User: I want to discover a drug with a particular aqueous solubility in pH 7.4 buffer at 20 deg C.
Assistant: I would need to know the aqueous solubility in pH 7.4 buffer at 20 deg C of the drug you want to design.
User: The aqueous solubility in pH 7.4 buffer at 20 deg C should be 3.447 log(microM).
Assistant: I suggest the drug with the SMILES COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1ncc(Cl)c(-c2cnc3c(F)cccn23)n1.
User: I want to {#design|discover|find|identify|!} a {#compound|drug|chemical|molecule!} with a particular {target__names__noun}.
Assistant: {#Cool, |Awesome, |Great, |That sounds interesting, |!}I would need to know the {target__names__noun} of the {#compound|drug|chemical|molecule!} you want to design.
User: The {target__names__noun} should be {target#} {target__units}.
Assistant: I {#recommend|suggest|propose|advise|!} the {#compound|drug|chemical|molecule!} with the {SMILES__description} {SMILES#}.
COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1ncc(Cl)c(-c2cnc3c(F)cccn23)n1
COc1cc(ccc1Nc2ncc(Cl)c(n2)c3cnc4c(F)cccn34)N5CCN(CC5)C(=O)C
1-[4-[4-[[5-chloro-4-(8-fluoroimidazo[1,2-a]pyridin-3-yl)pyrimidin-2-yl]amino]-3-methoxyphenyl]piperazin-1-yl]ethanone