Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 10.895\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CN(c1ncc(C(F)(F)F)cc1Cl)N1C(=O)c2cccc([N+](=O)[O-])c2C1=O
(b) COc1ccc([C@H]2CC(=O)C=C(c3ccc(F)cc3OCc3ccccc3)C2)cc1
(c) Cc1ccc(C(=O)OCC(=O)N(CC(C)C)c2c(N)n(Cc3ccccc3)c(=O)[nH]c2=O)cc1[N+](=O)[O-]
(d) CN(CC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C(=O)c1cc(-c2ccncc2)nc2ccccc12
(e) CCc1nc(Sc2nc(C)cc(C)n2)c2oc3ccccc3c2n1
Answer: d. CN(CC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C(=O)c1cc(-c2ccncc2)nc2ccccc12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN(CC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C(=O)c1cc(-c2ccncc2)nc2ccccc12
CN(CC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)C(=O)c1cc(-c2ccncc2)nc2ccccc12
N-[2-[4-chloro-3-(trifluoromethyl)anilino]-2-oxoethyl]-N-methyl-2-pyridin-4-ylquinoline-4-carboxamide