Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
[a] CCCN1CC=C2C(C#N)=C(N)C(C#N)(C#N)C(c3cc(OC)ccc3OC)C2C1
[b] CC(=O)c1cccc(NC(=O)C2CCN(S(C)(=O)=O)CC2)c1
[c] Cn1nnc2cc(C(=O)Nc3cccnc3)ccc21
[d] O=C(Nc1cnc2ccccc2c1)C1COc2ccccc2O1
[e] CCCS(=O)(=O)c1nnnn1-c1cccc(OC)c1
Answer: b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}