Task: Please answer the multiple choice question.
Question: Which molecules are not a hERG blocking compound (<10uM)?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) CN1CCC(COCc2cc(C(F)(F)F)cc(N3CCC(C#N)C3)n2)(c2ccc(F)cc2)CC1
b) COC(=O)C1=C(CN2CCOC[C@H]2C(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1Cl
c) COc1ccc2nccc([C@@H](O)CN3CCC(NCc4ccc5c(c4)OCCO5)CC3)c2c1
d) CCc1ccc(C=C2SC(=S)NC2=O)cc1
e) N#Cc1ccc(C(=O)N2CCN(c3ccc(OCCCN4CCCCCC4)cc3)C(=O)C2)cc1
Answer: b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {herg_blocker#not &NULL}a {herg_blocker__names__noun}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%herg_blocker%}
Answer: {%multiple_choice_result}
4-[4-[4-[3-(azepan-1-yl)propoxy]phenyl]-3-oxopiperazine-1-carbonyl]benzonitrile