Problem statement: Answer the multiple choice question.
Question: Which compound exhibits a 11.265\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) COc1ccc(S(=O)(=O)N(CC(=O)Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)Cc2ccc(F)cc2)cc1
b.) COc1ccc(C2=NO[C@@H]3[C@@H]4C[C@@H]([C@H]5C(=O)N(C)C(=O)[C@@H]45)[C@H]23)c(OC)c1
c.) O=S(=O)(F)c1ccc2nc(-c3cccc(Sc4ccccc4)c3)cc(Cl)c2c1
d.) COC(=O)C[C@H]1c2cc(F)ccc2S(=O)(=O)N1c1ccccc1
e.) CCCC(/C=C/c1ccc(OC(C)=O)cc1)=C1/c2ccccc2C(=O)N1c1ccccc1
Answer: e. CCCC(/C=C/c1ccc(OC(C)=O)cc1)=C1/c2ccccc2C(=O)N1c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCC(/C=C/c1ccc(OC(C)=O)cc1)=C1/c2ccccc2C(=O)N1c1ccccc1
CCCC(/C=C/c1ccc(OC(C)=O)cc1)=C1/c2ccccc2C(=O)N1c1ccccc1
[4-[(E,3E)-3-(3-oxo-2-phenylisoindol-1-ylidene)hex-1-enyl]phenyl] acetate