User: I want to come up with a molecule SMILES.
Assistant: This sounds very exciting. Should I consider any constraints for the creation?
User: Yes, please. The molecule should not be active against HIV.
Assistant: Got it, this SMILES is not active against HIV: N#Cc1c2n(c(=S)n(-c3ccccc3)c1=O)CCCCCCC2
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
3-oxo-2-phenyl-1-sulfanylidene-6,7,8,9,10,11-hexahydro-5H-pyrimido[1,6-a]azonine-4-carbonitrile