Question: help me identify which of the options below have a solubility in aqueous pH 7.4 buffer at 20 deg C of 4.360 log(microM).
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options: a.) COc1cc2c(Nc3cc(CC(=O)Nc4cccc(F)c4F)[nH]n3)ncnc2cc1OCCCN(CCO)CC(C)C
b.) C[C@@H]1CN(C(=O)OCC(F)(F)F)CCN1c1ncc(OCc2ccncc2C#N)cn1
c.) O=C(c1nnsc1S(=O)(=O)c1ccc(Cl)cc1)N1CCOCC1
d.) O=C(NCc1ccc(C(=O)NO)cc1)OCc1cccnc1
Answer: b
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
C[C@@H]1CN(C(=O)OCC(F)(F)F)CCN1c1ncc(OCc2ccncc2C#N)cn1
C[C@@H]1CN(CCN1c2ncc(OCc3ccncc3C#N)cn2)C(=O)OCC(F)(F)F
2,2,2-trifluoroethyl (3R)-4-[5-[(3-cyanopyridin-4-yl)methoxy]pyrimidin-2-yl]-3-methylpiperazine-1-carboxylate