User: Can you estimate if the molecule with the SMILES O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2ncccn2)CC1 is a CYP3A4 substrate?
Assistant: Yes, this molecule is metabolized by CYP P450 3A4.
User: Can you {#tell me|derive|estimate!} if the molecule with the {SMILES__description} {SMILES#} is a {CYP3A4_Substrate__names__noun}?
Assistant: {CYP3A4_Substrate#No&Yes}, this molecule is {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}.
8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione