Problem statement: Answer the MCQ question.
Query: Which compound has a 22.244\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccc(/C=N/Nc2ncc(C(F)(F)F)cc2Cl)cc1OC
b) Cc1noc(NC(=O)c2ccc(Cl)cc2)c1Cl
c) COc1ccc([C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2)cc1O
d) CCOC(=O)C1CCCN(C(=O)COc2ccccc2O)C1
e) COc1ccc2oc(C(=O)OC/C(O)=C(\C#N)c3nc4ccccc4[nH]3)c(C)c2c1
Answer: a. COc1ccc(/C=N/Nc2ncc(C(F)(F)F)cc2Cl)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(/C=N/Nc2ncc(C(F)(F)F)cc2Cl)cc1OC
COc1ccc(/C=N/Nc2ncc(C(F)(F)F)cc2Cl)cc1OC
3-chloro-5-(trifluoromethyl)-N-[(E)-(4,5-dimethoxyphenyl)methylideneamino]pyridin-2-amine