Problem statement: Answer the multiple choice question.
Question: Which drug has a -3.717\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1cccc(CNC(=O)CN(c2cc(C)cc(C)c2)S(=O)(=O)c2c(C)noc2C)c1
b) COc1ccc(-n2c(Cc3cccn3C)nnc2SCC(=O)NCc2ccc(F)cc2)cc1
c) Cc1cc(OC(=O)c2ccccc2Cl)ccc1N1C(=O)CCC1=O
d) CCCn1c(=O)[nH]c(=O)c2c(C(=O)OCC)cc(-c3cccs3)nc21
e) Cc1ccc(NC(=O)c2oc3ccccc3c2NC(=O)C2CCCO2)cc1C
Answer: b. COc1ccc(-n2c(Cc3cccn3C)nnc2SCC(=O)NCc2ccc(F)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(-n2c(Cc3cccn3C)nnc2SCC(=O)NCc2ccc(F)cc2)cc1
COc1ccc(-n2c(Cc3cccn3C)nnc2SCC(=O)NCc2ccc(F)cc2)cc1
N-[(4-fluorophenyl)methyl]-2-[[4-(4-methoxyphenyl)-5-[(1-methylpyrrol-2-yl)methyl]-1,2,4-triazol-3-yl]sulfanyl]acetamide