The SMILES COC(=O)C(C#N)=C1c2ccccc2Oc2ccccc21 is not active against HIV.
The {#molecule |!}{SMILES__description} {SMILES#} is {activity_HIV#not &NULL}{activity_HIV__names__adjective}.
[C][O][C][=Branch1][C][=O][C][Branch1][Ring1][C][#N][=C][C][=C][C][=C][C][=C][Ring1][=Branch1][O][C][=C][C][=C][C][=C][Ring1][=Branch1][Ring1][=C]