Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a Nc1nc(N)c2nc(-c3ccccc3)c(N)nc2n1
b O=C(O)c1cc(=O)c2ccccc2o1
c CC(CN(C)C)OC(C)(c1ccccc1)c1ccc(Cl)cc1
d O=C(Cn1cnnn1)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3nncs3)CS[C@H]12
e Cc1ccccc1N1CCN(CCCOc2ccccn2)CC1
Answer: a, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}