Task: Answer the MCQ question.
Question: Which drug has a 13.291\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CCOc1ccc(N(CC(=O)NC2CCCC(C)C2C)S(=O)(=O)c2c(C)noc2C)cc1
[b] Cc1nnc(SCC(=O)NC(C)(C)C)n1NCc1c(F)cccc1Cl
[c] CC1(c2nnc(-c3ccc(Cl)cc3)o2)CC(c2cccnc2)=NO1
[d] COc1ccc2c(c1)OC[C@H]1[C@H]2N2C(=O)CN(CC3CCCO3)C(=O)[C@@]2(C)[C@H]1c1ccccc1
[e] CCN(CC(=O)NCc1ccc(F)cc1)C(=O)c1ccc(Cl)cc1
Answer: d. COc1ccc2c(c1)OC[C@H]1[C@H]2N2C(=O)CN(CC3CCCO3)C(=O)[C@@]2(C)[C@H]1c1ccccc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc2c(c1)OC[C@H]1[C@H]2N2C(=O)CN(CC3CCCO3)C(=O)[C@@]2(C)[C@H]1c1ccccc1
COc1ccc2c(c1)OC[C@H]1[C@H]2N2C(=O)CN(CC3CCCO3)C(=O)[C@@]2(C)[C@H]1c1ccccc1
(1R,10R,11R,12R)-5-methoxy-12-methyl-14-(oxolan-2-ylmethyl)-11-phenyl-8-oxa-14,17-diazatetracyclo[8.7.0.02,7.012,17]heptadeca-2(7),3,5-triene-13,16-dione