Problem statement: Answer the MCQ question.
Question: Which compound has a 3.050\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) Cc1ccc(N=Nc2c(=O)[nH]n3c(=O)cc(C)[nH]c23)cc1
b.) CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)N2CC(=O)Nc3ccccc32)c1C
c.) COC(=O)[C@H](Cc1ccccc1)NC(=O)C1CCN(C(=O)[C@H](C)NS(=O)(=O)c2ccc(C)cc2)CC1
d.) Cc1nc(N)nc(OCC(F)(F)C(F)F)c1Br
e.) CCN(CC)S(=O)(=O)c1cccc(NC(=O)COC(=O)c2cccs2)c1
Answer: c. COC(=O)[C@H](Cc1ccccc1)NC(=O)C1CCN(C(=O)[C@H](C)NS(=O)(=O)c2ccc(C)cc2)CC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)[C@H](Cc1ccccc1)NC(=O)C1CCN(C(=O)[C@H](C)NS(=O)(=O)c2ccc(C)cc2)CC1
COC(=O)[C@H](Cc1ccccc1)NC(=O)C1CCN(C(=O)[C@H](C)NS(=O)(=O)c2ccc(C)cc2)CC1
methyl (2S)-2-[[1-[(2S)-2-[(4-methylphenyl)sulfonylamino]propanoyl]piperidine-4-carbonyl]amino]-3-phenylpropanoate