Task: Please estimate if the molecule with the SMILES COc1ccc(-c2nn(C)c3sc(C(=O)NCc4ccco4)cc23)cc1OC is a potentiator of the estrogen receptor-alpha-coactivator binding.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-737__names__noun}.
Result: {MUV-737#no&yes}
COc1ccc(-c2nn(C)c3sc(C(=O)NCc4ccco4)cc23)cc1OC
COc1ccc(-c2nn(C)c3sc(C(=O)NCc4ccco4)cc23)cc1OC
3-(3,4-dimethoxyphenyl)-N-(furan-2-ylmethyl)-1-methylthieno[2,3-c]pyrazole-5-carboxamide