Problem statement: Answer the MCQ question.
Question: Which drug has a 8.399\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1cccc(CNC(=O)CCC2CCCN(Cc3cc4ccccc4o3)C2)c1
b) COc1ccccc1N1CC(O)=C(c2nc3ccccc3c(=O)[nH]2)C1=N
c) Cc1ccc(CN(Cc2cc3cccc(C)c3[nH]c2=O)C(=S)NCCCN(C)C)cc1
d) COCCN1C(=O)N[C@@H](c2cccc(C(F)(F)F)c2)C(C(=O)OC)=C1C
e) CC1CC(C)CN(C(=O)C(C)N2CCN(S(=O)(=O)c3cccs3)CC2)C1
Answer: b. COc1ccccc1N1CC(O)=C(c2nc3ccccc3c(=O)[nH]2)C1=N
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1N1CC(O)=C(c2nc3ccccc3c(=O)[nH]2)C1=N
COc1ccccc1N1CC(O)=C(c2nc3ccccc3c(=O)[nH]2)C1=N
2-[3-hydroxy-5-imino-1-(2-methoxyphenyl)-2H-pyrrol-4-yl]-3H-quinazolin-4-one