Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier to reach the brain?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a.) CCC(=O)N(c1ccccc1)C1(COC)CCN(CCc2cccs2)CC1
b.) N#Cc1cc(-c2ccccc2)nnc1NCCN1CCOCC1
c.) CCC1(c2ccccc2)C(=O)NCNC1=O
d.) Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1
e.) CN1CCN(c2ccccc2Cc2ccccc2)CC1
Answer: d
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}