Task: Please generate a SMILES based on the description below.
Description: A molecule with a Caco-2 cell effective permeability of approximately -4.330 cm/s.
Result: C=C1C[C@@H]2[C@H](CC[C@]3(C)C(=O)CC[C@@H]23)[C@@]2(C)C=CC(=O)C=C12
Task: Please {#give me|create|generate!} a {#molecule |!}{SMILES__description} based on the {#text |!}description{# below|!}.
Description: A molecule with a {permeability__names__noun} of approximately {permeability#} {permeability__units}.
Result: {SMILES#}
(8R,9S,10R,13S,14S)-10,13-dimethyl-6-methylidene-7,8,9,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,17-dione