Q: help me identify which of the options below have a aqueous solubility in pH 7.4 buffer at 20 deg C of 3.146 log(microM).
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options: [a] C[C@@H](NC(=O)C1(N)CCN(c2ncnc3[nH]ccc23)CC1)c1ccc(Cl)cc1
[b] COc1cc2c(Nc3cc(CC(=O)Nc4cccc(F)c4F)[nH]n3)ncnc2cc1OCCCN1CCC(CCO)CC1
[c] CS(=O)(=O)Cc1cc(N2CCOCC2)nc(-c2cnc3[nH]ccc3c2)n1
[d] C[C@@H]1CN(c2nc(N3CCOCC3)c3ccc(Nc4ccccc4)nc3n2)C[C@H](C)O1
[e] COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)/C=C/CN1CCCCC1
Answer: d
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
C[C@@H]1CN(c2nc(N3CCOCC3)c3ccc(Nc4ccccc4)nc3n2)C[C@H](C)O1
C[C@@H]1CN(C[C@H](C)O1)c2nc(N3CCOCC3)c4ccc(Nc5ccccc5)nc4n2
2-[(2S,6R)-2,6-dimethylmorpholin-4-yl]-4-morpholin-4-yl-N-phenylpyrido[2,3-d]pyrimidin-7-amine