Problem statement: Answer the multiple-choice question.
Query: Which drug has a 12.807\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] O=C(NCc1ccc(-c2csnn2)cc1)c1cc(Cl)cc(Cl)c1
[b] Cn1nc(-c2ccccc2)c(-c2nc(-c3cccc(Cl)c3)no2)c1Cl
[c] O=C(CSc1ncc(C(F)(F)F)cc1Cl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
[d] Oc1ccccc1/C=N/Nc1cc(N2CCCC2)nc(N2CCCC2)n1
[e] O=C(NC1CCCc2ccccc21)c1ccc(CNc2c(N3CCOCC3)c(=O)c2=O)cc1
Answer: c. O=C(CSc1ncc(C(F)(F)F)cc1Cl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(CSc1ncc(C(F)(F)F)cc1Cl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
O=C(CSc1ncc(C(F)(F)F)cc1Cl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
1-[4-(4-chlorophenyl)sulfonylpiperazin-1-yl]-2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanylethanone