Task: Answer the multiple choice question.
Query: Which compound exhibits a -12.688\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1ccc(CNC(=O)C(C)N2CCN(c3ccc(C(C)=O)cc3)CC2)cc1
b CC1(C)OC(=O)C(=C2CCCN2)C(=O)O1
c COc1ccc2ccc(O)c(CN(C)CC(=O)Nc3ccccc3C(F)(F)F)c2c1
d CCOc1cccc(-c2c(C(=O)N/N=C/c3cccnc3)nnn2-c2nonc2N)c1
e O=C(NCc1ccccn1)c1ccc(CS(=O)(=O)Cc2ccc(Cl)cc2)o1
Answer: a. COc1ccc(CNC(=O)C(C)N2CCN(c3ccc(C(C)=O)cc3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C(C)N2CCN(c3ccc(C(C)=O)cc3)CC2)cc1
COc1ccc(CNC(=O)C(C)N2CCN(c3ccc(C(C)=O)cc3)CC2)cc1
2-[4-(4-acetylphenyl)piperazin-1-yl]-N-[(4-methoxyphenyl)methyl]propanamide