Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -20.828\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CCCNC(=S)NC1CC2CCCC(C1)N2Cc1ccc(F)cc1
b. CC(NC(=O)c1ccco1)C(=O)NC(C)c1cc(F)c(Cl)cc1Cl
c. COc1ccc(-c2noc(=O)n2Cc2ccc(C#N)cc2)cc1
d. CS(=O)(=O)Nc1ccc(C2=NN(C(=O)C3CCCCC3)C(c3cccs3)C2)cc1
e. O=C(CSc1nccc(=O)[nH]1)NC1CCCC1
Answer: c. COc1ccc(-c2noc(=O)n2Cc2ccc(C#N)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-c2noc(=O)n2Cc2ccc(C#N)cc2)cc1
COc1ccc(-c2noc(=O)n2Cc2ccc(C#N)cc2)cc1
4-[[3-(4-methoxyphenyl)-5-oxo-1,2,4-oxadiazol-4-yl]methyl]benzonitrile