Problem statement: Answer the MCQ question.
Query: Which drug has a -1.843\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. CC1CC(C)CN(C(=O)c2cc(-c3ccncc3)nc3ccccc23)C1
b. CC(C)c1cc(Br)c(NC(=O)Nc2cccnc2)c(Br)c1
c. COc1ccccc1N(CC(=O)N1CCN(c2ccc(F)cc2)CC1)S(=O)(=O)c1ccc(C)cc1
d. COc1ccc2c(CC(=O)N3CCN(S(=O)(=O)c4ccc(F)cc4)CC3)coc2c1
e. CCC(C)NC(=O)C1CCC(CNS(=O)(=O)c2ccccc2)CC1
Answer: a. CC1CC(C)CN(C(=O)c2cc(-c3ccncc3)nc3ccccc23)C1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CC1CC(C)CN(C(=O)c2cc(-c3ccncc3)nc3ccccc23)C1
CC1CC(C)CN(C(=O)c2cc(-c3ccncc3)nc3ccccc23)C1
(3,5-dimethylpiperidin-1-yl)-(2-pyridin-4-ylquinolin-4-yl)methanone