Task: Answer the multiple-choice question.
Query: Which drug has a -18.754\% hERG inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CCOC(=O)c1c(NC(=O)c2ccc(Cl)s2)sc(C)c1C
b.) CC(C)/C=C/C(=O)N1CCC(N2CCC(C(=O)N3CCOCC3)CC2)CC1
c.) COc1cc(OC)cc(C(=O)NCCCN2CCN(CCCNC(=O)c3cc(OC)cc(OC)c3)CC2)c1
d.) COc1ccc(N2CC(C(=O)OCC(=O)Nc3cccc(C)c3)CC2=O)cc1
e.) O=C(NCc1cccnc1)C(=O)NCC1OCCCN1S(=O)(=O)c1ccc(F)cc1
Answer: c. COc1cc(OC)cc(C(=O)NCCCN2CCN(CCCNC(=O)c3cc(OC)cc(OC)c3)CC2)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cc(OC)cc(C(=O)NCCCN2CCN(CCCNC(=O)c3cc(OC)cc(OC)c3)CC2)c1
COc1cc(OC)cc(C(=O)NCCCN2CCN(CCCNC(=O)c3cc(OC)cc(OC)c3)CC2)c1
N-[3-[4-[3-[(3,5-dimethoxybenzoyl)amino]propyl]piperazin-1-yl]propyl]-3,5-dimethoxybenzamide