User: I want to come up with a SMILES.
Assistant: This sounds very exciting. Should I consider any constraints for the creation?
User: Yes, please. The molecule should not be a human ether-à-go-go related gene (hERG) blocker (<10uM).
Assistant: Got it, here you go, this SMILES is not a human ether-à-go-go related gene (hERG) blocker (<10uM): O=C1[C@H](Cc2ccc(O)cc2)N2C(=O)CCN(C(=O)NCc3ccccc3)[C@H]2CN1Cc1cccc2ccccc12
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {herg_blocker#not &NULL}be a {herg_blocker__names__noun}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {herg_blocker#not &NULL}a {herg_blocker__names__noun}: {SMILES#}
(6S,9aS)-N-benzyl-6-[(4-hydroxyphenyl)methyl]-8-(naphthalen-1-ylmethyl)-4,7-dioxo-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide