Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier?
Constraint: You must select none, one or more options from a, b, or c without using any additional words.
Options:
[a] CC[C@@]1(O)C[C@H](OC2CC(N(C)C)C(OC3CC(O)C(OC4CCC(=O)C(C)O4)C(C)O3)C(C)O2)c2c(cc3c(c2O)C(=O)c2c(O)cccc2C3=O)[C@H]1C(=O)OC
[b] CN(C(=O)Cc1ccccc1N)[C@@H](CN1CC[C@@H](O)C1)c1ccccc1
[c] Cc1nc2n(c(=O)c1CCN1CCC(c3noc4cc(F)ccc34)CC1)CCCC2O
Answer: a, b
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}