Problem statement: Answer the MCQ question.
Question: Which drug has a 8.559\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCOc3cc(C)ccc3C)CC2)cc1
b) O=C(/C=C/c1ccco1)NC(=S)Nc1ccc(Cl)cn1
c) N#CC1=C(N)Oc2c(c(=O)oc3ccccc23)C1c1ccncc1
d) Cc1ccc(NS(=O)(=O)c2cccc([N+](=O)[O-])c2)nc1
e) COc1ccc(-c2cc(=O)oc3cc(OCC(=O)NCc4ccccn4)ccc23)cc1
Answer: b. O=C(/C=C/c1ccco1)NC(=S)Nc1ccc(Cl)cn1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(/C=C/c1ccco1)NC(=S)Nc1ccc(Cl)cn1
O=C(/C=C/c1ccco1)NC(=S)Nc1ccc(Cl)cn1
(E)-N-[(5-chloropyridin-2-yl)carbamothioyl]-3-(furan-2-yl)prop-2-enamide