Problem statement: Answer the multiple-choice question.
Question: Which drug has a -0.517\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1cccc(-c2cccc(NC(=O)C3CCN(CC4CCOC4)CC3)c2)c1
b CN(C)c1cc(-c2ccc(Br)cc2)oc(=O)c1Cl
c CC1(c2nnc(-c3ccc(Cl)cc3)o2)CC(c2ccncc2)=NO1
d CCOc1cc2c(C#N)c(N3CCCCC3)nc(N)c2c(N)n1
e Cc1cc(C)c(S(=O)(=O)NCc2ccc3c(c2)cc(C)n3C)c(C)c1
Answer: a. COc1cccc(-c2cccc(NC(=O)C3CCN(CC4CCOC4)CC3)c2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(-c2cccc(NC(=O)C3CCN(CC4CCOC4)CC3)c2)c1
COc1cccc(-c2cccc(NC(=O)C3CCN(CC4CCOC4)CC3)c2)c1
N-[3-(3-methoxyphenyl)phenyl]-1-(oxolan-3-ylmethyl)piperidine-4-carboxamide