User: I want to create a SMILES.
Assistant: This sounds very interesting. Should I consider any constraints for the generation?
User: Yes, please. The molecule should not be active against HIV.
Assistant: Got it, this SMILES is not active against HIV: COc1cc2c(cc1O)C1Cc3c(cc(OC)c(OC)c3Oc3cc4c(cc3OC)CCN(C)C4Cc3ccc(O)cc3)C(C2)N1C
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
14-[[1-[(4-hydroxyphenyl)methyl]-6-methoxy-2-methyl-3,4-dihydro-1H-isoquinolin-7-yl]oxy]-5,12,13-trimethoxy-17-methyl-17-azatetracyclo[7.7.1.02,7.010,15]heptadeca-2,4,6,10,12,14-hexaen-4-ol