Problem statement: Answer the multiple-choice question.
Question: Which drug has a 18.213\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1ccc(C)c(C(=O)CN2C(=O)NC3(CCc4ccccc43)C2=O)c1
b) Cc1cccc(NC(=S)N(C)C)c1C
c) COc1ccccc1N(C(=O)c1snc(C(N)=O)c1N)C(C(=O)NC1CCCC1)c1ccco1
d) O=C(Cc1ccccc1)NCC(=O)OC(c1ccccc1)c1ccccc1
e) COc1ccc(CNC(=O)C2CCN(S(=O)(=O)c3ccccc3)CC2)cc1
Answer: e. COc1ccc(CNC(=O)C2CCN(S(=O)(=O)c3ccccc3)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CNC(=O)C2CCN(S(=O)(=O)c3ccccc3)CC2)cc1
COc1ccc(CNC(=O)C2CCN(S(=O)(=O)c3ccccc3)CC2)cc1
1-(benzenesulfonyl)-N-[(4-methoxyphenyl)methyl]piperidine-4-carboxamide