Problem statement: Answer the multiple choice question.
Query: Which drug has a 11.794\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. Cn1c(=O)[nH]c(=O)c2c1nc(Br)n2CCCCSc1nc2ccccc2o1
b. Cc1ccc([C@@H]2[C@@H]3C(=O)N(C)C(=O)[C@@H]3[C@]3(C)C(=O)N(Cc4ccccc4)CC(=O)N23)o1
c. N#C/C(=C\c1cn(Cc2ccccc2F)c2ccccc12)C(=O)NCc1ccco1
d. COc1ccccc1CNC(=O)c1ccc(N(C)S(=O)(=O)c2ccc(C)cc2)cc1
e. CC(C)C(=O)Nc1cc2c(cc1C(=O)c1ccccc1)OCCO2
Answer: d. COc1ccccc1CNC(=O)c1ccc(N(C)S(=O)(=O)c2ccc(C)cc2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccccc1CNC(=O)c1ccc(N(C)S(=O)(=O)c2ccc(C)cc2)cc1
COc1ccccc1CNC(=O)c1ccc(N(C)S(=O)(=O)c2ccc(C)cc2)cc1
N-[(2-methoxyphenyl)methyl]-4-[methyl-(4-methylphenyl)sulfonylamino]benzamide