Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
a) O=C1C=C(NCc2ccco2)CCC1
b) O=C(CSc1nc(-c2ccco2)cc(C(F)(F)F)n1)Nc1cccnc1
c) Brc1ccc(Nc2c3c(nc4ncnn24)CCC3)cc1
d) CCOc1ccc2[nH]c(=O)c(CN(Cc3ccco3)C(CC)c3nnnn3Cc3ccccc3)cc2c1
e) Cn1c(=O)c2c(nc(CN3CCN(CCO)CC3)n2Cc2ccccc2Cl)n(C)c1=O
Answer: a, b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}