Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a) O=C(NC1CCCCC1)c1cccc(S(=O)(=O)N2CCOCC2)c1
b) COC(=O)c1ccccc1N1C(=O)C2ON=C(c3ccc(F)cc3)C2C1=O
c) CCOC(=O)C1CCN(S(=O)(=O)c2ccc(NC(=O)OC)cc2)CC1
d) O=C1C=CC=C/C1=C1/C=C(C(F)(F)C(F)F)NCCN1
e) CCN(C(=O)c1coc(=O)c(Br)c1)c1ccc2c(c1)OCO2
Answer: a, b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}