Problem statement: Answer the multiple-choice question.
Query: Which drug has a 2.255\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) COc1ccccc1C(=O)NCC(=O)NC(C)c1ccc(-n2ccnc2)cc1
b) CCc1nnc(SCC(=O)Nc2ccccc2)n1CC1CCCO1
c) COC(=O)c1ccc(OC(=O)CCN2C(=O)C3CCCCC3C2=O)cc1
d) COc1cc(/C=C/C(=O)OCC(=O)N2CC(=O)Nc3ccccc32)ccc1O
e) O=C(c1cc(-c2ccc(Cl)cc2)n(-c2ccc(Cl)cc2Cl)n1)N1CCOCC1
Answer: c. COC(=O)c1ccc(OC(=O)CCN2C(=O)C3CCCCC3C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1ccc(OC(=O)CCN2C(=O)C3CCCCC3C2=O)cc1
COC(=O)c1ccc(OC(=O)CCN2C(=O)C3CCCCC3C2=O)cc1
methyl 4-[3-(1,3-dioxo-3a,4,5,6,7,7a-hexahydroisoindol-2-yl)propanoyloxy]benzoate