Problem statement: Answer the multiple choice question.
Query: Which drug has a -12.154\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) O=C(Nc1ccnn1C1CCN(CCCc2ccccc2)CC1)c1ccccc1Cl
b.) CC(C)OS(C)(=O)=O
c.) O=C(c1ccc(Cl)cc1)N1CCCC(C(=O)N2CCN(c3ccccc3)CC2)C1
d.) COc1ccc(C)cc1Nc1c2c(nc3ccccc13)CCC2
e.) O=C1N(Cc2ccc(F)cc2Cl)c2ccccc2C12OCCCO2
Answer: c. O=C(c1ccc(Cl)cc1)N1CCCC(C(=O)N2CCN(c3ccccc3)CC2)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(c1ccc(Cl)cc1)N1CCCC(C(=O)N2CCN(c3ccccc3)CC2)C1
O=C(c1ccc(Cl)cc1)N1CCCC(C(=O)N2CCN(c3ccccc3)CC2)C1
[1-(4-chlorobenzoyl)piperidin-3-yl]-(4-phenylpiperazin-1-yl)methanone