Q: help me identify which of the options below have a solubility in aqueous pH 7.4 buffer at 20 deg C of 5.310 log(microM).
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options: a COc1cc(N2CCN(C(=O)[C@@H]3CCCC[C@H]3C(=O)NC3(C#N)CC3)[C@H](C)C2)ccc1C1CC1
b COc1cc(CCc2cc(Nc3ccnc(NCc4cc(C)on4)n3)n[nH]2)cc(OC)c1
c COc1cc(Nc2cc(Oc3cccnc3C)ccn2)cc(OC)c1OC
d Nc1cccc(NC(=O)c2ccc(CNC(=O)OCc3cccnc3)cc2)c1
e O=C(c1cccs1)C(O)c1cccs1
Answer: a
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
COc1cc(N2CCN(C(=O)[C@@H]3CCCC[C@H]3C(=O)NC3(C#N)CC3)[C@H](C)C2)ccc1C1CC1
COc1cc(ccc1C2CC2)N3CCN([C@H](C)C3)C(=O)[C@@H]4CCCC[C@H]4C(=O)NC5(CC5)C#N
(1R,2R)-N-(1-cyanocyclopropyl)-2-[(2R)-4-(4-cyclopropyl-3-methoxyphenyl)-2-methylpiperazine-1-carbonyl]cyclohexane-1-carboxamide