Question: help me identify which of the options below have a solubility in aqueous pH 7.4 buffer at 20 deg C of 3.342 log(microM).
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options: [a] C[C@H](C#N)NC(=O)[C@@H]1CCCC[C@H]1C(=O)N1CCc2[nH]c3ccc(F)cc3c2C1
[b] NC1(c2ccc(-c3c(-c4ccccc4)ccn4ccnc34)cc2)CCC1
[c] CCOC(=O)c1cc2ccccc2[nH]1
[d] COc1cc2c(Nc3ncc(CNS(=O)(=O)c4cccc(F)c4)s3)ncnc2cc1OCCCN1CCC(CO)CC1
[e] COc1cc(C2CCN(C(C)=O)CC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1
Answer: e
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
COc1cc(C2CCN(C(C)=O)CC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1
COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4ccccn34)C5CCN(CC5)C(=O)C
1-[4-[4-[(5-chloro-4-imidazo[1,2-a]pyridin-3-ylpyrimidin-2-yl)amino]-3-methoxyphenyl]piperidin-1-yl]ethanone