Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a COc1ccccc1NC(=O)N(Cc1cc2cc(OC)c(OC)cc2[nH]c1=O)CC1CCCO1
b O=S(=O)(NCCOCC(F)(F)C(F)F)c1ccc2oc3ccccc3c2c1
c O=C(CN1C(=O)CCC1=O)Nc1ccc(S(=O)(=O)N2CCOCC2)cc1
d CCCCn1c(N)c(C(=O)NCCN2CCOCC2)c2nc3ccccc3nc21
Answer: a, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}