Question: help me identify which of the options below have a aqueous solubility in pH 7.4 buffer at 20 deg C of 6.030 log(microM).
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options: a. Clc1ccc(-c2nnc(CNC3CC3)o2)cc1
b. Cc1sc(N2CCN(C(=O)[C@@H]3CCCC[C@H]3C(=O)NC3(C#N)CC3)CC2)nc1C(F)(F)F
c. CC(C)S(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)CC1
d. Cn1cc(C2=C(c3cn(C4CCN(Cc5ccccn5)CC4)c4ccccc34)C(=O)NC2=O)c2ccccc21
Answer: b
{#Question:|Q:!} help me identify which of the options below have a {target__names__noun} of {target#} {target__units}.
Constraint: You must select none, one or more options from {%multiple_choice_enum%3-5%aA1} without using any {#other|additional!} words.
Options: {SMILES%target%}
Answer: {%multiple_choice_result}
Cc1sc(N2CCN(C(=O)[C@@H]3CCCC[C@H]3C(=O)NC3(C#N)CC3)CC2)nc1C(F)(F)F
Cc1sc(nc1C(F)(F)F)N2CCN(CC2)C(=O)[C@@H]3CCCC[C@H]3C(=O)NC4(CC4)C#N
(1R,2R)-N-(1-cyanocyclopropyl)-2-[4-[5-methyl-4-(trifluoromethyl)-1,3-thiazol-2-yl]piperazine-1-carbonyl]cyclohexane-1-carboxamide