Problem statement: Answer the MCQ question.
Question: Which compound has a -14.283\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a O=C(c1ccccc1Br)N1CCN(Cc2ccc3c(c2)OCO3)CC1
b COc1ccc2c(c1)C1NC(=S)NC(C)(O2)C1C(=O)Nc1ccc(C)cc1C
c CCOC(=O)C1(Cc2cccc(F)c2)CCN(Cc2c(C)nn(CC)c2C)CC1
d COc1ccc2nc(C)cc(NCCN3CCOCC3)c2c1
e C=CCNC(=O)COC(=O)c1oc2ccccc2c1CSC1CCCCC1
Answer: c. CCOC(=O)C1(Cc2cccc(F)c2)CCN(Cc2c(C)nn(CC)c2C)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)C1(Cc2cccc(F)c2)CCN(Cc2c(C)nn(CC)c2C)CC1
CCOC(=O)C1(Cc2cccc(F)c2)CCN(Cc2c(C)nn(CC)c2C)CC1
ethyl 1-[(1-ethyl-3,5-dimethylpyrazol-4-yl)methyl]-4-[(3-fluorophenyl)methyl]piperidine-4-carboxylate