Task: Please answer the multiple choice question.
Question: Which molecules are penetrating the blood brain barrier?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] O=C1CCCN1CCCCN1CCN(c2cc(C(F)(F)F)cc(Cl)n2)CC1
[b] Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1
[c] COC(=O)[C@H]1[C@H]2C[C@@H]3c4[nH]c5cc(OC)ccc5c4CCN3C[C@H]2C[C@@H](OC(=O)c2cc(OC)c(OC)c(OC)c2)[C@@H]1OC
[d] COc1cccc([C@@]2(O)CCCC[C@@H]2CN(C)C)c1.[Cl-].[H+]
[e] CN(C)CCC=C1c2ccccc2Sc2ccccc21
Answer: a, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}