Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -3.283\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. Cc1ccc(S(=O)(=O)N/N=C/c2ccc(OC3CSC3)cc2)cc1
b. COc1ccc([C@H]2CC(=O)C=C(c3ccccc3)C2)cc1OC
c. COc1ccc(C2SCC(=O)N2CC23CC4CC(CC(C4)C2)C3)cc1
d. COc1ccc(/C=C/S(=O)(=O)NCc2ccccc2)cc1OC
e. COc1ccc(/C=C/C(=O)N2CCN(c3ccccc3)CC2)cc1S(=O)(=O)N1CCOCC1
Answer: b. COc1ccc([C@H]2CC(=O)C=C(c3ccccc3)C2)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc([C@H]2CC(=O)C=C(c3ccccc3)C2)cc1OC
COc1ccc([C@H]2CC(=O)C=C(c3ccccc3)C2)cc1OC
(5R)-5-(3,4-dimethoxyphenyl)-3-phenylcyclohex-2-en-1-one