User: I want to come up with a SMILES.
Assistant: This sounds very exciting. Should I consider any specific points for the creation?
User: Yes, please. The molecule should not be metabolized by CYP3A4.
Assistant: Got it, here you go, this SMILES is not metabolized by CYP3A4: Nc1nc(NC2CC2)c2ncn([C@H]3C=C[C@@H](CO)C3)c2n1
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {CYP3A4_Substrate#not &NULL}be {CYP3A4_Substrate__names__verb}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}: {SMILES#}
[(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol