Problem statement: Answer the MCQ question.
Query: Which drug exhibits a 9.125\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) Cc1nc2c(C)cccn2c1/C(O)=C1\C(=O)C(=O)N(CCN(C)C)C1c1ccco1
b.) COc1ccc(CC(=O)Nc2cccc(C(=O)O)c2C)cc1
c.) CC(=O)Nc1cc(-c2nc3ccccc3o2)ccc1Cl
d.) COCc1cc(C)nc2sc(C(=O)NCCO)c(-n3cccc3)c12
e.) COC(=O)CC1(C(=O)OC)Oc2ccc(Br)cc2C(=O)N1c1cc(Cl)cc(Cl)c1
Answer: e. COC(=O)CC1(C(=O)OC)Oc2ccc(Br)cc2C(=O)N1c1cc(Cl)cc(Cl)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)CC1(C(=O)OC)Oc2ccc(Br)cc2C(=O)N1c1cc(Cl)cc(Cl)c1
COC(=O)CC1(C(=O)OC)Oc2ccc(Br)cc2C(=O)N1c1cc(Cl)cc(Cl)c1
methyl 6-bromo-3-(3,5-dichlorophenyl)-2-(2-methoxy-2-oxoethyl)-4-oxo-1,3-benzoxazine-2-carboxylate