Question: help me identify which of the options below have a solubility in aqueous pH 7.4 buffer at 20 deg C of 3.681 log(microM).
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options: a. C#CCN(Cc1ccc2nc(CO)nc(O)c2c1)c1ccc(C(=O)NCc2cccc([N+](=O)[O-])c2)cc1
b. C[C@@H]1CN(c2nc(C(F)(F)F)no2)CCN1c1ncc(OCc2ccncc2C#N)cn1
c. COc1cc2ncnc(Nc3ccc(Oc4ccccc4)cc3)c2cc1OC
d. Cn1c(C#N)ccc1-c1cc(F)c2c(c1)C(C)(C)C(=O)N2
e. CNC(=O)c1ccc(Nc2nccc(-c3cnc(C)n3C(C)C)n2)cc1F
Answer: b
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
C[C@@H]1CN(c2nc(C(F)(F)F)no2)CCN1c1ncc(OCc2ccncc2C#N)cn1
C[C@@H]1CN(CCN1c2ncc(OCc3ccncc3C#N)cn2)c4onc(n4)C(F)(F)F
4-[[2-[(2R)-2-methyl-4-[3-(trifluoromethyl)-1,2,4-oxadiazol-5-yl]piperazin-1-yl]pyrimidin-5-yl]oxymethyl]pyridine-3-carbonitrile