User: Is the molecule with the SMILES COC(=O)c1c2c(cc3c1CC1(Cc4ccccc4C1=O)C3)CCC2 active against the human immunodeficiency virus?
Assistant: Yes, it is not active against the human immunodeficiency virus.
User: Is the molecule with the {SMILES__description} {SMILES#} {activity_HIV__names__adjective}?
Assistant: Yes, it is {activity_HIV#not &NULL}{activity_HIV__names__adjective}.
methyl 3-oxospiro[1H-indene-2,6'-2,3,5,7-tetrahydro-1H-s-indacene]-4'-carboxylate