Problem statement: Answer the multiple-choice question.
Question: Which drug has a 16.277\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] Cc1cc(C)n(-c2nc(SCCN(C)C)c3c4c(sc3n2)COC(C)(C)C4)n1
[b] COc1cccc(C(=O)Nc2ccc3[nH]ncc3c2)c1OC
[c] O=C(CNC(=O)COc1ccccc1)NCCN1CCOCC1
[d] COc1ccc(NC(=O)C2CC3CCC2C3)c(OC)c1
[e] CCOC(=O)/C(C#N)=C/c1c(N2CCCCCC2)nc2ccccn2c1=O
Answer: e. CCOC(=O)/C(C#N)=C/c1c(N2CCCCCC2)nc2ccccn2c1=O
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)/C(C#N)=C/c1c(N2CCCCCC2)nc2ccccn2c1=O
CCOC(=O)/C(C#N)=C/c1c(N2CCCCCC2)nc2ccccn2c1=O
ethyl (E)-3-[2-(azepan-1-yl)-4-oxopyrido[1,2-a]pyrimidin-3-yl]-2-cyanoprop-2-enoate