Question: help me identify which of the options below have a solubility in aqueous pH 7.4 buffer at 20 deg C of 3.342 log(microM).
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options: a.) O=C(NC1Cc2ccccc2N(CC(CO)CO)C1=O)c1cc2cc(Cl)ccc2[nH]1
b.) O=C(CO)N1CCC[C@@H]1COc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12
c.) CC(C)C[C@H](N[C@@H](c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1)C(F)(F)F)C(=O)NCC#N
d.) CCc1ccc(NC(=O)c2ccc3cc(C(=N)N)ccc3c2)cc1
Answer: b
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
O=C(CO)N1CCC[C@@H]1COc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12
OCC(=O)N1CCC[C@@H]1COc2cccc3ncnc(Nc4ccc(OCc5ccccn5)c(Cl)c4)c23
1-[(2R)-2-[[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]quinazolin-5-yl]oxymethyl]pyrrolidin-1-yl]-2-hydroxyethanone