Problem statement: Answer the MCQ question.
Question: Which compound has a 4.835\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccc(NCc2nnc(SCC(=O)N3CCCc4ccccc43)o2)cc1
[b] CN(Cc1ccccc1)C(=O)Cn1c(=O)c2cccn2c2cccnc21
[c] CCOc1ccc(C(=O)NCC(=O)N2CCc3ccccc3C2)cc1OCC
[d] O=C(COc1cccnc1[N+](=O)[O-])N1CCN(S(=O)(=O)c2ccccc2)CC1
[e] CN1C(=O)C(=O)/C(=C(/O)c2ccc(Br)cc2)C1c1ccccc1F
Answer: e. CN1C(=O)C(=O)/C(=C(/O)c2ccc(Br)cc2)C1c1ccccc1F
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CN1C(=O)C(=O)/C(=C(/O)c2ccc(Br)cc2)C1c1ccccc1F
CN1C(=O)C(=O)/C(=C(/O)c2ccc(Br)cc2)C1c1ccccc1F
(4E)-4-[(4-bromophenyl)-hydroxymethylidene]-5-(2-fluorophenyl)-1-methylpyrrolidine-2,3-dione