User: I want to find a drug with a particular aqueous solubility in pH 7.4 buffer at 20 deg C.
Assistant: I would need to know the aqueous solubility in pH 7.4 buffer at 20 deg C of the drug you want to design.
User: The aqueous solubility in pH 7.4 buffer at 20 deg C should be 5.450 log(microM).
Assistant: I propose the drug with the SMILES CC(C)(C)c1csc(N2CCN(C(=O)[C@@H]3CCCC[C@H]3C(=O)NC3(C#N)CC3)CC2)n1.
User: I want to {#design|discover|find|identify|!} a {#compound|drug|chemical|molecule!} with a particular {target__names__noun}.
Assistant: {#Cool, |Awesome, |Great, |That sounds interesting, |!}I would need to know the {target__names__noun} of the {#compound|drug|chemical|molecule!} you want to design.
User: The {target__names__noun} should be {target#} {target__units}.
Assistant: I {#recommend|suggest|propose|advise|!} the {#compound|drug|chemical|molecule!} with the {SMILES__description} {SMILES#}.
CC(C)(C)c1csc(N2CCN(C(=O)[C@@H]3CCCC[C@H]3C(=O)NC3(C#N)CC3)CC2)n1
CC(C)(C)c1csc(n1)N2CCN(CC2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4(CC4)C#N
(1R,2R)-2-[4-(4-tert-butyl-1,3-thiazol-2-yl)piperazine-1-carbonyl]-N-(1-cyanocyclopropyl)cyclohexane-1-carboxamide