Task: Answer the MCQ question.
Question: Which drug has a 3.449\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) Cc1onc(-c2ccccc2)c1-c1csc(N/N=C/c2ccccc2Cl)n1
b.) CC1CCN(C(=S)Nc2ccc3nc4n(c(=O)c3c2)CCCCC4)CC1
c.) COc1ccc(C(=O)N2CC3(CC(c4cccc(NC(=O)COc5ccc(Cl)cc5)c4)=NO3)C[C@@H]2C(N)=O)cc1
d.) CN(c1ccccc1C(=O)Nc1cccc(Br)c1)S(=O)(=O)c1ccccc1
Answer: c. COc1ccc(C(=O)N2CC3(CC(c4cccc(NC(=O)COc5ccc(Cl)cc5)c4)=NO3)C[C@@H]2C(N)=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(=O)N2CC3(CC(c4cccc(NC(=O)COc5ccc(Cl)cc5)c4)=NO3)C[C@@H]2C(N)=O)cc1
COc1ccc(C(=O)N2CC3(CC(c4cccc(NC(=O)COc5ccc(Cl)cc5)c4)=NO3)C[C@@H]2C(N)=O)cc1
(8R)-3-[3-[[2-(4-chlorophenoxy)acetyl]amino]phenyl]-7-(4-methoxybenzoyl)-1-oxa-2,7-diazaspiro[4.4]non-2-ene-8-carboxamide