Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 cell effective permeability?
Constraint: Even if you are uncertain, you must pick either a, b, c, or d without using any additional words.
Options:
a.) CCOC(=O)c1c(Cl)cccc1-c1cnc([C@@H](C)NC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1
b.) CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1
c.) Cn1c(=O)c2c(ncn2C)n(C)c1=O
d.) CCOC(=O)c1c(Cl)cc(Cl)cc1-c1cnc([C@@H](C)NC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1
Answer: a
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
ethyl 2-chloro-6-[5-fluoro-6-[(1R)-1-[[1-[(2,2,2-trifluoroacetyl)amino]cyclopropanecarbonyl]amino]ethyl]pyridin-3-yl]benzoate