Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1ccc(-n2ncc3c(NCc4cccs4)ncnc32)cc1
b O=C(O)c1ccccc1S(=O)(=O)NCC(O)COc1ccc(Br)cc1
c COc1cc(NC(=O)c2cc(-c3ccco3)on2)c(OC)cc1Cl
d COc1ccc(C(=O)NCCn2cc(SCC(=O)Nc3cc(C)on3)c3ccccc32)cc1OC
e O=C(C1=C(O)C(=O)N(CCN2CCOCC2)C1c1ccncc1)c1ccco1
Answer: a, b, c, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}