Question: help me identify which of the options below have a solubility in aqueous pH 7.4 buffer at 20 deg C of 4.350 log(microM).
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options: a) CCC(O)CN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21
b) O=C(CCc1ccncc1)Nc1ccc(C(=O)c2ccccc2)cc1
c) COCCNS(=O)(=O)c1ccc(Nc2nccc(-c3c(C)nc(C)n3C)n2)cc1
d) COc1cnc(Cl)c(Nc2ncnc3cc(OCCN4CCN(C(C)=O)CC4)cc(OC(C)C)c23)n1
e) Cc1c(Oc2ccc(S(C)(=O)=O)cc2F)ncnc1OC1CCN(C(=O)OC(C)C)CC1
Answer: d
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
COc1cnc(Cl)c(Nc2ncnc3cc(OCCN4CCN(C(C)=O)CC4)cc(OC(C)C)c23)n1
COc1cnc(Cl)c(Nc2ncnc3cc(OCCN4CCN(CC4)C(=O)C)cc(OC(C)C)c23)n1
1-[4-[2-[4-[(3-chloro-6-methoxypyrazin-2-yl)amino]-5-propan-2-yloxyquinazolin-7-yl]oxyethyl]piperazin-1-yl]ethanone