Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a -30.857\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CCO[C@@H]1OC(C(=O)NC2CC2)=C[C@H](C)[C@H]1CCCO
b.) O=C(Cn1cnc2ccccc21)OCC(=O)N1CCc2ccccc2C1
c.) O=C1c2ccccc2C2(c3ccccc3)N1CCN2C(=O)C(Cl)(Cl)Cl
d.) Cc1cccn2c(=O)nc(SCC(=O)N3CCN(c4ccccc4)CC3)nc12
e.) O=C1C2C3CC(C2C(=O)N1c1cccc(Cl)c1)[C@H](O)C3O
Answer: d. Cc1cccn2c(=O)nc(SCC(=O)N3CCN(c4ccccc4)CC3)nc12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1cccn2c(=O)nc(SCC(=O)N3CCN(c4ccccc4)CC3)nc12
Cc1cccn2c(=O)nc(SCC(=O)N3CCN(c4ccccc4)CC3)nc12
9-methyl-2-[2-oxo-2-(4-phenylpiperazin-1-yl)ethyl]sulfanylpyrido[1,2-a][1,3,5]triazin-4-one