Question: help me identify which of the options below have a aqueous solubility in pH 7.4 buffer at 20 deg C of 4.770 log(microM).
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options: (a) N#CCNC(=O)[C@@H]1CCCC[C@H]1C(=O)N1CCN(c2ccccc2)CC1
(b) CCCNC(=O)Nc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1Cl
(c) COc1cc2cc(-c3ccc(O)cc3O)nc(C)c2cc1OC
(d) O=C(Nc1ccc(Cl)c(Cl)c1)N1CCN(C[C@@H]2CCCN(CCc3ccccc3)C2)CC1
(e) COc1cnc(-c2cccc(F)c2C(F)(F)CNC(=O)c2ccc(COCC(F)(F)F)nc2)cn1
Answer: e
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
COc1cnc(-c2cccc(F)c2C(F)(F)CNC(=O)c2ccc(COCC(F)(F)F)nc2)cn1
COc1cnc(cn1)c2cccc(F)c2C(F)(F)CNC(=O)c3ccc(COCC(F)(F)F)nc3
N-[2,2-difluoro-2-[2-fluoro-6-(5-methoxypyrazin-2-yl)phenyl]ethyl]-6-(2,2,2-trifluoroethoxymethyl)pyridine-3-carboxamide