User: I want to  a drug with a particular solubility in aqueous pH 7.4 buffer at 20 deg C.
Assistant: Great, I would need to know the solubility in aqueous pH 7.4 buffer at 20 deg C of the drug you want to design.
User: The solubility in aqueous pH 7.4 buffer at 20 deg C should be 5.200 log(microM).
Assistant: I propose the drug with the SMILES COc1ncc(-c2cccc3c2C[C@H](NC(=O)c2ccc(COCC(F)(F)F)nc2)CO3)cn1.
User: I want to {#design|discover|find|identify|!} a {#compound|drug|chemical|molecule!} with a particular {target__names__noun}.
Assistant: {#Cool, |Awesome, |Great, |That sounds interesting, |!}I would need to know the {target__names__noun} of the {#compound|drug|chemical|molecule!} you want to design.
User: The {target__names__noun} should be {target#} {target__units}.
Assistant: I {#recommend|suggest|propose|advise|!} the {#compound|drug|chemical|molecule!} with the {SMILES__description} {SMILES#}.
COc1ncc(-c2cccc3c2C[C@H](NC(=O)c2ccc(COCC(F)(F)F)nc2)CO3)cn1
COc1ncc(cn1)c2cccc3OC[C@H](Cc23)NC(=O)c4ccc(COCC(F)(F)F)nc4
N-[(3S)-5-(2-methoxypyrimidin-5-yl)-3,4-dihydro-2H-chromen-3-yl]-6-(2,2,2-trifluoroethoxymethyl)pyridine-3-carboxamide