Problem statement: Answer the multiple-choice question.
Query: Which compound exhibits a 8.218\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a. CCOc1ccc(Nc2oc(-c3cccc(Cl)c3)nc2C#N)cc1
b. COC(=O)c1[nH]c2c(c1C)C(=O)CC(c1ccc(C)cc1)C2
c. NC(=O)c1ccsc1NC(=O)CCS(=O)(=O)c1ccc(F)cc1
d. C=CCn1c(N2CCOCC2)nc2c1c(=O)[nH]c(=O)n2C
Answer: b. COC(=O)c1[nH]c2c(c1C)C(=O)CC(c1ccc(C)cc1)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1[nH]c2c(c1C)C(=O)CC(c1ccc(C)cc1)C2
COC(=O)c1[nH]c2c(c1C)C(=O)CC(c1ccc(C)cc1)C2
methyl 3-methyl-6-(4-methylphenyl)-4-oxo-1,5,6,7-tetrahydroindole-2-carboxylate