Question: help me identify which of the options below have a aqueous solubility in pH 7.4 buffer at 20 deg C of 3.531 log(microM).
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options: a.) Fc1ccc(Nc2ncnc3ccccc23)cc1Cl
b.) COc1cc2c(NC(=O)Nc3ccccc3Cl)ncnc2cc1OCC1CCN(C)CC1
c.) O=C(NCCNC(=O)c1cn(-c2ccccc2)nc1C(F)(F)F)c1ccc(Cl)cn1
d.) O=c1[nH]c2c(O)ccc([C@@H](O)CNCCc3cccc(CNCCc4ccccc4Cl)c3)c2s1
Answer: c
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
O=C(NCCNC(=O)c1cn(-c2ccccc2)nc1C(F)(F)F)c1ccc(Cl)cn1
FC(F)(F)c1nn(cc1C(=O)NCCNC(=O)c2ccc(Cl)cn2)c3ccccc3
5-chloro-N-[2-[[1-phenyl-3-(trifluoromethyl)pyrazole-4-carbonyl]amino]ethyl]pyridine-2-carboxamide