Problem statement: Answer the multiple-choice question.
Query: Which drug exhibits a 18.807\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(CCNCc2ccccn2)cc1OC
b. C[C@@H](C(=O)NCc1ccc(S(C)(=O)=O)cc1)[C@H]1C[C@]1(C)[C@H](NC(=O)OCc1ccccc1)c1ccccc1
c. COCCNC(=O)/C(C#N)=C\c1ccc(CNS(=O)(=O)c2ccccc2)o1
d. COc1ccc([C@H]2CC(=O)C=C(c3ccc(-c4ccccc4)cc3)C2)cc1OC
e. Cc1oc2c(C)c3oc(=O)c(CCC(=O)N4CCC(C(=O)NCCC(=O)O)(c5ccccc5)CC4)c(C)c3cc2c1C
Answer: d. COc1ccc([C@H]2CC(=O)C=C(c3ccc(-c4ccccc4)cc3)C2)cc1OC
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc([C@H]2CC(=O)C=C(c3ccc(-c4ccccc4)cc3)C2)cc1OC
COc1ccc([C@H]2CC(=O)C=C(c3ccc(-c4ccccc4)cc3)C2)cc1OC
(5R)-5-(3,4-dimethoxyphenyl)-3-(4-phenylphenyl)cyclohex-2-en-1-one