Task: Please answer the multiple choice question.
Question: Which molecules are not a CYP P450 3A4 substrate?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CCOC(=O)Nc1ccc2c(c1)N(C(=O)CCN1CCOCC1)c1ccccc1S2
b) O=C(N[C@H](Cc1cc(=O)[nH]c2ccccc12)C(=O)O)c1ccc(Cl)cc1
c) Cc1ccc(-c2nc3ccc(C)cn3c2CC(=O)N(C)C)cc1
d) COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1
e) CC/C(=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Answer: a, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}
2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid