User: I want to generate a SMILES.
Assistant: This sounds very exciting. Should it be a special one?
User: Yes, the molecule should not be a CYP P450 3A4 substrate.
Assistant: Got it, this SMILES is not a CYP P450 3A4 substrate: COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cc(OC)ccc5c4CCN3C[C@H]2C[C@@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should it be a special {#molecule|one!}?
User: Yes, the molecule should {CYP3A4_Substrate#not &NULL}be a {CYP3A4_Substrate__names__noun}.
Assistant: {#Understood|Got it|Ok!}, this {SMILES__description} is {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}: {SMILES#}
methyl (1R,15S,17R,18R,19S,20S)-6,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate