Task: Please answer the multiple choice question.
Question: Which molecules are metabolized by CYP P450 3A4?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] CCN(CC)CCCN(c1ccccc1)C1Cc2ccccc2C1
[b] Cc1nnc2n1-c1sc(Br)cc1C(c1ccccc1Cl)=NC2
[c] O=C(NC[C@H]1CCCCN1)c1cc(OCC(F)(F)F)ccc1OCC(F)(F)F
[d] COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cc(OC)ccc5c4CCN3C[C@H]2C[C@@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC
[e] Cn1c(=O)c2[nH]cnc2n(C)c1=O
Answer: b, e
Task: Please answer the multiple choice question.
Question: Which molecules are {CYP3A4_Substrate#not &NULL}{CYP3A4_Substrate__names__verb}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%CYP3A4_Substrate%}
Answer: {%multiple_choice_result}
4-bromo-7-(2-chlorophenyl)-13-methyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaene