Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier to reach the brain?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. Cc1ccc(Cc2ccccc2)c(N2CCNCC2)c1
b. Cc1nnc(SCC2=C(C(=O)[O-])N3C(=O)[C@@H](NC(=O)Cn4cnnn4)[C@H]3SC2)s1.[Na+]
c. CNC1Cc2ccccc2N(C)c2ccccc21
d. CN(C)C/C=C(/c1ccc(Br)cc1)c1cccnc1
e. CN(C)CCN1C(=O)CC(c2ccccc2)Sc2ccccc21
Answer: b
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}