Problem statement: Answer the MCQ question.
Question: Which drug has a 13.971\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) O=C(Nc1ccccc1C(=O)Nc1ccccn1)c1cccc([N+](=O)[O-])c1
b.) COc1ccc(C(C)=O)cc1COC(=O)c1ccc2c(c1)OCCO2
c.) NC(=O)CSc1nnc(-c2ccc([N+](=O)[O-])cc2)o1
d.) COC(=O)C[C@H]1c2ccccc2S(=O)(=O)N1Cc1ccc(OC)cc1
e.) CCN1CCN(C(=O)/C=C/c2ccc(OC)c(OC)c2)CC1
Answer: d. COC(=O)C[C@H]1c2ccccc2S(=O)(=O)N1Cc1ccc(OC)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)C[C@H]1c2ccccc2S(=O)(=O)N1Cc1ccc(OC)cc1
COC(=O)C[C@H]1c2ccccc2S(=O)(=O)N1Cc1ccc(OC)cc1
methyl 2-[(3S)-2-[(4-methoxyphenyl)methyl]-1,1-dioxo-3H-1,2-benzothiazol-3-yl]acetate