The SMILES O=C(c1ccco1)N1CCN(C(=O)C2CC(c3ccc(Cl)c(Cl)c3)=NO2)CC1 is not modulating the M1 muscarinic receptor activity in a positive allosteric way.
The {#molecule |!}{SMILES__description} {SMILES#} is {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}.