Problem statement: Answer the multiple-choice question.
Query: Which drug has a -24.826\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COC(=O)Nc1ccc2c(c1)N(C(=O)CCN1CCOCC1)c1ccccc1S2.Cl
b COc1cccc(C(=O)Nc2cccnc2)c1
c COc1cc(C(=O)NC(C)c2cnn(-c3ccccc3C)c2C)cc(OC)c1OC
d COc1ccc(N2C(=O)CC(NC34CC5CC(CC(C5)C3)C4)C2=O)c(OC)c1
e CCSc1nnc(NC(=O)Cn2cnc3ccccc3c2=O)s1
Answer: c. COc1cc(C(=O)NC(C)c2cnn(-c3ccccc3C)c2C)cc(OC)c1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(C(=O)NC(C)c2cnn(-c3ccccc3C)c2C)cc(OC)c1OC
COc1cc(C(=O)NC(C)c2cnn(-c3ccccc3C)c2C)cc(OC)c1OC
3,4,5-trimethoxy-N-[1-[5-methyl-1-(2-methylphenyl)pyrazol-4-yl]ethyl]benzamide