Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C(CSc1nc(=O)cc(-c2ccccc2)[nH]1)Nc1ccccn1
b) COc1ccc(C2C(=O)c3ccccc3C2=O)c(OC)c1
c) c1ccc(-c2nc(N3CCN(c4ccccc4)CC3)nc(-n3ccnc3)n2)cc1
d) COc1cccc(NC(=O)C(C#N)Cc2ccncc2)c1
e) COc1cccc(C2=CC(c3ccc(C)cc3)N3NC=NC3=N2)c1
Answer: a, b, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}