Task: Please answer the multiple choice question.
Question: Which molecules are not metabolized by CYP3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1
b) C(=C/c1ccccc1)\CN1CCN(C(c2ccccc2)c2ccccc2)CC1
c) Cc1ccc(-c2nc3ccc(C)cn3c2CC(=O)N(C)C)cc1
d) Clc1ccc(CO[C@@H](Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1
e) CN(C(=O)c1c(O)n(C)c2ccccc2c1=O)c1ccccc1
Answer: a, b, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}
1-[(2R)-2-[(4-chlorophenyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]imidazole