Task: Answer the following question about the molecule with SMILES CCc1nc(N)nc(N)c1-c1ccc(Cl)cc1.
Question: Please describe this drug.
Completion: Pyrimethamine is a synthetic derivative of ethyl-pyrimidine with potent antimalarial properties.  Pyrimethamine is a competitive inhibitor of dihydrofolate reductase (DHFR).  DHFR is a key enzyme in the redox cycle for production of tetrahydrofolate, a cofactor that is required for the synthesis of DNA and proteins.  This agent is often used in combination with other antimalarials for the treatment of uncomplicated falciparum malaria. (NCI04)
Task: Answer the following question about the molecule with {SMILES__description} {SMILES#}.
{#Description|Question|Request!}: {quest#}
{#Result|Answer|Completion!}: {answ#}
CCc1nc(N)nc(N)c1-c1ccc(Cl)cc1
CCC1=C(C(=NC(=N1)N)N)C2=CC=C(C=C2)Cl
5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine
Please describe this drug.
Pyrimethamine is a synthetic derivative of ethyl-pyrimidine with potent antimalarial properties.  Pyrimethamine is a competitive inhibitor of dihydrofolate reductase (DHFR).  DHFR is a key enzyme in the redox cycle for production of tetrahydrofolate, a cofactor that is required for the synthesis of DNA and proteins.  This agent is often used in combination with other antimalarials for the treatment of uncomplicated falciparum malaria. (NCI04)