Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -5.232\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a C#CCOCCOCCOCCNc1nc(N2CCN(C(=O)C([C@@H](C)CC)n3cc(C(N)COC(=O)C(F)(F)F)nn3)CC2)nc(N2CCN(C(=O)[C@H](CCCCN)n3cc(C(N)CC(C)C)nn3)CC2)n1.Cl
b CCOc1ccc(CCNC(=O)C(C)n2nc(C)c3c(C)n(-c4ccccc4)nc3c2=O)cc1
c O=C(O)c1ccccc1SCc1csc(-c2ccccc2)n1
d Cn1c(=O)[nH]c(=O)c2cc(C(=O)c3cc(F)ccc3O)cnc21
e COc1n[nH]c(C(=O)Nc2nc3ccccc3s2)c1[N+](=O)[O-]
Answer: b. CCOc1ccc(CCNC(=O)C(C)n2nc(C)c3c(C)n(-c4ccccc4)nc3c2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOc1ccc(CCNC(=O)C(C)n2nc(C)c3c(C)n(-c4ccccc4)nc3c2=O)cc1
CCOc1ccc(CCNC(=O)C(C)n2nc(C)c3c(C)n(-c4ccccc4)nc3c2=O)cc1
2-(3,4-dimethyl-7-oxo-2-phenylpyrazolo[3,4-d]pyridazin-6-yl)-N-[2-(4-ethoxyphenyl)ethyl]propanamide