Problem statement: Answer the multiple choice question.
Question: Which drug has a -47.435\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] Cc1ccc(N2CC(C(=O)N3CCC4(CC3)CC(=O)c3ccccc3O4)CC2=O)cc1
[b] COc1cccc(N2CCN(C(=O)CCCCCn3c(=S)[nH]c4cc5c(cc4c3=O)OCO5)CC2)c1
[c] CC(=O)c1ccc(N2Cc3ccccc3/C2=N\C(=O)Nc2ccc(Cl)cc2)cc1
[d] CC(C)c1ccc(NC(=O)c2ccc3c(c2)CCN3S(C)(=O)=O)cc1
[e] O=C(Cc1ccccc1)NNC(=O)c1ccc(NC(=O)c2ccccc2)cc1
Answer: a. Cc1ccc(N2CC(C(=O)N3CCC4(CC3)CC(=O)c3ccccc3O4)CC2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(N2CC(C(=O)N3CCC4(CC3)CC(=O)c3ccccc3O4)CC2=O)cc1
Cc1ccc(N2CC(C(=O)N3CCC4(CC3)CC(=O)c3ccccc3O4)CC2=O)cc1
1'-[1-(4-methylphenyl)-5-oxopyrrolidine-3-carbonyl]spiro[3H-chromene-2,4'-piperidine]-4-one