Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -1.650\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] O=C(Cc1ccc(Br)cc1)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1
[b] O=C(NC1CCCCC1)C1CCCN1S(=O)(=O)c1ccc(Cl)cc1
[c] C=CCOc1c(Cl)cc(CNn2cn[nH]c2=S)cc1OC
[d] S=c1[nH]nc(COc2ccccc2)n1/N=C/c1ccc(Cl)c(Cl)c1
[e] O=C(COc1ccccc1Cl)N1CCN(c2ccc(F)cc2)CC1
Answer: e. O=C(COc1ccccc1Cl)N1CCN(c2ccc(F)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
O=C(COc1ccccc1Cl)N1CCN(c2ccc(F)cc2)CC1
O=C(COc1ccccc1Cl)N1CCN(c2ccc(F)cc2)CC1
2-(2-chlorophenoxy)-1-[4-(4-fluorophenyl)piperazin-1-yl]ethanone