Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any other words.
Options:
a. COc1ccc(Cc2nc(-c3ccc(Br)o3)no2)cc1OC
b. COc1cccc(OC)c1C(=O)Nc1ccc(CN2CCCCC2)cc1
c. CCOC(=O)CCn1nc(-c2ccccc2)cc1N
d. CCSc1cc(C2C(C(=O)OC)=C(C)NC3=C2C(=O)CCC3)c(C)o1
e. Cc1nc2c3c4c(sc3n3c(SCC(=O)NCc5ccco5)nnc3n2n1)COC(C)(C)C4
Answer: a, b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}