Problem statement: Answer the MCQ question.
Query: Which drug has a 16.497\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1ccc(NC(C)=O)cc1NC(=O)CSc1nnc(-c2ccc(F)cc2)n1N
b. O=S(=O)(NC1CC1)c1ccc(Cl)cc1
c. COc1ccccc1NC(=S)NC(=O)/C=C/c1cccs1
d. COc1ccc2[nH]c(=O)c(C(c3nnnn3CC3CCCO3)N3CCCCC3)cc2c1
e. CCc1ccccc1N(CC(=O)NC(C)C)C(=O)CCC(=O)Nc1nccs1
Answer: d. COc1ccc2[nH]c(=O)c(C(c3nnnn3CC3CCCO3)N3CCCCC3)cc2c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2[nH]c(=O)c(C(c3nnnn3CC3CCCO3)N3CCCCC3)cc2c1
COc1ccc2[nH]c(=O)c(C(c3nnnn3CC3CCCO3)N3CCCCC3)cc2c1
6-methoxy-3-[[1-(oxolan-2-ylmethyl)tetrazol-5-yl]-piperidin-1-ylmethyl]-1H-quinolin-2-one