Task: Please answer the multiple choice question.
Question: Which molecules are not modulating the M1 muscarinic receptor activity in a positive allosteric way?
Constraint: You must select none, one or more options from a, b, c, d, or e without using any additional words.
Options:
(a) CCOC(=O)C1CCCCC12C(C#N)=C(N)Oc1n[nH]c(C)c12
(b) CCc1ccc(-c2nc(CN3CCC(C(=O)NCCc4ccc(OC)c(OC)c4)CC3)c(C)o2)cc1
(c) COc1ccccc1-c1nc(C(F)(F)F)c(OC)o1
(d) CCOC(=O)CCc1n[nH]c(=O)[nH]c1=O
(e) COc1ccccc1C(=O)Nc1cccc(N(C)S(C)(=O)=O)c1
Answer: a, b, c, d, e
Task: Please answer the multiple choice question.
Question: Which molecules are {m1_muscarinic_agonist#not &NULL}{m1_muscarinic_agonist__names__gerund}?
Constraint: You must select none, one or more options from {%multiple_choice_enum%2-5%aA1} without using any {#other|additional!} words.
Options:
{SMILES%m1_muscarinic_agonist%}
Answer: {%multiple_choice_result}