User: I want to create a SMILES.
Assistant: This sounds very exciting. Should I consider any constraints for the generation?
User: Yes, please. The molecule should not be active against the human immunodeficiency virus.
Assistant: Got it, this SMILES is not active against the human immunodeficiency virus: O=c1c(Sc2c(SCSc3cnc4ccccc4c3Sc3c[nH]c4ccccc4c3=O)cnc3ccccc23)c[nH]c2ccccc12
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
3-[3-[[4-[(4-oxo-1H-quinolin-3-yl)sulfanyl]quinolin-3-yl]sulfanylmethylsulfanyl]quinolin-4-yl]sulfanyl-1H-quinolin-4-one