User: I want to create a molecule SMILES.
Assistant: This sounds very exciting. Should I consider any constraints for the creation?
User: Yes, please. The molecule should not be modulating the M1 muscarinic receptor activity in a positive allosteric way.
Assistant: Got it, here you go, this SMILES is not modulating the M1 muscarinic receptor activity in a positive allosteric way: COC(=O)c1ccc(COc2ccc(-c3nn[nH]n3)cc2)cc1
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should I consider any {#constraints|specific points!} for the {#generation|creation!}?
User: Yes, please. The molecule should {m1_muscarinic_agonist#not &NULL}be {m1_muscarinic_agonist__names__gerund}.
Assistant: {#Ok|Got it!},{# here you go,|!} this {SMILES__description} is {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}: {SMILES#}