Problem statement: Answer the MCQ question.
Query: Which compound exhibits a -8.381\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COCC(C)NC(=O)Cn1c(SCc2ccccc2)nc2ccccc21
b. COc1cccc(NC(=O)CN(C)C(=O)/C=C/c2ccc3ccccc3n2)c1
c. COc1ccccc1OCCn1cc(C#N)c2ccccc21
d. CCCc1nn2c(=O)cc(COc3ccc(NC(=O)c4ccco4)cc3)nc2s1
e. O=C(Nc1cccnc1Cl)c1cc(-c2ccc(F)cc2)on1
Answer: d. CCCc1nn2c(=O)cc(COc3ccc(NC(=O)c4ccco4)cc3)nc2s1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCCc1nn2c(=O)cc(COc3ccc(NC(=O)c4ccco4)cc3)nc2s1
CCCc1nn2c(=O)cc(COc3ccc(NC(=O)c4ccco4)cc3)nc2s1
N-[4-[(5-oxo-2-propyl-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-yl)methoxy]phenyl]furan-2-carboxamide