Q: help me identify which of the options below have a aqueous solubility in pH 7.4 buffer at 20 deg C of 2.778 log(microM).
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options: a) CC(C)N1CCN(Cc2cnc(-c3ccc(C(=O)Nc4ccccc4N)cc3)c(C#N)c2)CC1
b) CN(C)CCOc1ccc(-c2cc(C(N)=O)c(NC(N)=O)s2)cc1
c) COc1cc2c(Nc3ncc(CC(=O)Nc4cccc(F)c4F)s3)ncnc2cc1OCCCN1CCC[C@H]1CO
d) Cc1cccc2c3cc(NC(=O)N4CCOCC4)ccc3n(C(C)C)c12
e) O=C(Nc1ccccc1F)N[C@H]1N=C(c2ccccc2)c2ccccc2NC1=O
Answer: c
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
COc1cc2c(Nc3ncc(CC(=O)Nc4cccc(F)c4F)s3)ncnc2cc1OCCCN1CCC[C@H]1CO
COc1cc2c(Nc3ncc(CC(=O)Nc4cccc(F)c4F)s3)ncnc2cc1OCCCN5CCC[C@H]5CO
N-(2,3-difluorophenyl)-2-[2-[[7-[3-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]propoxy]-6-methoxyquinazolin-4-yl]amino]-1,3-thiazol-5-yl]acetamide