Problem statement: Answer the MCQ question.
Query: Which drug exhibits a -0.586\% human ether-à-go-go related gene (hERG) inhibition at a concentration of 1uM?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a O=C(NCCCn1ccnc1)C(=O)NCC(c1ccco1)N1CCN(c2ccccc2)CC1
b CC1(C)CC(=O)c2c(O)c(-c3ccccc3)c(=O)n(-c3ccccc3)c2C1
c COC(=O)c1cc(Br)c(=O)n(Cc2ccc3c(c2)OCO3)c1
d Clc1cccc(-c2cc3nc4c(c(N5CCN(c6cnccn6)CC5)n3n2)CCCC4)c1
Answer: c. COC(=O)c1cc(Br)c(=O)n(Cc2ccc3c(c2)OCO3)c1
{#Task|Problem statement!}: Answer the {#multiple choice|multiple-choice|MCQ!} question.
{#Question|Query!}: Which {#compound|drug!} {#has|exhibits!} a {herg_central_at_1uM#}{herg_central_at_1uM__units} {herg_central_at_1uM__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_central_at_1uM%}
Answer: {%multiple_choice_result}. {SMILES#}
COC(=O)c1cc(Br)c(=O)n(Cc2ccc3c(c2)OCO3)c1
COC(=O)c1cc(Br)c(=O)n(Cc2ccc3c(c2)OCO3)c1
methyl 1-(1,3-benzodioxol-5-ylmethyl)-5-bromo-6-oxopyridine-3-carboxylate