Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier to reach the brain?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a: CN1/C(=C(/O)Nc2ccccn2)C(=O)c2ccccc2S1(=O)=O
b: CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1
c: CN(C)CCN1C(=O)CC(c2ccccc2)Sc2ccccc21
d: Cn1c(=O)c2[nH]cnc2n(C)c1=O
Answer: a, d
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}