Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier to reach the brain?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) OC(c1ccccc1)(c1ccccc1)C1CCCCN1
b) CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)Cc3cccs3)[C@H]2SC1
c) CCCCCC(N)C(O)(c1ccccc1)c1ccccc1
d) OC1CCN(c2ccc(-c3ccccc3Cl)nn2)CC1
e) Nc1nc(=S)c2[nH]cnc2[nH]1
Answer: b, e
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}