Task: Answer the multiple-choice question.
Question: Which compound has a -9.727\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. N#CC(C#N)=C1C=CC=CN1/C(=C\c1ccco1)C(=O)c1ccc(Cl)cc1
b. O=C(Nc1ccc(S(=O)(=O)N2CCCCC2)cc1)c1ccncc1
c. CC(C)COc1ccc(C(=O)Nc2scc(-c3ccc(Cl)cc3Cl)c2C(N)=O)cc1
d. Cc1ccc(S(=O)(=O)c2nc(S(C)(=O)=O)sc2N2CCC3(CC2)OCCO3)cc1
e. Cc1cccc(N2CCN(S(=O)(=O)c3c(C)[nH]c(=O)[nH]c3=O)CC2)c1C
Answer: d. Cc1ccc(S(=O)(=O)c2nc(S(C)(=O)=O)sc2N2CCC3(CC2)OCCO3)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
Cc1ccc(S(=O)(=O)c2nc(S(C)(=O)=O)sc2N2CCC3(CC2)OCCO3)cc1
Cc1ccc(S(=O)(=O)c2nc(S(C)(=O)=O)sc2N2CCC3(CC2)OCCO3)cc1
8-[4-(4-methylphenyl)sulfonyl-2-methylsulfonyl-1,3-thiazol-5-yl]-1,4-dioxa-8-azaspiro[4.5]decane