Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier to reach the brain?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
[a] CN(C(=O)Cc1ccccc1N)[C@@H](CN1CC[C@@H](O)C1)c1ccccc1
[b] O=C(O)/C=C\C(=O)O.c1csc(Cc2ccccc2OCC2CNCCO2)c1
[c] CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1
[d] Cc1ncc(CSSCc2cnc(C)c(O)c2CO)c(CO)c1O
Answer: a
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}