Problem statement: Answer the multiple-choice question.
Question: Which compound exhibits a 11.326\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: COc1ccc(NC(=O)C2CCN(C(=O)c3cccs3)CC2)cc1
b: O=C([C@@H]1CC=C[C@@H]2CCN(C3CC3)C(=O)[C@@H]21)N1CCN(c2ccccc2)CC1
c: O=C(CCc1ccccc1)NCC1OCCc2ccccc21
d: CCCCCOc1ccc(N2C(=O)CC(N(O)c3ccccc3)C2=O)cc1
Answer: b. O=C([C@@H]1CC=C[C@@H]2CCN(C3CC3)C(=O)[C@@H]21)N1CCN(c2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C([C@@H]1CC=C[C@@H]2CCN(C3CC3)C(=O)[C@@H]21)N1CCN(c2ccccc2)CC1
O=C([C@@H]1CC=C[C@@H]2CCN(C3CC3)C(=O)[C@@H]21)N1CCN(c2ccccc2)CC1
(4aS,8R,8aS)-2-cyclopropyl-8-(4-phenylpiperazine-1-carbonyl)-3,4,4a,7,8,8a-hexahydroisoquinolin-1-one