Task: Please answer the multiple choice question.
Question: Which molecules are a substrate for CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. O=[N+]([O-])O[C@H]1CO[C@H]2[C@@H]1OC[C@H]2O[N+](=O)[O-]
b. C(=C/c1ccccc1)\CN1CCN(C(c2ccccc2)c2ccccc2)CC1
c. COc1ccc(-c2cc(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3o2)cc1O
d. Cc1ccccc1-n1c(C)nc2ccccc2c1=O
e. COc1cc(OC)c(C(=O)CCCN2CCCC2)c(OC)c1
Answer: a, d
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}a {CYP3A4_Substrate__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}
[(3S,3aS,6R,6aS)-3-nitrooxy-2,3,3a,5,6,6a-hexahydrofuro[3,2-b]furan-6-yl] nitrate