Problem statement: Answer the multiple-choice question.
Question: Which compound has a -16.615\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a: O=C(c1ccc(Cl)cc1)c1cc([N+](=O)[O-])ccc1N1CCOCC1
b: COc1ccccc1OCC(=O)NCC1CCCN(C(=O)c2ccccc2SC)C1
c: COc1ccc2c(c1)[nH]c1c(=O)n(/N=C/c3ccc(OC)c(CN4CCCCC4)c3)cnc12
d: O=C(CN1CCC(C(=O)c2ccc(F)cc2)CC1)NCc1ccccc1F
e: COc1ccc(NC(=S)N/N=C2/CCCc3c(C)cc(C)cc32)cc1
Answer: c. COc1ccc2c(c1)[nH]c1c(=O)n(/N=C/c3ccc(OC)c(CN4CCCCC4)c3)cnc12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2c(c1)[nH]c1c(=O)n(/N=C/c3ccc(OC)c(CN4CCCCC4)c3)cnc12
COc1ccc2c(c1)[nH]c1c(=O)n(/N=C/c3ccc(OC)c(CN4CCCCC4)c3)cnc12
7-methoxy-3-[(E)-[4-methoxy-3-(piperidin-1-ylmethyl)phenyl]methylideneamino]-5H-pyrimido[5,4-b]indol-4-one