Task: Please answer the multiple choice question.
Question: Which molecules are penetrating the blood brain barrier to reach the brain?
Constraint: You must select none, one or more options from a, b, c, or d without using any other words.
Options:
a Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1
b CN1C(=O)CN=C(C2=CCCCC2)c2cc([N+](=O)[O-])ccc21
c CC1=C2C(c3cccc(Cl)c3)=NCCN=C2N(C)N1
d CC[C@]1(O)C[C@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C(=O)OC)(c3cc4c(cc3OC)N(C=O)[C@H]3[C@@](O)(C(=O)OC)[C@H](OC(C)=O)[C@]5(CC)C=CCN6CC[C@]43[C@@H]65)C2)C1
Answer: b, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {penetrate_BBB#not &NULL}{penetrate_BBB__names__adjective}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%penetrate_BBB%}
Answer: {%multiple_choice_result}