Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a COc1ccc(CCNC(=O)c2ccc(CNc3c(N4CCOCC4)c(=O)c3=O)cc2)cc1OC
b CCc1nnc(NC(=O)CSc2nnc(Cc3ccccc3)n2-c2ccc(OC)cc2)s1
c Brc1ccc2oc3c(N4CCOCC4)ncnc3c2c1
d COc1cc(C(=O)NCc2ccco2)cc(OC)c1OC
e C=CCn1cc(C(=O)NCCCOCC)c(=O)c2cc(S(=O)(=O)N(CC)CC)ccc21
Answer: a, b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}