Task: Please estimate if the compound with the SMILES COc1ccccc1CNC(=O)C1CCN(S(=O)(=O)c2cccc3cccnc23)CC1 is a potentiator of the estrogen receptor-alpha-coactivator binding.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-737__names__noun}.
Result: {MUV-737#no&yes}
COc1ccccc1CNC(=O)C1CCN(S(=O)(=O)c2cccc3cccnc23)CC1
COc1ccccc1CNC(=O)C1CCN(S(=O)(=O)c2cccc3cccnc23)CC1
N-[(2-methoxyphenyl)methyl]-1-quinolin-8-ylsulfonylpiperidine-4-carboxamide