User: Can you estimate if the molecule with the SMILES COC(=O)C1C(=O)CCC2CN3CCc4c([nH]c5ccccc45)C3CC21 is active against the human immunodeficiency virus?
Assistant: Yes, this molecule is not active against the human immunodeficiency virus.
User: Can you {#tell me|derive|estimate!} if the molecule with the {SMILES__description} {SMILES#} is {activity_HIV__names__adjective}?
Assistant: Yes, this molecule is {activity_HIV#not &NULL}{activity_HIV__names__adjective}.
methyl 18-oxo-3,11,12,14,15,16,17,19,20,21-decahydro-1H-yohimban-19-carboxylate