The molecule with the SMILES COC1=C(C(=O)O)N2C(=O)C(NC(=O)C(N)C3C=CCC=C3)C2SC1 is not penetrating the blood brain barrier to reach the brain.
The molecule with the {SMILES__description} {SMILES#} is {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}.