Problem statement: Answer the multiple-choice question.
Query: Which drug has a -22.257\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCCCCC(=O)N1CC2(CC(c3cccc(NC(=O)COc4ccc(Cl)cc4)c3)=NO2)C[C@@H]1C(N)=O
(b) COc1ccc(C(=O)N2CCC(C(=O)O)CC2)c2ccccc12
(c) CC(C)c1ccc(/C=C(\c2nc3ccccc3[nH]2)S(=O)(=O)c2ccccc2)cc1
(d) CCn1cc(CCC(=O)NCCN2CCOCC2)c2ccccc21
(e) Cc1cc(S(=O)(=O)NCC(c2ccc(F)cc2)N2CCN(C)CC2)ccc1F
Answer: a. CCCCCC(=O)N1CC2(CC(c3cccc(NC(=O)COc4ccc(Cl)cc4)c3)=NO2)C[C@@H]1C(N)=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCCCC(=O)N1CC2(CC(c3cccc(NC(=O)COc4ccc(Cl)cc4)c3)=NO2)C[C@@H]1C(N)=O
CCCCCC(=O)N1CC2(CC(c3cccc(NC(=O)COc4ccc(Cl)cc4)c3)=NO2)C[C@@H]1C(N)=O
(8R)-3-[3-[[2-(4-chlorophenoxy)acetyl]amino]phenyl]-7-hexanoyl-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide