Task: Please estimate if the compound with the SMILES COc1cc(OC)c(C2C(C(=O)O)c3ccccc3C(=O)N2C)cc1OC is a potentiator of the estrogen receptor-alpha-coactivator binding.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-737__names__noun}.
Result: {MUV-737#no&yes}
COc1cc(OC)c(C2C(C(=O)O)c3ccccc3C(=O)N2C)cc1OC
COc1cc(OC)c(C2C(C(=O)O)c3ccccc3C(=O)N2C)cc1OC
2-methyl-1-oxo-3-(2,4,5-trimethoxyphenyl)-3,4-dihydroisoquinoline-4-carboxylic acid