Problem statement: Answer the multiple choice question.
Query: Which drug has a 5.398\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1cc(OC)cc(C(=O)Nc2ccccc2-c2nnn(CC(N)=O)n2)c1
b. OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
c. CCOCCCNC(=O)c1c[nH]c2c(CC)cccc2c1=O
d. CCOC(=O)C1(Cc2ccc(OC)cc2)CCN(C(=O)CCc2cccnc2)CC1
e. COc1ccc(N2CCN(C(=O)CC(C)S(=O)(=O)c3ccc4c(c3)NC(=O)CO4)CC2)cc1
Answer: e. COc1ccc(N2CCN(C(=O)CC(C)S(=O)(=O)c3ccc4c(c3)NC(=O)CO4)CC2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(N2CCN(C(=O)CC(C)S(=O)(=O)c3ccc4c(c3)NC(=O)CO4)CC2)cc1
COc1ccc(N2CCN(C(=O)CC(C)S(=O)(=O)c3ccc4c(c3)NC(=O)CO4)CC2)cc1
6-[4-[4-(4-methoxyphenyl)piperazin-1-yl]-4-oxobutan-2-yl]sulfonyl-4H-1,4-benzoxazin-3-one