Task: Please determine if the molecule with the SMILES COC(=O)c1cc(=O)nc2sc(-c3cccs3)nn12 is an inhibitor of the estrogen receptor-alpha-coactivator binding.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-733__names__noun}.
Result: {MUV-733#no&yes}
COC(=O)c1cc(=O)nc2sc(-c3cccs3)nn12
COC(=O)c1cc(=O)nc2sc(-c3cccs3)nn12
methyl 7-oxo-2-thiophen-2-yl-[1,3,4]thiadiazolo[3,2-a]pyrimidine-5-carboxylate