User: I want to discover a drug with a particular aqueous solubility in pH 7.4 buffer at 20 deg C.
Assistant: Cool, I would need to know the aqueous solubility in pH 7.4 buffer at 20 deg C of the drug you want to design.
User: The aqueous solubility in pH 7.4 buffer at 20 deg C should be 5.740 log(microM).
Assistant: I  the drug with the SMILES COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)C1(C(N)=O)CCN(C(C)C)CC1.
User: I want to {#design|discover|find|identify|!} a {#compound|drug|chemical|molecule!} with a particular {target__names__noun}.
Assistant: {#Cool, |Awesome, |Great, |That sounds interesting, |!}I would need to know the {target__names__noun} of the {#compound|drug|chemical|molecule!} you want to design.
User: The {target__names__noun} should be {target#} {target__units}.
Assistant: I {#recommend|suggest|propose|advise|!} the {#compound|drug|chemical|molecule!} with the {SMILES__description} {SMILES#}.
COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)C1(C(N)=O)CCN(C(C)C)CC1
COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)C4(CCN(CC4)C(C)C)C(=O)N
4-[[4-(3-chloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]methyl-methylamino]-1-propan-2-ylpiperidine-4-carboxamide