Problem statement: Answer the multiple-choice question.
Question: Which compound has a -80.203\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. CN(C)/C=C(\C#N)C(=O)N/N=C/c1ccc(Cl)cc1
b. COCCNC(=S)N1CCN(c2nc(-c3cccc(OC)c3)cs2)CC1
c. CCOC(=O)c1c(NC(=S)Nc2ccccc2)sc2c1CCN(CC)C2
d. O=C(CSc1ccc2ccccc2c1)NCCc1ccc(O)c(O)c1
e. COc1ccc(NS(=O)(=O)c2ccc(N3CCCC3)c(NC(=S)Nc3cccc(S(=O)(=O)N(C)C)c3)c2)cc1
Answer: c. CCOC(=O)c1c(NC(=S)Nc2ccccc2)sc2c1CCN(CC)C2
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
CCOC(=O)c1c(NC(=S)Nc2ccccc2)sc2c1CCN(CC)C2
CCOC(=O)c1c(NC(=S)Nc2ccccc2)sc2c1CCN(CC)C2
ethyl 6-ethyl-2-(phenylcarbamothioylamino)-5,7-dihydro-4H-thieno[2,3-c]pyridine-3-carboxylate