Problem statement: Answer the MCQ question.
Question: Which drug has a 10.216\% hERG inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(CC(=O)N(C)CC(=O)Nc2ccccc2C(F)(F)F)cc1S(=O)(=O)N1CCOCC1
b. Cc1cc2cc(CNC(=S)NC3CCCCC3)ccc2n1C
c. CCCOc1ncnc2c1[nH]c1ccc(OC)cc12
d. CN1C(=O)C(C)(C)c2cc(S(=O)(=O)N3CCC(C(=O)NCc4ccc(Cl)cc4)CC3)ccc21
e. CC1CCCCC12NC(=O)N(CC(=O)Nc1ccc3c(c1)OCCCO3)C2=O
Answer: a. COc1ccc(CC(=O)N(C)CC(=O)Nc2ccccc2C(F)(F)F)cc1S(=O)(=O)N1CCOCC1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(CC(=O)N(C)CC(=O)Nc2ccccc2C(F)(F)F)cc1S(=O)(=O)N1CCOCC1
COc1ccc(CC(=O)N(C)CC(=O)Nc2ccccc2C(F)(F)F)cc1S(=O)(=O)N1CCOCC1
2-(4-methoxy-3-morpholin-4-ylsulfonylphenyl)-N-methyl-N-[2-oxo-2-[2-(trifluoromethyl)anilino]ethyl]acetamide