User: Is the molecule with the SMILES COc1ccc(C(=O)N2CCN(c3ccc4c(c3)CCC(=O)N4)CC2)cc1OC metabolized by CYP P450 3A4?
Assistant: Yes, it is a substrate for CYP P450 3A4.
User: Is the molecule with the {SMILES__description} {SMILES#} {CYP3A4_Substrate__names__verb}?
Assistant: {CYP3A4_Substrate#No&Yes}, it is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}.
6-[4-(3,4-dimethoxybenzoyl)piperazin-1-yl]-3,4-dihydro-1H-quinolin-2-one