Q: help me identify which of the options below have a aqueous solubility in pH 7.4 buffer at 20 deg C of 5.810 log(microM).
Constraint: You must select none, one or more options from a, b, or c without using any other words.
Options: a.) Cc1cccc2c3cc(NC(=O)N4CCOCC4)ccc3n(C(C)C)c12
b.) COC[C@H](C)Oc1cc(O[C@@H](C)Cc2cc(F)cc(F)c2)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1
c.) O=C(NC1Cc2ccccc2N(C[C@@H](O)CO)C1=O)c1cc2cc(Cl)sc2[nH]1
Answer: b
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
COC[C@H](C)Oc1cc(O[C@@H](C)Cc2cc(F)cc(F)c2)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1
COC[C@H](C)Oc1cc(O[C@@H](C)Cc2cc(F)cc(F)c2)cc(c1)C(=O)Nc3ccc(cn3)C(=O)O
6-[[3-[(2S)-1-(3,5-difluorophenyl)propan-2-yl]oxy-5-[(2S)-1-methoxypropan-2-yl]oxybenzoyl]amino]pyridine-3-carboxylic acid