Problem statement: Answer the multiple-choice question.
Question: Which drug has a 5.933\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) COc1ccc(NC(=O)CN2CCN(S(=O)(=O)c3ccc(Br)cc3)CC2)c(OC)c1
b.) Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)n1nnc2ccccc21
c.) CCOc1ccccc1-c1nc(CN2CCC(C(=O)N3CCOCC3)CC2)c(C)o1
d.) CC(C)(C)OC(=O)CN1C(=O)NC(Cc2c[nH]c3ccccc23)C1=O
e.) CC(C)=CCc1c([C@@H]2CCc3ccc(O)cc3O2)cc2c(c1O)OC(C)(C)C=C2
Answer: c. CCOc1ccccc1-c1nc(CN2CCC(C(=O)N3CCOCC3)CC2)c(C)o1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccccc1-c1nc(CN2CCC(C(=O)N3CCOCC3)CC2)c(C)o1
CCOc1ccccc1-c1nc(CN2CCC(C(=O)N3CCOCC3)CC2)c(C)o1
[1-[[2-(2-ethoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methyl]piperidin-4-yl]-morpholin-4-ylmethanone