Problem statement: Answer the multiple choice question.
Query: Which compound exhibits a -3.080\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1cccc2sc(N3CCN(C(=O)C4COc5ccccc5O4)CC3)nc12
b) O=c1[nH]c(Cc2cccs2)nc2scc(-c3ccc(Cl)cc3)c12
c) C1=CCC(CN2CCNCC2)CC1.O=C(O)C(F)(F)F
d) COc1ccc(CNC(=O)C(C)NCc2ccc(S(N)(=O)=O)cc2)cc1
e) CCCc1nc2c([nH]1)C(c1cccnc1)C(C#N)=C(N)O2
Answer: b. O=c1[nH]c(Cc2cccs2)nc2scc(-c3ccc(Cl)cc3)c12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=c1[nH]c(Cc2cccs2)nc2scc(-c3ccc(Cl)cc3)c12
O=c1[nH]c(Cc2cccs2)nc2scc(-c3ccc(Cl)cc3)c12
5-(4-chlorophenyl)-2-(thiophen-2-ylmethyl)-3H-thieno[2,3-d]pyrimidin-4-one