Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
[a] COc1ccc(Cl)c2c1CCCC2N(C)C
[b] CC(CN(C)C)OC(C)(c1ccccc1)c1ccc(Cl)cc1
[c] CON=C(C#N)C1CN2CCC1CC2
[d] OC(c1ccccc1)(c1ccccc1)C1CC1c1ccncc1
[e] Nc1nc(=S)c2[nH]cnc2[nH]1
Answer: b, e
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}