Problem statement: Answer the MCQ question.
Question: Which drug exhibits a 19.800\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCOC(=O)c1c(C)[nH]c(C)c1S(=O)(=O)N1CCN(C(=O)c2ccco2)CC1
b) CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
c) COc1ccc(C)cc1N(CC(=O)NCCN1CCOCC1)S(=O)(=O)c1ccccc1
d) CSCCC(NC(=O)OC(C)(C)C)C(=O)Oc1ccc2c(=O)c(-c3ccc4c(c3)OCCO4)coc2c1
e) O=C(O)c1ccc(N=Nc2c(O)[nH]c3cc(Cl)ccc23)cc1
Answer: a. CCOC(=O)c1c(C)[nH]c(C)c1S(=O)(=O)N1CCN(C(=O)c2ccco2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)c1c(C)[nH]c(C)c1S(=O)(=O)N1CCN(C(=O)c2ccco2)CC1
CCOC(=O)c1c(C)[nH]c(C)c1S(=O)(=O)N1CCN(C(=O)c2ccco2)CC1
ethyl 4-[4-(furan-2-carbonyl)piperazin-1-yl]sulfonyl-2,5-dimethyl-1H-pyrrole-3-carboxylate