Task: Please estimate if the molecule with the SMILES COC(=O)c1ccc(COc2ncnc3c(Cl)cc(Cl)cc23)o1 is an agonist of the S1P1 receptor.
Result: no
Task: Please {#determine|predict|estimate!} if the {#molecule|compound!} with the {SMILES__description} {SMILES#} is {MUV-466__names__noun}.
Result: {MUV-466#no&yes}
COC(=O)c1ccc(COc2ncnc3c(Cl)cc(Cl)cc23)o1
COC(=O)c1ccc(COc2ncnc3c(Cl)cc(Cl)cc23)o1
methyl 5-[(6,8-dichloroquinazolin-4-yl)oxymethyl]furan-2-carboxylate