Problem statement: Answer the MCQ question.
Query: Which compound has a -2.875\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
[a] COCc1nc(-c2ccc(-c3ccc(OC)cc3)nc2OC)no1
[b] C/C(=N\NC(=O)c1ccccc1)c1ccc(C)c([N+](=O)[O-])c1
[c] COc1ccc(S(=O)(=O)N2CCN(C(=O)CN3C(=O)NC(C)(c4ccc5ccccc5c4)C3=O)CC2)cc1
[d] Cc1ccc(NC(=O)c2ccc(S(=O)(=O)NCc3cccnc3)cc2)c(C)c1
Answer: c. COc1ccc(S(=O)(=O)N2CCN(C(=O)CN3C(=O)NC(C)(c4ccc5ccccc5c4)C3=O)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(S(=O)(=O)N2CCN(C(=O)CN3C(=O)NC(C)(c4ccc5ccccc5c4)C3=O)CC2)cc1
COc1ccc(S(=O)(=O)N2CCN(C(=O)CN3C(=O)NC(C)(c4ccc5ccccc5c4)C3=O)CC2)cc1
3-[2-[4-(4-methoxyphenyl)sulfonylpiperazin-1-yl]-2-oxoethyl]-5-methyl-5-naphthalen-2-ylimidazolidine-2,4-dione