Problem statement: Answer the multiple-choice question.
Question: Which compound has a -5.402\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options:
a. c1ccc(-n2ncc3c(NCc4ccc5c(c4)OCO5)ncnc32)cc1
b. COc1ccc(C(CNC(=O)c2cc(S(=O)(=O)NCc3ccccc3)ccc2C)N2CCOCC2)cc1
c. COc1ccc2nc(NC(=O)CSc3cn[nH]n3)sc2c1
Answer: b. COc1ccc(C(CNC(=O)c2cc(S(=O)(=O)NCc3ccccc3)ccc2C)N2CCOCC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(C(CNC(=O)c2cc(S(=O)(=O)NCc3ccccc3)ccc2C)N2CCOCC2)cc1
COc1ccc(C(CNC(=O)c2cc(S(=O)(=O)NCc3ccccc3)ccc2C)N2CCOCC2)cc1
5-(benzylsulfamoyl)-N-[2-(4-methoxyphenyl)-2-morpholin-4-ylethyl]-2-methylbenzamide