Problem statement: Answer the MCQ question.
Question: Which compound has a -13.854\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a: COC(=O)c1ccc(CO/N=C/c2ccc(OC)cc2)o1
b: N#CCC(=O)N/N=C\c1ccc(OC/C=C/c2ccccc2)cc1
c: O=C(Nc1cccnc1)c1cnn2c(C(F)F)cc(C3CC3)nc12
d: COc1ccccc1C(CC(=O)c1ccccc1)CC(=O)c1ccccc1
Answer: c. O=C(Nc1cccnc1)c1cnn2c(C(F)F)cc(C3CC3)nc12
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(Nc1cccnc1)c1cnn2c(C(F)F)cc(C3CC3)nc12
O=C(Nc1cccnc1)c1cnn2c(C(F)F)cc(C3CC3)nc12
5-cyclopropyl-7-(difluoromethyl)-N-pyridin-3-ylpyrazolo[1,5-a]pyrimidine-3-carboxamide