User: I want to create a SMILES.
Assistant: This sounds very exciting. Should I consider any constraints for the generation?
User: Yes, please. The molecule should not be active against HIV.
Assistant: Ok, this SMILES is not active against HIV: COC(=O)CCn1c(=N)[nH]c2c1c(=O)n(C)c(=O)n2C
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}
methyl3-[8-azanylidene-1,3-dimethyl-2,6-bis(oxidanylidene)-9H-purin-7-yl]propanoate