Task: Please estimate if the compound with the SMILES COc1cc(C(=O)Nc2nnc(-c3sccc3C)s2)cc(OC)c1OC is a potentiator of the estrogen receptor-alpha-coactivator binding.
Result: yes
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-737__names__noun}.
Result: {MUV-737#no&yes}
COc1cc(C(=O)Nc2nnc(-c3sccc3C)s2)cc(OC)c1OC
COc1cc(C(=O)Nc2nnc(-c3sccc3C)s2)cc(OC)c1OC
3,4,5-trimethoxy-N-[5-(3-methylthiophen-2-yl)-1,3,4-thiadiazol-2-yl]benzamide