User: I want to identify a chemical with a particular aqueous solubility in pH 7.4 buffer at 20 deg C.
Assistant: I would need to know the aqueous solubility in pH 7.4 buffer at 20 deg C of the chemical you want to design.
User: The aqueous solubility in pH 7.4 buffer at 20 deg C should be 5.450 log(microM).
Assistant: I suggest the chemical with the SMILES CNC(=O)[C@H]1CCCN1Cc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OC.
User: I want to {#design|discover|find|identify|!} a {#compound|drug|chemical|molecule!} with a particular {target__names__noun}.
Assistant: {#Cool, |Awesome, |Great, |That sounds interesting, |!}I would need to know the {target__names__noun} of the {#compound|drug|chemical|molecule!} you want to design.
User: The {target__names__noun} should be {target#} {target__units}.
Assistant: I {#recommend|suggest|propose|advise|!} the {#compound|drug|chemical|molecule!} with the {SMILES__description} {SMILES#}.
CNC(=O)[C@H]1CCCN1Cc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OC
CNC(=O)[C@H]1CCCN1Cc2cc3c(Nc4cccc(Cl)c4F)ncnc3cc2OC
(2R)-1-[[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]methyl]-N-methylpyrrolidine-2-carboxamide