Problem statement: Answer the multiple choice question.
Query: Which drug has a 12.723\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(NC(=O)CN(C)C(=O)c2ccc3c(c2)S(=O)(=O)N=C2CCCCCN23)cc1
b. Cc1cccc(NC(=O)c2sccc2-n2cccc2)c1C
c. COCCNC(=O)c1ccc(-n2c(SCc3ccncc3)nc3ccccc3c2=O)cc1
d. CCOC(=O)N1CCN(C(=O)C2CCC(=O)N(CCc3ccccc3)C2)CC1
e. C[n+]1c2n(c3ccccc31)N=C(c1ccc(Cl)cc1)CS2.[Br-]
Answer: d. CCOC(=O)N1CCN(C(=O)C2CCC(=O)N(CCc3ccccc3)C2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)N1CCN(C(=O)C2CCC(=O)N(CCc3ccccc3)C2)CC1
CCOC(=O)N1CCN(C(=O)C2CCC(=O)N(CCc3ccccc3)C2)CC1
ethyl[4-[6-oxo-1-(2-phenylethyl)piperidine-3-carbonyl]piperazin-1-yl]formate