Problem statement: Answer the MCQ question.
Query: Which compound has a 10.604\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COC(=O)c1ccc(/C=C2/SC(=S)N(CCC(=O)N3CCOCC3)C2=O)cc1
b Nc1c(Br)c(=O)[nH]c(=O)n1-c1ccccc1
c Cc1nn(CC(=O)NCc2cccc3ccccc23)c(=O)c2ccccc12
d CCCCNC(=O)[C@@H]1CSC2c3ccccc3C(=O)N21
e Cc1nnc(SCC(=O)N(CC(C)C)c2c(N)n(Cc3ccccc3)c(=O)[nH]c2=O)n1N
Answer: e. Cc1nnc(SCC(=O)N(CC(C)C)c2c(N)n(Cc3ccccc3)c(=O)[nH]c2=O)n1N
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1nnc(SCC(=O)N(CC(C)C)c2c(N)n(Cc3ccccc3)c(=O)[nH]c2=O)n1N
Cc1nnc(SCC(=O)N(CC(C)C)c2c(N)n(Cc3ccccc3)c(=O)[nH]c2=O)n1N
N-(6-amino-1-benzyl-2,4-dioxopyrimidin-5-yl)-2-[(4-amino-5-methyl-1,2,4-triazol-3-yl)sulfanyl]-N-(2-methylpropyl)acetamide