Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. O=C(C1CCN(S(=O)(=O)N2CCOCC2)CC1)N1CCN(Cc2ccc3c(c2)OCO3)CC1
b. COc1ccc(Nc2nc(N)nc(C(F)(F)F)n2)c(OC)c1
c. c1ccc(N(c2ccccc2)c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cc1
d. O=C(CCn1nnc2ccccc21)Nc1nnc(COc2ccc(F)cc2)s1
e. Cc1cc(NC(=O)c2cc(CC(C)C)on2)no1
Answer: a, b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}