User: I want to create a molecule SMILES.
Assistant: This sounds very interesting. Should I consider any specific points for the creation?
User: Yes, please. The molecule should not be active against HIV.
Assistant: Got it, this SMILES is not active against HIV: O=C1C2Cc3ccccc3CN2C(=O)N1CN1CCN(CN2C(=O)C3Cc4ccccc4CN3C2=O)CC1
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
2-[[4-[(1,3-dioxo-10,10a-dihydro-5H-imidazo[1,5-b]isoquinolin-2-yl)methyl]piperazin-1-yl]methyl]-10,10a-dihydro-5H-imidazo[1,5-b]isoquinoline-1,3-dione