Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a.) CN(C)c1cnccn1
b.) C[N+](C)([O-])CCCN1c2ccccc2CCc2ccccc21
c.) CC(=O)NNC(=O)CC(O)(c1ccccc1)c1ccccc1
d.) O=C(O)c1cc(=O)c2cc(OCC(O)COc3cccc4oc(C(=O)O)cc(=O)c34)ccc2o1
e.) O=C1CCC2CCC(=O)N12
Answer: d
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}