Question: help me identify which of the options below have a solubility in aqueous pH 7.4 buffer at 20 deg C of 4.630 log(microM).
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options: a O=C(Nc1ccc(Cl)c(Cl)c1)N1CCN(C[C@@H]2CCCN(Cc3ccccc3)C2)CC1
b COc1cc2ncnc(Nc3ccc(Cl)c(O)c3)c2cc1OC
c COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1
d Cc1nc(-c2ccc(CN3CCC(N(C)C(=O)Cc4ccc(-n5cnnn5)cc4)CC3)cc2)no1
e CC(C)Cn1cnc2c(N)nc3ccccc3c21
Answer: a
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
O=C(Nc1ccc(Cl)c(Cl)c1)N1CCN(C[C@@H]2CCCN(Cc3ccccc3)C2)CC1
Clc1ccc(NC(=O)N2CCN(C[C@@H]3CCCN(Cc4ccccc4)C3)CC2)cc1Cl
4-[[(3R)-1-benzylpiperidin-3-yl]methyl]-N-(3,4-dichlorophenyl)piperazine-1-carboxamide