Problem statement: Answer the MCQ question.
Query: Which drug has a 11.405\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CC(=O)Nc1ccc(S(=O)(=O)NCCC(=O)OCC(=O)c2ccc(Br)cc2)cc1
(b) COc1cccc(CNC(=O)c2ccc(NC(=O)CC3SC(N4CCCCC4)=NC3=O)cc2)c1
(c) CCCOc1ccc(N2C(=O)CC(SCCc3nc4ccccc4[nH]3)C2=O)cc1
(d) CC#CC(=O)N1CCC(C(=O)Nc2ccc(Oc3ccccc3)nc2)CC1
(e) CCc1ccccc1NC(=O)CSc1nc2[nH]c(=O)cc(O)c2s1
Answer: d. CC#CC(=O)N1CCC(C(=O)Nc2ccc(Oc3ccccc3)nc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC#CC(=O)N1CCC(C(=O)Nc2ccc(Oc3ccccc3)nc2)CC1
CC#CC(=O)N1CCC(C(=O)Nc2ccc(Oc3ccccc3)nc2)CC1
1-but-2-ynoyl-N-(6-phenoxypyridin-3-yl)piperidine-4-carboxamide