Problem statement: Answer the multiple-choice question.
Question: Which compound has a 17.864\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) COc1ccc(C(=O)C2CCCN(Cc3cn[nH]c3-c3ccc(F)cc3)C2)cc1OC
(b) CCc1ccc(N(C(=O)c2csnn2)C(C(=O)NC2CCCCC2)c2cccnc2)cc1
(c) CC1=CS/C(=C(/C#N)C(=O)N2CCCCC2)N1c1ccccc1
(d) Cc1cc(C(=O)OCC(=O)NC2CC2)c2ccccc2n1
(e) COc1cccc(C(=O)N2N=C(c3cccc(OC)c3)CC2(O)C(F)(F)F)c1
Answer: e. COc1cccc(C(=O)N2N=C(c3cccc(OC)c3)CC2(O)C(F)(F)F)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1cccc(C(=O)N2N=C(c3cccc(OC)c3)CC2(O)C(F)(F)F)c1
COc1cccc(C(=O)N2N=C(c3cccc(OC)c3)CC2(O)C(F)(F)F)c1
[5-hydroxy-3-(3-methoxyphenyl)-5-(trifluoromethyl)-4H-pyrazol-1-yl]-(3-methoxyphenyl)methanone