Task: Please create a SMILES based on the text description.
Description: A molecule with a Caco-2 cell permeability of approximately -4.819 cm/s.
Result: COC(=O)C1=CO[C@@H](C)[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@@H]12
Task: Please {#give me|create|generate!} a {#molecule |!}{SMILES__description} based on the {#text |!}description{# below|!}.
Description: A molecule with a {permeability__names__noun} of approximately {permeability#} {permeability__units}.
Result: {SMILES#}
methyl(1S,15R,16S,20R)-16-methyl-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,18-pentaene-19-carboxylate