Problem statement: Answer the multiple choice question.
Query: Which drug has a -23.521\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1ccc(Br)cc1S(=O)(=O)NCc1ccccn1
[b] CCCCn1c(SCC(N)=O)nc2ccc(N3CCOCC3)cc2c1=O
[c] CCC(CC)CN1C(Nc2ccccc2)=NC[C@@H]1CC(C)C
[d] c1ccc(-c2nnc(N3CCN(c4ccccc4)CC3)nc2-c2ccccc2)cc1
[e] O=C(Cc1ccc(F)cc1)NCCS(=O)(=O)N1CCN(c2ccccc2)CC1
Answer: c. CCC(CC)CN1C(Nc2ccccc2)=NC[C@@H]1CC(C)C
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCC(CC)CN1C(Nc2ccccc2)=NC[C@@H]1CC(C)C
CCC(CC)CN1C(Nc2ccccc2)=NC[C@@H]1CC(C)C
(5S)-1-(2-ethylbutyl)-5-(2-methylpropyl)-N-phenyl-4,5-dihydroimidazol-2-amine