User: I want to come up with a SMILES.
Assistant: This sounds very exciting. Should it be a special one?
User: Yes, the molecule should not be active against HIV.
Assistant: Ok, this SMILES is not active against HIV: N#Cc1cccc(N2C(=O)c3c(c(-c4ccccc4)c(-c4ccc(Sc5ccc(-c6c(-c7ccccc7)c7c(c(-c8ccccc8)c6-c6ccccc6)C(=O)N(c6cccc(C#N)c6)C7=O)cc5)cc4)c(-c4ccccc4)c3-c3ccccc3)C2=O)c1
User: I want to {#come up with|create|generate!} a {#molecule |!}{SMILES__description}.
Assistant: {#This sounds very exciting. |This sounds very interesting. !}Should it be a special {#molecule|one!}?
User: Yes, the molecule should {activity_HIV#not &NULL}be {activity_HIV__names__adjective}.
Assistant: {#Understood|Got it|Ok!}, this {SMILES__description} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}: {SMILES#}