Question: help me identify which of the options below have a solubility in aqueous pH 7.4 buffer at 20 deg C of 4.000 log(microM).
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options: a: Cc1cnc(NC(=O)Cc2ccccc2)s1
b: CN(C(=O)Cc1ccc(S(C)(=O)=O)cc1F)C1CCN(Cc2ccc(C(F)(F)F)cc2)CC1
c: COc1cc(C(=O)N2CCOCC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1
d: Cc1ccc2c(c1)-c1ccccc1S(=O)(=O)N2
e: COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN1CCCC[C@@H]1C(N)=O
Answer: e
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN1CCCC[C@@H]1C(N)=O
COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN4CCCC[C@@H]4C(=O)N
(2R)-1-[[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]methyl]piperidine-2-carboxamide