Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a COc1ccccc1OCC(=O)OCC(=O)Nc1ncc(Cl)cc1Cl
b Cn1c(SCC(=O)N2CCCCCC2)nc2c([nH]c3ccccc32)c1=O
c COc1cccc(-c2nnc3sc(-c4ccc(Cl)cc4)nn23)c1
d CCCN1CC=C2C(C#N)=C(N)C(C#N)(C#N)C(c3cc(OC)ccc3OC)C2C1
e CC1(C)Nc2ccc(O)cc2-c2c1ssc2=S
Answer: a, b, c, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}