Problem statement: Answer the multiple-choice question.
Question: Which compound has a 21.782\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COC(=O)c1cc(S(=O)(=O)N2CCN(c3ccccc3OC)CC2)cn1C
[b] COc1ccc(CCNC(=O)CCS(=O)(=O)c2ccc(C)cc2)cc1OC
[c] COC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccc(C)o3)C2c2cc(OC)ccc2OC)nc1C
[d] CCCN(C(=O)COC(=O)CNC(=O)c1ccc2ccccc2c1)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O
[e] CCOC(=O)C1C(=O)NC(N2CCN(c3ccccc3)CC2)=NC1c1ccccc1
Answer: a. COC(=O)c1cc(S(=O)(=O)N2CCN(c3ccccc3OC)CC2)cn1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1cc(S(=O)(=O)N2CCN(c3ccccc3OC)CC2)cn1C
COC(=O)c1cc(S(=O)(=O)N2CCN(c3ccccc3OC)CC2)cn1C
methyl 4-[4-(2-methoxyphenyl)piperazin-1-yl]sulfonyl-1-methylpyrrole-2-carboxylate