Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 0.144\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) CCCOc1ccc(/C(O)=C2/C(=O)C(=O)N(CCN(C)C)C2c2ccc(OC)c(OC)c2)cc1
(b) N#CC1=C(N)Oc2c(c(=O)oc3ccccc23)C1c1ccncc1
(c) CNS(=O)(=O)c1cccc(C(=O)OCC(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)c1
(d) COC(=O)[C@H](C)NC(=O)NC1CCN(Cc2ccccc2)CC1
(e) O=C(Nc1ccc(F)cc1F)c1c(C(F)(F)F)ccnc1Oc1ccc(Cl)cc1
Answer: d. COC(=O)[C@H](C)NC(=O)NC1CCN(Cc2ccccc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)[C@H](C)NC(=O)NC1CCN(Cc2ccccc2)CC1
COC(=O)[C@H](C)NC(=O)NC1CCN(Cc2ccccc2)CC1
methyl (2S)-2-[(1-benzylpiperidin-4-yl)carbamoylamino]propanoate