Task: Please answer the multiple choice question.
Question: Which molecules are penetrating the blood brain barrier to reach the brain?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1cccc([C@@]2(O)CCCC[C@@H]2CN(C)C)c1.[Cl-].[H+]
b CC/C(=C(\c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
c OCCN1CCN(CC/C=C2/c3ccccc3Sc3ccc(Cl)cc32)CC1
d COc1cc(C(=O)OCCN2CCN(CCCN3c4ccccc4Sc4ccc(Cl)cc43)CC2)cc(OC)c1OC
e CCCCCC(N)C(O)(c1ccccc1)c1ccccc1
Answer: a, b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}