Problem statement: Answer the multiple-choice question.
Question: Which drug exhibits a -4.374\% human ether-à-go-go related gene (hERG) inhibition at 1uM?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) COc1ccc(NS(=O)(=O)c2cccc(C(=O)NCC3(N4CCCCC4)CCCCC3)c2)cc1
b) Cc1cc(C)n(-c2nc3ccccc3c(=O)n2OCC(N)=O)n1
c) Cc1cc(S(=O)(=O)NCC(C)C)ccc1OCC(=O)NCc1ccco1
d) Cc1cc(C)c(NC(=O)c2ccc(CNS(=O)(=O)c3cc(C(F)(F)F)ccc3Cl)cc2)c(C)c1
e) O=C(CSc1nc2ccccc2c(=O)n1-c1ccccc1)N1CCCC1
Answer: a. COc1ccc(NS(=O)(=O)c2cccc(C(=O)NCC3(N4CCCCC4)CCCCC3)c2)cc1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COc1ccc(NS(=O)(=O)c2cccc(C(=O)NCC3(N4CCCCC4)CCCCC3)c2)cc1
COc1ccc(NS(=O)(=O)c2cccc(C(=O)NCC3(N4CCCCC4)CCCCC3)c2)cc1
3-[(4-methoxyphenyl)sulfamoyl]-N-[(1-piperidin-1-ylcyclohexyl)methyl]benzamide