User: Can you create the SMILES of a molecule that is a not substrate for CYP3A4?
Assistant: Sure, here you go: Cn1c(=O)[nH]c2ncn(C)c2c1=O
User: Can you {#give me|create|generate!} the {SMILES__description} of a molecule that is a {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__noun}?
Assistant: {#Yes|Of course|Sure|Yes, I'm happy to help!}, here you go: {SMILES#}
1,7-dimethyl-3H-purine-2,6-dione