Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a -3.602\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: CC(C)(C)c1cc(Br)c(O)c(N=Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)c1
b: Cc1ccc(CN(c2ccc(C(=O)Nc3ccc4c(c3)OCO4)cc2)S(C)(=O)=O)cc1
c: COc1ccc(C(=O)NC(C(=O)N2CCc3ccccc32)C(C)C)cc1
d: O=C(C1CCC(CNS(=O)(=O)c2cccs2)CC1)N1CCN(c2ccc(F)cc2)CC1
e: C/C(=N\NC(=O)c1nnn(-c2nonc2N)c1-c1cccs1)c1ccc(C)cc1
Answer: e. C/C(=N\NC(=O)c1nnn(-c2nonc2N)c1-c1cccs1)c1ccc(C)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
C/C(=N\NC(=O)c1nnn(-c2nonc2N)c1-c1cccs1)c1ccc(C)cc1
C/C(=N\NC(=O)c1nnn(-c2nonc2N)c1-c1cccs1)c1ccc(C)cc1
1-(4-amino-1,2,5-oxadiazol-3-yl)-N-[(E)-1-(4-methylphenyl)ethylideneamino]-5-thiophen-2-yltriazole-4-carboxamide