Task: Answer the multiple-choice question.
Question: Which compound has a 1.487\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
(a) Cc1cn2c(N)c(/C=C3\C=Nc4ccccc43)c(=O)nc2s1
(b) Cc1ccc(NS(=O)(=O)c2ccc(C)c(C(=O)NCC(c3ccccc3)N(C)C)c2)cc1
(c) O=C(COc1ccc(C(=S)N2CCCC2)cc1)Nc1ccccc1C(F)(F)F
(d) COc1ccc([C@H]2CC(=O)C=C(c3ccc(Cl)c(C(F)(F)F)c3)C2)cc1
(e) CNC(=S)Nc1cccc(Cl)c1C
Answer: d. COc1ccc([C@H]2CC(=O)C=C(c3ccc(Cl)c(C(F)(F)F)c3)C2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc([C@H]2CC(=O)C=C(c3ccc(Cl)c(C(F)(F)F)c3)C2)cc1
COc1ccc([C@H]2CC(=O)C=C(c3ccc(Cl)c(C(F)(F)F)c3)C2)cc1
(5R)-3-[4-chloro-3-(trifluoromethyl)phenyl]-5-(4-methoxyphenyl)cyclohex-2-en-1-one