Problem statement: Answer the multiple-choice question.
Question: Which drug has a 13.898\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a: Cc1c(C)n(Cc2ccccc2)c2ccc(C(=O)OCCCN(C)C)cc12
b: COC(=O)Cn1c(CN(C)Cc2ccccc2)nc2c1c(=O)n(C)c(=O)n2C
c: COc1ccc(CN2CCN(Cc3cn(C)nc3-c3ccccc3)CC2CCO)c(C)c1C
d: NC(=O)c1ccsc1NC(=O)c1coc2ccccc2c1=O
e: CC(=O)c1nc(N2C(=O)CC(Cc3ccccc3)C2=O)sc1C
Answer: b. COC(=O)Cn1c(CN(C)Cc2ccccc2)nc2c1c(=O)n(C)c(=O)n2C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)Cn1c(CN(C)Cc2ccccc2)nc2c1c(=O)n(C)c(=O)n2C
COC(=O)Cn1c(CN(C)Cc2ccccc2)nc2c1c(=O)n(C)c(=O)n2C
methyl 2-[8-[[benzyl(methyl)amino]methyl]-1,3-dimethyl-2,6-dioxopurin-7-yl]acetate