Problem statement: Answer the multiple-choice question.
Query: Which drug has a -19.426\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) c1nc(N2CCC3(CC2)OCCO3)c2[nH]cnc2n1
b) COc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)COC(=O)C1COc2ccccc2O1
c) COc1ccc(-c2nc(NC(=O)CSCCO)sc2C)cc1
d) CCOC(=O)C1CCN(C(=O)c2c(C)oc3c2C(=O)c2ccccc2C3=O)CC1
e) COc1ccc(CCC2(C)NC(=O)N(C(C)C(=O)Nc3ccccc3F)C2=O)cc1
Answer: e. COc1ccc(CCC2(C)NC(=O)N(C(C)C(=O)Nc3ccccc3F)C2=O)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CCC2(C)NC(=O)N(C(C)C(=O)Nc3ccccc3F)C2=O)cc1
COc1ccc(CCC2(C)NC(=O)N(C(C)C(=O)Nc3ccccc3F)C2=O)cc1
N-(2-fluorophenyl)-2-[4-[2-(4-methoxyphenyl)ethyl]-4-methyl-2,5-dioxoimidazolidin-1-yl]propanamide