(N)=O)NC1=O
c. COc1cc(CC(=O)OCn2nnc3ccccc3c2=O)cc(OC)c1OC
d. Cc1ccc(-c2csc3ncnc(N4CCN(C(=O)c5ccco5)CC4)c23)cc1
Answer: d. Cc1ccc(-c2csc3ncnc(N4CCN(C(=O)c5ccco5)CC4)c23)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(-c2csc3ncnc(N4CCN(C(=O)c5ccco5)CC4)c23)cc1
Cc1ccc(-c2csc3ncnc(N4CCN(C(=O)c5ccco5)CC4)c23)cc1
furan-2-yl-[4-[5-(4-methylphenyl)thieno[2,3-d]pyrimidin-4-yl]piperazin-1-yl]methanone