Problem statement: Answer the multiple-choice question.
Query: Which drug has a -4.540\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] Cc1ccc(S(=O)(=O)NCC(=O)OC(C)C(=O)Nc2ncc(Cl)cc2Cl)cc1
[b] Cc1ccc(C(=O)NC2CCCN(c3ccc(C(F)(F)F)cn3)C2)cn1
[c] CCn1cc(C(=O)N2CCN(c3ccccc3F)CC2)c(=O)c2ccc(C)nc21
[d] COCc1ccc(C(=O)N2CCCC(C(=O)c3ccc(Cl)cc3C)C2)o1
[e] COc1cc(OC)c(OC)cc1CN1CCN(C(=O)Cc2ccccc2)CC1.O=C(O)C(=O)O
Answer: a. Cc1ccc(S(=O)(=O)NCC(=O)OC(C)C(=O)Nc2ncc(Cl)cc2Cl)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(S(=O)(=O)NCC(=O)OC(C)C(=O)Nc2ncc(Cl)cc2Cl)cc1
Cc1ccc(S(=O)(=O)NCC(=O)OC(C)C(=O)Nc2ncc(Cl)cc2Cl)cc1
[1-[(3,5-dichloropyridin-2-yl)amino]-1-oxopropan-2-yl] 2-[(4-methylphenyl)sulfonylamino]acetate