Q: help me identify which of the options below have a aqueous solubility in pH 7.4 buffer at 20 deg C of 4.111 log(microM).
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options: a) COc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(OC)n1
b) COCCS(=O)(=O)N1CCN(c2ccc(Nc3nccc(-c4cnc(C)n4C(C)C)n3)cc2)CC1
c) COc1ccc(-c2cc(N)c(C(N)=O)s2)cc1
d) CNCc1ccc(-c2[nH]c3cc(F)cc4c3c2CCNC4=O)cc1
e) CN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)[C@@H]1CCN(Cc2ccc(C(F)(F)F)cc2)C[C@@H]1F
Answer: e
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
CN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)[C@@H]1CCN(Cc2ccc(C(F)(F)F)cc2)C[C@@H]1F
CN([C@@H]1CCN(Cc2ccc(cc2)C(F)(F)F)C[C@@H]1F)C(=O)Cc3ccc(cc3)S(=O)(=O)C
N-[(3S,4R)-3-fluoro-1-[[4-(trifluoromethyl)phenyl]methyl]piperidin-4-yl]-N-methyl-2-(4-methylsulfonylphenyl)acetamide