Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier?
Constraint: You must select none, one or more options from a or b without using any additional words.
Options:
a: O=C1NCCN1C1CCN(CCC2COc3ccccc3O2)CC1
b: CC[C@H]1OC(=O)[C@H](C)[C@@H](OC2CC(C)(OC)C(O)C(C)O2)C(C)[C@@H](OC2OC(C)CC(N(C)C)C2O)[C@](C)(O)C[C@@H](C)/C(=N\OC)[C@H](C)[C@@H](O)[C@]1(C)O
Answer: b
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}