Task: Please answer the multiple choice question.
Question: Which molecules are not penetrating the blood brain barrier?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a.) CCCCN/C(=C1/C=C(Cl)C=CC1=O)c1ccccc1Cl
b.) CC1(C)S[C@@H]2[C@H](NC(=O)C(C(=O)Oc3ccccc3)c3ccccc3)C(=O)N2[C@H]1C(=O)O
c.) COc1cc(C(=O)N2CCCCCCC2)cc(OC)c1OC
d.) Cc1cc(-c2ccccc2)nnc1NCCN1CCOCC1
Answer: b
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}