Task: Please answer the multiple choice question.
Question: Which molecule has the highest Caco-2 cell effective permeability?
Constraint: Even if you are not sure, you must pick either a, b, c, or d without using any other words.
Options:
a. CN1[C@@H]2CC[C@@H]1CC(OC(=O)C(CO)c1ccccc1)C2
b. NC(N)=NC(=O)c1nc(Cl)c(N)nc1N
c. CN(C)CC/C=C1/c2ccccc2Sc2ccc(Cl)cc21
d. O=C1CN=C(c2ccccn2)c2cc(Br)ccc2N1
Answer: b
Task: Please answer the multiple choice question.
Question: Which molecule has the highest {permeability__names__noun}?
Constraint: Even if you are {#uncertain|not sure!}, you must pick either {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%permeability%}
Answer: {%multiple_choice_result}
3,5-diamino-6-chloro-N-(diaminomethylidene)pyrazine-2-carboxamide