Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a. COc1ccccc1C(=O)N1CCN(c2nc3cc(C)c(C)cc3cc2C#N)CC1
b. COc1cccc(-n2nnc3c(=O)n(CC(=O)NC4CCCC4)cnc32)c1
c. CC(=O)c1cccc(NC(=O)Nc2cc3sccc3n2C)c1
d. COc1ccc(Cl)cc1S(=O)(=O)N1CCN(C)CC1
e. Cc1cc(NS(=O)(=O)c2ccc(Br)s2)no1
Answer: a, b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}