Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier to reach the brain?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a) CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)CSc3ccncc3)[C@H]2SC1
b) CC1=NN(c2ccccc2)C(=O)C1
c) CCc1ccccc1-n1c(C)nc2ccccc2c1=O
d) Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1
Answer: a, d
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}