Problem statement: Answer the multiple choice question.
Query: Which drug exhibits a -8.482\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) CCCn1c(SCC(=O)NCc2ccco2)nc2c1c(=O)n(C)c(=O)n2C
b) CCC1CCc2sc(C(=O)NCC(c3ccccc3OC)N3CCCC3)cc2C1
c) Cc1ccc(Cn2nnnc2CN2CCC(NC(=O)c3ccccc3F)CC2)cc1
d) O=C1C(Cl)=C(NCCCN2CCOCC2)C(=O)N1CCc1ccccc1
e) CCOC(=O)C1=C(C)Nc2ncnn2C1c1ccc2c(c1)OCO2
Answer: c. Cc1ccc(Cn2nnnc2CN2CCC(NC(=O)c3ccccc3F)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(Cn2nnnc2CN2CCC(NC(=O)c3ccccc3F)CC2)cc1
Cc1ccc(Cn2nnnc2CN2CCC(NC(=O)c3ccccc3F)CC2)cc1
2-fluoro-N-[1-[[1-[(4-methylphenyl)methyl]tetrazol-5-yl]methyl]piperidin-4-yl]benzamide