Problem statement: Answer the MCQ question.
Question: Which drug has a -4.434\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) O=C(c1cccnc1)N1CCN(c2ccc(Cl)cc2)CC1
b.) CC1Cc2ccccc2N1C(=O)CO/N=C/c1ccc(OC(F)F)cc1
c.) CCOC(=O)c1nn(-c2ccccc2)c(C#N)c1N
d.) c1ccc(OCCCn2nnc(-c3cccnc3)n2)cc1
e.) C[C@]12CC[C@@H]3c4ccc(OS(=O)(=O)[O-])cc4CC[C@H]3[C@@H]1CCC2=O.[Na+]
Answer: a. O=C(c1cccnc1)N1CCN(c2ccc(Cl)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1cccnc1)N1CCN(c2ccc(Cl)cc2)CC1
O=C(c1cccnc1)N1CCN(c2ccc(Cl)cc2)CC1
[4-(4-chlorophenyl)piperazin-1-yl]-pyridin-3-ylmethanone