User: I want to  a chemical with a particular aqueous solubility in pH 7.4 buffer at 20 deg C.
Assistant: I would need to know the aqueous solubility in pH 7.4 buffer at 20 deg C of the chemical you want to design.
User: The aqueous solubility in pH 7.4 buffer at 20 deg C should be 5.230 log(microM).
Assistant: I recommend the chemical with the SMILES COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OC[C@@H]1CCCN(C)C1.
User: I want to {#design|discover|find|identify|!} a {#compound|drug|chemical|molecule!} with a particular {target__names__noun}.
Assistant: {#Cool, |Awesome, |Great, |That sounds interesting, |!}I would need to know the {target__names__noun} of the {#compound|drug|chemical|molecule!} you want to design.
User: The {target__names__noun} should be {target#} {target__units}.
Assistant: I {#recommend|suggest|propose|advise|!} the {#compound|drug|chemical|molecule!} with the {SMILES__description} {SMILES#}.
COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OC[C@@H]1CCCN(C)C1
COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OC[C@@H]4CCCN(C)C4
N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[[(3R)-1-methylpiperidin-3-yl]methoxy]quinazolin-4-amine