User: I want to generate a SMILES.
Assistant: This sounds very interesting. Should I consider any specific points for the generation?
User: Yes, please. The molecule should not be active against HIV.
Assistant: Ok, this SMILES is not active against HIV: CC1(C(=O)O)CCCC2(C)C3CCC4(C=C3CCC12)SCCS4
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
1',4'a-dimethylspiro[1,3-dithiolane-2,7'-3,4,4b,5,6,9,10,10a-octahydro-2H-phenanthrene]-1'-carboxylic acid