Problem statement: Answer the multiple-choice question.
Query: Which drug has a 27.102\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CS(=O)(=O)N(CC(=O)NCc1ccncc1)c1cc(Cl)cc(Cl)c1
b: CC1CC(C)CN(S(=O)(=O)c2cccc(C(=O)N3C(=O)c4cccc(N)c4C3=O)c2)C1
c: COc1ccc(S(N)(=O)=O)cc1C(=O)NCCCN1CCN(c2ccccc2OC)CC1.CS(=O)(=O)O
d: COc1ccc(C(=O)CCC(=O)N2CCN(c3ccc(C)cc3)C(C)C2)cc1
e: CCCCn1c(N)c(N(C)C(=O)c2cc3c(s2)CCCCC3)c(=O)[nH]c1=O
Answer: d. COc1ccc(C(=O)CCC(=O)N2CCN(c3ccc(C)cc3)C(C)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)CCC(=O)N2CCN(c3ccc(C)cc3)C(C)C2)cc1
COc1ccc(C(=O)CCC(=O)N2CCN(c3ccc(C)cc3)C(C)C2)cc1
1-(4-methoxyphenyl)-4-[3-methyl-4-(4-methylphenyl)piperazin-1-yl]butane-1,4-dione