Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, or d without using any additional words.
Options:
a COc1ccc(-c2ccc(-c3noc(-c4ccc(OC)c(OC)c4)n3)c(OC)n2)cc1
b COc1ccc(N2CC(C(=O)OCC(=O)c3cccc(OC)c3)CC2=O)cc1
c CCOc1cc(C(=O)OCc2ccc(C(=O)OC)o2)cc(Br)c1OC
d CCOC(=O)c1[nH]cnc1C(=O)Nc1cccc(N)n1
Answer: a, b, c, d
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}