User: I want to create a molecule SMILES.
Assistant: This sounds very interesting. Should I consider any constraints for the generation?
User: Yes, please. The molecule should have a Caco-2 cell effective permeability value of approximately -5.370 cm/s.
Assistant: Ok, this SMILES has a Caco-2 cell effective permeability value of approximately -5.370 cm/s: COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cc(OC)ccc5c4CCN3C[C@H]2C[C@@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should have a {permeability__names__noun} value of approximately {permeability#} {permeability__units}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} has a {permeability__names__noun} value of approximately {permeability#} {permeability__units}: {SMILES#}
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate