Problem statement: Answer the multiple choice question.
Question: Which drug exhibits a -18.951\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) O=C(c1cc(N2C(=O)C3C4CCC(C4)C3C2=O)ccc1Cl)N1CCN(c2ccc(F)cc2)CC1
b.) COc1ccc(-c2c(=O)n(OCc3ccccn3)c3ccccc3[n+]2[O-])cc1OC
c.) CCCC(=O)Nc1ccc(-c2cnc(-c3ccc(NC(=O)CCC)cc3)nc2)cc1
d.) CC(C)NC(=O)Nc1ccc(Br)cc1Cl
Answer: a. O=C(c1cc(N2C(=O)C3C4CCC(C4)C3C2=O)ccc1Cl)N1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1cc(N2C(=O)C3C4CCC(C4)C3C2=O)ccc1Cl)N1CCN(c2ccc(F)cc2)CC1
O=C(c1cc(N2C(=O)C3C4CCC(C4)C3C2=O)ccc1Cl)N1CCN(c2ccc(F)cc2)CC1
4-[4-chloro-3-[4-(4-fluorophenyl)piperazine-1-carbonyl]phenyl]-4-azatricyclo[5.2.1.02,6]decane-3,5-dione