Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -4.038\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1ccc(OC(C)C(=O)NC2CCCCCC2)cc1
b. COc1ccc2cc(C(C)c3nc4ccccc4c(=O)n3N)ccc2c1
c. CCOC(=O)[C@H]1[C@H]2COc3ccc(Cl)cc3[C@@H]2N2C(=O)CN(Cc3ccc(C)cc3)C(=O)[C@@]12C
d. CCCCC(c1nnnn1CCOC)N1CCN(CC)CC1.Cl
e. Cc1ccc(CSc2nc3nc(C)cc(C)c3c(=O)[nH]2)cc1
Answer: e. Cc1ccc(CSc2nc3nc(C)cc(C)c3c(=O)[nH]2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(CSc2nc3nc(C)cc(C)c3c(=O)[nH]2)cc1
Cc1ccc(CSc2nc3nc(C)cc(C)c3c(=O)[nH]2)cc1
5,7-dimethyl-2-[(4-methylphenyl)methylsulfanyl]-3H-pyrido[2,3-d]pyrimidin-4-one