User: I want to create a molecule SMILES.
Assistant: This sounds very exciting. Should I consider any specific points for the generation?
User: Yes, please. The molecule should not be active against HIV.
Assistant: Got it, here you go, this SMILES is not active against HIV: COc1cc(C)cc2c(-c3c(OC(C)=O)cc(OC(C)=O)c4c3CC(C)N(C(C)=O)C4C)cc(-c3cc(-c4c(OC(C)=O)cc(OC(C)=O)c5c4CC(C)N(C(C)=O)C5C)c4cc(C)cc(OC)c4c3O)c(O)c12
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
[2-acetyl-5-[3-[4-(2-acetyl-6,8-diacetyloxy-1,3-dimethyl-3,4-dihydro-1H-isoquinolin-5-yl)-1-hydroxy-8-methoxy-6-methylnaphthalen-2-yl]-4-hydroxy-5-methoxy-7-methylnaphthalen-1-yl]-8-acetyloxy-1,3-dimethyl-3,4-dihydro-1H-isoquinolin-6-yl] acetate