Task: Please estimate if the compound with the SMILES COc1cc(C2CC(=O)N3CN(c4ccccc4C)CSC3=C2C#N)cc(OC)c1OC is an inhibitor of Rho-kinase 2 (ROCK-2).
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-644__names__noun}.
Result: {MUV-644#no&yes}
COc1cc(C2CC(=O)N3CN(c4ccccc4C)CSC3=C2C#N)cc(OC)c1OC
COc1cc(C2CC(=O)N3CN(c4ccccc4C)CSC3=C2C#N)cc(OC)c1OC
3-(2-methylphenyl)-6-oxo-8-(3,4,5-trimethoxyphenyl)-2,4,7,8-tetrahydropyrido[2,1-b][1,3,5]thiadiazine-9-carbonitrile