Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a.) COC1=C(C(=O)O)N2C(=O)C(NC(=O)C(N)C3C=CCC=C3)C2SC1
b.) NC(=O)c1ccc(F)c2c1C[C@@H](N(C1CCC1)C1CCC1)CO2
c.) COc1cc(C(=O)N2CCCCCCC2)cc(OC)c1OC
d.) CC(C)(C)NCC(O)COc1cccc2c1C[C@H](O)[C@H](O)C2
Answer: a
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}