Task: Answer the multiple-choice question.
Query: Which drug exhibits a -14.818\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Cc1[nH]nc2c1C(c1cccs1)C1=C(CC(C)(C)CC1=O)N2
b COC(=O)CN(c1cc(Cl)ccc1OC)S(=O)(=O)c1ccc(C)cc1
c Cc1c(C(=O)NCc2ccco2)oc2c(F)cccc12
d Fc1ccc(NC(=S)Nc2ccccc2N2CCOCC2)cc1Cl
e CCCc1cc(C(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)sc1C
Answer: e. CCCc1cc(C(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)sc1C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCc1cc(C(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)sc1C
CCCc1cc(C(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)sc1C
(5-methyl-4-propylthiophen-2-yl)-[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methanone