Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(Cl)cc1
[b] CC(C)c1nc(CN(C)C(=O)N[C@H](C(=O)N[C@@H](Cc2ccccc2)C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OCc2cncs2)C(C)C)cs1
[c] CN1CCC(=C2c3ccccc3CCc3sccc32)CC1
[d] O=[N+]([O-])C1=CC=NC1NCCSCc1ncccc1Br
[e] O=C(CCCN1CC=C(n2c(=O)[nH]c3ccccc32)CC1)c1ccc(F)cc1
Answer: b
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}