Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 8.737\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a CCOC(=O)C1CN(S(=O)(=O)c2ccc(OC)cc2)c2ccccc2O1
b CN(C)c1cc(-c2ccc(Cl)cc2Cl)oc(=O)c1Cl
c COc1ccc(C(=O)Nc2cc(C(=O)c3ccccc3)c(C)oc2=O)cc1
d Cc1nonc1C1CCCN1C(=O)c1cc(COc2ccc(F)cc2Cl)on1
e Cc1ccc2c(c1)cc1c(=O)n(CC(=O)N(C)c3ccccc3)nc(C)n12
Answer: d. Cc1nonc1C1CCCN1C(=O)c1cc(COc2ccc(F)cc2Cl)on1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1nonc1C1CCCN1C(=O)c1cc(COc2ccc(F)cc2Cl)on1
Cc1nonc1C1CCCN1C(=O)c1cc(COc2ccc(F)cc2Cl)on1
[5-[(2-chloro-4-fluorophenoxy)methyl]-1,2-oxazol-3-yl]-[2-(4-methyl-1,2,5-oxadiazol-3-yl)pyrrolidin-1-yl]methanone